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Items: 1 to 20 of 129

1.
The modular nature of apoptotic signaling proteins
K. Hofmann
Cell Mol Life Sci. 1999 Jul; 55(8-9): 1113–1128. doi: 10.1007/s000180050361
PMCID:
PMC11146888
AbstractArticlePDF–923K
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Changes in FADD levels, distribution, and phosphorylation in TNFα-induced apoptosis in hepatocytes is caspase-3, caspase-8 and BID dependent
Xiaoying Zhang, Raghuveer Vallabhaneni, Patricia A. Loughran, Richard Shapiro, Xiao-Min Yin, Youzhong Yuan, Timothy R. Billiar
Apoptosis. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Apoptosis. 2008 Aug; 13(8): 983–992. doi: 10.1007/s10495-008-0228-3
PMCID:
PMC9976294
AbstractArticlePDF–1.0M
4.
FADD phosphorylation contributes to development of renal fibrosis by accelerating epithelial-mesenchymal transition
Yan Lin, Fangfang Cai, Xiaoyang Wang, Yunwen Yang, Yongzhe Ren, Chun Yao, Xiaoxing Yin, Hongqin Zhuang, Zichun Hua
Cell Cycle. 2023; 22(5): 580–595. Published online 2022 Oct 24. doi: 10.1080/15384101.2022.2136463
PMCID:
PMC9928456
AbstractArticlePDF–3.7M
5.
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis
Diego A. Rodriguez, Giovanni Quarato, Swantje Liedmann, Bart Tummers, Ting Zhang, Cliff Guy, Jeremy Chase Crawford, Gustavo Palacios, Stephane Pelletier, Halime Kalkavan, Jeremy J. P. Shaw, Patrick Fitzgerald, Mark J. Chen, Siddharth Balachandran, Douglas R. Green
Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2207240119. Published online 2022 Oct 3. doi: 10.1073/pnas.2207240119
PMCID:
PMC9565532
AbstractArticlePDF–2.6M
6.
The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis
Kenta Moriwaki, Christa Park, Kazuha Koyama, Sakthi Balaji, Kohei Kita, Ryoko Yagi, Sachiko Komazawa-Sakon, Manami Semba, Tatsuya Asuka, Hiroyasu Nakano, Yoshihiro Kamada, Eiji Miyoshi, Francis K. M. Chan
Mucosal Immunol. 2022; 15(1): 84–95. Published online 2021 Aug 30. doi: 10.1038/s41385-021-00446-y
PMCID:
PMC8732271
AbstractArticlePDF–8.0M
7.
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells
Jan Wenzel, Josephine Lampe, Helge Müller-Fielitz, Raphael Schuster, Marietta Zille, Kristin Müller, Markus Krohn, Jakob Körbelin, Linlin Zhang, Ümit Özorhan, Vanessa Neve, Julian U. G. Wagner, Denisa Bojkova, Mariana Shumliakivska, Yun Jiang, Anke Fähnrich, Fabian Ott, Valentin Sencio, Cyril Robil, Susanne Pfefferle, Florent Sauve, Caio Fernando Ferreira Coêlho, Jonas Franz, Frauke Spiecker, Beate Lembrich, Sonja Binder, Nina Feller, Peter König, Hauke Busch, Ludovic Collin, Roberto Villaseñor, Olaf Jöhren, Hermann C. Altmeppen, Manolis Pasparakis, Stefanie Dimmeler, Jindrich Cinatl, Klaus Püschel, Matija Zelic, Dimitry Ofengeim, Christine Stadelmann, François Trottein, Ruben Nogueiras, Rolf Hilgenfeld, Markus Glatzel, Vincent Prevot, Markus Schwaninger
Nat Neurosci. 2021; 24(11): 1522–1533. Published online 2021 Oct 21. doi: 10.1038/s41593-021-00926-1
PMCID:
PMC8553622
AbstractArticlePDF–7.6M
8.
OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice
Hannah Schünke, Ulrike Göbel, Ivan Dikic, Manolis Pasparakis
Nat Commun. 2021; 12: 5912. Published online 2021 Oct 8. doi: 10.1038/s41467-021-25945-1
PMCID:
PMC8501112
AbstractArticlePDF–10M
9.
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity
Esther Hoste, Kim Lecomte, Karl Annusver, Niels Vandamme, Jana Roels, Sophia Maschalidi, Lien Verboom, Hanna-Kaisa Vikkula, Mozes Sze, Lisette Van Hove, Kevin Verstaen, Arne Martens, Tino Hochepied, Yvan Saeys, Kodi Ravichandran, Maria Kasper, Geert van Loo
Nat Commun. 2021; 12: 5913. Published online 2021 Oct 8. doi: 10.1038/s41467-021-25944-2
PMCID:
PMC8501048
AbstractArticlePDF–3.9M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression
Dianrong Li, Jie Chen, Jia Guo, Lin Li, Gaihong Cai, She Chen, Jia Huang, Hui Yang, Yinhua Zhuang, Fengchao Wang, Xiaodong Wang
eLife. 2021; 10: e67409. Published online 2021 May 24. doi: 10.7554/eLife.67409
PMCID:
PMC8143796
AbstractArticlePDF–6.2M
12.
Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL
Teodora Oltean, Emily Van San, Tatyana Divert, Tom Vanden Berghe, Xavier Saelens, Jonathan Maelfait, Nozomi Takahashi, Peter Vandenabeele
Cell Death Dis. 2021 May; 12(5): 471. Published online 2021 May 11. doi: 10.1038/s41419-021-03746-0
PMCID:
PMC8113499
AbstractArticlePDF–1.6M
13.
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar, Evan Peter Williams, Lillian Zalduondo, Parimal Samir, Min Zheng, Balamurugan Sundaram, Balaji Banoth, R.K. Subbarao Malireddi, Patrick Schreiner, Geoffrey Neale, Peter Vogel, Richard Webby, Colleen Beth Jonsson, Thirumala-Devi Kanneganti
Cell. 2021 Jan 7; 184(1): 149–168.e17. Published online 2020 Nov 19. doi: 10.1016/j.cell.2020.11.025
PMCID:
PMC7674074
AbstractArticlePDF–9.9M
14.
Caspase-8-dependent inflammatory responses are controlled by its adapter, FADD, and necroptosis
Bart Tummers, Luigi Mari, Clifford S. Guy, Bradlee L. Heckmann, Diego A. Rodriguez, Sebastian Rühl, Julien Moretti, Jeremy Chase Crawford, Patrick Fitzgerald, Thirumala-Devi Kanneganti, Laura J. Janke, Stephane Pelletier, J. Magarian Blander, Douglas R. Green
Immunity. Author manuscript; available in PMC 2021 Jun 16.
Published in final edited form as: Immunity. 2020 Jun 16; 52(6): 994–1006.e8. Published online 2020 May 18. doi: 10.1016/j.immuni.2020.04.010
PMCID:
PMC7306001
AbstractArticlePDF–1.8M
15.
Z-nucleic acid sensing triggers ZBP1-dependent necroptosis and inflammation
Huipeng Jiao, Laurens Wachsmuth, Snehlata Kumari, Robin Schwarzer, Juan Lin, Remzi Onur Eren, Amanda Fisher, Rebecca Lane, George R. Young, George Kassiotis, William J. Kaiser, Manolis Pasparakis
Nature. Author manuscript; available in PMC 2020 Sep 25.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 391–395. Published online 2020 Mar 25. doi: 10.1038/s41586-020-2129-8
Correction in:
Nature. 2020 Apr; 580(7804): E10.
PMCID:
PMC7279955
AbstractArticlePDF–6.0M
16.
MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome
Xixi Zhang, Cunxian Fan, Haiwei Zhang, Qun Zhao, Yongbo Liu, Chengxian Xu, Qun Xie, Xiaoxia Wu, Xianjun Yu, Jianke Zhang, Haibing Zhang
Cell Rep. Author manuscript; available in PMC 2020 Apr 30.
Published in final edited form as: Cell Rep. 2016 Sep 20; 16(12): 3247–3259. Published online 2016 Aug 4. doi: 10.1016/j.celrep.2016.06.103
PMCID:
PMC7191534
AbstractArticlePDF–2.4M
17.
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
R.K. Subbarao Malireddi, Prajwal Gurung, Sannula Kesavardhana, Parimal Samir, Amanda Burton, Harisankeerth Mummareddy, Peter Vogel, Stephane Pelletier, Sandeepta Burgula, Thirumala-Devi Kanneganti
J Exp Med. 2020 Mar 2; 217(3): jem.20191644. Published online 2019 Dec 23. doi: 10.1084/jem.20191644
PMCID:
PMC7062518
AbstractArticlePDF–6.4M
18.
The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain–Fas-associated death domain interaction
Sophia Koutsogiannaki, Lifei Hou, Hasan Babazada, Toshiaki Okuno, Nathan Blazon-Brown, Sulpicio G. Soriano, Takehiko Yokomizo, Koichi Yuki
FASEB J. 2019 Nov; 33(11): 12668–12679. Published online 2019 Nov. doi: 10.1096/fj.201901360R
PMCID:
PMC6988854
AbstractArticle
19.
RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury
Santosh Krishna-Subramanian, Stephan Singer, Marietta Armaka, Jesus M. Banales, Kerstin Holzer, Peter Schirmacher, Henning Walczak, George Kollias, Manolis Pasparakis, Vangelis Kondylis
Cell Death Differ. 2019 Dec; 26(12): 2710–2726. Published online 2019 Apr 15. doi: 10.1038/s41418-019-0330-9
PMCID:
PMC6861136
AbstractArticlePDF–7.1M
20.
Upregulation of the Fas Receptor Death-Inducing Signaling Complex after Traumatic Brain Injury in Mice and Humans
Jianhua Qiu, Michael J. Whalen, Pedro Lowenstein, Gary Fiskum, Brenda Fahy, Ribal Darwish, Bizhan Aarabi, Junying Yuan, Michael A. Moskowitz
J Neurosci. 2002 May 1; 22(9): 3504–3511. doi: 10.1523/JNEUROSCI.22-09-03504.2002
PMCID:
PMC6758354
AbstractArticlePDF–445K

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