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Select item 111427401.

Type 2 cannabinoid receptor expression on microglial cells regulates neuroinflammation during graft-versus-host disease

Alison Moe, Aditya Rayasam, Garrett Sauber, Ravi K. Shah, Ashley Doherty, Cheng-Yin Yuan, Aniko Szabo, Bob M. Moore, II, Marco Colonna, Weiguo Cui, Julian Romero, Anthony E. Zamora, Cecilia J. Hillard, William R. Drobyski

J Clin Invest. 2024 Jun 3; 134(11): e175205. Published online 2024 Apr 25. doi: 10.1172/JCI175205

PMCID:: PMC11142740

Abstract Article PDF–12M

Select item 109678192.

Activation of Cannabinoid Type 2 Receptor in Microglia Reduces Neuroinflammation through Inhibiting Aerobic Glycolysis to Relieve Hypertension

Ruohan Shan, Yuxiang Zhang, Yiping Shi, Xiaowen Wang, Xueke Wang, Guanying Ma, Qian Li

Biomolecules. 2024 Mar; 14(3): 333. Published online 2024 Mar 11. doi: 10.3390/biom14030333

PMCID:: PMC10967819

Abstract Article PDF–4.4M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107681424.

The role of cannabinoid receptor 2 in bone remodeling during orthodontic tooth movement

Deng-ying Fan, Hao-yan Zhai, Yuan Zhao, Xing Qiao, De-chao Zhu, Hui-Juan Liu, Chunyan Liu

BMC Oral Health. 2024; 24: 23. Published online 2024 Jan 4. doi: 10.1186/s12903-023-03810-5

PMCID:: PMC10768142

Abstract Article PDF–1.9M

Select item 107437885.

Role of the CB2 Cannabinoid Receptor in the Regulation of Food Intake: A Systematic Review

Luis Miguel Rodríguez-Serrano, María Elena Chávez-Hernández

Int J Mol Sci. 2023 Dec; 24(24): 17516. Published online 2023 Dec 15. doi: 10.3390/ijms242417516

PMCID:: PMC10743788

Abstract Article PDF–21M

Select item 106001506.

Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication

Yuto Hasegawa, Juhyun Kim, Gianluca Ursini, Yan Jouroukhin, Xiaolei Zhu, Yu Miyahara, Feiyi Xiong, Samskruthi Madireddy, Mizuho Obayashi, Beat Lutz, Akira Sawa, Solange P. Brown, Mikhail V. Pletnikov, Atsushi Kamiya

Nat Commun. 2023; 14: 6559. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42276-5

PMCID:: PMC10600150

Abstract Article PDF–4.8M

Select item 105852307.

Cannabinoid receptor 2 signal promotes type 2 immunity in the lung

Tingting Liu, Jiaqi Liu, Hongjie Chen, Xin Zhou, Wei Fu, Ying Cao, Jing Yang

Cell Insight. 2023 Oct; 2(5): 100124. Published online 2023 Oct 6. doi: 10.1016/j.cellin.2023.100124

PMCID:: PMC10585230

Abstract Article PDF–3.4M

Select item 103331778.

Pharmacological blockade of cannabinoid receptor 2 signaling does not affect LPS/IFN-γ-induced microglial activation

Bolanle Fatimat Olabiyi, Anne-Caroline Schmoele, Eva Carolina Beins, Andreas Zimmer

Sci Rep. 2023; 13: 11105. Published online 2023 Jul 10. doi: 10.1038/s41598-023-37702-z

Correction in:: Sci Rep. 2023; 13: 15699.

PMCID:: PMC10333177

Abstract Article PDF–1.9M

Select item 101784569.

The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Non-Melanoma Skin Cancer

Jennifer Ana Iden, Bitya Raphael-Mizrahi, Aaron Naim, Albert Kolomansky, Tamar Liron, Drorit Neumann, Marilena Vered, Yankel Gabet

Int J Mol Sci. 2023 May; 24(9): 7773. Published online 2023 Apr 24. doi: 10.3390/ijms24097773

PMCID:: PMC10178456

Abstract Article PDF–2.6M

Select item 1001770910.

Structural basis of selective cannabinoid CB₂ receptor activation

Xiaoting Li, Hao Chang, Jara Bouma, Laura V. de Paus, Partha Mukhopadhyay, Janos Paloczi, Mohammed Mustafa, Cas van der Horst, Sanjay Sunil Kumar, Lijie Wu, Yanan Yu, Richard J. B. H. N. van den Berg, Antonius P. A. Janssen, Aron Lichtman, Zhi-Jie Liu, Pal Pacher, Mario van der Stelt, Laura H. Heitman, Tian Hua

Nat Commun. 2023; 14: 1447. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37112-9

PMCID:: PMC10017709

Abstract Article PDF–4.0M

Select item 996197411.

