PMC Links for GEO Profiles (Select 118645873) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109002724.

Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8⁺T cell function and its impact against pancreatic ductal adenocarcinoma

Wei Wei, Linqing Tian, Xiaoyan Zheng, Lei Zhong, Yuan Chen, Hui Dong, Guibing Zhang, Shibing Wang, Xiangmin Tong

Oncoimmunology. 2024; 13(1): 2322173. Published online 2024 Feb 27. doi: 10.1080/2162402X.2024.2322173

PMCID:: PMC10900272

Abstract Article PDF–7.5M

Select item 108711525.

Modulation of sarcopenia phenotypes by glutathione peroxidase 4 overexpression in mice

Hongyang Xu, Agnieszka Czyżowska, Holly Van Remmen, Jacob L. Brown

J Physiol. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: J Physiol. 2023 Dec; 601(23): 5277–5293. Published online 2023 Oct 25. doi: 10.1113/JP285259

PMCID:: PMC10871152

Abstract Article PDF–1.7M

Select item 107775726.

Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice

Xue Bai, Bing Wang, Yiduo Cui, Siqi Tian, Yi Zhang, Linhao You, Yan-Zhong Chang, Guofen Gao

J Neuroinflammation. 2024; 21: 15. Published online 2024 Jan 9. doi: 10.1186/s12974-023-03008-0

PMCID:: PMC10777572

Abstract Article PDF–8.2M

Select item 107701207.

FUNDC1 interacts with GPx4 to govern hepatic ferroptosis and fibrotic injury through a mitophagy-dependent manner

Yaguang Bi, Shuolin Liu, Xing Qin, Miyesaier Abudureyimu, Lu Wang, Rongjun Zou, Amir Ajoolabady, Wenjing Zhang, Hu Peng, Jun Ren, Yingmei Zhang

J Adv Res. 2024 Jan; 55: 45–60. Published online 2023 Feb 23. doi: 10.1016/j.jare.2023.02.012

PMCID:: PMC10770120

Abstract Article PDF–5.8M

Select item 106386108.

HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression

Lijun Zhang, Fang Chen, Jian Dong, Rong Wang, Guangyu Bi, Daoliang Xu, Yingwei Zhang, Yijun Deng, Wenjun Lin, Zhongzhou Yang, Wangsen Cao

Redox Biol. 2023 Dec; 68: 102939. Published online 2023 Oct 20. doi: 10.1016/j.redox.2023.102939

PMCID:: PMC10638610

Abstract Article PDF–18M

Select item 103451399.

GPX4 is a key ferroptosis biomarker and correlated with immune cell populations and immune checkpoints in childhood sepsis

Guoxin Qu, Hui Liu, Jin Li, Siyuan Huang, Nannan Zhao, Ling Zeng, Jin Deng

Sci Rep. 2023; 13: 11358. Published online 2023 Jul 13. doi: 10.1038/s41598-023-32992-9

PMCID:: PMC10345139

Abstract Article PDF–11M

Select item 1027614310.

Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness

Agnieszka Czyżowska, Jacob Brown, Hongyang Xu, Kavitha Sataranatarajan, Michael Kinter, Victoria J. Tyrell, Valerie B. O'Donnell, Holly Van Remmen

Redox Biol. 2023 Aug; 64: 102761. Published online 2023 Jun 1. doi: 10.1016/j.redox.2023.102761

PMCID:: PMC10276143

Abstract Article PDF–11M

Select item 981133011.

GPX4 deficiency-dependent phospholipid peroxidation drives motor deficits of ALS

Long-Fang Tu, Tian-Ze Zhang, Yang-Fan Zhou, Qing-Qing Zhou, Hai-Biao Gong, Lei Liang, Lin-Na Hai, Nan-Xin You, Yang Su, Yong-Jun Chen, Xu-Kai Mo, Chang-Zheng Shi, Liang-Ping Luo, Wan-Yang Sun, Wen-Jun Duan, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He

J Adv Res. 2023 Jan; 43: 205–218. Published online 2022 Mar 4. doi: 10.1016/j.jare.2022.02.016

PMCID:: PMC9811330

Abstract Article PDF–4.2M

Select item 980408112.

Netrin‐1 upregulates GPX4 and prevents ferroptosis after traumatic brain injury via the UNC5B/Nrf2 signaling pathway

Yuanda Zhang, Jin Lan, Dongxu Zhao, Cijie Ruan, Jue Zhou, Haoyuan Tan, Yinghui Bao

CNS Neurosci Ther. 2023 Jan; 29(1): 216–227. Published online 2022 Dec 5. doi: 10.1111/cns.13997

PMCID:: PMC9804081

Abstract Article PDF–14M

Select item 979540913.

Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair

Shintaro Ide, Kana Ide, Koki Abe, Yoshihiko Kobayashi, Hiroki Kitai, Jennifer McKey, Sarah A. Strausser, Lori L. O’Brien, Aleksandra Tata, Purushothama Rao Tata, Tomokazu Souma

Cell Rep. Author manuscript; available in PMC 2022 Dec 28.

