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Items: 1 to 20 of 36

1.
Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin
Tatsuro Hitsumoto, Osamu Tsukamoto, Ken Matsuoka, Junjun Li, Li Liu, Yuki Kuramoto, Shuichiro Higo, Shou Ogawa, Noboru Fujino, Shohei Yoshida, Hidetaka Kioka, Hisakazu Kato, Hideyuki Hakui, Yuki Saito, Chisato Okamoto, Hijiri Inoue, Jo Hyejin, Kyoko Ueda, Takatsugu Segawa, Shunsuke Nishimura, Yoshihiro Asano, Hiroshi Asanuma, Akiyoshi Tani, Riyo Imamura, Shinsuke Komagawa, Toshio Kanai, Masayuki Takamura, Yasushi Sakata, Masafumi Kitakaze, Jun-ichi Haruta, Seiji Takashima
Circulation. 2023 Jun 20; 147(25): 1902–1918. Published online 2023 May 2. doi: 10.1161/CIRCULATIONAHA.122.062885
PMCID:
PMC10270284
AbstractArticlePDF–3.4M
2.
Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3
Tingfei Hu, Hema Kalyanaraman, Renate B. Pilz, Darren E. Casteel
J Biol Chem. 2023 Apr; 299(4): 104584. Published online 2023 Mar 7. doi: 10.1016/j.jbc.2023.104584
PMCID:
PMC10124902
AbstractArticlePDF–1.7M
3.
Mylk3 null C57BL/6N mice develop cardiomyopathy, whereas Nnt null C57BL/6J mice do not
Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Joaquin Botta, Eirini Meimaridou, Avinaash V Maharaj, Michelle Stewart, Andrew Tinker, Roger D Cox, Lou A Metherell
Life Sci Alliance. 2020 Apr; 3(4): e201900593. Published online 2020 Mar 25. doi: 10.26508/lsa.201900593
PMCID:
PMC7103425
AbstractArticlePDF–3.2M
4.
Cardiac MLC2 kinase is localized to the Z-disc and interacts with α-actinin2
Lawrence X. Cai, Yohei Tanada, Gregory D. Bello, James C. Fleming, Fariz F. Alkassis, Thomas Ladd, Todd Golde, Jin Koh, Sixue Chen, Hideko Kasahara
Sci Rep. 2019; 9: 12580. Published online 2019 Aug 29. doi: 10.1038/s41598-019-48884-w
PMCID:
PMC6715661
AbstractArticlePDF–5.4M
5.
Heterozygous Mylk3 Knockout Mice Partially Recapitulate Human DCM With Heterozygous MYLK3 Mutations
Carson L. Tougas, Tabor Grindrod, Lawrence X. Cai, Fariz F. Alkassis, Hideko Kasahara
Front Physiol. 2019; 10: 696. Published online 2019 Jun 6. doi: 10.3389/fphys.2019.00696
PMCID:
PMC6563786
AbstractArticlePDF–1.8M
6.
Turning behaviors of T cells climbing up ramp-like structures are regulated by myosin light chain kinase activity and lamellipodia formation
Kwang Hoon Song, Jaehyun Lee, Hong-Ryul Jung, HyoungJun Park, Junsang Doh
Sci Rep. 2017; 7: 11533. Published online 2017 Sep 14. doi: 10.1038/s41598-017-11938-y
PMCID:
PMC5599526
AbstractArticlePDF–1.9M
7.
Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-κB/MLCK pathway in a mouse endotoxemia model
Jie Han, Ji-Hong Li, Guang Bai, Guo-Shun Shen, Jing Chen, Jia-Nan Liu, Shuo Wang, Xian-Jun Liu
World J Gastroenterol. 2017 Mar 28; 23(12): 2175–2184. Published online 2017 Mar 28. doi: 10.3748/wjg.v23.i12.2175
PMCID:
PMC5374129
AbstractArticlePDF–2.0M
8.
Actin Dynamics and Competition for Myosin Monomer Govern the Sequential Amplification of Myosin Filaments
Jordan R. Beach, Kyle S. Bruun, Lin Shao, Dong Li, Zac Swider, Kirsten Remmert, Yingfan Zhang, Mary A. Conti, Robert S. Adelstein, Nasser M. Rusan, Eric Betzig, John A. Hammer
Nat Cell Biol. Author manuscript; available in PMC 2017 Jul 23.
Published in final edited form as: Nat Cell Biol. 2017 Feb; 19(2): 85–93. Published online 2017 Jan 23. doi: 10.1038/ncb3463
PMCID:
PMC5308804
AbstractArticlePDF–3.6M
9.
Heart Failure Induced by Perinatal Ablation of Cardiac Myosin Light Chain Kinase
Yasmin F. K. Islam, Ryan Joseph, Rajib R. Chowdhury, Robert H. Anderson, Hideko Kasahara
Front Physiol. 2016; 7: 480. Published online 2016 Oct 26. doi: 10.3389/fphys.2016.00480
PMCID:
PMC5080352
AbstractArticlePDF–1.9M
10.
The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly
Stuart J. Smith, Norma Towers, José W. Saldanha, Catherine A. Shang, S. Radma Mahmood, William R. Taylor, Timothy J. Mohun
Dev Biol. 2016 Aug 15; 416(2): 373–388. doi: 10.1016/j.ydbio.2016.05.006
PMCID:
PMC4990356
AbstractArticle
11.
Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities
Audrey N. Chang, Pravin Mahajan, Stefan Knapp, Hannah Barton, H. Lee Sweeney, Kristine E. Kamm, James T. Stull
Proc Natl Acad Sci U S A. 2016 Jul 5; 113(27): E3824–E3833. Published online 2016 Jun 20. doi: 10.1073/pnas.1600633113
PMCID:
PMC4941474
AbstractArticlePDF–1.4M
12.
Acute heart failure with cardiomyocyte atrophy induced in adult mice by ablation of cardiac myosin light chain kinase
Michael T. Massengill, Hassan M. Ashraf, Rajib R. Chowdhury, Stephen M. Chrzanowski, Jeena Kar, Sonisha A. Warren, Glenn A. Walter, Huadong Zeng, Byung-Ho Kang, Robert H. Anderson, Richard L. Moss, Hideko Kasahara
Cardiovasc Res. 2016 Jul 1; 111(1): 34–43. Published online 2016 Mar 29. doi: 10.1093/cvr/cvw069
PMCID:
PMC4909160
AbstractArticlePDF–1.1M
13.
Galectin 3 Regulates HCC cell invasion by RhoA and MLCK activation
Nobuko Serizawa, Jijiang Tian, Hiroo Fukada, Kornelia Baghy, Fiona Scott, Xiangling Chen, Zsofia Kiss, Kristin Olson, Dan Hsu, Fu-Tong Liu, Natalie J Török, Bin Zhao, Joy X. Jiang
Lab Invest. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: Lab Invest. 2015 Oct; 95(10): 1145–1156. Published online 2015 Jul 6. doi: 10.1038/labinvest.2015.77
PMCID:
PMC4586310
AbstractArticlePDF–4.2M
14.
Commensal Bacterial Endocytosis in Epithelial Cells Is Dependent on Myosin Light Chain Kinase–Activated Brush Border Fanning by Interferon-γ
Li-Ling Wu, Wei-Hao Peng, Wei-Ting Kuo, Ching-Ying Huang, Yen-Hsuan Ni, Kuo-Shyan Lu, Jerrold R. Turner, Linda C.H. Yu
Am J Pathol. 2014 Aug; 184(8): 2260–2274. doi: 10.1016/j.ajpath.2014.05.003
Correction in:
Am J Pathol. 2014 Dec; 184(12): 3415.
PMCID:
PMC4188866
AbstractArticlePDF–5.1M
15.
Myosin Light Chain Kinase Expression Induced via Tumor Necrosis Factor Receptor 2 Signaling in the Epithelial Cells Regulates the Development of Colitis-Associated Carcinogenesis
Masahiro Suzuki, Takashi Nagaishi, Motomi Yamazaki, Michio Onizawa, Taro Watabe, Yuriko Sakamaki, Shizuko Ichinose, Mamoru Totsuka, Shigeru Oshima, Ryuichi Okamoto, Motoyuki Shimonaka, Hideo Yagita, Tetsuya Nakamura, Mamoru Watanabe
PLoS One. 2014; 9(2): e88369. Published online 2014 Feb 10. doi: 10.1371/journal.pone.0088369
PMCID:
PMC3919773
AbstractArticlePDF–1.1M
16.
Regulation of Myosin Light Chain Kinase during Insulin-Stimulated Glucose Uptake in 3T3-L1 Adipocytes
Shelly Woody, Richard Stall, Joseph Ramos, Yashomati M. Patel
PLoS One. 2013; 8(10): e77248. Published online 2013 Oct 8. doi: 10.1371/journal.pone.0077248
PMCID:
PMC3792908
AbstractArticlePDF–1.7M
17.
The Effects of Neuregulin on Cardiac Myosin Light Chain Kinase Gene-Ablated Hearts
Audrey N. Chang, Jian Huang, Pavan K. Battiprolu, Joseph A. Hill, Kristine E. Kamm, James T. Stull
PLoS One. 2013; 8(6): e66720. Published online 2013 Jun 11. doi: 10.1371/journal.pone.0066720
PMCID:
PMC3679076
AbstractArticlePDF–1.7M
18.
Mechanism of IL-1β Modulation of Intestinal Epithelial Barrier Involves p38 Kinase and Activating Transcription Factor-2 Activation
Rana Al-Sadi, Shuhong Guo, Dongmei Ye, Karol Dokladny, Tarik Alhmoud, Lisa Ereifej, Hamid M. Said, Thomas Y. Ma
J Immunol. 2013 Jun 15; 190(12): 6596–6606. Published online 2013 Jun 15. doi: 10.4049/jimmunol.1201876
PMCID:
PMC3677168
AbstractArticlePDF–1.2M
19.
Critical Role of Non-Muscle Myosin Light Chain Kinase in Thrombin-Induced Endothelial Cell Inflammation and Lung PMN Infiltration
Fabeha Fazal, Kaiser M. Bijli, Matthew Murrill, Antony Leonard, Mohammad Minhajuddin, Khandaker N. Anwar, Jacob N. Finkelstein, D. Martin Watterson, Arshad Rahman
PLoS One. 2013; 8(3): e59965. Published online 2013 Mar 21. doi: 10.1371/journal.pone.0059965
PMCID:
PMC3605402
AbstractArticlePDF–869K
20.
Signaling through Myosin Light Chain Kinase in Smooth Muscles
Ning Gao, Jian Huang, Weiqi He, Minsheng Zhu, Kristine E. Kamm, James T. Stull
J Biol Chem. 2013 Mar 15; 288(11): 7596–7605. Published online 2013 Jan 28. doi: 10.1074/jbc.M112.427112
PMCID:
PMC3597801
AbstractArticlePDF–3.0M

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