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Select item 114419841.

Mesenchymal Osr1⁺ cells regulate embryonic lymphatic vessel formation

Pedro Vallecillo-García, Mira Nicola Kühnlein, Mickael Orgeur, Nils Rouven Hansmeier, Georgios Kotsaris, Zarah Gertrud Meisen, Bernd Timmermann, Claudia Giesecke-Thiel, René Hägerling, Sigmar Stricker

Development. 2024 Sep 1; 151(17): dev202747. Published online 2024 Sep 2. doi: 10.1242/dev.202747

PMCID:: PMC11441984

Abstract Article

Select item 112909722.

Meningeal lymphatic CGRP signaling governs pain via cerebrospinal fluid efflux and neuroinflammation in migraine models

Nathan P. Nelson-Maney, László Bálint, Anna L.S. Beeson, D. Stephen Serafin, Bryan M. Kistner, Elizabeth S. Douglas, Aisha H. Siddiqui, Alyssa M. Tauro, Kathleen M. Caron

J Clin Invest. 2024 Aug 1; 134(15): e175616. Published online 2024 May 14. doi: 10.1172/JCI175616

PMCID:: PMC11290972

Abstract Article PDF–14M

Select item 112451533.

Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema

Pascal Brouillard, Aino Murtomäki, Veli-Matti Leppänen, Marko Hyytiäinen, Sandrine Mestre, Lucas Potier, Laurence M. Boon, Nicole Revencu, Arin Greene, Andrey Anisimov, Miia H. Salo, Reetta Hinttala, Lauri Eklund, Isabelle Quéré, Kari Alitalo, Miikka Vikkula

J Clin Invest. 2024 Jul 15; 134(14): e173586. Published online 2024 May 30. doi: 10.1172/JCI173586

PMCID:: PMC11245153

Abstract Article PDF–2.9M

Select item 111589854.

Suppression of VEGFR‐3 signaling inhibits lymph node metastasis in gastric cancer

Kenji Shimizu, Hajime Kubo, Koji Yamaguchi, Kazuhiko Kawashima, Yoshihide Ueda, Koichi Matsuo, Masaaki Awane, Yasuyuki Shimahara, Arimichi Takabayashi, Yoshio Yamaoka, Seiji Satoh

Cancer Sci. 2004 Apr; 95(4): 328–333. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2004.tb03211.x

PMCID:: PMC11158985

Abstract Article PDF–2.2M

Select item 111282085.

Alkali injury–induced pathological lymphangiogenesis in the iris facilitates the infiltration of T cells and ocular inflammation

Zheng Liu, Keli Liu, Shunhua Shi, Xun Chen, Xinyu Gu, Weifa Wang, Keli Mao, Rukeye Yibulayi, Wanwen Wu, Lei Zeng, Weibin Zhou, Xiaofeng Lin, Feng Zhang, Bingsheng Lou

JCI Insight. 2024 Apr 8; 9(7): e175479. Published online 2024 Apr 8. doi: 10.1172/jci.insight.175479

PMCID:: PMC11128208

Abstract Article PDF–17M

Select item 109603386.

The pathological roles and potential mechanisms of vascular endothelial growth factor receptor-3 in gastric cancer

Xiu-Feng Li, Xiu-Juan Zhang, Fu-Rong Hao, Xiao-Tong Dong, Guo-Dong Xu, Yun-Xiang Zhang

J Int Med Res. 2024 Mar; 52(3): 03000605241234558. Published online 2024 Mar 22. doi: 10.1177/03000605241234558

PMCID:: PMC10960338

Abstract Article PDF–1.7M

Select item 108766487.

PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek

Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8

PMCID:: PMC10876648

Abstract Article PDF–10M

Select item 106567108.

Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis

Pengfei Lu, Bingruo Wu, Yidong Wang, Megan Russell, Yang Liu, Daniel J. Bernard, Deyou Zheng, Bin Zhou

Dev Cell. Author manuscript; available in PMC 2023 Nov 18.

Published in final edited form as: Dev Cell. 2023 May 8; 58(9): 791–805.e4. Published online 2023 Apr 5. doi: 10.1016/j.devcel.2023.03.009

PMCID:: PMC10656710

Abstract Article PDF–6.2M

Select item 106296799.

Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development

Molly R. Kulikauskas, Morgan Oatley, Tianji Yu, Ziqing Liu, Lauren Matsumura, Elise Kidder, Dana Ruter, Victoria L. Bautch

Development. 2023 Nov 1; 150(21): dev201811. Published online 2023 Nov 3. doi: 10.1242/dev.201811

PMCID:: PMC10629679

Abstract Article

Select item 1057115910.

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function

Lorenzo M. Fernandes, Jeffrey Tresemer, Jing Zhang, Jonathan J. Rios, Joshua P. Scallan, Michael T. Dellinger

Front Cell Dev Biol. 2023; 11: 1276333. Published online 2023 Sep 25. doi: 10.3389/fcell.2023.1276333

PMCID:: PMC10571159

Abstract Article PDF–14M

Select item 1050377811.