The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Colon Cancer: A Study in Mice and Humans

Jennifer Ana Iden, Bitya Raphael-Mizrahi, Zamzam Awida, Aaron Naim, Dan Zyc, Tamar Liron, Melody Kasher, Gregory Livshits, Marilena Vered, Yankel Gabet

Int J Mol Sci. 2023 Feb; 24(4): 4060. Published online 2023 Feb 17. doi: 10.3390/ijms24044060

PMCID:: PMC9961974

Abstract Article PDF–2.8M

Select item 992855712.

Update on the controversial identity of cells expressing cnr2 gene in the nervous system

Wanda Grabon, Jacques Bodennec, Sylvain Rheims, Amor Belmeguenai, Laurent Bezin

CNS Neurosci Ther. 2023 Mar; 29(3): 760–770. Published online 2023 Jan 5. doi: 10.1111/cns.13977

PMCID:: PMC9928557

Abstract Article PDF–1.3M

Select item 986866613.

Cannabinoid receptor 2 plays a pro-tumorigenic role in non-small cell lung cancer by limiting anti-tumor activity of CD8⁺ T and NK cells

Arailym Sarsembayeva, Melanie Kienzl, Eva Gruden, Dusica Ristic, Kathrin Maitz, Paulina Valadez-Cosmes, Ana Santiso, Carina Hasenoehrl, Luka Brcic, Jörg Lindenmann, Julia Kargl, Rudolf Schicho

Front Immunol. 2022; 13: 997115. Published online 2023 Jan 9. doi: 10.3389/fimmu.2022.997115

PMCID:: PMC9868666

Abstract Article PDF–9.5M

Select item 984518014.

Peripheral sensory neuron CB2 cannabinoid receptors are necessary for both CB2-mediated antinociceptive efficacy and sparing of morphine tolerance in a mouse model of anti-retroviral toxic neuropathy

Lawrence M. Carey, Zhili Xu, Gabriela Rajic, Alexandros Makriyannis, Julian Romero, Cecilia Hillard, Ken Mackie, Andrea G. Hohmann

Pharmacol Res. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Pharmacol Res. 2023 Jan; 187: 106560. Published online 2022 Nov 20. doi: 10.1016/j.phrs.2022.106560

PMCID:: PMC9845180

Abstract Article PDF–2.5M

Select item 967235415.

The endocannabinoid anandamide is an airway relaxant in health and disease

Annika Simon, Thomas von Einem, Alexander Seidinger, Michaela Matthey, Laura Bindila, Daniela Wenzel

Nat Commun. 2022; 13: 6941. Published online 2022 Nov 17. doi: 10.1038/s41467-022-34327-0

PMCID:: PMC9672354

Abstract Article PDF–1019K

Select item 965666416.

Antagonization of OX₁ Receptor Potentiates CB₂ Receptor Function in Microglia from APP_Sw/Ind Mice Model

Iu Raïch, Joan Biel Rebassa, Jaume Lillo, Arnau Cordomi, Rafael Rivas-Santisteban, Alejandro Lillo, Irene Reyes-Resina, Rafael Franco, Gemma Navarro

Int J Mol Sci. 2022 Nov; 23(21): 12801. Published online 2022 Oct 24. doi: 10.3390/ijms232112801

PMCID:: PMC9656664

Abstract Article PDF–3.4M

Select item 955332117.

Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury

Fan Jiang, Mingjie Xia, Yanan Zhang, Jie Chang, Jiang Cao, Zhongkai Zhang, Zhanyang Qian, Lei Yang

Front Immunol. 2022; 13: 993168. Published online 2022 Sep 26. doi: 10.3389/fimmu.2022.993168

PMCID:: PMC9553321

Abstract Article PDF–25M

Select item 946016518.

Yin and yang of cannabinoid CB1 receptor: CB1 deletion in immune cells causes exacerbation while deletion in non-immune cells attenuates obesity

Kathryn Miranda, William Becker, Philip B. Busbee, Nicholas Dopkins, Osama A. Abdulla, Yin Zhong, Jiajia Zhang, Mitzi Nagarkatti, Prakash S. Nagarkatti

iScience. 2022 Sep 16; 25(9): 104994. Published online 2022 Aug 24. doi: 10.1016/j.isci.2022.104994

PMCID:: PMC9460165

Abstract Article PDF–2.8M

Select item 902708819.

Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice

Amaya Austrich-Olivares, María Salud García-Gutiérrez, Lucía Illescas, Ani Gasparyan, Jorge Manzanares

Pharmaceuticals (Basel) 2022 Apr; 15(4): 473. Published online 2022 Apr 13. doi: 10.3390/ph15040473

PMCID:: PMC9027088

Abstract Article PDF–2.6M

Select item 901372820.

Cannabinoid Receptor II engagement promotes ILC2 expansion and enhances ILC2-dependent airway hyperreactivity

Benjamin P. Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Emily Howard, Jacob D. Painter, Christine Quach, Omid Akbari

J Allergy Clin Immunol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2022 May; 149(5): 1628–1642.e10. Published online 2021 Oct 18. doi: 10.1016/j.jaci.2021.09.037

PMCID:: PMC9013728

Abstract Article PDF–1.5M

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