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Items: 1 to 20 of 27

1.
Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML
Alison E. Meyer, Cary Stelloh, Kirthi Pulakanti, Robert Burns, Joseph B. Fisher, Katelyn E. Heimbruch, Sergey Tarima, Quinlan Furumo, John Brennan, Yongwei Zheng, Aaron D. Viny, George S. Vassiliou, Sridhar Rao
Leukemia. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Leukemia. 2022 Aug; 36(8): 2032–2041. Published online 2022 Jul 1. doi: 10.1038/s41375-022-01632-y
PMCID:
PMC9357218
AbstractArticlePDF–1.8M
2.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
3.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
4.
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles
Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel, Tilman Brummer
Oncotarget. 2016 May 3; 7(18): 26628–26652. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8427
PMCID:
PMC5042004
AbstractArticlePDF–7.5M
5.
DOCK180 Is a Rac Activator That Regulates Cardiovascular Development by Acting Downstream of CXCR4
Fumiyuki Sanematsu, Masanori Hirashima, Mélanie Laurin, Ryosuke Takii, Akihiko Nishikimi, Keiko Kitajima, Guo Ding, Mamiko Noda, Yuzo Murata, Yoshihiko Tanaka, Sadahiko Masuko, Toshio Suda, Chikara Meno, Jean-François Côté, Takashi Nagasawa, Yoshinori Fukui
Circ Res. Author manuscript; available in PMC 2015 Nov 10.
Published in final edited form as: Circ Res. 2010 Oct 29; 107(9): 1102–1105. Published online 2010 Sep 9. doi: 10.1161/CIRCRESAHA.110.223388
PMCID:
PMC4640903
AbstractArticlePDF–924K
6.
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo
Nature. Author manuscript; available in PMC 2015 Nov 28.
Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269
PMCID:
PMC4617540
AbstractArticlePDF–518K
7.
Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling
H Bagci, M Laurin, J Huber, W J Muller, J-F Côté
Cell Death Dis. 2014 Aug; 5(8): e1375. Published online 2014 Aug 14. doi: 10.1038/cddis.2014.338
PMCID:
PMC4454313
AbstractArticlePDF–5.6M
8.
The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo
Mélanie Laurin, Annie Dumouchel, Yoshinori Fukui, Jean-François Côté
Small GTPases. 2013 Oct 1; 4(4): 221–230. Published online 2013 Dec 23. doi: 10.4161/sgtp.27430
PMCID:
PMC4011817
AbstractArticlePDF–2.0M
9.
Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis
Mélanie Laurin, Jennifer Huber, Ariane Pelletier, Tarek Houalla, Morag Park, Yoshinori Fukui, Benjamin Haibe-Kains, William J. Muller, Jean-François Côté
Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18): 7434–7439. Published online 2013 Apr 16. doi: 10.1073/pnas.1213050110
PMCID:
PMC3645577
AbstractArticlePDF–1020K
10.
Phosphatidic Acid-dependent Recruitment and Function of the Rac Activator DOCK1 during Dorsal Ruffle Formation
Fumiyuki Sanematsu, Akihiko Nishikimi, Mayuki Watanabe, Tsunaki Hongu, Yoshihiko Tanaka, Yasunori Kanaho, Jean-François Côté, Yoshinori Fukui
J Biol Chem. 2013 Mar 22; 288(12): 8092–8100. Published online 2013 Jan 29. doi: 10.1074/jbc.M112.410423
PMCID:
PMC3605628
AbstractArticlePDF–2.1M
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusion
Therese B. Deramaudt, Denis Dujardin, Abdelkader Hamadi, Fanny Noulet, Kaouther Kolli, Jan De Mey, Kenneth Takeda, Philippe Rondé
Mol Biol Cell. 2011 Apr 1; 22(7): 964–975. doi: 10.1091/mbc.E10-08-0725
PMCID:
PMC3069021
AbstractArticlePDF–9.7M
13.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
14.
Rac1 Is Essential for Basement Membrane-Dependent Epiblast Survival
Xiaowen He, Jie Liu, Yanmei Qi, Cord Brakebusch, Anna Chrostek-Grashoff, David Edgar, Peter D. Yurchenco, Siobhan A. Corbett, Stephen F. Lowry, Alan M. Graham, Yaling Han, Shaohua Li
Mol Cell Biol. 2010 Jul; 30(14): 3569–3581. Published online 2010 May 10. doi: 10.1128/MCB.01366-09
PMCID:
PMC2897552
AbstractArticlePDF–3.8M
15.
Structural and Functional Basis of a Role for CRKL in a Fibroblast Growth Factor 8-Induced Feed-Forward Loop
Ji-Heui Seo, Atsushi Suenaga, Mariko Hatakeyama, Makoto Taiji, Akira Imamoto
Mol Cell Biol. 2009 Jun; 29(11): 3076–3087. Published online 2009 Mar 23. doi: 10.1128/MCB.01686-08
PMCID:
PMC2681998
AbstractArticlePDF–3.2M
16.
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo
Mélanie Laurin, Nadine Fradet, Anne Blangy, Alan Hall, Kristiina Vuori, Jean-François Côté
Proc Natl Acad Sci U S A. 2008 Oct 7; 105(40): 15446–15451. Published online 2008 Sep 26. doi: 10.1073/pnas.0805546105
PMCID:
PMC2563090
AbstractArticlePDF–1.4M
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
18.
Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling
Xiaoling Li, Xue Gao, Guofa Liu, Wencheng Xiong, Jane Wu, Yi Rao
Nat Neurosci. Author manuscript; available in PMC 2008 Mar 5.
Published in final edited form as: Nat Neurosci. 2008 Jan; 11(1): 28–35. Published online 2007 Dec 9. doi: 10.1038/nn2022
PMCID:
PMC2262939
AbstractArticlePDF–794K
19.
The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration
Stephen J. Pratt, Holly Epple, Michael Ward, Yunfeng Feng, Vania M. Braga, Gregory D. Longmore
J Cell Biol. 2005 Feb 28; 168(5): 813–824. doi: 10.1083/jcb.200406083
PMCID:
PMC2171823
AbstractArticlePDF–4.8M
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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