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Select item 110003121.

SALL4 in gastrointestinal tract cancers: upstream and downstream regulatory mechanisms

Tairan Wang, Yan Jin, Mengyao Wang, Boya Chen, Jinyu Sun, Jiaying Zhang, Hui Yang, Xinyao Deng, Xingyue Cao, Lidong Wang, Yuanyuan Tang

Mol Med. 2024; 30: 46. Published online 2024 Apr 8. doi: 10.1186/s10020-024-00812-z

PMCID:: PMC11000312

Abstract Article PDF–2.5M

Select item 108500992.

SALL4 is a CRL3^REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma

Ludovica Lospinoso Severini, Elena Loricchio, Shirin Navacci, Irene Basili, Romina Alfonsi, Flavia Bernardi, Marta Moretti, Marilisa Conenna, Antonino Cucinotta, Sonia Coni, Marialaura Petroni, Enrico De Smaele, Giuseppe Giannini, Marella Maroder, Gianluca Canettieri, Angela Mastronuzzi, Daniele Guardavaccaro, Olivier Ayrault, Paola Infante, Francesca Bufalieri, Lucia Di Marcotullio

Cell Death Differ. 2024 Feb; 31(2): 170–187. Published online 2023 Dec 7. doi: 10.1038/s41418-023-01246-6

PMCID:: PMC10850099

Abstract Article PDF–7.7M

Select item 103238883.

Angélique Vienot, Franck Monnien, Caroline Truntzer, Virginie Mougey, Adeline Bouard, Jean‐René Pallandre, Chloé Molimard, Romain Loyon, Kamal Asgarov, Gerlinde Averous, François Ghiringhelli, Frédéric Bibeau, Paul Peixoto, Christophe Borg

Mol Oncol. 2023 Jul; 17(7): 1356–1378. Published online 2023 Jan 21. doi: 10.1002/1878-0261.13370

PMCID:: PMC10323888

Abstract Article PDF–9.2M

Select item 103157224.

SALL4 correlates with proliferation, metastasis, and poor prognosis in prostate cancer by affecting MAPK pathway

Jie Zhou, Shengmeng Peng, Huiyang Fan, Jin Li, Zean Li, Ganping Wang, Lexiang Zeng, Zhenghui Guo, Yiming Lai, Hai Huang

Cancer Med. 2023 Jun; 12(12): 13471–13485. Published online 2023 Apr 29. doi: 10.1002/cam4.5998

PMCID:: PMC10315722

Abstract Article PDF–4.4M

Select item 98382175.

Structure of SALL4 zinc finger domain reveals link between AT-rich DNA binding and Okihiro syndrome

James A Watson, Raphaël Pantier, Uma Jayachandran, Kashyap Chhatbar, Beatrice Alexander-Howden, Valdeko Kruusvee, Michal Prendecki, Adrian Bird, Atlanta G Cook

Life Sci Alliance. 2023 Mar; 6(3): e202201588. Published online 2023 Jan 12. doi: 10.26508/lsa.202201588

PMCID:: PMC9838217

Abstract Article PDF–2.7M

Select item 98317416.

SALL4 activates PI3K/AKT signaling pathway through targeting PTEN, thus facilitating migration, invasion and proliferation of hepatocellular carcinoma cells

Zhipeng Tang, Pei Zhao, Wanxing Zhang, Qian Zhang, Ming Zhao, He Tan

Aging (Albany NY) 2022 Dec 31; 14(24): 10081–10092. Published online 2022 Dec 26. doi: 10.18632/aging.204446

PMCID:: PMC9831741

Abstract Article PDF–1.7M

Select item 96556357.

Role of SALL4 in HER2+ Breast Cancer Progression: Regulating PI3K/AKT Pathway

Birlipta Pattanayak, Ana Lameirinhas, Sandra Torres-Ruiz, Octavio Burgués, Ana Rovira, María Teresa Martínez, Marta Tapia, Sandra Zazo, Joan Albanell, Federico Rojo, Begoña Bermejo, Pilar Eroles

Int J Mol Sci. 2022 Nov; 23(21): 13292. Published online 2022 Oct 31. doi: 10.3390/ijms232113292

PMCID:: PMC9655635

Abstract Article PDF–1.7M

Select item 91773098.

The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4

Wenjuan Zhang, Yan Hu, Wenbing Zhang, Ke Yi, Xiaohui Xu, Zhihua Chen

J Immunol Res. 2022; 2022: 9385820. Published online 2022 Jun 1. doi: 10.1155/2022/9385820

PMCID:: PMC9177309

Abstract Article PDF–1.5M

Select item 90189369.

SALL-4 and Beta-Catenin Expression in Sinonasal Teratocarcinosarcoma

Margaret L. Compton, James S. Lewis, Jr., William C. Faquin, Nicole A. Cipriani, Qiuying Shi, Kim A. Ely

Head Neck Pathol. 2022 Mar; 16(1): 229–235. Published online 2021 Jun 9. doi: 10.1007/s12105-021-01343-3

PMCID:: PMC9018936

Abstract Article PDF–1.1M

Select item 892305710.

