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Select item 110041851.

DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells

Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A. Flavell, Zhanju Liu, Mingsong Li, Wen Pan, Shu Zhu

Nat Commun. 2024; 15: 3080. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47235-2

PMCID:: PMC11004185

Abstract Article PDF–11M

Select item 108145792.

PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic Transformation

Agnes Fütterer, Sara Rodriguez-Acebes, Juan Méndez, Julio Gutiérrez, Carlos Martínez-A

Cells. 2024 Jan; 13(2): 159. Published online 2024 Jan 15. doi: 10.3390/cells13020159

PMCID:: PMC10814579

Abstract Article PDF–10M

Select item 106721663.

Mature mRNA processing that deletes 3′ end sequences directs translational activation and embryonic development

Yuki Takada, Ludivine Fierro, Keisuke Sato, Takahiro Sanada, Anna Ishii, Takehiro Yamamoto, Tomoya Kotani

Sci Adv. 2023 Nov 24; 9(47): eadg6532. Published online 2023 Nov 24. doi: 10.1126/sciadv.adg6532

PMCID:: PMC10672166

Abstract Article PDF–2.2M

Select item 105678264.

DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages

Ning Huangfu, Hongchuang Ma, Mengyun Tian, Jie Zhang, Yong Wang, Zhenwei Li, Xiaomin Chen, Hanbin Cui

Inflammation. 2023; 46(5): 1725–1738. Published online 2023 Jun 16. doi: 10.1007/s10753-023-01836-z

PMCID:: PMC10567826

Abstract Article PDF–3.5M

Select item 104321485.

Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease

Daniel G. Calame, Tianyu Guo, Chen Wang, Lillian Garrett, Angad Jolly, Moez Dawood, Alina Kurolap, Noa Zunz Henig, Jawid M. Fatih, Isabella Herman, Haowei Du, Tadahiro Mitani, Lore Becker, Birgit Rathkolb, Raffaele Gerlini, Claudia Seisenberger, Susan Marschall, Jill V. Hunter, Amanda Gerard, Alexis Heidlebaugh, Thomas Challman, Rebecca C. Spillmann, Shalini N. Jhangiani, Zeynep Coban-Akdemir, Seema Lalani, Lingxiao Liu, Anya Revah-Politi, Alejandro Iglesias, Edwin Guzman, Evan Baugh, Nathalie Boddaert, Sophie Rondeau, Clothide Ormieres, Giulia Barcia, Queenie K.G. Tan, Isabelle Thiffault, Tomi Pastinen, Kazim Sheikh, Suur Biliciler, Davide Mei, Federico Melani, Vandana Shashi, Yuval Yaron, Mary Steele, Emma Wakeling, Elsebet Østergaard, Lusine Nazaryan-Petersen, Undiagnosed Diseases Network, Francisca Millan, Teresa Santiago-Sim, Julien Thevenon, Ange-Line Bruel, Christel Thauvin-Robinet, Denny Popp, Konrad Platzer, Pawel Gawlinski, Wojciech Wiszniewski, Dana Marafi, Davut Pehlivan, Jennifer E. Posey, Richard A. Gibbs, Valerie Gailus-Durner, Renzo Guerrini, Helmut Fuchs, Martin Hrabě de Angelis, Sabine M. Hölter, Hoi-Hung Cheung, Shen Gu, James R. Lupski

Am J Hum Genet. 2023 Aug 3; 110(8): 1394–1413. Published online 2023 Jul 18. doi: 10.1016/j.ajhg.2023.06.013

PMCID:: PMC10432148

Abstract Article PDF–4.2M

Select item 103078526.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 98976717.

Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes

Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Mingsong Li, Richard A. Flavell, Shu Zhu

Sci Adv. 2023 Feb; 9(5): eadd5005. Published online 2023 Feb 3. doi: 10.1126/sciadv.add5005

PMCID:: PMC9897671

Abstract Article PDF–1.8M

Select item 96038608.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 92038519.

Cytosolic Nuclear Sensor Dhx9 Controls Medullary Thymic Epithelial Cell Differentiation by p53-Mediated Pathways

Xue Dong, Jiayu Zhang, Qian Zhang, Zhanfeng Liang, Yanan Xu, Yong Zhao, Baojun Zhang

Front Immunol. 2022; 13: 896472. Published online 2022 Jun 3. doi: 10.3389/fimmu.2022.896472

PMCID:: PMC9203851

Abstract Article PDF–7.2M

Select item 882765410.

DExD/H-box helicase 9 intrinsically controls CD8⁺ T cell–mediated antiviral response through noncanonical mechanisms

Anjun Jiao, Chenming Sun, Xin Wang, Lei Lei, Haiyan Liu, Wenhui Li, Xiaofeng Yang, Huiqiang Zheng, Renyi Ding, Kun Zhu, Yanhong Su, Cangang Zhang, Lianjun Zhang, Baojun Zhang

Sci Adv. 2022 Feb; 8(6): eabk2691. Published online 2022 Feb 9. doi: 10.1126/sciadv.abk2691

PMCID:: PMC8827654

Abstract Article PDF–6.1M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 669277012.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 633346013.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 624418314.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 615862215.

A DNA-sensing–independent role of a nuclear RNA helicase, DHX9, in stimulation of NF-κB–mediated innate immunity against DNA virus infection

Yee Ching Ng, Woo-Chang Chung, Hye-Ri Kang, Hye-Jeong Cho, Eun-Byeol Park, Suk-Jo Kang, Moon Jung Song

Nucleic Acids Res. 2018 Sep 28; 46(17): 9011–9026. Published online 2018 Aug 20. doi: 10.1093/nar/gky742

PMCID:: PMC6158622

Abstract Article PDF–5.7M

Select item 578737516.

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

Shu Zhu, Siyuan Ding, Penghua Wang, Zheng Wei, Wen Pan, Noah W Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Yujiao Zhao, Kellie A. Jurado, Ningguo Feng, Liang Shan, Yuval Kluger, Jun Lu, Clara Abraham, Erol Fikrig, Harry B. Greenberg, Richard A. Flavell

Nature. Author manuscript; available in PMC 2018 Jan 28.

Published in final edited form as: Nature. 2017 Jun 29; 546(7660): 667–670. Published online 2017 Jun 21. doi: 10.1038/nature22967

PMCID:: PMC5787375

Abstract Article PDF–1.5M

Select item 546738917.

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction

Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II

Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076

PMCID:: PMC5467389

Abstract Article PDF–3.2M

Select item 545817718.

Dependence of p53-deficient cells on the DHX9 DExH-box helicase

Teresa Lee, Jerry Pelletier

Oncotarget. 2017 May 9; 8(19): 30908–30921. Published online 2017 Mar 3. doi: 10.18632/oncotarget.15889

PMCID:: PMC5458177

Abstract Article PDF–7.6M

Select item 538122619.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 502345320.

Tumor Cell Survival Dependence on the DHX9 DExH-Box Helicase

Teresa Lee, Marilène Paquet, Ola Larsson, Jerry Pelletier

Oncogene. Author manuscript; available in PMC 2016 Sep 30.

Published in final edited form as: Oncogene. 2016 Sep 29; 35(39): 5093–5105. Published online 2016 Mar 14. doi: 10.1038/onc.2016.52

PMCID:: PMC5023453

Abstract Article PDF–4.7M

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