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Select item 109165511.

NNMT/1‐MNA Promote Cell‐Cycle Progression of Breast Cancer by Targeting UBC12/Cullin‐1‐Mediated Degradation of P27 Proteins

Yilei Ma, Xucheng Huang, Yanzhong Wang, Yinjiao Lei, Jinwei Yu, Shaobo Yu, Yuzhen Gao, Jun Yang, Feng Zhao, Haitao Yu, Jin Zeng, Yadong Chu, Min Yang, Guoli Li, Xinyou Xie, Jun Zhang

Adv Sci (Weinh) 2024 Mar; 11(9): 2305907. Published online 2023 Dec 21. doi: 10.1002/advs.202305907

PMCID:: PMC10916551

Abstract Article PDF–5.1M

Select item 106836142.

Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression

Qirong Wen, Xiaohui Xie, Caiyuan Chen, Bolun Wen, Yaqiong Liu, Jie Zhou, Xiaobin Lin, Han Jin, Kun Shi

Aging (Albany NY) 2023 Nov 15; 15(21): 11860–11874. Published online 2023 Oct 25. doi: 10.18632/aging.205142

PMCID:: PMC10683614

Abstract Article PDF–1.6M

Select item 105732173.

Proteomics Profiling of Bladder Cancer Tissues from Early to Advanced Stages Reveals NNMT and GALK1 as Biomarkers for Early Detection and Prognosis of BCa

Katarina Davalieva, Sanja Kiprijanovska, Ognen Ivanovski, Aleksandar Trifunovski, Skender Saidi, Aleksandar Dimovski, Zivko Popov

Int J Mol Sci. 2023 Oct; 24(19): 14938. Published online 2023 Oct 6. doi: 10.3390/ijms241914938

PMCID:: PMC10573217

Abstract Article PDF–4.2M

Select item 105658764.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 104133545.

Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance

Mohammad Rehan, Brian Deskin, Ashish R. Kurundkar, Santosh Yadav, Yasuka Matsunaga, Justin Manges, Nia Smith, Kevin G. Dsouza, Matthew E. Burow, Victor J. Thannickal

J Biol Chem. 2023 Aug; 299(8): 105027. Published online 2023 Jul 7. doi: 10.1016/j.jbc.2023.105027

PMCID:: PMC10413354

Abstract Article PDF–2.9M

Select item 100226866.

Myosin-X recruits lamellipodin to filopodia tips

Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L. B. Grönloh, Neil J. Ball, Benjamin T. Goult, Johanna Ivaska, Guillaume Jacquemet

J Cell Sci. 2023 Mar 1; 136(5): jcs260574. Published online 2023 Mar 2. doi: 10.1242/jcs.260574

PMCID:: PMC10022686

Abstract Article

Select item 99349847.

NNMT Is an Immune-Related Prognostic Biomarker That Modulates the Tumor Microenvironment in Pan-Cancer

Wenxiu Liu, Meng Zhu, Xiaoming Li, Limian Er, Shengmian Li

Dis Markers. 2023; 2023: 9226712. Published online 2023 Feb 9. doi: 10.1155/2023/9226712

PMCID:: PMC9934984

Abstract Article PDF–3.3M

Select item 95997338.

Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma

Weixian Zhang, Yue Jing, Shuai Wang, Yan Wu, Yawei Sun, Jia Zhuang, Xiaofeng Huang, Sheng Chen, Xiaoxin Zhang, Yuxian Song, Qingang Hu, Yanhong Ni

Biomolecules. 2022 Oct; 12(10): 1487. Published online 2022 Oct 15. doi: 10.3390/biom12101487

PMCID:: PMC9599733

Abstract Article PDF–3.5M

Select item 88547029.

Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer

Makiko Ogawa, Atsushi Tanaka, Kei Namba, Jinru Shia, Julia Y. Wang, Michael H. A. Roehrl

Sci Rep. 2022; 12: 2767. Published online 2022 Feb 17. doi: 10.1038/s41598-022-06772-w

PMCID:: PMC8854702

Abstract Article PDF–2.1M

Select item 881017910.

Knockdown of long non-coding RNA HOTAIR promotes bone marrow mesenchymal stem cell differentiation by sponging microRNA miR-378g that inhibits nicotinamide N-methyltransferase

Wei Wang, Tao Li, Shibo Feng

Bioengineered. 2021; 12(2): 12482–12497. Published online 2021 Dec 13. doi: 10.1080/21655979.2021.2006863

PMCID:: PMC8810179

Abstract Article PDF–2.9M

Select item 880673011.

Long non-coding RNA XIST promotes osteoporosis by inhibiting the differentiation of bone marrow mesenchymal stem cell by sponging miR-29b-3p that suppresses nicotinamide N-methyltransferase

Jiang Yu, Min Xiao, Guohai Ren

Bioengineered. 2021; 12(1): 6057–6069. Published online 2021 Sep 5. doi: 10.1080/21655979.2021.1967711

PMCID:: PMC8806730

Abstract Article PDF–2.4M

Select item 870524412.