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava

Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021

PMCID:: PMC8923057

Abstract Article PDF–2.5M

Select item 886747011.

A de novo mutation of SALL4 in a Chinese family with Okihiro syndrome

Xiuli Ma, Rui Huang, Guo Li, Tiesong Zhang, Jing Ma

Mol Med Rep. 2022 Apr; 25(4): 131. Published online 2022 Feb 17. doi: 10.3892/mmr.2022.12647

PMCID:: PMC8867470

Abstract Article PDF–3.2M

Select item 880029212.

Co-expression of cancer stem cell markers, SALL4/ALDH1A1, is associated with tumor aggressiveness and poor survival in patients with serous ovarian carcinoma

Mina Sharbatoghli, Parisa Shamshiripour, Fahimeh Fattahi, Elham Kalantari, Zohre Habibi Shams, Mahshid Panahi, Mehdi Totonchi, Zeynab Asadi-Lari, Zahra Madjd, Leili Saeednejad Zanjani

J Ovarian Res. 2022; 15: 17. Published online 2022 Jan 28. doi: 10.1186/s13048-021-00921-x

PMCID:: PMC8800292

Abstract Article PDF–4.1M

Select item 856658213.

miR-497-5p/SALL4 axis promotes stemness phenotype of choriocarcinoma and forms a feedback loop with DNMT-mediated epigenetic regulation

Zheng Peng, Yi Zhang, Dazun Shi, Yanyan Jia, Huirong Shi, Huining Liu

Cell Death Dis. 2021 Nov; 12(11): 1046. Published online 2021 Nov 3. doi: 10.1038/s41419-021-04315-1

PMCID:: PMC8566582

Abstract Article PDF–5.9M

Select item 837918314.

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Johanna Diener, Arianna Baggiolini, Mattias Pernebrink, Damian Dalcher, Luigi Lerra, Phil F. Cheng, Sandra Varum, Jessica Häusel, Salome Stierli, Mathias Treier, Lorenz Studer, Konrad Basler, Mitchell P. Levesque, Reinhard Dummer, Raffaella Santoro, Claudio Cantù, Lukas Sommer

Nat Commun. 2021; 12: 5056. Published online 2021 Aug 20. doi: 10.1038/s41467-021-25326-8

PMCID:: PMC8379183

Abstract Article PDF–3.3M

Select item 824686315.

Cross‐linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex

Cornelia G. Spruijt, Cathrin Gräwe, Simone C. Kleinendorst, Marijke P. A. Baltissen, Michiel Vermeulen

FEBS J. 2021 May; 288(10): 3231–3245. Published online 2020 Dec 14. doi: 10.1111/febs.15650

PMCID:: PMC8246863

Abstract Article PDF–3.1M

Select item 819765816.

Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression

Nikki R. Kong, Mahmoud A. Bassal, Hong Kee Tan, Jesse V. Kurland, Kol Jia Yong, John J. Young, Yang Yang, Fudong Li, Jonathan D. Lee, Yue Liu, Chan-Shuo Wu, Alicia Stein, Hongbo R. Luo, Leslie E. Silberstein, Martha L. Bulyk, Daniel G. Tenen, Li Chai

Cell Rep. Author manuscript; available in PMC 2021 Jun 12.

Published in final edited form as: Cell Rep. 2021 Jan 5; 34(1): 108574. doi: 10.1016/j.celrep.2020.108574

PMCID:: PMC8197658

Abstract Article PDF–1.4M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 796299418.

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Yanke Chen, Ting Jiang, Hongyi Zhang, Xingchun Gou, Cong Han, Jianhui Wang, Ann T. Chen, Jun Ma, Jun Liu, Zeming Chen, Xintao Jing, Hong Lei, Zhenzhen Wang, Youmei Bao, Mehdi Baqri, Yong Zhu, Ranjit S. Bindra, James E. Hansen, Jun Dou, Chen Huang, Jiangbing Zhou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Nat Cell Biol. 2020 Oct; 22(10): 1276–1285. Published online 2020 Oct 1. doi: 10.1038/s41556-020-00586-6

PMCID:: PMC7962994

Abstract Article PDF–5.5M

Select item 788305519.

Thalidomide and its metabolite 5‐hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF

Satoshi Yamanaka, Hidetaka Murai, Daisuke Saito, Gembu Abe, Etsuko Tokunaga, Takahiro Iwasaki, Hirotaka Takahashi, Hiroyuki Takeda, Takayuki Suzuki, Norio Shibata, Koji Tamura, Tatsuya Sawasaki

EMBO J. 2021 Feb 15; 40(4): e105375. Published online 2021 Jan 20. doi: 10.15252/embj.2020105375

PMCID:: PMC7883055

Abstract Article PDF–2.3M

Select item 784113020.

Knockdown of SALL4 Inhibits Proliferation, Migration, and Invasion in Osteosarcoma Cells

Dengfeng Zhang, Feng Jiang, Xiao Wang, Guojun Li

Oncol Res. 2017; 25(5): 763–771. Published online 2017 May 24. doi: 10.3727/096504016X14772402056137

PMCID:: PMC7841130

Abstract Article PDF–4.6M

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