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Select item 73084141.

DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner

Patrick L. Collins, Caitlin Purman, Sofia I. Porter, Vincent Nganga, Ankita Saini, Katharina E. Hayer, Greer L. Gurewitz, Barry P. Sleckman, Jeffrey J. Bednarski, Craig H. Bassing, Eugene M. Oltz

Nat Commun. 2020; 11: 3158. Published online 2020 Jun 22. doi: 10.1038/s41467-020-16926-x

PMCID:: PMC7308414

Abstract Article PDF–2.2M

Select item 66057442.

CtIP is essential for early B cell proliferation and development in mice

Xiangyu Liu, Xiaobin S. Wang, Brian J. Lee, Foon K. Wu-Baer, Xiaohui Lin, Zhengping Shao, Verna M. Estes, Jean Gautier, Richard Baer, Shan Zha

J Exp Med. 2019 Jul 1; 216(7): 1648–1663. Published online 2019 May 16. doi: 10.1084/jem.20181139

PMCID:: PMC6605744

Abstract Article PDF–4.0M

Select item 59443463.

Exo1 independent DNA mismatch repair involves multiple compensatory nucleases

Amar Desai, Stanton Gerson

DNA Repair (Amst) Author manuscript; available in PMC 2018 May 10.

Published in final edited form as: DNA Repair (Amst). 2014 Sep; 21: 55–64. Published online 2014 Jul 15. doi: 10.1016/j.dnarep.2014.06.005

PMCID:: PMC5944346

Abstract Article PDF–4.7M

Select item 58312554.

MRE11 promotes tumorigenesis by facilitating resistance to oncogene-induced replication stress

Elizabeth Spehalski, Kayla M. Capper, Cheryl J. Smith, Mary J. Morgan, Maria Dinkelmann, Jeffrey Buis, JoAnn M. Sekiguchi, David O. Ferguson

Cancer Res. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5327–5338. Published online 2017 Aug 17. doi: 10.1158/0008-5472.CAN-17-1355

PMCID:: PMC5831255

Abstract Article PDF–846K

Select item 44151115.

Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during non-homologous end-joining

Wenxia Jiang, Jennifer L. Crowe, Xiangyu Liu, Satoshi Nakajima, Yunyue Wang, Chen Li, Brian J. Lee, Richard L. Dubois, Chao Liu, Xiaochun Yu, Li Lan, Shan Zha

Mol Cell. Author manuscript; available in PMC 2016 Apr 2.

Published in final edited form as: Mol Cell. 2015 Apr 2; 58(1): 172–185. Published online 2015 Mar 26. doi: 10.1016/j.molcel.2015.02.024

PMCID:: PMC4415111

Abstract Article PDF–3.0M

Select item 40790506.

Catalytic and non-catalytic roles of the CtIP endonuclease in double-strand break end resection

Nodar Makharashvili, Anthony T. Tubbs, Soo-Hyun Yang, Hailong Wang, Olivia Barton, Yi Zhou, Rajashree A. Deshpande, Ji-Hoon Lee, Markus Lobrich, Barry P. Sleckman, Xiaohua Wu, Tanya T. Paull

Mol Cell. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Mol Cell. 2014 Jun 19; 54(6): 1022–1033. Published online 2014 May 15. doi: 10.1016/j.molcel.2014.04.011

PMCID:: PMC4079050

Abstract Article PDF–1.1M

Select item 39649647.

The Vertebrate Genome Annotation browser 10 years on

Jennifer L. Harrow, Charles A. Steward, Adam Frankish, James G. Gilbert, Jose M. Gonzalez, Jane E. Loveland, Jonathan Mudge, Dan Sheppard, Mark Thomas, Stephen Trevanion, Laurens G. Wilming

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D771–D779. Published online 2013 Dec 6. doi: 10.1093/nar/gkt1241

PMCID:: PMC3964964

Abstract Article PDF–11M

Select item 38451658.

Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2

Elizabeth A. W. Chan, Grace Teng, Elizabeth Corbett, Kingshuk Roy Choudhury, Craig H. Bassing, David G. Schatz, Michael S. Krangel

Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48): E4628–E4637. Published online 2013 Nov 11. doi: 10.1073/pnas.1310846110

PMCID:: PMC3845165

Abstract Article PDF–1.5M

Select item 38348109.

Opposing roles for 53BP1 during homologous recombination

Andreas Kakarougkas, Amani Ismail, Karolin Klement, Aaron A. Goodarzi, Sandro Conrad, Raimundo Freire, Atsushi Shibata, Markus Lobrich, Penny A. Jeggo

Nucleic Acids Res. 2013 Nov; 41(21): 9719–9731. Published online 2013 Aug 22. doi: 10.1093/nar/gkt729

PMCID:: PMC3834810

Abstract Article PDF–9.7M

Select item 377575110.

