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Select item 111505541.

Enhancing ASPP2 promotes acute liver injury via an inflammatory immunoregulatory mechanism

Xiangying Zhang, Ling Xu, Zihao Fan, Yao Gao, Yuan Tian, Yaling Cao, Dexi Chen, Feng Ren

Front Immunol. 2024; 15: 1381735. Published online 2024 May 22. doi: 10.3389/fimmu.2024.1381735

PMCID:: PMC11150554

Abstract Article PDF–2.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 97160973.

Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice

Fang Xie, Hang-fei Xu, Jing Zhang, Xiao-ni Liu, Bu-xin Kou, Meng-yin Cai, Jing Wu, Jin-ling Dong, Qing-hua Meng, Yi Wang, Dexi Chen, Yang Zhang

Front Immunol. 2022; 13: 974872. Published online 2022 Nov 18. doi: 10.3389/fimmu.2022.974872

PMCID:: PMC9716097

Abstract Article PDF–12M

Select item 88546944.

ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas

Nat Commun. 2022; 13: 941. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28590-4

PMCID:: PMC8854694

Abstract Article PDF–15M

Select item 88501955.

Knockout of ASPP2 promotes DEN-induced hepatocarcinogenesis via the NF-κB pathway in mice

Shanshan Wang, Buxin Kou, Mengyin Chai, Yuxue Gao, Xuejun Lin, Ling Yin, Dexi Chen, Xiaoni Liu

Cancer Gene Ther. 2022; 29(2): 202–214. Published online 2021 Feb 8. doi: 10.1038/s41417-021-00300-0

PMCID:: PMC8850195

Abstract Article PDF–4.7M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80988147.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 76112168.

Truncated ASPP2 drives initiation and progression of invasive lobular carcinoma via distinct mechanisms

Koen Schipper, Anne Paulien Drenth, Eline van der Burg, Samuel P. Cornelissen, Sjoerd Klarenbeek, Micha Nethe, Jos Jonkers

Cancer Res. Author manuscript; available in PMC 2021 Jul 12.

Published in final edited form as: Cancer Res. 2020 Apr 1; 80(7): 1486–1497. Published online 2020 Feb 14. doi: 10.1158/0008-5472.CAN-19-3607

PMCID:: PMC7611216

Abstract Article PDF–3.3M

Select item 66313219.

Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins

Robert F. Hennigan, Jonathan S. Fletcher, Steven Guard, Nancy Ratner

Sci Signal. Author manuscript; available in PMC 2019 Oct 23.

Published in final edited form as: Sci Signal. 2019 Apr 23; 12(578): eaau8749. Published online 2019 Apr 23. doi: 10.1126/scisignal.aau8749

PMCID:: PMC6631321

Abstract Article PDF–1.1M

Select item 661912510.

ASPP1/2 Regulate p53-Dependent Death of Retinal Ganglion Cells through PUMA and Fas/CD95 Activation In Vivo

Ariel M. Wilson, Barbara Morquette, Mohamed Abdouh, Nicolás Unsain, Philip A. Barker, Elena Feinstein, Gilbert Bernier, Adriana Di Polo

J Neurosci. 2013 Jan 30; 33(5): 2205–2216. doi: 10.1523/JNEUROSCI.2635-12.2013

PMCID:: PMC6619125

Abstract Article PDF–1.7M

Select item 643367011.

Deficiency of apoptosis‐stimulating protein two of p53 ameliorates acute kidney injury induced by ischemia reperfusion in mice through upregulation of autophagy

Jing Ji, Xiaoshuang Zhou, Ping Xu, Yafeng Li, Honglin Shi, Dexi Chen, Rongshan Li, Hongbo Shi

J Cell Mol Med. 2019 Apr; 23(4): 2457–2467. Published online 2019 Jan 23. doi: 10.1111/jcmm.14094

PMCID:: PMC6433670

Abstract Article PDF–1.4M

Select item 629895812.

Deficiency of apoptosis-stimulating protein two of p53 promotes liver regeneration in mice by activating mammalian target of rapamycin

Hongbo Shi, Yizhi Zhang, Jing Ji, Ping Xu, Honglin Shi, Xiujuan Yue, Feng Ren, Yu Chen, Zhongping Duan, Dexi Chen

Sci Rep. 2018; 8: 17927. Published online 2018 Dec 18. doi: 10.1038/s41598-018-36208-3

PMCID:: PMC6298958

Abstract Article PDF–4.5M

Select item 564508213.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 550974014.

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling

Brent Wilkinson, Jing Li, Marcelo P. Coba

Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3

PMCID:: PMC5509740

Abstract Article PDF–4.6M

Select item 523761315.

ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival

Kathryn Van Hook, Zhiping Wang, Dexi Chen, Casey Nold, Zhiyi Zhu, Pavana Anur, Hun-Joo Lee, Zhiyong Yu, Brett Sheppard, Mu-Shui Dai, Rosalie Sears, Paul Spellman, Charles D. Lopez

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Jan 22.

Published in final edited form as: Biochem Biophys Res Commun. 2017 Jan 22; 482(4): 1271–1277. Published online 2016 Dec 8. doi: 10.1016/j.bbrc.2016.12.027

PMCID:: PMC5237613

Abstract Article PDF–908K

Select item 513648716.

ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome

J Zak, V Vives, D Szumska, A Vernet, J E Schneider, P Miller, E A Slee, S Joss, Y Lacassie, E Chen, L F Escobar, M Tucker, A S Aylsworth, H A Dubbs, A T Collins, J Andrieux, A Dieux-Coeslier, E Haberlandt, D Kotzot, D A Scott, M J Parker, Z Zakaria, Y S Choy, D Wieczorek, A M Innes, K R Jun, S Zinner, F Prin, C A Lygate, P Pretorius, J A Rosenfeld, T J Mohun, X Lu

Cell Death Differ. 2016 Dec; 23(12): 1973–1984. Published online 2016 Jul 22. doi: 10.1038/cdd.2016.76