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Items: 1 to 20 of 74

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork
Abdul B Hayran, Nina B Liabakk, Per A Aas, Anna Kusnierczyk, Cathrine B Vågbø, Antonio Sarno, Tobias S Iveland, Konika Chawla, Astrid Zahn, Javier M Di Noia, Geir Slupphaug, Bodil Kavli
Nucleic Acids Res. 2024 Jan 25; 52(2): 784–800. Published online 2023 Nov 24. doi: 10.1093/nar/gkad1115
PMCID:
PMC10810282
ArticlePDF–2.0M
3.
SPIDR is required for homologous recombination during mammalian meiosis
Tao Huang, Xinyue Wu, Shiyu Wang, Ziyou Bao, Yanling Wan, Ziqi Wang, Mengjing Li, Xiaochen Yu, Yue Lv, Zhaojian Liu, Xiangfeng Chen, Wai-Yee Chan, Fei Gao, Gang Lu, Zi-Jiang Chen, Hongbin Liu
Nucleic Acids Res. 2023 May 8; 51(8): 3855–3868. Published online 2023 Mar 20. doi: 10.1093/nar/gkad154
PMCID:
PMC10164582
ArticlePDF–11M
4.
Loss of RPA1 Impairs Peripheral T Cell Homeostasis and Exacerbates Inflammatory Damage through Triggering T Cell Necroptosis
Jia Song, Xin Zhang, Yue Yin, Mengfan Guo, Xuyang Zhao, Likun Wang, Caixia Ren, Yuxin Yin, Xuehui Zhang, Xuliang Deng, Dan Lu
Adv Sci (Weinh) 2023 Apr; 10(11): 2206344. Published online 2023 Jan 31. doi: 10.1002/advs.202206344
PMCID:
PMC10104672
ArticlePDF–6.8M
5.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
ArticlePDF–3.5M
6.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
ArticlePDF–6.6M
7.
SIRT7 promotes chromosome synapsis during prophase I of female meiosis
Berta N. Vazquez, Cecilia S. Blengini, Yurdiana Hernandez, Lourdes Serrano, Karen Schindler
Chromosoma. Author manuscript; available in PMC 2021 Oct 6.
Published in final edited form as: Chromosoma. 2019 Sep; 128(3): 369–383. Published online 2019 Jun 29. doi: 10.1007/s00412-019-00713-9
PMCID:
PMC8494110
ArticlePDF–2.5M
8.
Retinal degeneration in mice and humans with neuronal ceroid lipofuscinosis type 8
Elyse M. Salpeter, Brian C. Leonard, Antonio J. Lopez, Christopher J. Murphy, Sara Thomasy, Denise M. Imai, Kristin Grimsrud, K. C. Kent Lloyd, Jiong Yan, Rossana Sanchez Russo, Suma P. Shankar, Ala Moshiri
Ann Transl Med. 2021 Aug; 9(15): 1274. doi: 10.21037/atm-20-4739
PMCID:
PMC8421982
ArticlePDF–4.4M
9.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
ArticlePDF–1.6M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
11.
A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1
Natalia Felipe-Medina, Sandrine Caburet, Fernando Sánchez-Sáez, Yazmine B Condezo, Dirk G de Rooij, Laura Gómez-H, Rodrigo Garcia-Valiente, Anne Laure Todeschini, Paloma Duque, Manuel Adolfo Sánchez-Martin, Stavit A Shalev, Elena Llano, Reiner A Veitia, Alberto M Pendás
eLife. 2020; 9: e56996. Published online 2020 Aug 26. doi: 10.7554/eLife.56996
PMCID:
PMC7498267
ArticlePDF–12M
12.
The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates
Anjali Gupta Hinch, Philipp W. Becker, Tao Li, Daniela Moralli, Gang Zhang, Clare Bycroft, Catherine Green, Scott Keeney, Qinghua Shi, Benjamin Davies, Peter Donnelly
Mol Cell. 2020 Aug 20; 79(4): 689–701.e10. doi: 10.1016/j.molcel.2020.06.015
PMCID:
PMC7447979
Article
13.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
ArticlePDF–2.0M
14.
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer
Lakshya Bajaj, Jaiprakash Sharma, Alberto di Ronza, Pengcheng Zhang, Aiden Eblimit, Rituraj Pal, Dany Roman, John R. Collette, Clarissa Booth, Kevin T. Chang, Richard N. Sifers, Sung Y. Jung, Jill M. Weimer, Rui Chen, Randy W. Schekman, Marco Sardiello
J Clin Invest. 2020 Aug 3; 130(8): 4118–4132. Published online 2020 Jun 29. doi: 10.1172/JCI130955
PMCID:
PMC7410054
ArticlePDF–8.5M
15.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
ArticlePDF–5.4M
16.
Apparent Loss and Hypertrophy of Interneurons in a Mouse Model of Neuronal Ceroid Lipofuscinosis: Evidence for Partial Response to Insulin-Like Growth Factor-1 Treatment
Jonathan D. Cooper, Anne Messer, Andrew K. Feng, Jane Chua-Couzens, William C. Mobley
J Neurosci. 1999 Apr 1; 19(7): 2556–2567. doi: 10.1523/JNEUROSCI.19-07-02556.1999
PMCID:
PMC6786069
ArticlePDF–997K
17.
Early and Selective Loss of Neuromuscular Synapse Subtypes with Low Sprouting Competence in Motoneuron Diseases
Dunja Frey, Corinna Schneider, Lan Xu, Jacques Borg, Will Spooren, Pico Caroni
J Neurosci. 2000 Apr 1; 20(7): 2534–2542. doi: 10.1523/JNEUROSCI.20-07-02534.2000
PMCID:
PMC6772256
ArticlePDF–1000K
18.
Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome
Qianting Zhang, Shu-Yan Ji, Kiran Busayavalasa, Jingchen Shao, Chao Yu
Nat Commun. 2019; 10: 3387. Published online 2019 Jul 29. doi: 10.1038/s41467-019-11346-y
PMCID:
PMC6662770
ArticlePDF–14M
19.
Dual functions for the ssDNA-binding protein RPA in meiotic recombination
Baolu Shi, Jiangyang Xue, Hao Yin, Rui Guo, Mengcheng Luo, Lan Ye, Qinghua Shi, Xiaoyan Huang, Mingxi Liu, Jiahao Sha, P. Jeremy Wang
PLoS Genet. 2019 Feb; 15(2): e1007952. Published online 2019 Feb 4. doi: 10.1371/journal.pgen.1007952
PMCID:
PMC6375638
ArticlePDF–4.8M
20.
A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination
Jingjing Zhang, Yasuhiro Fujiwara, Shohei Yamamoto, Hiroki Shibuya
Nat Commun. 2019; 10: 722. Published online 2019 Feb 13. doi: 10.1038/s41467-019-08676-2
Correction in:
Nat Commun. 2019; 10: 986.
PMCID:
PMC6374363
ArticlePDF–4.8M

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