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Select item 114166361.

The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners

Fabian Schwerdtfeger, Ilse Hoogvliet, Sjoerd van Deventer, Annemiek B. van Spriel

J Biol Chem. 2024 Sep; 300(9): 107685. Published online 2024 Aug 17. doi: 10.1016/j.jbc.2024.107685

PMCID:: PMC11416636

Abstract Article PDF–2.0M

Select item 113893982.

CD81 fusion alters SARS-CoV-2 Spike trafficking

Allaura S. Cone, Yijun Zhou, Ryan P. McNamara, Anthony. B. Eason, Gabriel F. Arias, Justin T. Landis, Kyle W. Shifflett, Meredith G. Chambers, Runjie Yuan, Smaranda Willcox, Jack D. Griffith, Dirk P. Dittmer

mBio. 2024 Sep; 15(9): e01922-24. Published online 2024 Aug 14. doi: 10.1128/mbio.01922-24

PMCID:: PMC11389398

Abstract Article PDF–4.8M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 109547804.

CD81 and CD82 expressing tumor-infiltrating lymphocytes in the NSCLC tumor microenvironment play a crucial role in T-cell activation and cytokine production

Kwangmin Na, Seul Lee, Dong Kwon Kim, Young Seob Kim, Joon Yeon Hwang, Seong-san Kang, Sujeong Baek, Chai Young Lee, Seung Min Yang, Yu Jin Han, Mi hyun Kim, Heekyung Han, Youngtaek Kim, Jae Hwan Kim, Seunghyun Jeon, Youngseon Byeon, Jii Bum Lee, Sun Min Lim, Min Hee Hong, Kyoung-Ho Pyo, Byoung Chul Cho

Front Immunol. 2024; 15: 1336246. Published online 2024 Mar 7. doi: 10.3389/fimmu.2024.1336246

PMCID:: PMC10954780

Abstract Article PDF–7.3M

Select item 106176735.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 105431546.

Small extracellular vesicles have distinct CD81 and CD9 tetraspanin expression profiles in plasma from rheumatoid arthritis patients

Anne Rydland, Fatima Heinicke, Siri T. Flåm, Maria D. Mjaavatten, Benedicte A. Lie

Clin Exp Med. 2023; 23(6): 2867–2875. Published online 2023 Feb 24. doi: 10.1007/s10238-023-01024-1

PMCID:: PMC10543154

Abstract Article PDF–3.4M

Select item 103906637.

Differential proteomics argues against a general role for CD9, CD81 or CD63 in the sorting of proteins into extracellular vesicles

Yé Fan, Cédric Pionneau, Federico Cocozza, Pierre‐Yves Boëlle, Solenne Chardonnet, Stéphanie Charrin, Clotilde Théry, Pascale Zimmermann, Eric Rubinstein

J Extracell Vesicles. 2023 Aug; 12(8): 12352. Published online 2023 Jul 31. doi: 10.1002/jev2.12352

PMCID:: PMC10390663

Abstract Article PDF–2.4M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100339379.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 993768810.

Zinc finger protein-like 1 is a novel neuroendocrine biomarker for prostate cancer

Neshat Masud, Afaf Aldahish, Kenneth A. Iczkowski, Ajay Kale, Girish V. Shah

Int J Oncol. 2023 Mar; 62(3): 38. Published online 2023 Feb 6. doi: 10.3892/ijo.2023.5486

PMCID:: PMC9937688

Abstract Article PDF–9.5M

Select item 953018611.

Circulating CD81-expressing extracellular vesicles as biomarkers of response for immune-checkpoint inhibitors in advanced NSCLC

Diego Signorelli, Patrizia Ghidotti, Claudia Proto, Marta Brambilla, Alessandro De Toma, Roberto Ferrara, Giulia Galli, Monica Ganzinelli, Giuseppe Lo Russo, Arsela Prelaj, Mario Occhipinti, Giuseppe Viscardi, Valentina Capizzuto, Francesca Pontis, Ilaria Petraroia, Anna Maria Ferretti, Mario Paolo Colombo, Valter Torri, Gabriella Sozzi, Marina Chiara Garassino, Elena Jachetti, Orazio Fortunato

Front Immunol. 2022; 13: 987639. Published online 2022 Sep 20. doi: 10.3389/fimmu.2022.987639

PMCID:: PMC9530186

Abstract Article PDF–4.1M

Select item 931431512.

