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Items: 1 to 20 of 48

1.
Transcriptional repression of the ectodomain sheddase ADAM10 by TBX2 and potential implication for Alzheimer’s disease
Sven Reinhardt, Florian Schuck, Nicolai Stoye, Tobias Hartmann, Marcus O. W. Grimm, Gert Pflugfelder, Kristina Endres
Cell Mol Life Sci. 2019 Mar; 76(5): 1005–1025. Published online 2019 Jan 1. doi: 10.1007/s00018-018-2998-2
PMCID:
PMC11105458
AbstractArticlePDF–2.6M
2.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
3.
T‐box transcription factor 2 mediates antitumor immune response in cutaneous squamous cell carcinoma by regulating the expression of programmed death ligand 1
Xu Wang, Zhi Li, Yadi Sun
Skin Res Technol. 2023 Jan; 29(1): e13254. Published online 2022 Dec 7. doi: 10.1111/srt.13254
PMCID:
PMC9838745
AbstractArticlePDF–1.2M
4.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
5.
Clinical and Genetic Characteristics of Preeclampsia
Golovchenko O. V, Abramova M. Y, Orlova V. S, Batlutskaya I. V, Sorokina I. N
Arch Razi Inst. 2022 Feb; 77(1): 293–299. Published online 2022 Feb 28. doi: 10.22092/ARI.2021.356481.1852
PMCID:
PMC9288621
AbstractArticlePDF–572K
6.
TBX2, a Novel Regulator of Labour
Febilla Fernando, Geertruda J.M. Veenboer, Martijn A. Oudijk, Marlies A.M. Kampman, Karst Y. Heida, Louise J.M. Lagendijk, Joris A.M. van der Post, Aldo Jongejan, Gijs B. Afink, Carrie Ris-Stalpers
Medicina (Kaunas) 2021 Jun; 57(6): 515. Published online 2021 May 21. doi: 10.3390/medicina57060515
PMCID:
PMC8224059
AbstractArticlePDF–5.3M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
11.
The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei
Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz
Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2
PMCID:
PMC6746822
AbstractArticlePDF–2.0M
12.
TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells
N. T. Crawford, A.J. McIntyre, A. McCormick, Z. C. D'Costa, N. E. Buckley, P. B. Mullan
Oncogene. Author manuscript; available in PMC 2019 Aug 2.
Published in final edited form as: Oncogene. 2019 Jun 28; 38(31): 5971–5986. Published online 2019 Jun 28. doi: 10.1038/s41388-019-0853-z
PMCID:
PMC6677575
AbstractArticlePDF–2.3M
13.
A regulatory variant in TBX2 promoter is related to the decreased susceptibility of congenital heart disease in the Han Chinese population
Ran‐ran Zhang, Ke Cai, Lian Liu, Qian Yang, Ping Zhang, Yong‐hao Gui, Feng Wang
Mol Genet Genomic Med. 2019 Feb; 7(2): e00530. Published online 2018 Dec 7. doi: 10.1002/mgg3.530
PMCID:
PMC6393683
AbstractArticlePDF–515K
14.
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
Bieke Decaesteker, Geertrui Denecker, Christophe Van Neste, Emmy M. Dolman, Wouter Van Loocke, Moritz Gartlgruber, Carolina Nunes, Fanny De Vloed, Pauline Depuydt, Karen Verboom, Dries Rombaut, Siebe Loontiens, Jolien De Wyn, Waleed M. Kholosy, Bianca Koopmans, Anke H. W. Essing, Carl Herrmann, Daniel Dreidax, Kaat Durinck, Dieter Deforce, Filip Van Nieuwerburgh, Anton Henssen, Rogier Versteeg, Valentina Boeva, Gudrun Schleiermacher, Johan van Nes, Pieter Mestdagh, Suzanne Vanhauwaert, Johannes H. Schulte, Frank Westermann, Jan J. Molenaar, Katleen De Preter, Frank Speleman
Nat Commun. 2018; 9: 4866. Published online 2018 Nov 19. doi: 10.1038/s41467-018-06699-9
PMCID:
PMC6242972
AbstractArticlePDF–13M
15.
Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing
Huilin Xie, Erge Zhang, Nanchao Hong, Qihua Fu, Fen Li, Sun Chen, Yu Yu, Kun Sun
Hum Genomics. 2018; 12: 44. Published online 2018 Sep 17. doi: 10.1186/s40246-018-0176-0
PMCID:
PMC6142335
AbstractArticlePDF–2.5M
16.
The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin
Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342
PMCID:
PMC6076439
AbstractArticlePDF–2.5M
17.
Functional variants in TBX2 are associated with a syndromic cardiovascular and skeletal developmental disorder
Ning Liu, Kelly Schoch, Xi Luo, Loren D M Pena, Venkata Hemanjani Bhavana, Mary K Kukolich, Sarah Stringer, Zöe Powis, Kelly Radtke, Cameron Mroske, Kristen L Deak, Marie T McDonald, Allyn McConkie-Rosell, M Louise Markert, Peter G Kranz, Nicholas Stong, Anna C Need, David Bick, Michelle D Amaral, Elizabeth A Worthey, Shawn Levy, Undiagnosed Diseases Network (UDN), Michael F Wangler, Hugo J Bellen, Vandana Shashi, Shinya Yamamoto
Hum Mol Genet. 2018 Jul 15; 27(14): 2454–2465. Published online 2018 May 2. doi: 10.1093/hmg/ddy146
PMCID:
PMC6030957
AbstractArticlePDF–849K
18.
Effect of silencing the T-Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells
Wen-Liang Du, Qian Fang, Yue Chen, Jing-Wei Teng, Yong-Shuang Xiao, Ping Xie, Bo Jin, Jun-Qi Wang
Mol Med Rep. 2017 Nov; 16(5): 6050–6058. Published online 2017 Aug 24. doi: 10.3892/mmr.2017.7361
PMCID:
PMC5865808
AbstractArticlePDF–1.8M
19.
Multiple gene variations contributed to congenital heart disease via GATA family transcriptional regulation
Yanyan Qian, Deyong Xiao, Xiao Guo, Hongbo Chen, Lili Hao, Xiaojing Ma, Guoying Huang, Duan Ma, Huijun Wang
J Transl Med. 2017; 15: 69. Published online 2017 Apr 3. doi: 10.1186/s12967-017-1173-0
PMCID:
PMC5379520
AbstractArticlePDF–3.8M
20.
Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2
Damiano Fantini, Shuo Huang, John M. Asara, Srilata Bagchi, Pradip Raychaudhuri
Mol Biol Cell. 2017 Jan 1; 28(1): 192–200. doi: 10.1091/mbc.E16-08-0573
PMCID:
PMC5221623
AbstractArticlePDF–1.7M

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