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Select item 111478421.

Central nervous system embryonal tumors with EWSR1-PLAGL1 rearrangements reclassified as INI-1 deficient tumors at relapse

Kevin J. Bielamowicz, Mary Beth Littrell, Gregory W. Albert, Lora S. Parker, Sateesh Jayappa, Kenneth Aldape, Murat Gokden

J Neurooncol. 2024; 168(2): 367–373. Published online 2024 Apr 19. doi: 10.1007/s11060-024-04667-6

PMCID:: PMC11147842

Abstract Article PDF–1.2M

Select item 109983162.

CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas

Arnault Tauziède-Espariat, Yvan Nicaise, Philipp Sievers, Felix Sahm, Andreas von Deimling, Delphine Guillemot, Gaëlle Pierron, Mathilde Duchesne, Myriam Edjlali, Volodia Dangouloff-Ros, Nathalie Boddaert, Alexandre Roux, Edouard Dezamis, Lauren Hasty, Benoît Lhermitte, Edouard Hirsch, Maria Paola Valenti Hirsch, François-Daniel Ardellier, Mélodie-Anne Karnoub, Marie Csanyi, Claude-Alain Maurage, Karima Mokhtari, Franck Bielle, Valérie Rigau, Thomas Roujeau, Marine Abad, Sébastien Klein, Michèle Bernier, Catherine Horodyckid, Clovis Adam, Petter Brandal, Pitt Niehusmann, Quentin Vannod-Michel, Corentin Provost, Nicolas Menjot de Champfleur, Lucia Nichelli, Alice Métais, Cassandra Mariet, Fabrice Chrétien, Thomas Blauwblomme, Kévin Beccaria, Johan Pallud, Stéphanie Puget, Emmanuelle Uro-Coste, Pascale Varlet, RENOCLIP-LOC

Acta Neuropathol Commun. 2024; 12: 55. Published online 2024 Apr 5. doi: 10.1186/s40478-023-01695-7

PMCID:: PMC10998316

Abstract Article PDF–2.8M

Select item 98117253.

PLAGL1 is associated with prognosis and cell proliferation in pancreatic adenocarcinoma

Xing Liang, Zhiping Fu, Liang Tang, Minghui Zheng, Danlei Chen, Anan Liu, Ligang Shi, Linhua Yang, Chenghao Shao, Xiaoqiang Dong

BMC Gastroenterol. 2023; 23: 2. Published online 2023 Jan 4. doi: 10.1186/s12876-022-02609-y

PMCID:: PMC9811725

Abstract Article PDF–2.6M

Select item 98074914.

Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

Michaela-Kristina Keck, Martin Sill, Andrea Wittmann, Piyush Joshi, Damian Stichel, Pengbo Beck, Konstantin Okonechnikow, Philipp Sievers, Annika K. Wefers, Federico Roncaroli, Shivaram Avula, Martin G. McCabe, James T. Hayden, Pieter Wesseling, Ingrid Øra, Monica Nistér, Mariëtte E. G. Kranendonk, Bastiaan B. J. Tops, Michal Zapotocky, Josef Zamecnik, Alexandre Vasiljevic, Tanguy Fenouil, David Meyronet, Katja von Hoff, Ulrich Schüller, Hugues Loiseau, Dominique Figarella-Branger, Christof M. Kramm, Dominik Sturm, David Scheie, Tuomas Rauramaa, Jouni Pesola, Johannes Gojo, Christine Haberler, Sebastian Brandner, Tom Jacques, Alexandra Sexton Oates, Richard Saffery, Ewa Koscielniak, Suzanne J. Baker, Stephen Yip, Matija Snuderl, Nasir Ud Din, David Samuel, Kathrin Schramm, Mirjam Blattner-Johnson, Florian Selt, Jonas Ecker, Till Milde, Andreas von Deimling, Andrey Korshunov, Arie Perry, Stefan M. Pfister, Felix Sahm, David A. Solomon, David T. W. Jones

Acta Neuropathol. 2023; 145(1): 49–69. Published online 2022 Nov 27. doi: 10.1007/s00401-022-02516-2

Correction in:: Acta Neuropathol. 2023; 145(4): 511–514.

