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Select item 111803451.

Inhibition of hepatic p63 ameliorates steatohepatitis with fibrosis in mice

Marcos F. Fondevila, Eva Novoa, Uxia Fernandez, Valentina Dorta, Tamara Parracho, Henriette Kreimeyer, Maria Garcia-Vence, Maria P. Chantada-Vazquez, Susana B. Bravo, Begoña Porteiro, Alba Cabaleiro, Mijra Koning, Ana Senra, Yara Souto, Joanne Verheij, Diana Guallar, Miguel Fidalgo, Abraham S. Meijnikman, Natalia da Silva Lima, Carlos Dieguez, Maria J. Gonzalez-Rellan, Ruben Nogueiras

Mol Metab. 2024 Jul; 85: 101962. Published online 2024 May 28. doi: 10.1016/j.molmet.2024.101962

PMCID:: PMC11180345

Abstract Article PDF–6.9M

Select item 110812242.

ΔNp63 regulates Sfrp1 expression to direct salivary gland branching morphogenesis

Theresa Wrynn, Sangwon Min, Erich Horeth, Jason Osinski, Satrajit Sinha, Rose-Anne Romano

PLoS One. 2024; 19(5): e0301082. Published online 2024 May 9. doi: 10.1371/journal.pone.0301082

PMCID:: PMC11081224

Abstract Article PDF–7.0M

Select item 110041803.

Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis

Naveen Kumar, Pon Ganish Prakash, Christian Wentland, Shilpa Mary Kurian, Gaurav Jethva, Volker Brinkmann, Hans-Joachim Mollenkopf, Tobias Krammer, Christophe Toussaint, Antoine-Emmanuel Saliba, Matthias Biebl, Christian Jürgensen, Bertram Wiedenmann, Thomas F. Meyer, Rajendra Kumar Gurumurthy, Cindrilla Chumduri

Nat Commun. 2024; 15: 3064. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47173-z

PMCID:: PMC11004180

Abstract Article PDF–23M

Select item 109547594.

Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer

Yuan Jiang, Yueyuan Zheng, Yuan-Wei Zhang, Shuai Kong, Jinxiu Dong, Fei Wang, Benjamin Ziman, Sigal Gery, Jia-Jie Hao, Dan Zhou, Jianian Zhou, Allen S. Ho, Uttam K. Sinha, Jian Chen, Shuo Zhang, Chuntong Yin, Dan-Dan Wei, Masaharu Hazawa, Huaguang Pan, Zhihao Lu, Wen-Qiang Wei, Ming-Rong Wang, H. Phillip Koeffler, De-Chen Lin, Yan-Yi Jiang

Nat Commun. 2024; 15: 2484. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46785-9

PMCID:: PMC10954759

Abstract Article PDF–8.0M

Select item 109519885.

ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer

Ukjin Kim, Rahul Debnath, Javier E. Maiz, Joshua Rico, Satrajit Sinha, Mario Andrés Blanco, Rumela Chakrabarti

iScience. 2024 Apr 19; 27(4): 109366. Published online 2024 Feb 29. doi: 10.1016/j.isci.2024.109366

PMCID:: PMC10951988

Abstract Article PDF–8.5M

Select item 106564276.

GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter

Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert

Development. 2022 Aug 1; 149(15): dev200522. Published online 2022 Jul 29. doi: 10.1242/dev.200522

PMCID:: PMC10656427

Abstract Article

Select item 106511227.

Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development

Justin Malin, Gustavo Ulises Martinez-Ruiz, Yongge Zhao, Susannah C. Shissler, Jennifer E. Cowan, Yi Ding, Abigail Morales-Sanchez, Masaki Ishikawa, Marieke Lavaert, Arundhoti Das, Donna Butcher, Andrew C. Warner, Melissa Kallarakal, Jingqiu Chen, Noemi Kedei, Michael Kelly, Lauren R. Brinster, David Allman, Avinash Bhandoola

Sci Adv. 2023 Nov 17; 9(46): eadg8126. Published online 2023 Nov 15. doi: 10.1126/sciadv.adg8126

PMCID:: PMC10651122

Abstract Article PDF–1.6M

Select item 106020078.

The roles of JAK2/STAT3 signaling in fusion of the secondary palate

Naoki Yoshida, Toshihiro Inubushi, Takumi Hirose, Gozo Aoyama, Hiroshi Kurosaka, Takashi Yamashiro

Dis Model Mech. 2023 Oct 1; 16(10): dmm050085. Published online 2023 Oct 17. doi: 10.1242/dmm.050085

PMCID:: PMC10602007

Abstract Article

Select item 105889569.

