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Items: 1 to 20 of 66

1.
Inhibitory functions of PD-L1 and PD-L2 in the regulation of anti-tumor immunity in murine tumor microenvironment
Daisuke Umezu, Nana Okada, Yukimi Sakoda, Keishi Adachi, Toshiyasu Ojima, Hiroki Yamaue, Masatoshi Eto, Koji Tamada
Cancer Immunol Immunother. 2019 Feb; 68(2): 201–211. Published online 2018 Oct 24. doi: 10.1007/s00262-018-2263-4
PMCID:
PMC11028338
AbstractArticlePDF–960K
2.
Pan-cancer analysis identifies PD-L2 as a tumor promotor in the tumor microenvironment
Jingfang Lv, Zheng Jiang, Junhu Yuan, Meng Zhuang, Xu Guan, Hengchang Liu, Yefeng Yin, Yiming Ma, Zheng Liu, Hongying Wang, Xishan Wang
Front Immunol. 2023; 14: 1093716. Published online 2023 Mar 16. doi: 10.3389/fimmu.2023.1093716
PMCID:
PMC10060638
AbstractArticlePDF–15M
3.
PD-L2 controls peripherally induced regulatory T cells by maintaining metabolic activity and Foxp3 stability
Benjamin P. Hurrell, Doumet Georges Helou, Emily Howard, Jacob D. Painter, Pedram Shafiei-Jahani, Arlene H. Sharpe, Omid Akbari
Nat Commun. 2022; 13: 5118. Published online 2022 Aug 31. doi: 10.1038/s41467-022-32899-5
PMCID:
PMC9433378
AbstractArticlePDF–2.4M
4.
PD-L2 glycosylation promotes immune evasion and predicts anti-EGFR efficacy
Yiqi Xu, Zhenyue Gao, Ruxin Hu, Yuqing Wang, Yuhong Wang, Zheng Su, Xiaoyue Zhang, Jingxuan Yang, Mei Mei, Yu Ren, Min Li, Xuan Zhou
J Immunother Cancer. 2021; 9(10): e002699. Published online 2021 Oct 25. doi: 10.1136/jitc-2021-002699
PMCID:
PMC8547513
AbstractArticlePDF–4.4M
5.
L2pB1 Cells Contribute to Tumor Growth Inhibition
Varuna Shibad, Ali Bootwala, Changchuin Mao, Hanna Bader, Hung Vo, Esther Landesman-Bollag, Conrad Guo, Angel Rubio, Richard Near, Wenda Gao, Sreekar Challa, Vennela Chukka, Jeffrey Gao, Avery Kelly, Tamar Landesman, Tyler VanHelene, Xuemei Zhong
Front Immunol. 2021; 12: 722451. Published online 2021 Sep 23. doi: 10.3389/fimmu.2021.722451
PMCID:
PMC8495424
AbstractArticlePDF–16M
6.
Lung-resident memory B cells protect against bacterial pneumonia
Kimberly A. Barker, Neelou S. Etesami, Anukul T. Shenoy, Emad I. Arafa, Carolina Lyon de Ana, Nicole M.S. Smith, Ian M.C. Martin, Wesley N. Goltry, Alexander M.S. Barron, Jeffrey L. Browning, Hasmeena Kathuria, Anna C. Belkina, Antoine Guillon, Xuemei Zhong, Nicholas A. Crossland, Matthew R. Jones, Lee J. Quinton, Joseph P. Mizgerd
J Clin Invest. 2021 Jun 1; 131(11): e141810. Published online 2021 Jun 1. doi: 10.1172/JCI141810
PMCID:
PMC8159694
AbstractArticlePDF–2.2M
7.
The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection
Kristen E. Pauken, Jernej Godec, Pamela M. Odorizzi, Keturah E. Brown, Kathleen B. Yates, Shin Foong Ngiow, Kelly P. Burke, Seth Maleri, Shannon M. Grande, Loise M. Francisco, Mohammed-Alkhatim Ali, Sabrina Imam, Gordon J. Freeman, W. Nicholas Haining, E. John Wherry, Arlene H. Sharpe
Cell Rep. Author manuscript; available in PMC 2020 Jul 23.