Novel Spontaneous Deletion of Artemis Exons 10 and 11 in Mice Leads to T- and B-Cell Deficiency

Christian Barthels, Jacek Puchałka, Tomas Racek, Christoph Klein, Thomas Brocker

PLoS One. 2013; 8(9): e74838. Published online 2013 Sep 17. doi: 10.1371/journal.pone.0074838

PMCID:: PMC3775751

Abstract Article PDF–1.8M

Select item 375386911.

Functional Intersection of ATM and DNA-Dependent Protein Kinase Catalytic Subunit in Coding End Joining during V(D)J Recombination

Baeck-Seung Lee, Eric J. Gapud, Shichuan Zhang, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Elsa Callen, Jeremy A. Daniel, Oleg Osipovich, Eugene M. Oltz, Craig H. Bassing, Andre Nussenzweig, Susan Lees-Miller, Michal Hammel, Benjamin P. C. Chen, Barry P. Sleckman

Mol Cell Biol. 2013 Sep; 33(18): 3568–3579. doi: 10.1128/MCB.00308-13

PMCID:: PMC3753869

Abstract Article PDF–1.7M

Select item 363052212.

Artemis is required to improve the accuracy of repair of double-strand breaks with 5′-blocked termini generated from non-DSB-clustered lesions

Svitlana Malyarchuk, Reneau Castore, Runhua Shi, Lynn Harrison

Mutagenesis. 2013 May; 28(3): 357–366. Published online 2013 Feb 28. doi: 10.1093/mutage/get009

PMCID:: PMC3630522

Abstract Article PDF–1.5M

Select item 357134013.

Cernunnos Deficiency Reduces Thymocyte Life Span and Alters the T Cell Repertoire in Mice and Humans

Gabriella Vera, Paola Rivera-Munoz, Vincent Abramowski, Laurent Malivert, Annick Lim, Christine Bole-Feysot, Christelle Martin, Benoit Florkin, Sylvain Latour, Patrick Revy, Jean-Pierre de Villartay

Mol Cell Biol. 2013 Feb; 33(4): 701–711. doi: 10.1128/MCB.01057-12

PMCID:: PMC3571340

Abstract Article PDF–3.3M

Select item 356835914.

Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining

Valentyn Oksenych, Vipul Kumar, Xiangyu Liu, Chunguang Guo, Bjoern Schwer, Shan Zha, Frederick W. Alt

Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): 2234–2239. Published online 2013 Jan 23. doi: 10.1073/pnas.1222573110

PMCID:: PMC3568359

Abstract Article PDF–711K

Select item 326086415.

RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation

Jeffrey J. Bednarski, Andrew Nickless, Deepta Bhattacharya, Rupesh H. Amin, Mark S. Schlissel, Barry P. Sleckman

J Exp Med. 2012 Jan 16; 209(1): 11–17. doi: 10.1084/jem.20112078

PMCID:: PMC3260864

Abstract Article PDF–1.8M

Select item 325835016.

T and B Cell Immunity can be Reconstituted with Mismatched Hematopoietic Stem Cell Transplantation Without Alkylator Therapy in Artemis-Deficient Mice Using Anti-NK Antibody and Photochemically-Treated Sensitized Donor T Cells

Tony Z Xiao, Kanal Singh, Elizabeth Dunn, Rageshree Ramachandran, Morton J. Cowan

Biol Blood Marrow Transplant. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2012 Feb; 18(2): 200–209. Published online 2011 Oct 19. doi: 10.1016/j.bbmt.2011.10.017

PMCID:: PMC3258350

Abstract Article PDF–597K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316760818.

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

Lisa Woodbine, H. Brunton, A. A. Goodarzi, A. Shibata, P. A. Jeggo

Nucleic Acids Res. 2011 Sep; 39(16): 6986–6997. Published online 2011 May 19. doi: 10.1093/nar/gkr331

PMCID:: PMC3167608

Abstract Article PDF–2.8M

Select item 315059119.

H2AX Prevents CtIP-Mediated DNA End Resection and Aberrant Repair in G1-Phase Lymphocytes

Beth A. Helmink, Anthony T. Tubbs, Yair Dorsett, Jeffrey J. Bednarski, Laura M. Walker, Zhihui Feng, Girdhar Sharma, Peter J. McKinnon, Junran Zhang, Craig H. Bassing, Barry P. Sleckman

Nature. Author manuscript; available in PMC 2011 Aug 4.

Published in final edited form as: Nature. 2011 Jan 13; 469(7329): 245–249. Published online 2010 Dec 15. doi: 10.1038/nature09585