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Items: 1 to 20 of 30

1.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M
2.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
3.
Variants in FAT1 and COL9A1 genes in male population with or without substance use to assess the risk factors for oral malignancy
Chia-Min Chung, Chung-Chieh Hung, Chien-Hung Lee, Chi-Pin Lee, Ka-Wo Lee, Mu-Kuan Chen, Kun-Tu Yeh, Ying-Chin Ko
PLoS One. 2019; 14(1): e0210901. Published online 2019 Jan 18. doi: 10.1371/journal.pone.0210901
PMCID:
PMC6338366
AbstractArticlePDF–611K
4.
Whole-genome sequencing reveals novel genes in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population
Chen Liang, Peng Wang, Xiao Liu, Chenlong Yang, Yunlong Ma, Lei Yong, Bin Zhu, Xiaoguang Liu, Zhongjun Liu
J Orthop Surg Res. 2018; 13: 324. Published online 2018 Dec 22. doi: 10.1186/s13018-018-1022-8
PMCID:
PMC6303868
AbstractArticlePDF–1.1M
5.
A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220
Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang
Cancer Res. Author manuscript; available in PMC 2018 Aug 15.
Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627
PMCID:
PMC5559306
AbstractArticlePDF–885K
6.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
7.
Structural insight for chain selection and stagger control in collagen
Sergei P. Boudko, Hans Peter Bächinger
Sci Rep. 2016; 6: 37831. Published online 2016 Nov 29. doi: 10.1038/srep37831
PMCID:
PMC5126661
AbstractArticlePDF–1.4M
8.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
9.
COL9A1 Gene Polymorphism Is Associated with Kashin-Beck Disease in a Northwest Chinese Han Population
Xiaowei Shi, Feng Zhang, Aili Lv, Yan Wen, Xiong Guo
PLoS One. 2015; 10(3): e0120365. Published online 2015 Mar 16. doi: 10.1371/journal.pone.0120365
PMCID:
PMC4361735
AbstractArticlePDF–514K
10.
Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver
Alexandra Naba, Karl R Clauser, Charles A Whittaker, Steven A Carr, Kenneth K Tanabe, Richard O Hynes
BMC Cancer. 2014; 14: 518. Published online 2014 Jul 18. doi: 10.1186/1471-2407-14-518
PMCID:
PMC4223627
AbstractArticlePDF–1.5M
11.
Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation
Kei Imagawa, María C de Andrés, Ko Hashimoto, Eiji Itoi, Miguel Otero, Helmtrud I Roach, Mary B Goldring, Richard O C Oreffo
Arthritis Rheumatol. 2014 Nov; 66(11): 3040–3051. Published online 2014 Oct 26. doi: 10.1002/art.38774
PMCID:
PMC4211984
AbstractArticlePDF–637K
12.
Type IX collagen gene mutations can result in multiple epiphyseal dysplasia that is associated with osteochondritis dissecans and a mild myopathy
Gail C Jackson, Dominique Marcus-Soekarman, Irene Stolte-Dijkstra, Aad Verrips, Jacqueline A Taylor, Michael D Briggs
Am J Med Genet A. 2010 Apr; 152A(4): 863–869. Published online 2012 Mar 26. doi: 10.1002/ajmg.a.33240
PMCID:
PMC3557369
AbstractArticlePDF–202K
13.
The NC2 Domain of Type IX Collagen Determines the Chain Register of the Triple Helix
Sergei P. Boudko, Hans Peter Bächinger
J Biol Chem. 2012 Dec 28; 287(53): 44536–44545. Published online 2012 Nov 6. doi: 10.1074/jbc.M112.417543
PMCID:
PMC3531767
AbstractArticlePDF–1.4M
14.
Type IX Collagen Interacts with Fibronectin Providing an Important Molecular Bridge in Articular Cartilage
Philippa Parsons, Sophie J. Gilbert, Anne Vaughan-Thomas, David A. Sorrell, Rebecca Notman, Mark Bishop, Anthony J. Hayes, Deborah J. Mason, Victor C. Duance
J Biol Chem. 2011 Oct 7; 286(40): 34986–34997. Published online 2011 Jul 15. doi: 10.1074/jbc.M111.238188
PMCID:
PMC3186408
AbstractArticlePDF–2.2M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
17.
The NC2 Domain of Collagen IX Provides Chain Selection and Heterotrimerization
Sergei P. Boudko, Keith D. Zientek, Jesse Vance, Jessica L. Hacker, Jürgen Engel, Hans Peter Bächinger
J Biol Chem. 2010 Jul 30; 285(31): 23721–23731. Published online 2010 May 27. doi: 10.1074/jbc.M110.128405
PMCID:
PMC2911272
AbstractArticlePDF–3.3M
18.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
19.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
20.
STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF RECOMBINANT MATRILIN-3 A-DOMAIN AND IMPLICATIONS FOR HUMAN GENETIC BONE DISEASES
Maryline Fresquet, Thomas A. Jowitt, Joni Ylöstalo, Paul Coffey, Roger S. Meadows, Leena Ala-Kokko, David J. Thornton, Michael D. Briggs
J Biol Chem. Author manuscript; available in PMC 2009 Apr 24.
Published in final edited form as: J Biol Chem. 2007 Nov 30; 282(48): 34634–34643. Published online 2007 Sep 18. doi: 10.1074/jbc.M705301200
PMCID:
PMC2673055
AbstractArticlePDF–1.3M

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