Published in final edited form as: Cell Rep. 2020 Jun 30; 31(13): 107827. doi: 10.1016/j.celrep.2020.107827
PMCID:
PMC7377452
AbstractArticlePDF–2.4M
8.
A novel role for programmed cell death receptor ligand 2 in sepsis-induced hepatic dysfunction
Anne-Lise Rossi, Marilyn Le, Chun-Shiang Chung, Yaping Chen, Eleanor A. Fallon, Andres Matoso, Shumin Xu, Tristen T. Chun, Craig P. Erickson, Alfred Ayala
Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1; 316(1): G106–G114. Published online 2018 Nov 15. doi: 10.1152/ajpgi.00204.2018
PMCID:
PMC6383374
AbstractArticle
9.
B7-DC (PD-L2) costimulation of CD4+ T-helper 1 response via RGMb
Xinxin Nie, Wenni Chen, Ying Zhu, Baozhu Huang, Weiwei Yu, Zhanshuai Wu, Sizheng Guo, Yiping Zhu, Liqun Luo, Shengdian Wang, Lieping Chen
Cell Mol Immunol. 2018 Oct; 15(10): 888–897. Published online 2017 May 8. doi: 10.1038/cmi.2017.17
PMCID:
PMC6207567
AbstractArticlePDF–4.2M
10.
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Shabnam Shalapour, Xue-Jia Lin, Ingmar N. Bastian, John Brain, Alastair D. Burt, Alexander A. Aksenov, Alison F. Vrbanac, Weihua Li, Andres Perkins, Takaji Matsutani, Zhenyu Zhong, Debanjan Dhar, Jose A. Navas-Molina, Jun Xu, Rohit Loomba, Michael Downes, Ruth T. Yu, Ronald M. Evans, Pieter C. Dorrestein, Rob Knight, Christopher Benner, Quentin M. Anstee, Michael Karin
Nature. Author manuscript; available in PMC 2018 May 16.
Published in final edited form as: Nature. 2017 Nov 16; 551(7680): 340–345. Published online 2017 Nov 8. doi: 10.1038/nature24302
Correction in:
Nature. 2017 Dec 21; 552(7685): 430.
Correction in:
Nature. 2018 Sep; 561(7721): E1.
PMCID:
PMC5884449
AbstractArticlePDF–5.3M
11.
PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-vs-Host Disease
Kathryn W Juchem, Faruk Sacirbegovic, Cuiling Zhang, Arlene H. Sharpe, Kerry Russell, Jennifer M. McNiff, Anthony J. Demetris, Mark J Shlomchik, Warren D Shlomchik
J Immunol. Author manuscript; available in PMC 2019 Jan 15.
Published in final edited form as: J Immunol. 2018 Jan 15; 200(2): 834–846. Published online 2017 Dec 6. doi: 10.4049/jimmunol.1701076
PMCID:
PMC5760452
AbstractArticlePDF–1.5M
12.
PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients
Mohammad S. Hossain, Ghada M. Kunter, Vicky F. El-Najjar, David L. Jaye, Zaid Al-Kadhimi, Owonikoko K. Taofeek, Jian-Ming Li, Edmund K. Waller
PLoS One. 2017; 12(9): e0184254. Published online 2017 Sep 27. doi: 10.1371/journal.pone.0184254
PMCID:
PMC5617147
AbstractArticlePDF–6.3M
13.
PD-L2 regulates B-1 cell antibody production against phosphorylcholine through an IL-5–dependent mechanism
Jerome T. McKay, Marcela A. Haro, Christina A. Daly, Rama D. Yammani, Bing Pang, W. Edward Swords, Karen M. Haas
J Immunol. Author manuscript; available in PMC 2018 Sep 15.
Published in final edited form as: J Immunol. 2017 Sep 15; 199(6): 2020–2029. Published online 2017 Aug 2. doi: 10.4049/jimmunol.1700555
PMCID:
PMC5587397
AbstractArticlePDF–981K
14.
