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Select item 103938181.

Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity

Yaoling Shu, Nikhil Gumma, Faizule Hassan, Daniel A. Branch, Lisa A. Baer, Michael C. Ostrowski, Kristin I. Stanford, Kedryn K. Baskin, Kamal D. Mehta

J Biol Chem. 2023 Aug; 299(8): 104917. Published online 2023 Jun 12. doi: 10.1016/j.jbc.2023.104917

PMCID:: PMC10393818

Abstract Article PDF–2.0M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 95199793.

Loss of RPTPγ primes breast tissue for acid extrusion, promotes malignant transformation and results in early tumour recurrence and shortened survival

Rasmus A. Sloth, Trine V. Axelsen, Maria Sofia Espejo, Nicolai J. Toft, Ninna C. S. Voss, Mark Burton, Mads Thomassen, Pernille Vahl, Ebbe Boedtkjer

Br J Cancer. 2022 Oct 19; 127(7): 1226–1238. Published online 2022 Jul 11. doi: 10.1038/s41416-022-01911-6

PMCID:: PMC9519979

Abstract Article PDF–2.0M

Select item 85256384.

Role of hepatic PKCβ in nutritional regulation of hepatic glycogen synthesis

Yaoling Shu, Faizule Hassan, Michael C. Ostrowski, Kamal D. Mehta

JCI Insight. 2021 Oct 8; 6(19): e149023. Published online 2021 Oct 8. doi: 10.1172/jci.insight.149023

PMCID:: PMC8525638

Abstract Article PDF–1.1M

Select item 84129975.

Presynaptic Short-Term Plasticity Persists in the Absence of PKC Phosphorylation of Munc18-1

Chih-Chieh Wang, Christopher Weyrer, Diasynou Fioravante, Pascal S. Kaeser, Wade G. Regehr

J Neurosci. 2021 Sep 1; 41(35): 7329–7339. doi: 10.1523/JNEUROSCI.0347-21.2021

PMCID:: PMC8412997

Abstract Article PDF–2.4M

Select item 80677296.

Signalling Pathways Mediating the Effects of CD40-Activated CD40L Reverse Signalling on Inhibitory Medium Spiny Neuron Neurite Growth

Paulina Carriba, Alun M. Davies

Cells. 2021 Apr; 10(4): 829. Published online 2021 Apr 7. doi: 10.3390/cells10040829

PMCID:: PMC8067729

Abstract Article PDF–6.3M

Select item 79610317.

All-trans retinoic acid and protein kinase C α/β1 inhibitor combined treatment targets cancer stem cells and impairs breast tumor progression

Damian Emilio Berardi, Lizeth Ariza Bareño, Natalia Amigo, Luciana Cañonero, Maria de las Nieves Pelagatti, Andrea Nora Motter, María Agustina Taruselli, María Inés Díaz Bessone, Stefano Martin Cirigliano, Alexis Edelstein, María Giselle Peters, Miriam Diament, Alejandro Jorge Urtreger, Laura Beatriz Todaro

Sci Rep. 2021; 11: 6044. Published online 2021 Mar 15. doi: 10.1038/s41598-021-85344-w

PMCID:: PMC7961031

Abstract Article PDF–5.8M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77859569.

Hepatocyte-specific PKCβ deficiency protects against high-fat diet-induced nonalcoholic hepatic steatosis

Yaoling Shu, Faizule Hassan, Vincenzo Coppola, Kedryn K. Baskin, Xianlin Han, Neil K. Mehta, Michael C. Ostrowski, Kamal D. Mehta

Mol Metab. 2021 Feb; 44: 101133. Published online 2020 Nov 30. doi: 10.1016/j.molmet.2020.101133

PMCID:: PMC7785956

Abstract Article PDF–2.1M

Select item 740314610.

A novel transgenic mouse strain expressing PKCβII demonstrates expansion of B1 and marginal zone B cell populations

Ali A. Azar, Alison M. Michie, Anuradha Tarafdar, Natasha Malik, Geetha K. Menon, Kathleen J. Till, Nikolina Vlatković, Joseph R. Slupsky

Sci Rep. 2020; 10: 13156. Published online 2020 Aug 4. doi: 10.1038/s41598-020-70191-y

PMCID:: PMC7403146

Abstract Article PDF–4.3M

Select item 711636511.

Stromal cell Protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance

Eugene Park, Jingyu Chen, Andrew Moore, Maurizio Mangolini, Antonella Santoro, Joseph R. Boyd, Hilde Schjerven, Veronika Ecker, Maike Buchner, James C. Williamson, Paul J. Lehner, Luca Gasparoli, Owen Williams, Johannes Bloehdorn, Stephan Stilgenbauer, Michael Leitges, Alexander Egle, Marc Schmidt-Supprian, Seth Frietze, Ingo Ringshausen

Sci Transl Med. Author manuscript; available in PMC 2020 Nov 17.