PMCID:: PMC9807491

Abstract Article PDF–10M

Select item 91197365.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 85008956.

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

Philipp Sievers, Sophie C. Henneken, Christina Blume, Martin Sill, Daniel Schrimpf, Damian Stichel, Konstantin Okonechnikov, David E. Reuss, Julia Benzel, Kendra K. Maaß, Marcel Kool, Dominik Sturm, Tuyu Zheng, David R. Ghasemi, Patricia Kohlhof-Meinecke, Ofelia Cruz, Mariona Suñol, Cinzia Lavarino, Viktoria Ruf, Henning B. Boldt, Mélanie Pagès, Celso Pouget, Leonille Schweizer, Mariëtte E. G. Kranendonk, Noreen Akhtar, Stephanie Bunkowski, Christine Stadelmann , Ulrich Schüller, Wolf C. Mueller, Hildegard Dohmen, Till Acker, Patrick N. Harter, Christian Mawrin, Rudi Beschorner, Sebastian Brandner, Matija Snuderl, Zied Abdullaev, Kenneth Aldape, Mark R. Gilbert, Terri S. Armstrong, David W. Ellison, David Capper, Koichi Ichimura, Guido Reifenberger, Richard G. Grundy, Nada Jabado, Lenka Krskova, Michal Zapotocky, Ales Vicha, Pascale Varlet, Pieter Wesseling, Stefan Rutkowski, Andrey Korshunov, Wolfgang Wick, Stefan M. Pfister, David T. W. Jones, Andreas von Deimling, Kristian W. Pajtler, Felix Sahm

Acta Neuropathol. 2021; 142(5): 827–839. Published online 2021 Aug 5. doi: 10.1007/s00401-021-02356-6

PMCID:: PMC8500895

Abstract Article PDF–4.2M

Select item 76641917.

Transcription Factor PLAGL1 Is Associated with Angiogenic Gene Expression in the Placenta

Rebekah R. Starks, Rabab Abu Alhasan, Haninder Kaur, Kathleen A. Pennington, Laura C. Schulz, Geetu Tuteja

Int J Mol Sci. 2020 Nov; 21(21): 8317. Published online 2020 Nov 6. doi: 10.3390/ijms21218317

PMCID:: PMC7664191

Abstract Article PDF–3.9M

Select item 75203158.

Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations

Xiaolei Zhao, Shaoyan Chang, Xinli Liu, Shuangxing Wang, Yueran Zhang, Xiaolin Lu, Ting Zhang, Hui Zhang, Li Wang

J Cell Mol Med. 2020 Sep; 24(17): 9898–9907. Published online 2020 Jul 21. doi: 10.1111/jcmm.15584

PMCID:: PMC7520315

Abstract Article PDF–908K

Select item 73673069.

Gene expression profiling identifies the role of Zac1 in cervical cancer metastasis

Hui-Chen Su, Sheng-Cheng Wu, Li-Chen Yen, Li-Kang Chiao, Jehng-Kang Wang, Yi-Lin Chiu, Ching-Liang Ho, Shih-Ming Huang

Sci Rep. 2020; 10: 11837. Published online 2020 Jul 16. doi: 10.1038/s41598-020-68835-0

PMCID:: PMC7367306

Abstract Article PDF–4.3M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 573770011.

Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

Annie Varrault, Christelle Dantec, Anne Le Digarcher, Laëtitia Chotard, Benoit Bilanges, Hugues Parrinello, Emeric Dubois, Stéphanie Rialle, Dany Severac, Tristan Bouschet, Laurent Journot

Nucleic Acids Res. 2017 Oct 13; 45(18): 10466–10480. Published online 2017 Jul 29. doi: 10.1093/nar/gkx672

PMCID:: PMC5737700

Abstract Article PDF–3.3M

Select item 567858112.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 563060013.