Published in final edited form as: Cell Rep. 2022 Nov 8; 41(6): 111610. doi: 10.1016/j.celrep.2022.111610

PMCID:: PMC9795409

Abstract Article PDF–3.1M

Select item 971225314.

The role of selenoproteins in neutrophils during inflammation

Tai-Jung Lee, Shaneice K. Nettleford, Allison McGlynn, Bradley A. Carlson, Girish S. Kirimanjeswara, K. Sandeep Prabhu

Arch Biochem Biophys. Author manuscript; available in PMC 2023 Dec 15.

Published in final edited form as: Arch Biochem Biophys. 2022 Dec 15; 732: 109452. Published online 2022 Nov 3. doi: 10.1016/j.abb.2022.109452

PMCID:: PMC9712253

Abstract Article PDF–821K

Select item 963748415.

Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx

Shaoyi Wang, Weiwei Li, Pengfei Zhang, Zihao Wang, Xiaoyuan Ma, Chuanju Liu, Krasimir Vasilev, Lei Zhang, Xiaocong Zhou, Liang Liu, John Hayball, Shuli Dong, Yuhua Li, Yuan Gao, Lei Cheng, Yunpeng Zhao

J Adv Res. 2022 Nov; 41: 63–75. Published online 2022 Jan 11. doi: 10.1016/j.jare.2022.01.004

PMCID:: PMC9637484

Abstract Article PDF–5.3M

Select item 945847116.

GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection

Eduardo P. Amaral, Taylor W. Foreman, Sivaranjani Namasivayam, Kerry L. Hilligan, Keith D. Kauffman, Caio Cesar Barbosa Bomfim, Diego L. Costa, Beatriz Barreto-Duarte, Clarissa Gurgel-Rocha, Monique Freire Santana, Marcelo Cordeiro-Santos, Elsa Du Bruyn, Catherine Riou, Kate Aberman, Robert John Wilkinson, Daniel L. Barber, Katrin D. Mayer-Barber, Bruno B. Andrade, Alan Sher

J Exp Med. 2022 Nov 7; 219(11): e20220504. Published online 2022 Sep 7. doi: 10.1084/jem.20220504

PMCID:: PMC9458471

Abstract Article PDF–7.5M

Select item 945619517.

Unbalanced Expression of Glutathione Peroxidase 4 and Arachidonate 15-Lipoxygenase Affects Acrosome Reaction and In Vitro Fertilization

Mariana Soria-Tiedemann, Geert Michel, Iris Urban, Maceler Aldrovandi, Valerie B. O’Donnell, Sabine Stehling, Hartmut Kuhn, Astrid Borchert

Int J Mol Sci. 2022 Sep; 23(17): 9907. Published online 2022 Aug 31. doi: 10.3390/ijms23179907

PMCID:: PMC9456195

Abstract Article PDF–3.0M

Select item 940243218.

A non-canonical vitamin K cycle is a potent ferroptosis suppressor

Eikan Mishima, Junya Ito, Zijun Wu, Toshitaka Nakamura, Adam Wahida, Sebastian Doll, Wulf Tonnus, Palina Nepachalovich, Elke Eggenhofer, Maceler Aldrovandi, Bernhard Henkelmann, Ken-ichi Yamada, Jonas Wanninger, Omkar Zilka, Emiko Sato, Regina Feederle, Daniela Hass, Adriano Maida, André Santos Dias Mourão, Andreas Linkermann, Edward K. Geissler, Kiyotaka Nakagawa, Takaaki Abe, Maria Fedorova, Bettina Proneth, Derek A. Pratt, Marcus Conrad

Nature. 2022; 608(7924): 778–783. Published online 2022 Aug 3. doi: 10.1038/s41586-022-05022-3

PMCID:: PMC9402432

Abstract Article PDF–9.5M

Select item 934601419.

MicroRNA-214-3p aggravates ferroptosis by targeting GPX4 in cisplatin-induced acute kidney injury

Junran Zhou, Chengcheng Xiao, Shuaishuai Zheng, Qian Wang, Hai Zhu, Yingyu Zhang, Renhe Wang

Cell Stress Chaperones. 2022 Jul; 27(4): 325–336. Published online 2022 Apr 2. doi: 10.1007/s12192-022-01271-3

PMCID:: PMC9346014

Abstract Article PDF–2.4M

Select item 934225620.

Methyltransferase-like 3 silenced inhibited the ferroptosis development via regulating the glutathione peroxidase 4 levels in the intracerebral hemorrhage progression

Liu Zhang, Xiangyu Wang, Wenqiang Che, Yongjun Yi, Shuoming Zhou, Yongjian Feng

Bioengineered. 2022; 13(6): 14215–14226. Published online 2022 Jun 25. doi: 10.1080/21655979.2022.2084494

PMCID:: PMC9342256

Abstract Article PDF–10M

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