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Items: 1 to 20 of 56

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
SOCS2 regulation of growth hormone signaling requires a canonical interaction with phosphotyrosine
Kunlun Li, Lizeth G. Meza Guzman, Lachlan Whitehead, Evelyn Leong, Andrew Kueh, Warren S. Alexander, Nadia J. Kershaw, Jeffrey J. Babon, Karen Doggett, Sandra E. Nicholson
Biosci Rep. 2022 Dec 22; 42(12): BSR20221683. Published online 2022 Dec 9. doi: 10.1042/BSR20221683
PMCID:
PMC9742514
AbstractArticlePDF–4.3M
3.
Epigenetic downregulation of Socs2 contributes to mutant N-Ras-mediated hematopoietic dysregulation
Xi Jin, Victor Ng, Meiling Zhao, Lu Liu, Tomoyasu Higashimoto, Zheng Hong Lee, Jooho Chung, Victor Chen, Gina Ney, Malathi Kandarpa, Moshe Talpaz, Qing Li
Dis Model Mech. 2022 May 1; 15(5): dmm049088. Published online 2022 May 6. doi: 10.1242/dmm.049088
PMCID:
PMC9092650
AbstractArticle
4.
CircHivep2 contributes to microglia activation and inflammation via miR‐181a‐5p/SOCS2 signalling in mice with kainic acid‐induced epileptic seizures
Gao Xiaoying, Mian Guo, Liu Jie, Zhu Yanmei, Cui Ying, Shu Shengjie, Gou Haiyan, Sun Feixiang, Qi Sihua, Sun Jiahang
J Cell Mol Med. 2020 Nov; 24(22): 12980–12993. Published online 2020 Oct 1. doi: 10.1111/jcmm.15894
PMCID:
PMC7701587
AbstractArticlePDF–1.4M
5.
SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes
Tiantian Zhang, Yizhe Chen, Jiarui Cai, Miao Pan, Qian Sun, Jing Zhang, Chao Sun
Oxid Med Cell Longev. 2020; 2020: 3742542. Published online 2020 Jul 13. doi: 10.1155/2020/3742542
PMCID:
PMC7376435
AbstractArticlePDF–3.8M
6.
KIAA0317 regulates pulmonary inflammation through SOCS2 degradation
Travis B. Lear, Alison C. McKelvey, John W. Evankovich, Shristi Rajbhandari, Tiffany A. Coon, Sarah R. Dunn, James D. Londino, Bryan J. McVerry, Yingze Zhang, Eleanor Valenzi, Christine L. Burton, Rachael Gordon, Sebastien Gingras, Karina C. Lockwood, Michael J. Jurczak, Robert Lafyatis, Mark J. Shlomchik, Yuan Liu, Bill B. Chen
JCI Insight. 2019 Oct 3; 4(19): e129110. Published online 2019 Oct 3. doi: 10.1172/jci.insight.129110
PMCID:
PMC6795399
AbstractArticlePDF–50M
7.
Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells
Lu Liu, Meiling Zhao, Xi Jin, Gina Ney, Kevin B Yang, Fanglue Peng, Jin Cao, Takao Iwawaki, Juan Del Valle, Xi Chen, Qing Li
Nat Cell Biol. Author manuscript; available in PMC 2019 Sep 16.
Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 328–337. Published online 2019 Feb 18. doi: 10.1038/s41556-019-0285-6
PMCID:
PMC6745703
AbstractArticlePDF–1.1M
8.
Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification
Qingquan Zhang, Ru Huang, Youqiong Ye, Xiaoxia Guo, Jun Lu, Fugui Zhu, Xiaohui Gong, Qitong Zhang, Jie Yan, Lina Luo, Shaowei Zhuang, Yihan Chen, Xiaodong Zhao, Sylvia M. Evans, Cizhong Jiang, Xingqun Liang, Yunfu Sun
Cell Death Dis. 2018 Feb; 9(2): 247. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0283-9
PMCID:
PMC5833373
AbstractArticlePDF–4.6M
9.
Suppressor of cytokine signaling 2 (Socs2) deletion protects bone health of mice with DSS-induced inflammatory bowel disease
Ross Dobie, Vicky E. MacRae, Chloe Pass, Elspeth M. Milne, S. Faisal Ahmed, Colin Farquharson
Dis Model Mech. 2018 Jan 1; 11(1): dmm028456. doi: 10.1242/dmm.028456
PMCID:
PMC5818069
AbstractArticle
10.
RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion
Corinne L. Fairchild, Keiko Hino, Jisoo S. Han, Adam M. Miltner, Gabriel Peinado Allina, Caileigh E. Brown, Marie E. Burns, Anna La Torre, Sergi Simó
Development. 2018 Feb 1; 145(3): dev155283. doi: 10.1242/dev.155283
PMCID:
PMC5817999
AbstractArticle
11.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development
Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon
Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112
PMCID:
PMC5611955
AbstractArticle
12.