PD-L1/PD-L2-expressing B-1 cells inhibit alloreactive T cells in mice
Takayuki Hirose, Yuka Tanaka, Asuka Tanaka, Hiroshi Sakai, Yu Sasaki, Nobuo Shinohara, Hideki Ohdan
PLoS One. 2017; 12(6): e0178765. Published online 2017 Jun 1. doi: 10.1371/journal.pone.0178765
PMCID:
PMC5453578
AbstractArticlePDF–18M
15.
PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso, Martin W. LaFleur, Natalie Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe
J Exp Med. 2017 Apr 3; 214(4): 895–904. doi: 10.1084/jem.20160801
PMCID:
PMC5379970
AbstractArticlePDF–1.4M
16.
PD-L2 negatively regulates Th1-mediated immunopathology during Fasciola hepatica infection
Cinthia C. Stempin, Claudia C. Motrán, María P. Aoki, Cristian R. Falcón, Fabio M. Cerbán, Laura Cervi
Oncotarget. 2016 Nov 22; 7(47): 77721–77731. Published online 2016 Oct 21. doi: 10.18632/oncotarget.12790
PMCID:
PMC5363616
AbstractArticlePDF–3.9M
17.
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality
Asim Saha, Roddy S. O’Connor, Govindarajan Thangavelu, Scott B. Lovitch, Durga Bhavani Dandamudi, Caleph B. Wilson, Benjamin G. Vincent, Victor Tkachev, Jan M. Pawlicki, Scott N. Furlan, Leslie S. Kean, Kazutoshi Aoyama, Patricia A. Taylor, Angela Panoskaltsis-Mortari, Rocio Foncea, Parvathi Ranganathan, Steven M. Devine, Joel S. Burrill, Lili Guo, Catarina Sacristan, Nathaniel W. Snyder, Ian A. Blair, Michael C. Milone, Michael L. Dustin, James L. Riley, David A. Bernlohr, William J. Murphy, Brian T. Fife, David H. Munn, Jeffrey S. Miller, Jonathan S. Serody, Gordon J. Freeman, Arlene H. Sharpe, Laurence A. Turka, Bruce R. Blazar
J Clin Invest. 2016 Jul 1; 126(7): 2642–2660. Published online 2016 Jun 13. doi: 10.1172/JCI85796
PMCID:
PMC4922691
AbstractArticlePDF–4.1M
18.
Costimulator B7-DC Attenuates Strong Th2 Responses Induced by Nippostrongylus brasiliensis
Kenji Ishiwata, Naohiro Watanabe, Miao Guo, Kei Tomihara, Michael J. Brumlik, Hideo Yagita, Drew Pardoll, Lieping Chen, Tahiro Shin
J Immunol. Author manuscript; available in PMC 2016 May 10.
Published in final edited form as: J Immunol. 2010 Feb 15; 184(4): 2086–2094. Published online 2010 Jan 11. doi: 10.4049/jimmunol.0804051
PMCID:
PMC4862405
AbstractArticlePDF–3.2M
19.
Fluorescence tagging and inducible depletion of PD-L2–expressing B-1 B cells in vivo
Rebecca Lee, Changchuin Mao, Hung Vo, Wenda Gao, Xuemei Zhong
Ann N Y Acad Sci. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: Ann N Y Acad Sci. 2015 Dec; 1362(1): 77–85. Published online 2015 Aug 20. doi: 10.1111/nyas.12865
PMCID:
PMC4679664
AbstractArticlePDF–329K
20.
Immunosuppressive plasma cells impede T cell-dependent immunogenic chemotherapy
Shabnam Shalapour, Joan Font-Burgada, Giuseppe Di Caro, Zhenyu Zhong, Elsa Sanchez-Lopez, Debanjan Dhar, Gerald Willimsky, Massimo Ammirante, Amy Strasner, Donna E. Hansel, Christina Jamieson, Christopher J. Kane, Tobias Klatte, Peter Birner, Lukas Kenner, Michael Karin
Nature. Author manuscript; available in PMC 2015 Nov 7.
Published in final edited form as: Nature. 2015 May 7; 521(7550): 94–98. Published online 2015 Apr 29. doi: 10.1038/nature14395
PMCID:
PMC4501632
AbstractArticlePDF–3.7M

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