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Select item 111786081.

Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps

Seyedeh Nasim Mirbahari, Nayeralsadat Fatemi, Sanaz Savabkar, Vahid Chaleshi, Neda Zali, Mohammad Yaghoob Taleghani, Ebrahim Mirzaei, Leili Rejali, Pardis Ketabi Moghadam, Ehsan Nazemalhosseini Mojarad

Mol Biol Rep. 2024; 51(1): 764. Published online 2024 Jun 14. doi: 10.1007/s11033-024-09683-3

PMCID:: PMC11178608

Abstract Article PDF–2.9M

Select item 93383132.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 83641813.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 75237064.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 75037485.

Novel Missense CACNA1G Mutations Associated with Infantile-Onset Developmental and Epileptic Encephalopathy

Géza Berecki, Katherine L. Helbig, Tyson L. Ware, Bronwyn Grinton, Cara M. Skraban, Eric D. Marsh, Samuel F. Berkovic, Steven Petrou

Int J Mol Sci. 2020 Sep; 21(17): 6333. Published online 2020 Aug 31. doi: 10.3390/ijms21176333

PMCID:: PMC7503748

Abstract Article PDF–1.6M

Select item 65945516.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 62876787.

Role of individual S4 segments in gating of Ca_v3.1 T-type calcium channel by voltage

Bohumila Jurkovicova-Tarabova, Katarina Mackova, Lucia Moravcikova, Maria Karmazinova, Lubica Lacinova

Channels (Austin) 2018; 12(1): 378–387. Published online 2018 Nov 7. doi: 10.1080/19336950.2018.1543520

PMCID:: PMC6287678

Abstract Article PDF–1.4M

Select item 61713408.

Pharmacogenetics of Antiepileptic Drug Efficacy in Childhood Absence Epilepsy

Tracy A. Glauser, Katherine Holland, Valerie P. O’Brien, Mehdi Keddache, Lisa J. Martin, Peggy O. Clark, Avital Cnaan, Dennis Dlugos, Deborah G Hirtz, Shlomo Shinnar, Gregory Grabowski

Ann Neurol. Author manuscript; available in PMC 2018 Oct 4.

Published in final edited form as: Ann Neurol. 2017 Mar; 81(3): 444–453. doi: 10.1002/ana.24886

PMCID:: PMC6171340

Abstract Article PDF–459K

Select item 59309379.

T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B

Agustin Garcia-Caballero, Fang-Xiong Zhang, Victoria Hodgkinson, Junting Huang, Lina Chen, Ivana A. Souza, Stuart Cain, Jennifer Kass, Sascha Alles, Terrance P. Snutch, Gerald W. Zamponi

Mol Brain. 2018; 11: 24. Published online 2018 May 2. doi: 10.1186/s13041-018-0368-5

PMCID:: PMC5930937

Abstract Article PDF–1.7M

Select item 572399010.

Calmodulin regulates Ca_v3 T-type channels at their gating brake

Jean Chemin, Valentina Taiakina, Arnaud Monteil, Michael Piazza, Wendy Guan, Robert F. Stephens, Ashraf Kitmitto, Zhiping P. Pang, Annette C. Dolphin, Edward Perez-Reyes, Thorsten Dieckmann, Joseph Guy Guillemette, J. David Spafford

J Biol Chem. 2017 Dec 8; 292(49): 20010–20031. Published online 2017 Sep 25. doi: 10.1074/jbc.M117.807925

PMCID:: PMC5723990

Abstract Article PDF–4.2M

Select item 557320411.

Prognostic relevance of a T-type calcium channels gene signature in solid tumours: A correlation ready for clinical validation

Lorenzo Fornaro, Caterina Vivaldi, Dong Lin, Hui Xue, Alfredo Falcone, Yuzhuo Wang, Francesco Crea, Martin D. Bootman

PLoS One. 2017; 12(8): e0182818. Published online 2017 Aug 28. doi: 10.1371/journal.pone.0182818

PMCID:: PMC5573204

Abstract Article PDF–2.7M

Select item 555571412.

Transcriptome analysis of PDGFRα⁺ cells identifies T-type Ca²⁺ channel CACNA1G as a new pathological marker for PDGFRα⁺ cell hyperplasia

Se Eun Ha, Moon Young Lee, Masaaki Kurahashi, Lai Wei, Brian G. Jorgensen, Chanjae Park, Paul J. Park, Doug Redelman, Kent C. Sasse, Laren S. Becker, Kenton M. Sanders, Seungil Ro

PLoS One. 2017; 12(8): e0182265. Published online 2017 Aug 14. doi: 10.1371/journal.pone.0182265

PMCID:: PMC5555714

Abstract Article PDF–47M

Select item 555408913.

Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome

Jeffrey D. Calhoun, Nicole A. Hawkins, Nicole J. Zachwieja, Jennifer A. Kearney

Epilepsia. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Epilepsia. 2017 Aug; 58(8): e111–e115. Published online 2017 May 28. doi: 10.1111/epi.13811

PMCID:: PMC5554089

Abstract Article PDF–557K

Select item 555368214.

A T-type channel-calmodulin complex triggers αCaMKII activation

Hadhimulya Asmara, Ileana Micu, Arsalan P. Rizwan, Giriraj Sahu, Brett A. Simms, Fang-Xiong Zhang, Jordan D. T. Engbers, Peter K. Stys, Gerald W. Zamponi, Ray W. Turner

Mol Brain. 2017; 10: 37. Published online 2017 Aug 11. doi: 10.1186/s13041-017-0317-8

PMCID:: PMC5553682

Abstract Article PDF–2.9M

Select item 537991915.

Evolutionary insights into T-type Ca²⁺ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue

Carolyn L. Smith, Salsabil Abdallah, Yuen Yan Wong, Phuong Le, Alicia N. Harracksingh, Liana Artinian, Arianna N. Tamvacakis, Vincent Rehder, Thomas S. Reese, Adriano Senatore

J Gen Physiol. 2017 Apr 3; 149(4): 483–510. doi: 10.1085/jgp.201611683

PMCID:: PMC5379919

Abstract Article PDF–3.4M

Select item 496100716.

T-type channels: release a brake, engage a gear

Norbert Weiss, Lubica Lacinova

Channels (Austin) 2016 Mar-Apr; 10(2): 78–80. Published online 2015 Oct 21. doi: 10.1080/19336950.2015.1106655

PMCID:: PMC4961007

Article PDF–400K

Select item 469344017.

A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia

Hiroyuki Morino, Yukiko Matsuda, Keiko Muguruma, Ryosuke Miyamoto, Ryosuke Ohsawa, Toshiyuki Ohtake, Reiko Otobe, Masahiko Watanabe, Hirofumi Maruyama, Kouichi Hashimoto, Hideshi Kawakami

Mol Brain. 2015; 8: 89. Published online 2015 Dec 29. doi: 10.1186/s13041-015-0180-4

PMCID:: PMC4693440

Abstract Article PDF–2.0M

Select item 466710518.

A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia

Marie Coutelier, Iulia Blesneac, Arnaud Monteil, Marie-Lorraine Monin, Kunie Ando, Emeline Mundwiller, Alfredo Brusco, Isabelle Le Ber, Mathieu Anheim, Anna Castrioto, Charles Duyckaerts, Alexis Brice, Alexandra Durr, Philippe Lory, Giovanni Stevanin

Am J Hum Genet. 2015 Nov 5; 97(5): 726–737. Published online 2015 Oct 8. doi: 10.1016/j.ajhg.2015.09.007