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment
Christopher J. Nirschl, Mayte Suárez-Fariñas, Benjamin Izar, Sanjay Prakadan, Ruth Dannenfelser, Itay Tirosh, Yong Liu, Qian Zhu, K. Sanjana P. Devi, Shaina L. Carroll, David Chau, Melika Rezaee, Tae-Gyun Kim, Ruiqi Huang, Judilyn Fuentes-Duculan, George X. Song-Zhao, Nicholas Gulati, Michelle A. Lowes, Sandra L. King, Francisco J. Quintana, Young-suk Lee, James G. Krueger, Kavita Y. Sarin, Charles H. Yoon, Levi Garraway, Aviv Regev, Alex K. Shalek, Olga Troyanskaya, Niroshana Anandasabapathy
Cell. Author manuscript; available in PMC 2018 Jun 29.
Published in final edited form as: Cell. 2017 Jun 29; 170(1): 127–141.e15. doi: 10.1016/j.cell.2017.06.016
PMCID:
PMC5569303
AbstractArticlePDF–1.2M
13.
Suppressor of cytokine signaling 2 (SOCS2) associates with FLT3 and negatively regulates downstream signaling
Julhash U. Kazi, Lars Rönnstrand
Mol Oncol. 2013 Jun; 7(3): 693–703. Published online 2013 Mar 19. doi: 10.1016/j.molonc.2013.02.020
PMCID:
PMC5528470
AbstractArticlePDF–3.4M
14.
Suppressor of Cytokine Signaling 2 Negatively Regulates NK Cell Differentiation by Inhibiting JAK2 Activity
Won Sam Kim, Mi Jeong Kim, Dong Oh Kim, Jae-Eun Byun, Hangsak Huy, Hae Young Song, Young-Jun Park, Tae-Don Kim, Suk Ran Yoon, Eun-Ji Choi, Haiyoung Jung, Inpyo Choi
Sci Rep. 2017; 7: 46153. Published online 2017 Apr 6. doi: 10.1038/srep46153
PMCID:
PMC5382670
AbstractArticlePDF–1.6M
15.
Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5
Xianke Zeng, Michaela Willi, Ha Youn Shin, Lothar Hennighausen, Chaochen Wang
Cell Rep. Author manuscript; available in PMC 2017 Jan 6.
Published in final edited form as: Cell Rep. 2016 Dec 20; 17(12): 3333–3346. doi: 10.1016/j.celrep.2016.11.079
PMCID:
PMC5217531
AbstractArticlePDF–1.7M
16.
Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF‐1
Ross Dobie, Syed F. Ahmed, Katherine A. Staines, Chloe Pass, Seema Jasim, Vicky E. MacRae, Colin Farquharson
J Cell Physiol. 2015 Nov; 230(11): 2796–2806. Published online 2015 Jul 27. doi: 10.1002/jcp.25006
PMCID:
PMC4949688
AbstractArticlePDF–1.5M
17.
SOCS2 Balances Metabolic and Restorative Requirements during Liver Regeneration
Ryota Masuzaki, Sophia Zhao, M. Todd Valerius, Daisuke Tsugawa, Yuki Oya, Kevin C. Ray, Seth J. Karp
J Biol Chem. 2016 Feb 12; 291(7): 3346–3358. Published online 2015 Dec 23. doi: 10.1074/jbc.M115.703264
PMCID:
PMC4751379
AbstractArticlePDF–3.4M
18.
The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells
John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft
Immunity. Author manuscript; available in PMC 2016 Oct 20.
Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017
PMCID:
PMC4618086
AbstractArticlePDF–2.2M
19.
Direct stimulation of bone mass by increased GH signalling in the osteoblasts of Socs2−/− mice
R Dobie, V E MacRae, C Huesa, R van't Hof, S F Ahmed, C Farquharson
J Endocrinol. 2014 Oct; 223(1): 93–106. Prepublished online 2014 Jul 29. doi: 10.1530/JOE-14-0292
PMCID:
PMC4166176
AbstractArticlePDF–447K
20.
The molecular regulation of Janus kinase (JAK) activation
Jeffrey J. Babon, Isabelle S Lucet, James M Murphy, Nicos A Nicola, Leila N Varghese
Biochem J. Author manuscript; available in PMC 2015 Aug 15.
Published in final edited form as: Biochem J. 2014 Aug 15; 462(1): 1–13. doi: 10.1042/BJ20140712
PMCID:
PMC4112375
AbstractArticlePDF–579K

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