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Items: 1 to 20 of 31

1.
Aplp1 interacts with Lag3 to facilitate transmission of pathologic α-synuclein
Xiaobo Mao, Hao Gu, Donghoon Kim, Yasuyoshi Kimura, Ning Wang, Enquan Xu, Ramhari Kumbhar, Xiaotian Ming, Haibo Wang, Chan Chen, Shengnan Zhang, Chunyu Jia, Yuqing Liu, Hetao Bian, Senthilkumar S. Karuppagounder, Fatih Akkentli, Qi Chen, Longgang Jia, Heehong Hwang, Su Hyun Lee, Xiyu Ke, Michael Chang, Amanda Li, Jun Yang, Cyrus Rastegar, Manjari Sriparna, Preston Ge, Saurav Brahmachari, Sangjune Kim, Shu Zhang, Yasushi Shimoda, Martina Saar, Haiqing Liu, Sin Ho Kweon, Mingyao Ying, Creg J. Workman, Dario A. A. Vignali, Ulrike C. Muller, Cong Liu, Han Seok Ko, Valina L. Dawson, Ted M. Dawson
Nat Commun. 2024; 15: 4663. Published online 2024 May 31. doi: 10.1038/s41467-024-49016-3
Correction in:
Nat Commun. 2024; 15: 6413.
PMCID:
PMC11143359
AbstractArticlePDF–3.3M
2.
Regulation of gene expression by the APP family in the adult cerebral cortex
Hye Ji Cha, Jie Shen, Jongkyun Kang
Sci Rep. 2022; 12: 66. Published online 2022 Jan 7. doi: 10.1038/s41598-021-04027-8
PMCID:
PMC8741778
AbstractArticlePDF–2.8M
3.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
4.
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease
Shengnan Zhang, Yu-Qing Liu, Chunyu Jia, Yeh-Jun Lim, Guoqin Feng, Enquan Xu, Houfang Long, Yasuyoshi Kimura, Youqi Tao, Chunyu Zhao, Chuchu Wang, Zhenying Liu, Jin-Jian Hu, Meng-Rong Ma, Zhijun Liu, Lin Jiang, Dan Li, Renxiao Wang, Valina L. Dawson, Ted M. Dawson, Yan-Mei Li, Xiaobo Mao, Cong Liu
Proc Natl Acad Sci U S A. 2021 Jun 29; 118(26): e2011196118. Published online 2021 Jun 25. doi: 10.1073/pnas.2011196118
PMCID:
PMC8256039
AbstractArticlePDF–2.8M
5.
Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism‐like phenotype
Vicky Steubler, Susanne Erdinger, Michaela K Back, Susann Ludewig, Dominique Fässler, Max Richter, Kang Han, Lutz Slomianka, Irmgard Amrein, Jakob von Engelhardt, David P Wolfer, Martin Korte, Ulrike C Müller
EMBO J. 2021 Jun 15; 40(12): e107471. Published online 2021 May 19. doi: 10.15252/embj.2020107471
PMCID:
PMC8204861
AbstractArticlePDF–3.7M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival
Sang Hun Lee, Jongkyun Kang, Angela Ho, Hirotaka Watanabe, Vadim Y. Bolshakov, Jie Shen
Neuron. Author manuscript; available in PMC 2021 Nov 25.
Published in final edited form as: Neuron. 2020 Nov 25; 108(4): 676–690.e8. Published online 2020 Sep 4. doi: 10.1016/j.neuron.2020.08.011
PMCID:
PMC7704911
AbstractArticlePDF–2.9M
8.
Mutation in Sodium-Glucose Cotransporter 2 Results in Down-Regulation of Amyloid Beta (A4) Precursor-Like Protein 1 in Young Age, Which May Lead to Poor Memory Retention in Old Age
Keiko Unno, Yoshiichi Takagi, Tomokazu Konishi, Mitsuhiro Suzuki, Akiyuki Miyake, Takumi Kurotaki, Tadashi Hase, Shinichi Meguro, Atsuyoshi Shimada, Sanae Hasegawa-Ishii, Monira Pervin, Kyoko Taguchi, Yoriyuki Nakamura
Int J Mol Sci. 2020 Aug; 21(15): 5579. Published online 2020 Aug 4. doi: 10.3390/ijms21155579
PMCID:
PMC7432872
AbstractArticlePDF–1.1M
9.
Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1
Ramin Homayouni, Dennis S. Rice, Michael Sheldon, Tom Curran
J Neurosci. 1999 Sep 1; 19(17): 7507–7515. doi: 10.1523/JNEUROSCI.19-17-07507.1999
PMCID:
PMC6782519
AbstractArticlePDF–633K
10.
Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members
Sabine Heber, Jochen Herms, Vladan Gajic, Johannes Hainfellner, Adriano Aguzzi, Thomas Rülicke, Hans Kretzschmar, Cornelia von Koch, Sangram Sisodia, Phillippe Tremml, Hans-Peter Lipp, David P. Wolfer, Ulrike Müller
J Neurosci. 2000 Nov 1; 20(21): 7951–7963. doi: 10.1523/JNEUROSCI.20-21-07951.2000
Correction in:
J Neurosci. 2020 Sep 16; 40(38): 7375.
PMCID:
PMC6772747
AbstractArticlePDF–814K
11.
c-Jun N-Terminal Kinase (JNK)-Interacting Protein-1b/Islet-Brain-1 Scaffolds Alzheimer's Amyloid Precursor Protein with JNK
Shuji Matsuda, Takashi Yasukawa, Yasuko Homma, Yuko Ito, Takako Niikura, Takako Hiraki, Shuichi Hirai, Shigeo Ohno, Yoshiko Kita, Masaoki Kawasumi, Keisuke Kouyama, Tokuo Yamamoto, John M. Kyriakis, Ikuo Nishimoto
J Neurosci. 2001 Sep 1; 21(17): 6597–6607. doi: 10.1523/JNEUROSCI.21-17-06597.2001
PMCID:
PMC6763068
AbstractArticlePDF–555K
12.
APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission
Sandra Schilling, Annika Mehr, Susann Ludewig, Jonathan Stephan, Marius Zimmermann, Alexander August, Paul Strecker, Martin Korte, Edward H. Koo, Ulrike C. Müller, Stefan Kins, Simone Eggert
J Neurosci. 2017 May 24; 37(21): 5345–5365. doi: 10.1523/JNEUROSCI.1875-16.2017
PMCID:
PMC6596463
AbstractArticlePDF–5.9M
13.
Secreted Amyloid-β Precursor Protein Functions as a GABABR1a Ligand to Modulate Synaptic Transmission
Heather C. Rice, Daniel de Malmazet, An Schreurs, Samuel Frere, Inge Van Molle, Alexander N. Volkov, Eline Creemers, Irena Vertkin, Julie Nys, Fanomezana M. Ranaivoson, Davide Comoletti, Jeffrey N. Savas, Han Remaut, Detlef Balschun, Keimpe D. Wierda, Inna Slutsky, Karl Farrow, Bart De Strooper, Joris de Wit
Science. Author manuscript; available in PMC 2019 Jul 11.
Published in final edited form as: Science. 2019 Jan 11; 363(6423): eaao4827. doi: 10.1126/science.aao4827
PMCID:
PMC6366617
AbstractArticlePDF–1.1M
14.
Amyloid-precursor Like Proteins APLP1 and APLP2 Are Dispensable for Normal Development of the Neonatal Respiratory Network
Kang Han, Ulrike C. Müller, Swen Hülsmann
Front Mol Neurosci. 2017; 10: 189. Published online 2017 Jun 22. doi: 10.3389/fnmol.2017.00189
PMCID:
PMC5479907
AbstractArticlePDF–4.6M
15.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
16.
Crystal Structure of the E2 Domain of Amyloid Precursor Protein-like Protein 1 in Complex with Sucrose Octasulfate
Yi Xue, Sangwon Lee, Yongcheng Wang, Ya Ha
J Biol Chem. 2011 Aug 26; 286(34): 29748–29757. Published online 2011 Jun 29. doi: 10.1074/jbc.M111.219659
Correction in:
J Biol Chem. 2013 Nov 29; 288(48): 34756.
PMCID:
PMC3191016
AbstractArticlePDF–2.0M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Presynaptic and Postsynaptic Interaction of the Amyloid Precursor Protein Promotes Peripheral and Central Synaptogenesis
Zilai Wang, Baiping Wang, Li Yang, Qinxi Guo, Nadia Aithmitti, Zhou Songyang, Hui Zheng
J Neurosci. 2009 Sep 2; 29(35): 10788–10801. doi: 10.1523/JNEUROSCI.2132-09.2009
PMCID:
PMC2757256
AbstractArticlePDF–8.0M
20.
Identification of transcripts with enriched expression in the developing and adult pancreas
Brad G Hoffman, Bogard Zavaglia, Joy Witzsche, Teresa Ruiz de Algara, Mike Beach, Pamela A Hoodless, Steven JM Jones, Marco A Marra, Cheryl D Helgason
Genome Biol. 2008; 9(6): R99. Published online 2008 Jun 14. doi: 10.1186/gb-2008-9-6-r99
PMCID:
PMC2481431
AbstractArticlePDF–2.2M

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