Alterations in Kynurenine and NAD⁺ Salvage Pathways during the Successful Treatment of Inflammatory Bowel Disease Suggest HCAR3 and NNMT as Potential Drug Targets

Artur Wnorowski, Sylwia Wnorowska, Jacek Kurzepa, Jolanta Parada-Turska

Int J Mol Sci. 2021 Dec; 22(24): 13497. Published online 2021 Dec 16. doi: 10.3390/ijms222413497

PMCID:: PMC8705244

Abstract Article PDF–2.2M

Select item 860245113.

Identification of proximal SUMO-dependent interactors using SUMO-ID

Orhi Barroso-Gomila, Fredrik Trulsson, Veronica Muratore, Iñigo Canosa, Laura Merino-Cacho, Ana Rosa Cortazar, Coralia Pérez, Mikel Azkargorta, Ibon Iloro, Arkaitz Carracedo, Ana M. Aransay, Felix Elortza, Ugo Mayor, Alfred C. O. Vertegaal, Rosa Barrio, James D. Sutherland

Nat Commun. 2021; 12: 6671. Published online 2021 Nov 18. doi: 10.1038/s41467-021-26807-6

PMCID:: PMC8602451

Abstract Article PDF–11M

Select item 853352914.

Nicotinamide N-Methyltransferase: An Emerging Protagonist in Cancer Macro(r)evolution

Richard B. Parsons, Paul D. Facey

Biomolecules. 2021 Oct; 11(10): 1418. Published online 2021 Sep 28. doi: 10.3390/biom11101418

PMCID:: PMC8533529

Abstract Article PDF–2.5M

Select item 793295915.

High Expression of Nicotinamide N-Methyltransferase in Patients with Sporadic Alzheimer’s Disease

Altin Kocinaj, Tabassum Chaudhury, Mohammed S. Uddin, Rashad R. Junaid, David B. Ramsden, Geshanthi Hondhamuni, Fábio Klamt, Linda Parsons, Richard B. Parsons

Mol Neurobiol. 2021; 58(4): 1769–1781. Published online 2021 Jan 2. doi: 10.1007/s12035-020-02259-9

PMCID:: PMC7932959

Abstract Article PDF–13M

Select item 790549016.

Accumulation of Nicotinamide N-Methyltransferase (NNMT) in Cancer-associated Fibroblasts: A Potential Prognostic and Predictive Biomarker for Gastric Carcinoma

Li Zhang, Mengmeng Song, Fan Zhang, Hao Yuan, Wenjun Chang, Guanyu Yu, Yongdong Niu

J Histochem Cytochem. 2021 Mar; 69(3): 165–176. Published online 2020 Dec 7. doi: 10.1369/0022155420976590

PMCID:: PMC7905490

Abstract Article PDF–5.6M

Select item 780974017.

Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer

Jun Li, Huiran Yue, Hailin Yu, Xin Lu, Xiaohong Xue

BMC Cancer. 2021; 21: 67. Published online 2021 Jan 14. doi: 10.1186/s12885-021-07785-w

PMCID:: PMC7809740

Abstract Article PDF–1.4M

Select item 739233418.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Abstract Article PDF–2.7M

Select item 735174619.

Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

Maciel Bañales-Luna, Nicté Figueroa-Vega, Carolina Ivet Marín-Aragón, Elva Perez-Luque, Lorena Ibarra-Reynoso, Hugo L. Gallardo-Blanco, Itzel López-Aguilar, Juan Manuel Malacara

Sci Rep. 2020; 10: 11478. Published online 2020 Jul 10. doi: 10.1038/s41598-020-67832-7

PMCID:: PMC7351746

Abstract Article PDF–1.0M

Select item 730600520.

Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer

Shaokun Shu, Hua-Jun Wu, Jennifer Y. Ge, Rhamy Zeid, Isaac S. Harris, Bojana Jovanović, Katherine Murphy, Binbin Wang, Xintao Qiu, Jennifer E. Endress, Jaime Reyes, Klothilda Lim, Alba Font-Tello, Sudeepa Syamala, Tengfei Xiao, Chandra Sekhar Reddy Chilamakuri, Evangelia K. Papachristou, Clive D’Santos, Jayati Anand, Kunihiko Hinohara, Wei Li, Thomas O. McDonald, Adrienne Luoma, Rebecca J. Modiste, Quang-De Nguyen, Brittany Michel, Paloma Cejas, Cigall Kadoch, Jacob D. Jaffe, Kai W. Wucherpfennig, Jun Qi, X. Shirley Liu, Henry Long, Myles Brown, Jason S. Carroll, Joan S. Brugge, James Bradner, Franziska Michor, Kornelia Polyak

Mol Cell. Author manuscript; available in PMC 2021 Jun 18.

Published in final edited form as: Mol Cell. 2020 Jun 18; 78(6): 1096–1113.e8. Published online 2020 May 15. doi: 10.1016/j.molcel.2020.04.027

PMCID:: PMC7306005

Abstract Article PDF–3.2M

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