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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107180802.

Fgf8 promotes survival of nephron progenitors by regulating BAX/BAKmediated apoptosis.

Matthew J. Anderson, Salvia Misaghian, Nirmala Sharma, Alan O. Perantoni, Mark Lewandoski

Differentiation. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Differentiation. 2023 Mar-Apr; 130: 7–15. Published online 2022 Dec 6. doi: 10.1016/j.diff.2022.12.001

PMCID:: PMC10718080

Abstract Article PDF–1.9M

Select item 101032623.

Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment

Xiujie Liang, Tamas Aranyi, Jianfu Zhou, Yuting Guan, Hailong Hu, Hongbo Liu, Katalin Susztak

J Am Soc Nephrol. 2023 Apr; 34(4): 572–589. Published online 2022 Dec 15. doi: 10.1681/ASN.2022040460

PMCID:: PMC10103262

Abstract Article

Select item 100855684.

A novel mouse model for an inducible gene modification in the renal thick ascending limb

Laurent Bourqui, Denise V. Winter, Alex Odermatt, Dominique Loffing-Cueni, Johannes Loffing

Am J Physiol Renal Physiol. 2023 May 1; 324(5): F446–F460. Published online 2023 Mar 9. doi: 10.1152/ajprenal.00250.2022

PMCID:: PMC10085568

Abstract Article

Select item 95529095.

Tubular-specific CDK12 knockout causes a defect in urine concentration due to premature cleavage of the slc12a1 gene

Bin Wang, Yao Wang, Yi Wen, Yi-Lin Zhang, Wei-Jie Ni, Tao-Tao Tang, Jing-Yuan Cao, Qing Yin, Wei Jiang, Di Yin, Zuo-Lin Li, Lin-Li Lv, Bi-Cheng Liu

Mol Ther. 2022 Oct 5; 30(10): 3300–3312. Published online 2022 May 16. doi: 10.1016/j.ymthe.2022.05.012

PMCID:: PMC9552909

Abstract Article PDF–5.0M

Select item 95291886.

Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney

Keri A. Drake, Christopher Chaney, Mohita Patel, Amrita Das, Julia Bittencourt, Martin Cohn, Thomas J. Carroll

J Am Soc Nephrol. 2022 Sep; 33(9): 1694–1707. Published online 2022 Sep. doi: 10.1681/ASN.2021121559

Correction in:: J Am Soc Nephrol. 2023 Mar; 34(3): 515–516.

PMCID:: PMC9529188

Abstract Article

Select item 93828997.

Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney

Mary Taglienti, Daniel Graf, Valerie Schumacher, Jordan A. Kreidberg

Development. 2022 Jul 15; 149(14): dev200773. Published online 2022 Jul 25. doi: 10.1242/dev.200773

PMCID:: PMC9382899

Abstract Article

Select item 92329758.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Nan Guan, Hanako Kobayashi, Ken Ishii, Olena Davidoff, Feng Sha, Talat A. Ikizler, Chuan-Ming Hao, Navdeep S. Chandel, Volker H. Haase

Kidney Int. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Kidney Int. 2022 Jul; 102(1): 108–120. Published online 2022 Mar 24. doi: 10.1016/j.kint.2022.02.030

PMCID:: PMC9232975

Abstract Article PDF–1.7M

Select item 88130859.

Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia

Fenglin Wang, Jenny Ngo, Yuwen Li, Hongbing Liu, Chao-Hui Chen, Zubaida Saifudeen, Maria Luisa S Sequeira-Lopez, Samir S. El-Dahr

Epigenetics. 2021; 16(11): 1235–1250. Published online 2020 Dec 29. doi: 10.1080/15592294.2020.1861168

PMCID:: PMC8813085

Abstract Article PDF–6.2M

Select item 856491310.

Impairment in renal medulla development underlies salt wasting in Clc-k2 channel deficiency

Meng-Hsuan Lin, Jen-Chi Chen, Xuejiao Tian, Chia-Ming Lee, I-Shing Yu, Yi-Fen Lo, Shinichi Uchida, Chou-Long Huang, Bi-Chang Chen, Chih-Jen Cheng

JCI Insight. 2021 Oct 22; 6(20): e151039. Published online 2021 Oct 22. doi: 10.1172/jci.insight.151039

PMCID:: PMC8564913

Abstract Article PDF–6.6M

Select item 812647911.