VEGFR3 is required for button junction formation in lymphatic vessels

Melanie Jannaway, Drishya Iyer, Diandra M. Mastrogiacomo, Kunyu Li, Derek C. Sung, Ying Yang, Mark L. Kahn, Joshua P. Scallan

Cell Rep. Author manuscript; available in PMC 2023 Sep 15.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112777. Published online 2023 Jul 16. doi: 10.1016/j.celrep.2023.112777

PMCID:: PMC10503778

Abstract Article PDF–1.5M

Select item 1032807812.

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia–reperfusion injury

Can Tan, Pieter R Norden, Wei Yu, Ting Liu, Naoto Ujiie, Sun Kyong Lee, Xiaocai Yan, Yaryna Dyakiv, Kazushi Aoto, Sagrario Ortega, Isabelle G De Plaen, Venkatesh Sampath, Tsutomu Kume

EMBO Rep. 2023 Jul; 24(7): e56030. Published online 2023 May 8. doi: 10.15252/embr.202256030

PMCID:: PMC10328078

Abstract Article PDF–28M

Select item 1028152613.

Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells

Ryoko Sato-Nishiuchi, Masamichi Doiguchi, Nanami Morooka, Kiyotoshi Sekiguchi

J Cell Biol. 2023 Sep 4; 222(9): e202208047. Published online 2023 Jun 20. doi: 10.1083/jcb.202208047

PMCID:: PMC10281526

Abstract Article PDF–5.2M

Select item 1009797514.

Mechanosensitive mTORC1 signaling maintains lymphatic valves

Cansaran Saygili Demir, Amélie Sabine, Muyun Gong, Olivier Dormond, Tatiana V. Petrova

J Cell Biol. 2023 Jun 5; 222(6): e202207049. Published online 2023 Apr 10. doi: 10.1083/jcb.202207049

PMCID:: PMC10097975

Abstract Article PDF–9.6M

Select item 999720515.

Sinusoidal and lymphatic vessel growth is controlled by reciprocal VEGF-C–CDH5 inhibition

Derek C. Sung, Mei Chen, Martin H. Dominguez, Aparna Mahadevan, Xiaowen Chen, Jisheng Yang, Siqi Gao, Aileen A. Ren, Alan T. Tang, Patricia Mericko, Raiyah Patton, Michelle Lee, Melanie Jannaway, Astrid Nottebaum, Dietmar Vestweber, Joshua P. Scallan, Mark L. Kahn

Nat Cardiovasc Res. Author manuscript; available in PMC 2023 Mar 9.

Published in final edited form as: Nat Cardiovasc Res. 2022 Nov; 1(11): 1006–1021. Published online 2022 Nov 11. doi: 10.1038/s44161-022-00147-0

PMCID:: PMC9997205

Abstract Article PDF–5.6M

Select item 988464016.

Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation

Milena Petkova, Marle Kraft, Simon Stritt, Ines Martinez-Corral, Henrik Ortsäter, Michael Vanlandewijck, Bojana Jakic, Eulàlia Baselga, Sandra D. Castillo, Mariona Graupera, Christer Betsholtz, Taija Mäkinen

J Exp Med. 2023 Apr 3; 220(4): e20220741. Published online 2023 Jan 23. doi: 10.1084/jem.20220741

PMCID:: PMC9884640

Abstract Article PDF–10M

Select item 983623017.

Formation of the glomerular microvasculature is regulated by VEGFR-3

Michael D. Donnan, Dilip K. Deb, Tuncer Onay, Rizaldy P. Scott, Eric Ni, Yalu Zhou, Susan E. Quaggin

Am J Physiol Renal Physiol. 2023 Jan 1; 324(1): F91–F105. Published online 2022 Nov 17. doi: 10.1152/ajprenal.00066.2022

PMCID:: PMC9836230

Abstract Article

Select item 971253618.

Deciphering the heterogeneity of the Lyve1⁺ perivascular macrophages in the mouse brain

C. Siret, M. van Lessen, J. Bavais, H. W. Jeong, S. K. Reddy Samawar, K. Kapupara, S. Wang, M. Simic, L. de Fabritus, A. Tchoghandjian, M. Fallet, H. Huang, S. Sarrazin, M. H. Sieweke, R. Stumm, L. Sorokin, R. H. Adams, S. Schulte-Merker, F. Kiefer, S. A. van de Pavert

Nat Commun. 2022; 13: 7366. Published online 2022 Nov 30. doi: 10.1038/s41467-022-35166-9

PMCID:: PMC9712536

Abstract Article PDF–10M

Select item 965432819.

Tumor-Associated Lymphatics Upregulate MHC-II to Suppress Tumor-Infiltrating Lymphocytes

Claire Y. Li, Hyeung Ju Park, Jinyeon Shin, Jung Eun Baik, Babak J. Mehrara, Raghu P. Kataru

Int J Mol Sci. 2022 Nov; 23(21): 13470. Published online 2022 Nov 3. doi: 10.3390/ijms232113470

PMCID:: PMC9654328

Abstract Article PDF–3.5M

Select item 956016020.

The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse

Kazuaki Maruyama, Sachiko Miyagawa-Tomita, Yuka Haneda, Mayuko Kida, Fumio Matsuzaki, Kyoko Imanaka-Yoshida, Hiroki Kurihara

eLife. 2022; 11: e81515. Published online 2022 Oct 5. doi: 10.7554/eLife.81515

PMCID:: PMC9560160

Abstract Article PDF–39M

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