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Select item 92792851.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 91714112.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 91197363.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77681945.

IMiDs induce FAM83F degradation via an interaction with CK1α to attenuate Wnt signalling

Karen Dunbar, Thomas J Macartney, Gopal P Sapkota

Life Sci Alliance. 2021 Feb; 4(2): e202000804. Published online 2020 Dec 23. doi: 10.26508/lsa.202000804

PMCID:: PMC7768194

Abstract Article PDF–3.0M

Select item 74273276.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73568557.

FAM83G Is a Novel Inducer of Apoptosis

Junichi Okada, Noriaki Sunaga, Eijiro Yamada, Tsugumichi Saito, Atsushi Ozawa, Yasuyo Nakajima, Kazuya Okada, Jeffrey E. Pessin, Shuichi Okada, Masanobu Yamada

Molecules. 2020 Jun; 25(12): 2810. Published online 2020 Jun 18. doi: 10.3390/molecules25122810

PMCID:: PMC7356855

Abstract Article PDF–3.2M

Select item 60257938.

The DUF1669 domain of FAM83 family proteins anchor Casein Kinase 1 isoforms

Luke J Fulcher, Polyxeni Bozatzi, Theresa Tachie-Menson, Kevin Z L Wu, Timothy D Cummins, Joshua C Bufton, Daniel M Pinkas, Karen Dunbar, Sabin Shrestha, Nicola T Wood, Simone Weidlich, Thomas J Macartney, Joby Varghese, Robert Gourlay, David G Campbell, Kevin S Dingwell, James C Smith, Alex N Bullock, Gopal P Sapkota

Sci Signal. Author manuscript; available in PMC 2018 Nov 22.

Published in final edited form as: Sci Signal. 2018 May 22; 11(531): eaao2341. Published online 2018 May 22. doi: 10.1126/scisignal.aao2341

PMCID:: PMC6025793

Abstract Article PDF–3.5M

Select item 58914369.

PAWS1 controls Wnt signalling through association with casein kinase 1α

Polyxeni Bozatzi, Kevin S Dingwell, Kevin ZL Wu, Fay Cooper, Timothy D Cummins, Luke D Hutchinson, Janis Vogt, Nicola T Wood, Thomas J Macartney, Joby Varghese, Robert Gourlay, David G Campbell, James C Smith, Gopal P Sapkota

EMBO Rep. 2018 Apr; 19(4): e44807. Published online 2018 Mar 7. doi: 10.15252/embr.201744807

PMCID:: PMC5891436

Abstract Article PDF–4.5M

Select item 582692610.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 581805411.

PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP

Timothy D. Cummins, Kevin Z. L. Wu, Polyxeni Bozatzi, Kevin S. Dingwell, Thomas J. Macartney, Nicola T. Wood, Joby Varghese, Robert Gourlay, David G. Campbell, Alan Prescott, Eric Griffis, James C. Smith, Gopal P. Sapkota

J Cell Sci. 2018 Jan 1; 131(1): jcs202390. doi: 10.1242/jcs.202390

PMCID:: PMC5818054

Abstract Article

Select item 553358512.

The human cytoplasmic dynein interactome reveals novel activators of motility

William B Redwine, Morgan E DeSantis, Ian Hollyer, Zaw Min Htet, Phuoc Tien Tran, Selene K Swanson, Laurence Florens, Michael P Washburn, Samara L Reck-Peterson

eLife. 2017; 6: e28257. Published online 2017 Jul 18. doi: 10.7554/eLife.28257

PMCID:: PMC5533585

Abstract Article PDF–5.9M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 407704915.

Lenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells

Jan Krönke, Namrata D. Udeshi, Anupama Narla, Peter Grauman, Slater N. Hurst, Marie McConkey, Tanya Svinkina, Dirk Heckl, Eamon Comer, Xiaoyu Li, Christie Ciarlo, Emily Hartman, Nikhil Munshi, Monica Schenone, Stuart L. Schreiber, Steven A. Carr, Benjamin L. Ebert

Science. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Science. 2014 Jan 17; 343(6168): 301–305. Published online 2013 Nov 29. doi: 10.1126/science.1244851

PMCID:: PMC4077049

Abstract Article PDF–987K

Select item 393805316.

Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling

Janis Vogt, Kevin S. Dingwell, Lina Herhaus, Robert Gourlay, Thomas Macartney, David Campbell, James C. Smith, Gopal P. Sapkota

Open Biol. 2014 Feb; 4(2): 130210. Published online 2014 Feb 19. doi: 10.1098/rsob.130210

PMCID:: PMC3938053

Abstract Article PDF–925K

Select item 366378017.

The wooly mutation (wly) on mouse chromosome 11 is associated with a genetic defect in Fam83g

Legairre A Radden, Kevin M Child, Elisabeth B Adkins, Damek V Spacek, Aaron M Feliciano, Thomas R King

BMC Res Notes. 2013; 6: 189. Published online 2013 May 9. doi: 10.1186/1756-0500-6-189

PMCID:: PMC3663780

Abstract Article PDF–1.7M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 270227819.

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS

Serhiy Havrylov, Yuriy Rzhepetskyy, Agata Malinowska, Lyudmyla Drobot, Maria Jolanta Redowicz

Proteome Sci. 2009; 7: 21. Published online 2009 Jun 16. doi: 10.1186/1477-5956-7-21

PMCID:: PMC2702278

Abstract Article PDF–2.5M

Select item 270004820.

Identification of Novel Smad2 and Smad3 Associated Proteins in Response to TGF-β1

Kimberly A. Brown, Amy-Joan L. Ham, Cara N. Clark, Nahum Meller, Brian K. Law, Anna Chytil, Nikki Cheng, Jennifer A. Pietenpol, Harold L. Moses

J Cell Biochem. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: J Cell Biochem. 2008 Oct 1; 105(2): 596–611. doi: 10.1002/jcb.21860

PMCID:: PMC2700048

Abstract Article PDF–1.1M

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