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Items: 1 to 20 of 28

1.
DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients
Souvik Ghatak, Shakti Ranjan Satapathy, Anita Sjölander
Int J Mol Sci. 2023 Feb; 24(4): 3409. Published online 2023 Feb 8. doi: 10.3390/ijms24043409
PMCID:
PMC9963074
AbstractArticlePDF–3.5M
2.
The CysLT2R receptor mediates leukotriene C4-driven acute and chronic itch
Tiphaine Voisin, Caroline Perner, Marie-Angele Messou, Stephanie Shiers, Saltanat Ualiyeva, Yoshihide Kanaoka, Theodore J. Price, Caroline L. Sokol, Lora G. Bankova, K. Frank Austen, Isaac M. Chiu
Proc Natl Acad Sci U S A. 2021 Mar 30; 118(13): e2022087118. Published online 2021 Mar 22. doi: 10.1073/pnas.2022087118
PMCID:
PMC8020753
AbstractArticlePDF–1.6M
3.
Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling
Emilie Ceraudo, Mizuho Horioka, Jordan M. Mattheisen, Tyler D. Hitchman, Amanda R. Moore, Manija A. Kazmi, Ping Chi, Yu Chen, Thomas P. Sakmar, Thomas Huber
J Biol Chem. 2021 Jan-Jun; 296: 100163. Published online 2020 Dec 11. doi: 10.1074/jbc.RA120.015352
PMCID:
PMC7948404
AbstractArticlePDF–1.0M
4.
Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma
Rogier J. Nell, Nino V. Menger, Mieke Versluis, Gregorius P. M. Luyten, Robert M. Verdijk, Michele C. Madigan, Martine J. Jager, Pieter A. van der Velden
BMC Cancer. 2021; 21: 164. Published online 2021 Feb 15. doi: 10.1186/s12885-021-07865-x
PMCID:
PMC7885466
AbstractArticlePDF–1.8M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
7.
Proteome‐wide analysis of phospho‐regulated PDZ domain interactions
Gustav N Sundell, Roland Arnold, Muhammad Ali, Piangfan Naksukpaiboon, Julien Orts, Peter Güntert, Celestine N Chi, Ylva Ivarsson
Mol Syst Biol. 2018 Aug; 14(8): e8129. Published online 2018 Aug 20. doi: 10.15252/msb.20178129
PMCID:
PMC6100724
AbstractArticlePDF–2.4M
8.
Activating cysteinyl leukotriene receptor 2 (CYSLTR2) mutations in blue nevi
Inga Möller, Rajmohan Murali, Hansgeorg Müller, Thomas Wiesner, Louise A Jackett, Simone L Scholz, Ioana Cosgarea, Johannes AP van de Nes, Antje Sucker, Uwe Hillen, Bastian Schilling, Annette Paschen, Heinz Kutzner, Arno Rütten, Martin Böckers, Richard A Scolyer, Dirk Schadendorf, Klaus G Griewank
Mod Pathol. Author manuscript; available in PMC 2018 Mar 1.
Published in final edited form as: Mod Pathol. 2017 Mar; 30(3): 350–356. Published online 2016 Dec 9. doi: 10.1038/modpathol.2016.201
PMCID:
PMC5518680
AbstractArticlePDF–1.3M
9.
Systematic protein–protein interaction mapping for clinically relevant human GPCRs
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar
Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430
PMCID:
PMC5371730
AbstractArticlePDF–4.1M
10.
Recurrent activating mutations of G-protein-coupled receptor CYSLTR2 in uveal melanoma
Amanda R Moore, Emilie Ceraudo, Jessica J Sher, Youxin Guan, Alexander N Shoushtari, Matthew T Chang, Jenny Q Zhang, Edward G Walczak, Manija A Kazmi, Barry S Taylor, Thomas Huber, Ping Chi, Thomas P Sakmar, Yu Chen
Nat Genet. Author manuscript; available in PMC 2016 Sep 22.
