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Select item 111140321.

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

Bin Yang, Peishan Hu, Xihua Lin, Wei Han, Liyuan Zhu, Xiaochao Tan, Fei Ye, Guanzhou Wang, Fan Wu, Bin Yin, Zhaoshi Bao, Tao Jiang, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng

Cell Mol Life Sci. 2015 Nov; 72(22): 4383–4397. Published online 2015 Jun 6. doi: 10.1007/s00018-015-1938-7

PMCID:: PMC11114032

Abstract Article PDF–3.0M

Select item 110724562.

The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function

Praveen Koganti, Venkata Narasimha Kadali, Dhanoop Manikoth Ayyathan, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank

Cell Mol Life Sci. 2022 May; 79(5): 237. Published online 2022 Apr 11. doi: 10.1007/s00018-022-04272-8

PMCID:: PMC11072456

Abstract Article PDF–6.5M

Select item 110197523.

Multifaceted roles of RNA editing enzyme ADAR1 in innate immunity

Inga Jarmoskaite, Jin Billy Li

RNA. 2024 May; 30(5): 500–511. doi: 10.1261/rna.079953.124

PMCID:: PMC11019752

Abstract Article PDF–1.5M

Select item 109938564.

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells

Kyle A. Cottrell, Sua Ryu, Jackson R. Pierce, Luisangely Soto Torres, Holly E. Bohlin, Angela M. Schab, Jason D. Weber

Cancer Res Commun. 2024 Apr; 4(4): 986–1003. Published online 2024 Apr 4. doi: 10.1158/2767-9764.CRC-23-0488

PMCID:: PMC10993856

Abstract Article PDF–13M

Select item 109623565.

Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing

Maria Rivera, Haoran Zhang, Jessica Pham, Jane Isquith, Qingchen Jenny Zhou, Larisa Balaian, Roman Sasik, Sabina Enlund, Adam Mark, Wenxue Ma, Frida Holm, Kathleen M. Fisch, Dennis John Kuo, Catriona Jamieson, Qingfei Jiang

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2024 Feb 27; 43(2): 113704. Published online 2024 Jan 23. doi: 10.1016/j.celrep.2024.113704

PMCID:: PMC10962356

Abstract Article PDF–1.9M

Select item 109424676.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 108722547.

Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1

Agya Karki, Kristen B Campbell, Sukanya Mozumder, Andrew J. Fisher, Peter A. Beal

Biochemistry. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochemistry. 2024 Feb 6; 63(3): 282–293. Published online 2024 Jan 8. doi: 10.1021/acs.biochem.3c00405

PMCID:: PMC10872254

Abstract Article PDF–1.7M

Select item 107580988.

ADAR1 protects pulmonary macrophages from sepsis-induced pyroptosis and lung injury through miR-21/A20 signaling

Xiaojun Zhao, Jiangang Xie, Chujun Duan, Linxiao Wang, Yi Si, Shanshou Liu, Qianmei Wang, Dan Wu, Yifan Wang, Wen Yin, Ran Zhuang, Junjie Li

Int J Biol Sci. 2024; 20(2): 464–485. Published online 2024 Jan 1. doi: 10.7150/ijbs.86424

PMCID:: PMC10758098

Abstract Article PDF–13M

Select item 106817459.

ADAR1 links R-loop homeostasis to ATR activation in replication stress response

Biao Zhang, Yi Li, Jieyou Zhang, Yuejiao Wang, Can Liang, Ting Lu, Chunyong Zhang, Ling Liu, Yan Qin, Jiahuan He, Xiangnan Zhao, Jia Yu, Jihui Hao, Jie Yang, Mulin Jun Li, Zhi Yao, Shuai Ma, Hui Cheng, Tao Cheng, Lei Shi

Nucleic Acids Res. 2023 Nov 27; 51(21): 11668–11687. Published online 2023 Oct 13. doi: 10.1093/nar/gkad839

PMCID:: PMC10681745

Abstract Article PDF–3.8M

Select item 1040462410.

RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing

Yanfang Xing, Taisuke Nakahama, Yuke Wu, Maal Inoue, Jung In Kim, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara

J Biol Chem. 2023 Jul; 299(7): 104840. Published online 2023 May 18. doi: 10.1016/j.jbc.2023.104840

PMCID:: PMC10404624

Abstract Article PDF–2.2M

Select item 1037396511.

Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer

Hao Yu, Kexin Bai, Yidong Cheng, Jiancheng Lv, Qiang Song, Haiwei Yang, Qiang Lu, Xiao Yang

Aging (Albany NY) 2023 Jul 15; 15(13): 6302–6330. Published online 2023 Jul 6. doi: 10.18632/aging.204853

PMCID:: PMC10373965

Abstract Article PDF–18M

Select item 1035820412.

ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma

Wendi Yang, Kehong Chen, Qian Yu, Rongxin Liao, Hengqiu He, Yuan Peng, Zhenzhou Yang, Xiaoyue Zhang

Cancer Med. 2023 Jul; 12(13): 14820–14832. Published online 2023 May 10. doi: 10.1002/cam4.6044

PMCID:: PMC10358204

Abstract Article PDF–20M

Select item 1025846213.

RNA Editing Enzyme ADAR1 Suppresses the Mobility of Cancer Cells via ARPIN

Min Ji Park, Eunji Jeong, Eun Ji Lee, Hyeon Ji Choi, Bo Hyun Moon, Keunsoo Kang, Suhwan Chang

Mol Cells. 2023 Jun 30; 46(6): 351–359. Published online 2023 Mar 16. doi: 10.14348/molcells.2023.2174

Correction in:: Mol Cells. 2023 Nov 30; 46(11): 725.

PMCID:: PMC10258462

Abstract Article PDF–1.5M

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1020607015.

Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer

Najat Binothman, Majidah Aljadani, Bandar Alghanem, Mohammed Y. Refai, Mamoon Rashid, Abeer Al Tuwaijri, Nouf H. Alsubhi, Ghadeer I. Alrefaei, Muhammad Yasir Khan, Sultan N. Sonbul, Fadwa Aljoud, Sultan Alhayyani, Rwaa H. Abdulal, Magdah Ganash, Anwar M. Hashem

Sci Rep. 2023; 13: 8341. Published online 2023 May 23. doi: 10.1038/s41598-023-35517-6

PMCID:: PMC10206070

Abstract Article PDF–2.7M

Select item 1019909316.

ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer

Tin-Lok Wong, Jia-Jian Loh, Shixun Lu, Helen H. N. Yan, Hoi Cheong Siu, Ren Xi, Dessy Chan, Max J. F. Kam, Lei Zhou, Man Tong, John A. Copland, Leilei Chen, Jing-Ping Yun, Suet Yi Leung, Stephanie Ma

Nat Commun. 2023; 14: 2861. Published online 2023 May 19. doi: 10.1038/s41467-023-38581-8

PMCID:: PMC10199093

Abstract Article PDF–6.6M

Select item 1016456417.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 1015161518.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1003652619.

ADAR1 has an oncogenic function and can be a prognostic factor in cervical cancer

Keiichiro Nakamura, Kunitoshi Shigeyasu, Kazuhiro Okamoto, Hirofumi Matsuoka, Hisashi Masuyama

Sci Rep. 2023; 13: 4720. Published online 2023 Mar 23. doi: 10.1038/s41598-023-30452-y

PMCID:: PMC10036526

Abstract Article PDF–9.4M

Select item 998681720.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762