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Select item 109324021.

Role of CARD9 in Cell- and Organ-Specific Immune Responses in Various Infections

Ji Seok Lee, Chaekyun Kim

Int J Mol Sci. 2024 Mar; 25(5): 2598. Published online 2024 Feb 23. doi: 10.3390/ijms25052598

PMCID:: PMC10932402

Abstract Article PDF–370K

Select item 104315712.

Heterozygous CARD9 mutation favors the development of allergic bronchopulmonary aspergillosis

Xia Xu, Haiwen Lu, Jianxiong Li, Jielin Duan, Zhongwei Wang, Jiawei Yang, Shuyi Gu, Rongguang Luo, Shuo Liang, Wei Tang, Fengying Zhang, Jingqing Hang, Juan Ge, Xin Lin, Jieming Qu, Xinming Jia, Jinfu Xu

Chin Med J (Engl) 2023 Aug 20; 136(16): 1949–1958. Published online 2023 Jul 17. doi: 10.1097/CM9.0000000000002786

PMCID:: PMC10431571

Abstract Article PDF–4.0M

Select item 103085353.

Polymorphisms of CARD9 Gene Predict Disease Progression and Renal Survival of Immunoglobulin A Nephropathy

Chunhong He, Dianchun Shi, Lin Guo, Zhong Zhong, Xue-Qing Yu, Ming Li

Kidney Blood Press Res. 2023 Jan-Dec; 48(1): 436–444. Published online 2023 Apr 14. doi: 10.1159/000530262

PMCID:: PMC10308535

Abstract Article

Select item 101080934.

CARD9 Expression Pattern, Gene Dosage, and Immunodeficiency Phenotype Revisited

Shubham Goel, Hye Sun Kuehn, Javier Chinen, Julie Niemela, Jennifer Stoddard, Daisuke Yamanaka, Mary Garofalo, Sophia Samir, Melanie Migaud, Vasileios Oikonomou, Thomas Fleisher, Anne Puel, Michail S. Lionakis, Sergio D. Rosenzweig

J Clin Immunol. Author manuscript; available in PMC 2023 Apr 17.

Published in final edited form as: J Clin Immunol. 2022 Feb; 42(2): 336–349. Published online 2021 Nov 17. doi: 10.1007/s10875-021-01173-6

PMCID:: PMC10108093

Abstract Article PDF–1.6M

Select item 99265515.

Genetic association of PRKCD and CARD9 polymorphisms with Vogt–Koyanagi–Harada disease in the Chinese Han population

Chunya Zhou, Shiya Cai, Yuhong Xie, Zhen Zeng, Jun Zhang, Guannan Su, Qiuying Wu, Xingsheng Ye, Qingfeng Cao, Peizeng Yang, Jianmin Hu

Hum Genomics. 2023; 17: 9. Published online 2023 Feb 13. doi: 10.1186/s40246-023-00459-7

PMCID:: PMC9926551

Abstract Article PDF–896K

Select item 98491416.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 96631597.

Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis

Rebecca A. Drummond, Jigar V. Desai, Amy P. Hsu, Vasileios Oikonomou, Donald C. Vinh, Joshua A. Acklin, Michael S. Abers, Magdalena A. Walkiewicz, Sarah L. Anzick, Muthulekha Swamydas, Simon Vautier, Mukil Natarajan, Andrew J. Oler, Daisuke Yamanaka, Katrin D. Mayer-Barber, Yoichiro Iwakura, David Bianchi, Brian Driscoll, Ken Hauck, Ahnika Kline, Nicholas S.P. Viall, Christa S. Zerbe, Elise M.N. Ferré, Monica M. Schmitt, Tom DiMaggio, Stefania Pittaluga, John A. Butman, Adrian M. Zelazny, Yvonne R. Shea, Cesar A. Arias, Cameron Ashbaugh, Maryam Mahmood, Zelalem Temesgen, Alexander G. Theofiles, Masayuki Nigo, Varsha Moudgal, Karen C. Bloch, Sean G. Kelly, M. Suzanne Whitworth, Ganesh Rao, Cindy J. Whitener, Neema Mafi, Juan Gea-Banacloche, Lawrence C. Kenyon, William R. Miller, Katia Boggian, Andrea Gilbert, Matthew Sincock, Alexandra F. Freeman, John E. Bennett, Rodrigo Hasbun, Constantinos M. Mikelis, Kyung J. Kwon-Chung, Yasmine Belkaid, Gordon D. Brown, Jean K. Lim, Douglas B. Kuhns, Steven M. Holland, Michail S. Lionakis

J Clin Invest. 2022 Nov 15; 132(22): e159348. Published online 2022 Nov 15. doi: 10.1172/JCI159348

PMCID:: PMC9663159

Abstract Article PDF–7.9M

Select item 93429588.