Published in final edited form as: Nat Genet. 2016 Jun; 48(6): 675–680. Published online 2016 Apr 18. doi: 10.1038/ng.3549
PMCID:
PMC5032652
AbstractArticlePDF–1.4M
11.
Individual protomers of a G protein-coupled receptor dimer integrate distinct functional modules
Nathan D Camp, Kyung-Soon Lee, Jennifer L Wacker-Mhyre, Timothy S Kountz, Ji-Min Park, Dorathy-Ann Harris, Marianne Estrada, Aaron Stewart, Alejandro Wolf-Yadlin, Chris Hague
Cell Discov. 2015; 1: 15011. Published online 2015 Jun 16. doi: 10.1038/celldisc.2015.11
PMCID:
PMC4658663
AbstractArticlePDF–2.7M
12.
Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes
Ylva Ivarsson, Roland Arnold, Megan McLaughlin, Satra Nim, Rakesh Joshi, Debashish Ray, Bernard Liu, Joan Teyra, Tony Pawson, Jason Moffat, Shawn Shun-Cheng Li, Sachdev S. Sidhu, Philip M. Kim
Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7): 2542–2547. Published online 2014 Feb 3. doi: 10.1073/pnas.1312296111
PMCID:
PMC3932933
AbstractArticlePDF–1.0M
13.
The cysteinyl leukotriene 2 receptor contributes to all-trans retinoic acid-induced differentiation of colon cancer cells
Astrid M Bengtsson, Gunilla Jönsson, Cecilia Magnusson, Tavga Salim, Cecilia Axelsson, Anita Sjölander
BMC Cancer. 2013; 13: 336. Published online 2013 Jul 8. doi: 10.1186/1471-2407-13-336
PMCID:
PMC3710469
AbstractArticlePDF–1.9M
14.
Regulation of Cysteinyl Leukotriene Receptor 2 Expression—A Potential Anti-Tumor Mechanism
Cecilia Magnusson, Astrid M. Bengtsson, Minghui Liu, Jian Liu, Yvonne Ceder, Roy Ehrnström, Anita Sjölander
PLoS One. 2011; 6(12): e29060. Published online 2011 Dec 15. doi: 10.1371/journal.pone.0029060
PMCID:
PMC3240642
AbstractArticlePDF–754K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
The multiple-specificity landscape of modular peptide recognition domains
David Gfeller, Frank Butty, Marta Wierzbicka, Erik Verschueren, Peter Vanhee, Haiming Huang, Andreas Ernst, Nisa Dar, Igor Stagljar, Luis Serrano, Sachdev S Sidhu, Gary D Bader, Philip M Kim
Mol Syst Biol. 2011; 7: 484. Published online 2011 Apr 26. doi: 10.1038/msb.2011.18
PMCID:
PMC3097085
AbstractArticlePDF–2.1M
17.
Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells
Ladan Parhamifar, Wondossen Sime, Yuliana Yudina, Frederik Vilhardt, Matthias Mörgelin, Anita Sjölander
PLoS One. 2010; 5(12): e14439. Published online 2010 Dec 28. doi: 10.1371/journal.pone.0014439
PMCID:
PMC3010979
AbstractArticlePDF–1.1M
18.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
19.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
20.
Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization
Jeong-Ah Shin, Hun Soo Chang, Se-Min Park, An-Soo Jang, Sung Woo Park, Jong Sook Park, Soo-Taek Uh, Gune Il Lim, Taiyoun Rhim, Mi-Kyeong Kim, Inseon S Choi, Il Yup Chung, Byung Lae Park, Hyoung Doo Shin, Choon-Sik Park
BMC Med Genet. 2009; 10: 106. Published online 2009 Oct 20. doi: 10.1186/1471-2350-10-106
PMCID:
PMC2770054
AbstractArticlePDF–595K

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