Published in final edited form as: Sci Transl Med. 2020 Jan 15; 12(526): eaax9340. Published online 2020 Jan 15. doi: 10.1126/scitranslmed.aax9340

PMCID:: PMC7116365

Abstract Article PDF–3.1M

Select item 677261112.

A Role for the β Isoform of Protein Kinase C in Fear Conditioning

Edwin J. Weeber, Coleen M. Atkins, Joel C. Selcher, Andrew W. Varga, Banafsheh Mirnikjoo, Richard Paylor, Michael Leitges, J. David Sweatt

J Neurosci. 2000 Aug 15; 20(16): 5906–5914. doi: 10.1523/JNEUROSCI.20-16-05906.2000

PMCID:: PMC6772611

Abstract Article PDF–261K

Select item 647201813.

Decreased Protein Kinase C-β Type II Associated with the Prominent Endotoxin Exhaustion in the Macrophage of FcGRIIb−/− Lupus Prone Mice is Revealed by Phosphoproteomic Analysis

Thunnicha Ondee, Thiranut Jaroonwitchawan, Trairak Pisitkun, Joseph Gillen, Aleksandra Nita-Lazar, Asada Leelahavanichkul, Poorichaya Somparn

Int J Mol Sci. 2019 Mar; 20(6): 1354. Published online 2019 Mar 18. doi: 10.3390/ijms20061354

PMCID:: PMC6472018

Abstract Article PDF–2.7M

Select item 642249814.

PKCβ1 regulates meiotic cell cycle in mouse oocyte

Zi-Yun Yi, Qiu-Xia Liang, Tie-Gang Meng, Jian Li, Ming-Zhe Dong, Yi Hou, Ying-Chun Ouyang, Chun-Hui Zhang, Heide Schatten, Qing-Yuan Sun, Jie Qiao, Wei-Ping Qian

Cell Cycle. 2019; 18(4): 395–412. Published online 2019 Feb 7. doi: 10.1080/15384101.2018.1564492

PMCID:: PMC6422498

Abstract Article PDF–2.7M

Select item 637198215.

PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5

Thomas B. Schaffer, Jaclyn E. Smith, Emily K. Cook, Thao Phan, Seth S. Margolis

Cell Rep. Author manuscript; available in PMC 2019 Feb 12.

Published in final edited form as: Cell Rep. 2018 Nov 27; 25(9): 2470–2483.e8. doi: 10.1016/j.celrep.2018.11.005

PMCID:: PMC6371982

Abstract Article PDF–2.4M

Select item 631390016.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

Select item 627917917.

PKC-β activation inhibits IL-18-binding protein causing endothelial dysfunction and diabetic atherosclerosis

Marie-Claude Durpès, Catherine Morin, Judith Paquin-Veillet, Raphaël Beland, Martin Paré, Marie-Odile Guimond, Mark Rekhter, George L. King, Pedro Geraldes

Cardiovasc Res. 2015 May 1; 106(2): 303–313. Published online 2015 Mar 25. doi: 10.1093/cvr/cvv107

PMCID:: PMC6279179

Abstract Article PDF–952K

Select item 610074318.

PKCα integrates spatiotemporally distinct Ca²⁺ and autocrine BDNF signaling to facilitate synaptic plasticity

Lesley A Colgan, Mo Hu, Jaime A Misler, Paula Parra-Bueno, Corey M Moran, Michael Leitges, Ryohei Yasuda

Nat Neurosci. Author manuscript; available in PMC 2019 Jan 16.

Published in final edited form as: Nat Neurosci. 2018 Aug; 21(8): 1027–1037. Published online 2018 Jul 16. doi: 10.1038/s41593-018-0184-3

PMCID:: PMC6100743

Abstract Article PDF–3.2M

Select item 587889419.

Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice

Jiayin Zheng, Yue Wang, Song Han, Yanlin Luo, Xiuli Sun, Ning Zhu, Li Zhao, Junfa Li

J Diabetes Res. 2018; 2018: 8431249. Published online 2018 Mar 18. doi: 10.1155/2018/8431249

PMCID:: PMC5878894

Abstract Article PDF–1.7M

Select item 587596020.

Protein Kinase 2β Is Expressed in Neural Crest-Derived Urinary Pacemaker Cells and Required for Pyeloureteric Contraction

Samir M. Iskander, Meghan M. Feeney, Kirby Yee, Norman D. Rosenblum

J Am Soc Nephrol. 2018 Apr; 29(4): 1198–1209. Published online 2018 Feb 7. doi: 10.1681/ASN.2017090951

PMCID:: PMC5875960

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