A nucleation barrier spring-loads the CBM signalosome for binary activation

Alejandro Rodriguez Gama, Tayla Miller, Jeffrey J Lange, Jay R Unruh, Randal Halfmann

eLife. 2022; 11: e79826. Published online 2022 Jun 21. doi: 10.7554/eLife.79826

PMCID:: PMC9342958

Abstract Article PDF–7.3M

Select item 87718579.

CARD9 Regulation and its Role in Cardiovascular Diseases

Haina Zhang, Yeling Wang, Hongbo Men, Wenqian Zhou, Shanshan Zhou, Quan Liu, Lu Cai

Int J Biol Sci. 2022; 18(3): 970–982. Published online 2022 Jan 1. doi: 10.7150/ijbs.65979

PMCID:: PMC8771857

Abstract Article PDF–860K

Select item 864054610.

The role and mechanism of CARD9 gene polymorphism in diseases

Changxue Ji, Zhiwen Yang, Xiaoming Zhong, Jindong Xia

Biomed J. 2021 Oct; 44(5): 560–566. Published online 2020 Dec 30. doi: 10.1016/j.bj.2020.12.006

PMCID:: PMC8640546

Abstract Article PDF–572K

Select item 847885611.

CARD9 mediates glucose-stimulated insulin secretion in pancreatic beta cells

Suhadinie Gamage, Mirabela Hali, Anjaneyulu Kowluru

Biochem Pharmacol. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Biochem Pharmacol. 2021 Oct; 192: 114670. Published online 2021 Jul 4. doi: 10.1016/j.bcp.2021.114670

PMCID:: PMC8478856

Abstract Article PDF–1.2M

Select item 831530812.

Inherited CARD9 deficiency in a patient with both: Exophiala spinifera and Aspergillus nomius severe infections

Laura Perez, Fernando Messina, Ricardo Negroni, Alicia Arechavala, Jacinta Bustamante, Matías Oleastro, Mélanie Migaud, Jean-Laurent Casanova, Anne Puel, Gabriela Santiso

J Clin Immunol. Author manuscript; available in PMC 2021 Jul 27.

Published in final edited form as: J Clin Immunol. 2020 Feb; 40(2): 359–366. Published online 2020 Jan 15. doi: 10.1007/s10875-019-00740-2

PMCID:: PMC8315308

Abstract Article PDF–948K

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 793685514.

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies

Itai Doron, Irina Leonardi, Xin V. Li, William D. Fiers, Alexa Semon, Meghan Bialt-DeCelie, Mélanie Migaud, Iris H. Gao, Woan-Yu Lin, Takato Kusakabe, Anne Puel, Iliyan D. Iliev

Cell. Author manuscript; available in PMC 2022 Feb 18.

Published in final edited form as: Cell. 2021 Feb 18; 184(4): 1017–1031.e14. Published online 2021 Feb 5. doi: 10.1016/j.cell.2021.01.016

PMCID:: PMC7936855

Abstract Article PDF–3.1M

Select item 775883615.

USP15 deubiquitinates CARD9 to downregulate C-type lectin receptor-mediated signaling

Wenting Xu, Jason S. Rush, Daniel B. Graham, Zhifang Cao, Ramnik J. Xavier

Immunohorizons. Author manuscript; available in PMC 2020 Dec 24.

Published in final edited form as: Immunohorizons. 2020 Oct 22; 4(10): 670–678. Published online 2020 Oct 22. doi: 10.4049/immunohorizons.2000036

PMCID:: PMC7758836

Abstract Article PDF–801K

Select item 737385216.

Caspase Recruitment Domain Containing Protein 9 Suppresses Non-Small Cell Lung Cancer Proliferation and Invasion via Inhibiting MAPK/p38 Pathway

Linyue Pan, Yuting Tan, Bin Wang, Wenjia Qiu, Yulei Yin, Haiyan Ge, Huili Zhu

Cancer Res Treat. 2020 Jul; 52(3): 867–885. Published online 2020 Mar 11. doi: 10.4143/crt.2019.606

PMCID:: PMC7373852

Abstract Article PDF–5.3M

Select item 732206717.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 716998318.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 674264619.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 662426720.

Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation

Michael J. Holliday, Axel Witt, Alejandro Rodríguez Gama, Benjamin T. Walters, Christopher P. Arthur, Randal Halfmann, Alexis Rohou, Erin C. Dueber, Wayne J. Fairbrother

Nat Commun. 2019; 10: 3070. Published online 2019 Jul 11. doi: 10.1038/s41467-019-10953-z

PMCID:: PMC6624267

Abstract Article PDF–5.4M

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