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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 108706112.

The association of E2F1 and E2F2 single nucleotide polymorphisms with laryngeal squamous cell carcinoma pathomorphological features

Tomas Jakstas, Agne Bartnykaite, Evaldas Padervinskis, Aurelija Vegiene, Elona Juozaityte, Virgilijus Uloza, Rasa Ugenskiene

BMC Cancer. 2024; 24: 214. Published online 2024 Feb 15. doi: 10.1186/s12885-024-11953-z

PMCID:: PMC10870611

Abstract Article PDF–1.1M

Select item 107526803.

DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression

Rui Hua, Qingjun Chu, Feiyan Guo, Qinjie Chen, Maocai Li, Xuan Zhou, Yongtong Zhu

Anal Cell Pathol (Amst) 2023; 2023: 1477658. Published online 2023 Dec 20. doi: 10.1155/2023/1477658

PMCID:: PMC10752680

Abstract Article PDF–1.5M

Select item 102650944.

Tumor‐Associated Macrophage‐Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC‐I Expression

Junjun Li, Keshan Wang, Chao Yang, Kai Zhu, Cheng Jiang, Minjie Wang, Zijie Zhou, Nan Tang, Qiangping Wang, Siqi Wang, Pengwei Shu, Hongliang Yuan, Zhiyong Xiong, Jinsong Li, Tao Liang, Jin Rao, Xuan Wang, Xiaobing Jiang

Adv Sci (Weinh) 2023 Jun; 10(17): 2207067. Published online 2023 Apr 25. doi: 10.1002/advs.202207067

PMCID:: PMC10265094

Abstract Article PDF–5.7M

Select item 99148995.

C/EBPβ Coupled with E2F2 Promoted the Proliferation of hESC-Derived Hepatocytes through Direct Binding to the Promoter Regions of Cell-Cycle-Related Genes

Shoupei Liu, Jue Wang, Sen Chen, Zonglin Han, Haibin Wu, Honglin Chen, Yuyou Duan

Cells. 2023 Feb; 12(3): 497. Published online 2023 Feb 2. doi: 10.3390/cells12030497

PMCID:: PMC9914899

Abstract Article PDF–7.2M

Select item 96672536.

Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy

Ting-Ting Liu, Heng Yang, Fang-Fang Zhuo, Zhuo Yang, Mei-Mei Zhao, Qiang Guo, Yang Liu, Dan Liu, Ke-Wu Zeng, Peng-Fei Tu

eBioMedicine. 2022 Dec; 86: 104353. Published online 2022 Nov 11. doi: 10.1016/j.ebiom.2022.104353

PMCID:: PMC9667253

Abstract Article PDF–3.3M

Select item 95996437.

Molecular Regulation of Heme Oxygenase-1 Expression by E2F Transcription Factor 2 in Lung Fibroblast Cells: Relevance to Idiopathic Pulmonary Fibrosis

Qinmao Ye, Sarah J. Taleb, Heather Wang, Narasimham L. Parinandi, Daniel J. Kass, Mauricio Rojas, Cankun Wang, Qin Ma, Jing Zhao, Yutong Zhao

Biomolecules. 2022 Oct; 12(10): 1531. Published online 2022 Oct 21. doi: 10.3390/biom12101531

PMCID:: PMC9599643

Abstract Article PDF–3.1M

Select item 94985928.

Alteration of E2F2 Expression in Governing Endothelial Cell Senescence

Hongfei Liu, Liping Chen, Wanli Xiao, Jiankun Liu, Changkun Long, Wenxing Zhan, Cui Cui, Lin Yang, Shenghan Chen

Genes (Basel) 2022 Sep; 13(9): 1522. Published online 2022 Aug 24. doi: 10.3390/genes13091522

PMCID:: PMC9498592

Abstract Article PDF–3.5M

Select item 92745039.

E2F2 promotes lung adenocarcinoma progression through B-Myb- and FOXM1-facilitated core transcription regulatory circuitry

Kailong Du, Shijie Sun, Tinghui Jiang, Tao Liu, Xiaofeng Zuo, Xing Xia, Xianjun Liu, Yitao Wang, Youquan Bu

Int J Biol Sci. 2022; 18(10): 4151–4170. Published online 2022 Jun 25. doi: 10.7150/ijbs.72386

PMCID:: PMC9274503

Abstract Article PDF–6.1M

Select item 843692210.