A secretory form of Parkin‐independent mitophagy contributes to the repertoire of extracellular vesicles released into the tumour interstitial fluid in vivo

Marissa Howard, James Erickson, Zachary Cuba, Shawn Kim, Weidong Zhou, Purva Gade, Rachel Carter, Kelsey Mitchell, Heather Branscome, Daivik Siddhi, Fatimah Alanazi, Yuriy Kim, Robyn P. Araujo, Amanda Haymond, Alessandra Luchini, Fatah Kashanchi, Lance A. Liotta

J Extracell Vesicles. 2022 Jul; 11(7): e12244. Published online 2022 Jul 25. doi: 10.1002/jev2.12244

PMCID:: PMC9314315

Abstract Article PDF–3.4M

Select item 927928513.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 923908514.

The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication

Lisa Lasswitz, Francisco J. Zapatero-Belinchón, Rebecca Moeller, Kirsten Hülskötter, Timothée Laurent, Lars-Anders Carlson, Christine Goffinet, Graham Simmons, Wolfgang Baumgärtner, Gisa Gerold

mBio. 2022 May-Jun; 13(3): e00731-22. Published online 2022 May 25. doi: 10.1128/mbio.00731-22

PMCID:: PMC9239085

Abstract Article PDF–3.1M

Select item 914448015.

Methylene Blue Is a Nonspecific Protein–Protein Interaction Inhibitor with Potential for Repurposing as an Antiviral for COVID-19

Sung-Ting Chuang, Henrietta Papp, Anett Kuczmog, Rebecca Eells, Jose M. Condor Capcha, Lina A. Shehadeh, Ferenc Jakab, Peter Buchwald

Pharmaceuticals (Basel) 2022 May; 15(5): 621. Published online 2022 May 18. doi: 10.3390/ph15050621

PMCID:: PMC9144480

Abstract Article PDF–2.5M

Select item 911973616.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 861691517.

Pax5 mediates the transcriptional activation of the CD81 gene

Kohei Hosokawa, Hanako Ishimaru, Tadashi Watanabe, Masahiro Fujimuro

Sci Rep. 2021; 11: 22919. Published online 2021 Nov 25. doi: 10.1038/s41598-021-02082-9

PMCID:: PMC8616915

Abstract Article PDF–2.7M

Select item 854261418.

STRUCTURAL INSIGHTS INTO HEPATITIS C VIRUS RECEPTOR BINDING AND ENTRY

Ashish Kumar, Reafa A. Hossain, Samantha A. Yost, Wei Bu, Yuanyuan Wang, Altaira D. Dearborn, Arash Grakoui, Jeffrey I. Cohen, Joseph Marcotrigiano

Nature. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Nature. 2021 Oct; 598(7881): 521–525. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03913-5

PMCID:: PMC8542614

Abstract Article PDF–2.6M

Select item 839513219.

CD82 and Gangliosides Tune CD81 Membrane Behavior

Laurent Fernandez, Morgane Malrieu, Christine Bénistant, Patrice Dosset, Eric Rubinstein, Elena Odintsova, Fedor Berditchevski, Pierre-Emmanuel Milhiet

Int J Mol Sci. 2021 Aug; 22(16): 8459. Published online 2021 Aug 6. doi: 10.3390/ijms22168459

PMCID:: PMC8395132

Abstract Article PDF–2.2M

Select item 821471020.

Targeting the tetraspanin CD81 reduces cancer invasion and metastasis

Felipe Vences-Catalán, Ranjani Rajapaksa, Chiung-Chi Kuo, Caitlyn L. Miller, Anderson Lee, Vishnu C. Ramani, Stefanie S. Jeffrey, Ronald Levy, Shoshana Levy

Proc Natl Acad Sci U S A. 2021 Jun 15; 118(24): e2018961118. Published online 2021 Jun 7. doi: 10.1073/pnas.2018961118

PMCID:: PMC8214710

Abstract Article PDF–2.3M

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