CHEK2 signaling is the key regulator of oocyte survival after chemotherapy

Chihiro Emori, Zachary Boucher, Ewelina Bolcun-Filas

Sci Adv. 2023 Oct 20; 9(42): eadg0898. Published online 2023 Oct 20. doi: 10.1126/sciadv.adg0898

PMCID:: PMC10588956

Abstract Article PDF–2.6M

Select item 1039213710.

Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63

Qiuling Li, Jie Jiao, Ya Heng, Qingshuang Lu, Yu Zheng, Huijun Li, Jun Cai, Mei Mei, Shilai Bao

J Biol Chem. 2023 Aug; 299(8): 104964. Published online 2023 Jun 24. doi: 10.1016/j.jbc.2023.104964

PMCID:: PMC10392137

Abstract Article PDF–4.2M

Select item 1039049211.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1036206212.

MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

Dongmei Wang, Haimin Li, Navdeep S. Chandel, Yali Dou, Rui Yi

Nat Commun. 2023; 14: 4404. Published online 2023 Jul 21. doi: 10.1038/s41467-023-40108-0

PMCID:: PMC10362062

Abstract Article PDF–9.3M

Select item 1030043313.

Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches

Satu-Marja Myllymäki, Beata Kaczyńska, Qiang Lan, Marja L. Mikkola

J Cell Biol. 2023 Sep 4; 222(9): e202209005. Published online 2023 Jun 27. doi: 10.1083/jcb.202209005

PMCID:: PMC10300433

Abstract Article PDF–11M

Select item 1027677014.

Arid1a regulates bladder urothelium formation and maintenance

Chunming Guo, Yingsheng Zhang, Ruirong Tan, Zonghao Tang, Christa M. Lam, Xing Ye, Zhong Wang, Xue Li

Dev Biol. Author manuscript; available in PMC 2023 Jun 18.

Published in final edited form as: Dev Biol. 2022 May; 485: 61–69. Published online 2022 Mar 10. doi: 10.1016/j.ydbio.2022.02.008

PMCID:: PMC10276770

Abstract Article PDF–2.6M

Select item 1014690015.

ZFP750 affects the cutaneous barrier through regulating lipid metabolism

Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino

Sci Adv. 2023 Apr; 9(17): eadg5423. Published online 2023 Apr 28. doi: 10.1126/sciadv.adg5423

PMCID:: PMC10146900

Abstract Article PDF–2.3M

Select item 1004160016.

Periderm Fate during Palatogenesis: TGF-β and Periderm Dedifferentiation

G. Saroya, J. Hu, M. Hu, C. Panaretos, J. Mann, S. Kim, J.O. Bush, V. Kaartinen

J Dent Res. 2023 Apr; 102(4): 459–466. Published online 2023 Feb 7. doi: 10.1177/00220345221146454

PMCID:: PMC10041600

Abstract Article PDF–3.3M

Select item 998434417.

Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells

Evelien Eenjes, Floor Benthem, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Dick Tibboel, Robbert J. Rottier

Cell Mol Life Sci. 2023 Mar; 80(3): 79. Published online 2023 Mar 3. doi: 10.1007/s00018-023-04731-w

PMCID:: PMC9984344

Abstract Article PDF–5.3M

Select item 997409518.

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

Chengzi Huang, Simin Zhao, Yajuan Yang, Ting Guo, Hanni Ke, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao

J Clin Invest. 2023 Mar 1; 133(5): e162315. Published online 2023 Mar 1. doi: 10.1172/JCI162315

PMCID:: PMC9974095

Abstract Article PDF–3.1M

Select item 995045819.

ΔNp63 maintains the fidelity of the myoepithelial cell lineage and directs cell differentiation programs in the murine salivary gland

Eun-Ah Christine Song, Monika Che, Jason Osinski, Kirsten Smalley, Erich Horeth, Satrajit Sinha, Rose-Anne Romano

Cell Death Differ. 2023 Feb; 30(2): 515–526. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01101-0

PMCID:: PMC9950458

Abstract Article PDF–12M

Select item 993316220.

Hepatic p63 regulates glucose metabolism by repressing SIRT1

Maria J Gonzalez-Rellan, Eva Novoa, Natalia da Silva Lima, Amaia Rodriguez, Christelle Veyrat-Durebex, Samuel Seoane, Begoña Porteiro, Marcos F Fondevila, Uxia Fernandez, Marta Varela-Rey, Ana Senra, Cristina Iglesias, Adriana Escudero, Miguel Fidalgo, Diana Guallar, Roman Perez-Fernandez, Vincent Prevot, Markus Schwaninger, Miguel López, Carlos Dieguez, Roberto Coppari, Gema Frühbeck, Ruben Nogueiras

Gut. 2023 Mar; 72(3): 472–483. Published online 2022 May 17. doi: 10.1136/gutjnl-2021-326620

PMCID:: PMC9933162

Abstract Article PDF–6.1M

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