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Select item 110114361.

Role of Sphingosine Kinase 1 in Glucolipotoxicity-Induced Early Activation of Autophagy in INS-1 Pancreatic β Cells

Nicolas Coant, Karima Rendja, Lara Bellini, Mélissa Flamment, Jeannine Lherminier, Bernard Portha, Patrice Codogno, Hervé Le Stunff

Cells. 2024 Apr; 13(7): 636. Published online 2024 Apr 5. doi: 10.3390/cells13070636

PMCID:: PMC11011436

Abstract Article PDF–6.3M

Select item 78937782.

Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury

Chenjian Wang, Tianzhen Xu, Brittany Bolduc Lachance, Xiqiang Zhong, Guangjie Shen, Tao Xu, Chengxuan Tang, Xiaofeng Jia

J Neuroinflammation. 2021; 18: 50. Published online 2021 Feb 18. doi: 10.1186/s12974-021-02092-4

PMCID:: PMC7893778

Abstract Article PDF–11M

Select item 77197083.

Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-δ in sepsis-associated liver injury

Tao Tian, Danhua Yao, Lei Zheng, Zhiyuan Zhou, Yantao Duan, Bin Liu, Pengfei Wang, Yousheng Li

Cell Death Dis. 2020 Dec; 11(12): 1037. Published online 2020 Dec 6. doi: 10.1038/s41419-020-03255-6

PMCID:: PMC7719708

Abstract Article PDF–2.6M

Select item 71635824.

The Sphkl/SlP pathway regulates angiogenesis via NOS/NO synthesis following cerebral ischemia‐reperfusion

Man-Hua Lv, Shi Li, Yong‐Jia Jiang, Wei Zhang

CNS Neurosci Ther. 2020 May; 26(5): 538–548. Published online 2019 Dec 8. doi: 10.1111/cns.13275

PMCID:: PMC7163582

Abstract Article PDF–1.9M

Select item 59432835.

Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes

Jose F. Moruno-Manchon, Ndidi-Ese Uzor, Chandrashekar R. Ambati, Vivekananda Shetty, Nagireddy Putluri, Chinnaswamy Jagannath, Louise D. McCullough, Andrey S. Tsvetkov

Cell Death Dis. 2018 May; 9(5): 521. Published online 2018 May 9. doi: 10.1038/s41419-018-0599-5

PMCID:: PMC5943283

Abstract Article PDF–1.3M

Select item 59025546.

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

Ju Youn Lee, Seung Hoon Han, Min Hee Park, Bosung Baek, Im-Sook Song, Min-Koo Choi, Yoh Takuwa, Hoon Ryu, Seung Hyun Kim, Xingxuan He, Edward H. Schuchman, Jae-Sung Bae, Hee Kyung Jin

Nat Commun. 2018; 9: 1479. Published online 2018 Apr 16. doi: 10.1038/s41467-018-03674-2

PMCID:: PMC5902554

Abstract Article PDF–2.6M

Select item 58705857.

Extracellular vesicles from human-induced pluripotent stem cell-derived mesenchymal stromal cells (hiPSC-MSCs) protect against renal ischemia/reperfusion injury via delivering specificity protein (SP1) and transcriptional activating of sphingosine kinase 1 and inhibiting necroptosis

Xiaodong Yuan, Dawei Li, Xiaosong Chen, Conghui Han, Longmei Xu, Tao Huang, Zhen Dong, Ming Zhang

Cell Death Dis. 2017 Dec; 8(12): 3200. Published online 2017 Dec 11. doi: 10.1038/s41419-017-0041-4

PMCID:: PMC5870585

Abstract Article PDF–6.9M

Select item 53361458.

Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking

Santiago Lima, Sheldon Milstien, Sarah Spiegel

J Biol Chem. 2017 Feb 24; 292(8): 3074–3088. Published online 2017 Jan 3. doi: 10.1074/jbc.M116.762377

PMCID:: PMC5336145

Abstract Article PDF–6.7M

Select item 51238249.

Sphingosine kinase 1 cooperates with autophagy to maintain endocytic membrane trafficking

Megan M. Young, Yoshinori Takahashi, Todd E. Fox, Jong K. Yun, Mark Kester, Hong-Gang Wang

Cell Rep. Author manuscript; available in PMC 2016 Nov 25.

Published in final edited form as: Cell Rep. 2016 Nov 1; 17(6): 1532–1545. doi: 10.1016/j.celrep.2016.10.019

PMCID:: PMC5123824

Abstract Article PDF–3.4M

Select item 496822610.

SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells

Jose Felix Moruno Manchon, Ndidi-Ese Uzor, Steven Finkbeiner, Andrey S. Tsvetkov

Autophagy. 2016 Aug; 12(8): 1418–1424. Published online 2016 Jul 28. doi: 10.1080/15548627.2016.1183082

PMCID:: PMC4968226

Abstract Article PDF–836K

Select item 456718011.

The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins

Magdalena Cieślik, Grzegorz A. Czapski, Joanna B. Strosznajder

PLoS One. 2015; 10(9): e0137193. Published online 2015 Sep 3. doi: 10.1371/journal.pone.0137193

PMCID:: PMC4567180

Abstract Article PDF–1.9M

Select item 426314412.

Pathological roles of the VEGF/SphK pathway in Niemann–Pick type C neurons

Hyun Lee, Jong Kil Lee, Min Hee Park, Yu Ri Hong, Hugo H. Marti, Hyongbum Kim, Yohei Okada, Makoto Otsu, Eul-Ju Seo, Jae-Hyung Park, Jae-Hoon Bae, Nozomu Okino, Xingxuan He, Edward H. Schuchman, Jae-sung Bae, Hee Kyung Jin

Nat Commun. 2014 Nov 24; 5: 5514. Published online 2014 Nov 24. doi: 10.1038/ncomms6514

PMCID:: PMC4263144

Abstract Article PDF–5.8M

Select item 426111913.

FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway

Min Xu, Dan Liu, Li-hong Ding, Kun-ling Ma, Min Wu, Lin-li Lv, Yi Wen, Hong Liu, Ri-ning Tang, Bi-cheng Liu

Acta Pharmacol Sin. 2014 Dec; 35(12): 1537–1545. Published online 2014 Nov 17. doi: 10.1038/aps.2014.100

PMCID:: PMC4261119

Abstract Article PDF–3.5M

Select item 423089414.

Coupling between endocytosis and sphingosine kinase I recruitment

Hongying Shen, Francesca Giordano, Yumei Wu, Jason Chan, Chen Zhu, Ira Milosevic, Xudong Wu, Kai Yao, Bo Chen, Tobias Baumgart, Derek Sieburth, Pietro De Camilli

Nat Cell Biol. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Nat Cell Biol. 2014 Jul; 16(7): 652–662. Published online 2014 Jun 15. doi: 10.1038/ncb2987