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Select item 111293571.

Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance

Hatim Boughanem, Jesús pilo, Libia Alejandra García-Flores, Isabel Arranz, María Ramos-Fernandez, María Ortega-Castan, Ana B. Crujeiras, Juan Sandoval, Manuel Macias-Gonzalez

J Transl Med. 2024; 22: 509. Published online 2024 May 27. doi: 10.1186/s12967-024-05329-x

PMCID:: PMC11129357

Abstract Article PDF–2.8M

Select item 104127382.

Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma

Panneerselvam Jayabal, Fuchun Zhou, Xiuye Ma, Kathryn M. Bondra, Barron Blackman, Susan T. Weintraub, Yidong Chen, Patricia Chévez-Barrios, Peter J. Houghton, Brenda Gallie, Yuzuru Shiio

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112103. Published online 2023 Feb 13. doi: 10.1016/j.celrep.2023.112103

PMCID:: PMC10412738

Abstract Article PDF–2.8M

Select item 100531363.

The DNA demethylation-regulated SFRP2 dictates the progression of endometriosis via activation of the Wnt/β-catenin signaling pathway

Mei Yang, Lin Li, Xiaojie Huang, Hui Xing, Li Hong, Chunfan Jiang

BMC Mol Cell Biol. 2023; 24: 12. Published online 2023 Mar 29. doi: 10.1186/s12860-023-00470-9

PMCID:: PMC10053136

Abstract Article PDF–2.9M

Select item 99986504.

Novel method of differentiating human induced pluripotent stem cells to mature cardiomyocytes via Sfrp2

Ying-Chang Hsueh, Richard E. Pratt, Victor J. Dzau, Conrad P. Hodgkinson

Sci Rep. 2023; 13: 3920. Published online 2023 Mar 9. doi: 10.1038/s41598-023-31144-3

PMCID:: PMC9998650

Abstract Article PDF–4.8M

Select item 97774255.

SFRP2 Overexpression Induces an Osteoblast-like Phenotype in Prostate Cancer Cells

Elif Akova Ölken, Attila Aszodi, Hanna Taipaleenmäki, Hiroaki Saito, Veronika Schönitzer, Michael Chaloupka, Maria Apfelbeck, Wolfgang Böcker, Maximilian Michael Saller

Cells. 2022 Dec; 11(24): 4081. Published online 2022 Dec 16. doi: 10.3390/cells11244081

PMCID:: PMC9777425

Abstract Article PDF–4.6M

Select item 94002706.

Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from “first contact” interactions in the tumor microenvironment

Harrys Kishore Charles Jacob, Rossana Signorelli, John Lalith Charles Richard, Tyler Kashuv, Shweta Lavania, Ashley Middleton, Beatriz Aguilar Gomez, Anthony Ferrantella, Haleh Amirian, Junyi Tao, Ayse Burcu Ergonul, Melinda Minucci Boone, Marco Hadisurya, Weiguo Andy Tao, Anton Iliuk, Manoj Kumar Kashyap, Monica Garcia-Buitrago, Rajinder Dawra, Ashok Kumar Saluja

J Exp Clin Cancer Res. 2022; 41: 258. Published online 2022 Aug 24. doi: 10.1186/s13046-022-02425-y

PMCID:: PMC9400270

Abstract Article PDF–4.9M

Select item 86353577.

Downregulation of SFRP2 facilitates cancer stemness and radioresistance of glioma cells via activating Wnt/β-catenin signaling

Quansheng Wu, Xiaofeng Yin, Wenbo Zhao, Wenli Xu, Laizhao Chen

PLoS One. 2021; 16(12): e0260864. Published online 2021 Dec 1. doi: 10.1371/journal.pone.0260864

PMCID:: PMC8635357

Abstract Article PDF–3.8M

Select item 83630988.

SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma

Min Guo, Kaveh M. Goudarzi, Shiva Abedi, Melanie Pieber, Elin Sjöberg, Jinan Behnan, Xing-Mei Zhang, Robert A. Harris, Jiri Bartek, Mikael S. Lindström, Monica Nistér, Daniel Hägerstrand

Oncogene. 2021; 40(32): 5066–5080. Published online 2021 May 21. doi: 10.1038/s41388-021-01825-2

Correction in:: Oncogene. 2021; 40(32): 5153.

PMCID:: PMC8363098

Abstract Article PDF–5.3M

Select item 82679909.

联合检测粪便中ITGA4和SFRP2基因甲基化在大肠肿瘤诊断和预后中的价值

金红, 庞丽莹, 李华洋, 徐明鑫, 闫海润, 李荣辉

Nan Fang Yi Ke Da Xue Xue Bao. 2021 Jun 20; 41(6): 891–897. Chinese. doi: 10.12122/j.issn.1673-4254.2021.06.12

PMCID:: PMC8267990

Abstract Article PDF–1.2M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 789719511.

Secreted frizzled-related protein 2: a key player in noncanonical Wnt signaling and tumor angiogenesis

Karlijn van Loon, Elisabeth J. M. Huijbers, Arjan W. Griffioen

Cancer Metastasis Rev. 2021; 40(1): 191–203. Published online 2020 Nov 2. doi: 10.1007/s10555-020-09941-3

PMCID:: PMC7897195

Abstract Article PDF–3.0M

Select item 785601112.

Stromal upregulation of SOX2 promotes tumorigenesis through the generation of a SFRP1/2-expressing cancer-associated fibroblast population

Hiroaki Kasashima, Angeles Duran, Anxo Martinez-Ordoñez, Yuki Nakanishi, Hiroto Kinoshita, Juan F. Linares, Miguel Reina-Campos, Yotaro Kudo, Antoine L’Hermitte, Masakazu Yashiro, Masaichi Ohira, Fei Bao, Daniele V.F. Tauriello, Eduard Batlle, Maria T. Diaz-Meco, Jorge Moscat

Dev Cell. Author manuscript; available in PMC 2022 Jan 11.