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism

Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell

Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8

PMCID:: PMC5630600

Abstract Article PDF–2.3M

Select item 561981514.

A tissue-specific promoter derived from a SINE retrotransposon drives biallelic expression of PLAGL1 in human lymphocytes

Claire E. L. Smith, Alexia Alexandraki, Sarah F. Cordery, Rekha Parmar, David T. Bonthron, Elizabeth M. A. Valleley

PLoS One. 2017; 12(9): e0185678. Published online 2017 Sep 28. doi: 10.1371/journal.pone.0185678

PMCID:: PMC5619815

Abstract Article PDF–4.4M

Select item 433478515.

Altered expression of the imprinted transcription factor PLAGL1 deregulates a network of genes in the human IUGR placenta

Isabel Iglesias-Platas, Alex Martin-Trujillo, Paolo Petazzi, Amy Guillaumet-Adkins, Manel Esteller, David Monk

Hum Mol Genet. 2014 Dec 1; 23(23): 6275–6285. Published online 2014 Jul 3. doi: 10.1093/hmg/ddu347

PMCID:: PMC4334785

Abstract Article PDF–583K

Select item 414681616.

Promoter hypermethylation of CDH1, FHIT, MTAP and PLAGL1 in gastric adenocarcinoma in individuals from Northern Brazil

Mariana Ferreira Leal, Eleonidas Moura Lima, Patrícia Natália Oliveira Silva, Paulo Pimentel Assumpção, Danielle Queiroz Calcagno, Spencer Luiz Marques Payão, Rommel Rodríguez Burbano, Marília de Arruda Cardoso Smith

World J Gastroenterol. 2007 May 14; 13(18): 2568–2574. Published online 2007 May 14. doi: 10.3748/wjg.v13.i18.2568

PMCID:: PMC4146816

Abstract Article PDF–848K

Select item 405345217.

Degree of methylation of ZAC1 (PLAGL1) is associated with prenatal and post-natal growth in healthy infants of the EDEN mother child cohort

Salah Azzi, Theo CJ Sas, Yves Koudou, Yves Le Bouc, Jean-Claude Souberbielle, Patricia Dargent-Molina, Irène Netchine, Marie-Aline Charles

Epigenetics. 2014 Mar 1; 9(3): 338–345. Published online 2013 Dec 6. doi: 10.4161/epi.27387

PMCID:: PMC4053452

Abstract Article PDF–768K

Select item 382997218.

Prognostic Value of PLAGL1-Specific CpG Site Methylation in Soft-Tissue Sarcomas

Anne-Lise Peille, Veronique Brouste, Audrey Kauffmann, Pauline Lagarde, Valerie Le Morvan, Jean-Michel Coindre, Frederic Chibon, Laurence Bresson-Bepoldin

PLoS One. 2013; 8(11): e80741. Published online 2013 Nov 15. doi: 10.1371/journal.pone.0080741

PMCID:: PMC3829972

Abstract Article PDF–1.3M

Select item 378872319.

ZAC1 and SSTR2 Are Downregulated in Non-Functioning Pituitary Adenomas but Not in somatotropinomas

Leonardo Vieria Neto, Luiz Eduardo Wildemberg, Leandro Machado Colli, Leandro Kasuki, Nelma Veronica Marques, Aline Barbosa Moraes, Emerson L. Gasparetto, Christina Maeda Takiya, Margaret Castro, Mônica Roberto Gadelha

PLoS One. 2013; 8(10): e77406. Published online 2013 Oct 2. doi: 10.1371/journal.pone.0077406

Correction in:: PLoS One. 2013; 8(10): 10.1371/annotation/c55f4d48-d393-4ff5-b363-c9fc85bfbd93.

PMCID:: PMC3788723

Abstract Article PDF–327K

Select item 358276920.

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression

Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross

Mol Cell. Author manuscript; available in PMC 2014 Feb 21.

Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012

PMCID:: PMC3582769

Abstract Article PDF–4.5M

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