Mediation of circ_RPPH1 on miR-146b-3p/E2F2 pathway to hinder the growth and metastasis of breast carcinoma cells

Hai Feng, Shou-Zhan Sun, Fang Cheng, Nian-Qu Zhang

Aging (Albany NY) 2021 Aug 31; 13(16): 20552–20568. Published online 2021 Aug 25. doi: 10.18632/aging.203439

PMCID:: PMC8436922

Abstract Article PDF–1.8M

Select item 820283411.

E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer

Hui Li, Shufen Zhao, Liwei Shen, Peige Wang, Shihai Liu, Yingji Ma, Zhiwei Liang, Gongjun Wang, Jing Lv, Wensheng Qiu

Aging (Albany NY) 2021 May 31; 13(10): 13626–13643. Published online 2021 Apr 21. doi: 10.18632/aging.202891

PMCID:: PMC8202834

Abstract Article PDF–1.9M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 802408213.

Selected E2F2 Polymorphisms in Oral and Oropharyngeal Squamous Cell Carcinoma

Karolina Gołąbek, Krzysztof Biernacki, Jadwiga Gaździcka, Joanna K. Strzelczyk, Katarzyna Miśkiewicz-Orczyk, Łukasz Krakowczyk, Natalia Zięba, Paweł Kiczmer, Zofia Ostrowska, Maciej Misiołek

Biomed Res Int. 2021; 2021: 8098130. Published online 2021 Mar 30. doi: 10.1155/2021/8098130

PMCID:: PMC8024082

Abstract Article PDF–408K

Select item 800904814.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 759444315.

Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data

Zhili Zeng, Zebiao Cao, Ying Tang

BMC Cancer. 2020; 20: 1037. Published online 2020 Oct 28. doi: 10.1186/s12885-020-07529-2

PMCID:: PMC7594443

Abstract Article PDF–1.6M

Select item 757809416.

Low E2F2 activity is associated with high genomic instability and PARPi resistance

Jonathan P. Rennhack, Eran R. Andrechek

Sci Rep. 2020; 10: 17948. Published online 2020 Oct 21. doi: 10.1038/s41598-020-74877-1

PMCID:: PMC7578094

Abstract Article PDF–1.7M

Select item 694204417.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 659942218.

Long Non-Coding RNA Differentiation Antagonizing Nonprotein Coding RNA (DANCR) Promotes Proliferation and Invasion of Pancreatic Cancer by Sponging miR-214-5p to Regulate E2F2 Expression

Zhichao Yao, Qiyu Chen, Zhonglin Ni, Lei Zhou, Yigeng Wang, Yuetao Yang, He Huang

Med Sci Monit. 2019; 25: 4544–4552. Published online 2019 Jun 19. doi: 10.12659/MSM.916960

PMCID:: PMC6599422

Abstract Article PDF–1.5M

Select item 658846619.

Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs

Linda Clijsters, Claire Hoencamp, Jorg J. A. Calis, Antonio Marzio, Shanna M. Handgraaf, Maria C. Cuitino, Brad R. Rosenberg, Gustavo Leone, Michele Pagano

Mol Cell. Author manuscript; available in PMC 2020 Jun 20.

Published in final edited form as: Mol Cell. 2019 Jun 20; 74(6): 1264–1277.e7. Published online 2019 May 23. doi: 10.1016/j.molcel.2019.04.010

PMCID:: PMC6588466

Abstract Article PDF–2.7M

Select item 623520320.

E2F2 directly regulates the STAT1 and PI3K/AKT/NF-κB pathways to exacerbate the inflammatory phenotype in rheumatoid arthritis synovial fibroblasts and mouse embryonic fibroblasts

Shiguan Wang, Lin Wang, Changshun Wu, Shui Sun, Ji-hong Pan

Arthritis Res Ther. 2018; 20: 225. Published online 2018 Oct 4. doi: 10.1186/s13075-018-1713-x

PMCID:: PMC6235203

Abstract Article PDF–9.0M

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