Published in final edited form as: Dev Cell. 2021 Jan 11; 56(1): 95–110.e10. Published online 2020 Nov 17. doi: 10.1016/j.devcel.2020.10.014

PMCID:: PMC7856011

Abstract Article PDF–3.5M

Select item 764211413.

SFRP2 supersedes VEGF as an age-related driver of angiogenesis in melanoma, affecting response to anti-VEGF therapy in older patients.

Mitchell Fane, Brett L. Ecker, Amanpreet Kaur, Gloria E. Marino, Gretchen Alicea, Stephen Douglass, Yash Chhabra, Marie R. Webster, Andrea Marshall, Richard Colling, Olivia Espinosa, Nicholas Coupe, Neera Maroo, Leticia Campo, Mark R. Middleton, Pippa Corrie, Xiaowei Xu, Giorgos C. Karakousis, Ashani T. Weeraratna

Clin Cancer Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Clin Cancer Res. 2020 Nov 1; 26(21): 5709–5719. doi: 10.1158/1078-0432.CCR-20-0446

Correction in:: Clin Cancer Res. 2023 May 15; 29(10): 2012.

PMCID:: PMC7642114

Abstract Article PDF–689K

Select item 759310114.

LUCAT1 Epigenetically Downregulates the Tumor Suppressor Genes CXXC4 and SFRP2 in Gastric Cancer

Hyo Joo Byun, Jung-Ho Yoon, Sang Kil Lee

Yonsei Med J. 2020 Nov 1; 61(11): 923–934. Published online 2020 Oct 22. doi: 10.3349/ymj.2020.61.11.923

Correction in:: Yonsei Med J. 2021 Apr 1; 62(4): 378.

PMCID:: PMC7593101

Abstract Article PDF–2.2M

Select item 756094715.

Gene expression and epigenetic discovery screen reveal methylation of SFRP2 in prostate cancer

Antoinette S. Perry, Gillian O’Hurley, Omer A. Raheem, Kevin Brennan, Simon Wong, Anthony O’Grady, Anne-Marie Kennedy, Laure Marignol, Therese M. Murphy, Linda Sullivan, Ciara Barrett, Barbara Loftus, John Thornhill, Stephen M. Hewitt, Mark Lawler, Elaine Kay, Thomas Lynch, Donal Hollywood

Int J Cancer. Author manuscript; available in PMC 2020 Oct 15.

Published in final edited form as: Int J Cancer. 2013 Apr 15; 132(8): 1771–1780. Published online 2012 Sep 28. doi: 10.1002/ijc.27798

PMCID:: PMC7560947

Abstract Article PDF–1.9M

Select item 744461116.

SFRP2/DPP4 and FMO1/LSP1 define major fibroblast populations in human skin

Tracy Tabib, Christina Morse, Ting Wang, Wei Chen, Robert Lafyatis

J Invest Dermatol. Author manuscript; available in PMC 2020 Aug 24.

Published in final edited form as: J Invest Dermatol. 2018 Apr; 138(4): 802–810. Published online 2017 Dec 6. doi: 10.1016/j.jid.2017.09.045

PMCID:: PMC7444611

Abstract Article PDF–1.0M

Select item 737736417.

The role of secreted frizzled-related protein 2 expression in prostate cancer

Gillian O’Hurley, Antoinette S Perry, Anthony O’Grady, Barbara Loftus, Paul Smyth, John J O’Leary, Orla Sheils, John M Fitzpatrick, Stephen M Hewitt, Mark Lawler, Elaine W Kay

Histopathology. Author manuscript; available in PMC 2020 Jul 23.

Published in final edited form as: Histopathology. 2011 Dec; 59(6): 1240–1248. doi: 10.1111/j.1365-2559.2011.04073.x

PMCID:: PMC7377364

Abstract Article PDF–1.1M

Select item 728575018.

Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer

Hatim Boughanem, Amanda Cabrera-Mulero, Pablo Hernández-Alonso, Mercedes Clemente-Postigo, Felipe F. Casanueva, Francisco José Tinahones, Sonsoles Morcillo, Ana B. Crujeiras, Manuel Macias-Gonzalez

Clin Epigenetics. 2020; 12: 83. Published online 2020 Jun 9. doi: 10.1186/s13148-020-00875-9

PMCID:: PMC7285750

Abstract Article PDF–1.2M

Select item 722955519.

Secreted Frizzled-Related Protein 2 and Extracellular Volume Fraction in Patients with Heart Failure

Shaomin Yang, Haixiong Chen, Kuan Tan, Fusheng Cai, Yongxing Du, Weibiao Lv, Qiugen Hu, Yunzhao Hu, Yuli Huang

Oxid Med Cell Longev. 2020; 2020: 2563508. Published online 2020 May 6. doi: 10.1155/2020/2563508

PMCID:: PMC7229555

Abstract Article PDF–502K

Select item 721830420.

Feasibility of Plasma-Methylated SFRP2 for Early Detection of Gastric Cancer

Jin Miao, Yi Liu, Guodong Zhao, Xiaoyu Liu, Yong Ma, Hui Li, Shiming Li, Yun Zhu, Shangmin Xiong, Minxue Zheng, Sujuan Fei

Cancer Control. 2020 Apr-Jun; 27(2): 1073274820922559. Published online 2020 May 7. doi: 10.1177/1073274820922559

PMCID:: PMC7218304

Abstract Article PDF–523K

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