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model

Leticia L. Niborski, Mélanie Paces-Fessy, Pierbruno Ricci, Adeline Bourgeois, Pedro Magalhães, Maria Kuzma-Kuzniarska, Celine Lesaulnier, Martin Reczko, Edwige Declercq, Petra Zürbig, Alain Doucet, Muriel Umbhauer, Silvia Cereghini

Dis Model Mech. 2021 May 1; 14(5): dmm047498. Published online 2021 May 4. doi: 10.1242/dmm.047498

PMCID:: PMC8126479

Abstract Article

Select item 752001412.

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation

Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman

Dev Biol. Author manuscript; available in PMC 2020 Sep 27.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008

PMCID:: PMC7520014

Abstract Article PDF–2.6M

Select item 698581813.

Regulation of NKCC2B by TNF-α in response to salt restriction

Shoujin Hao, Joseph Salzo, Mary Hao, Nicholas R. Ferreri

Am J Physiol Renal Physiol. 2020 Jan 1; 318(1): F273–F282. Published online 2019 Dec 9. doi: 10.1152/ajprenal.00388.2019

PMCID:: PMC6985818

Abstract Article

Select item 685099814.

Impaired glucose tolerance, glucagon, and insulin responses in mice lacking the loop diuretic-sensitive Nkcc2a transporter

Lisa Kelly, Mohammed M. Almutairi, Shams Kursan, Romario Pacheco, Eduardo Dias-Junior, Hayo Castrop, Mauricio Di Fulvio

Am J Physiol Cell Physiol. 2019 Oct 1; 317(4): C843–C856. Published online 2019 Jul 31. doi: 10.1152/ajpcell.00144.2019

PMCID:: PMC6850998

Abstract Article

Select item 682881515.

β-catenin regulates the formation of multiple nephron segments in the mouse kidney

Patrick Deacon, Charles W. Concodora, Eunah Chung, Joo-Seop Park

Sci Rep. 2019; 9: 15915. Published online 2019 Nov 4. doi: 10.1038/s41598-019-52255-w

PMCID:: PMC6828815

Abstract Article PDF–3.3M

Select item 623073616.

With no lysine kinase 4 modulates sodium potassium 2 chloride cotransporter activity in vivo

Andrew S. Terker, Maria Castañeda-Bueno, Mohammed Z. Ferdaus, Ryan J. Cornelius, Kayla J. Erspamer, Xiao-Tong Su, Lauren N. Miller, James A. McCormick, Wen-Hui Wang, Gerardo Gamba, Chao-Ling Yang, David H. Ellison

Am J Physiol Renal Physiol. 2018 Oct 1; 315(4): F781–F790. Published online 2018 Feb 7. doi: 10.1152/ajprenal.00485.2017

PMCID:: PMC6230736

Abstract Article

Select item 617257017.

H⁺-ATPase B1 subunit localizes to thick ascending limb and distal convoluted tubule of rodent and human kidney

Sebastian Frische, Régine Chambrey, Francesco Trepiccione, Reza Zamani, Niels Marcussen, R. Todd Alexander, Karsten Skjødt, Per Svenningsen, Henrik Dimke

Am J Physiol Renal Physiol. 2018 Sep 1; 315(3): F429–F444. Published online 2018 Jul 11. doi: 10.1152/ajprenal.00539.2017

PMCID:: PMC6172570

Abstract Article

Select item 612441518.

Hnf4a deletion in the mouse kidney phenocopies Fanconi renotubular syndrome

Sierra S. Marable, Eunah Chung, Mike Adam, S. Steven Potter, Joo-Seop Park

JCI Insight. 2018 Jul 26; 3(14): e97497. Published online 2018 Jul 25. doi: 10.1172/jci.insight.97497

PMCID:: PMC6124415

Abstract Article PDF–1.2M

Select item 602763519.

Renal-specific silencing of TNF unmasks salt-dependent increases in blood pressure via an NKCC2A-dependent mechanism

Shoujin Hao, Mary Hao, Nicholas R. Ferreri

Hypertension. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Hypertension. 2018 Jun; 71(6): 1117–1125. Published online 2018 May 7. doi: 10.1161/HYPERTENSIONAHA.117.10764

PMCID:: PMC6027635

Abstract Article PDF–1.5M

Select item 594052620.

Reduced Abd-B Hox function during kidney development results in lineage infidelity

Bliss Magella, Robert Mahoney, Mike Adam, S. Steven Potter

Dev Biol. Author manuscript; available in PMC 2019 Jun 15.

Published in final edited form as: Dev Biol. 2018 Jun 15; 438(2): 84–93. Published online 2018 Mar 26. doi: 10.1016/j.ydbio.2018.03.020

PMCID:: PMC5940526

Abstract Article PDF–2.2M

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