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Items: 1 to 20 of 22

1.
HILPDA promotes NASH-driven HCC development by restraining intracellular fatty acid flux in hypoxia
Davide Povero, Yongbin Chen, Scott M. Johnson, Cailin E. McMahon, Meixia Pan, Hanmei Bao, Xuan-Mai T. Petterson, Emily Blake, Kimberly P. Lauer, Daniel R. O’Brien, Yue Yu, Rondell P. Graham, Timucin Taner, Xianlin Han, Gina L. Razidlo, Jun Liu
J Hepatol. Author manuscript; available in PMC 2024 Jul 11.
Published in final edited form as: J Hepatol. 2023 Aug; 79(2): 378–393. Published online 2023 Apr 13. doi: 10.1016/j.jhep.2023.03.041
PMCID:
PMC11238876
AbstractArticlePDF–3.6M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
HILPDA is a lipotoxic marker in adipocytes that mediates the autocrine negative feedback regulation of triglyceride hydrolysis by fatty acids and alleviates cellular lipotoxic stress
Lei Deng, Shuangcheng Alivia Wu, Ling Qi, Sander Kersten
Mol Metab. 2023 Sep; 75: 101773. Published online 2023 Jul 6. doi: 10.1016/j.molmet.2023.101773
PMCID:
PMC10391665
AbstractArticlePDF–3.9M
4.
Lipid-Laden Lung Mesenchymal Cells Foster Breast Cancer Metastasis via Metabolic Reprogramming of Tumor Cells and Natural Killer Cells
Zheng Gong, Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren
Cell Metab. Author manuscript; available in PMC 2023 Dec 6.
Published in final edited form as: Cell Metab. 2022 Dec 6; 34(12): 1960–1976.e9. doi: 10.1016/j.cmet.2022.11.003
PMCID:
PMC9819197
AbstractArticlePDF–3.2M
5.
Lipid droplet storage promotes murine pancreatic tumor growth
Jeremy J. Grachan, Martin Kery, Amato J. Giaccia, Nicholas C. Denko, Ioanna Papandreou
Oncol Rep. 2021 Apr; 45(4): 21. Published online 2021 Feb 9. doi: 10.3892/or.2021.7972
PMCID:
PMC8889526
AbstractArticlePDF–532K
6.
Norepinephrine promotes triglyceride storage in macrophages via beta2‐adrenergic receptor activation
Kasparas Petkevicius, Guillaume Bidault, Sam Virtue, Benjamin Jenkins, Xanthe A. M. H. van Dierendonck, Aurelien Dugourd, Julio Saez‐Rodriguez, Rinke Stienstra, Albert Koulman, Antonio Vidal‐Puig
FASEB J. 2021 Feb; 35(2): e21266. Published online 2021 Jan 23. doi: 10.1096/fj.202001101R
PMCID:
PMC7898725
AbstractArticlePDF–1.5M
7.
Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis
Peishan Li, Ming Lu, Jiayuan Shi, Zheng Gong, Li Hua, Qing Li, Bora Lim, Xiang H.-F. Zhang, Xiaowen Chen, Sheng Li, Leonard D. Shultz, Guangwen Ren
Nat Immunol. Author manuscript; available in PMC 2021 Mar 21.
Published in final edited form as: Nat Immunol. 2020 Nov; 21(11): 1444–1455. Published online 2020 Sep 21. doi: 10.1038/s41590-020-0783-5
PMCID:
PMC7584447
AbstractArticlePDF–5.8M
8.
Mitochondrial complex II regulates a distinct oxygen sensing mechanism in monocytes
Shraddha Sharma, Jianming Wang, Eduardo Cortes Gomez, Robert T. Taggart, Bora E. Baysal
Hum Mol Genet. 2017 Apr 1; 26(7): 1328–1339. Published online 2017 Feb 13. doi: 10.1093/hmg/ddx041
PMCID:
PMC6074833
AbstractArticlePDF–810K
9.
Stress-responsive HILPDA is necessary for thermoregulation during fasting
Matthew J. VandeKopple, Jinghai Wu, Lisa A. Baer, Naresh C. Bal, Santosh K. Maurya, Anuradha Kalyanasundaram, Muthu Periasamy, Kristin I. Stanford, Amato J. Giaccia, Nicholas C. Denko, Ioanna Papandreou
J Endocrinol. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: J Endocrinol. 2017 Oct; 235(1): 27–38. Published online 2017 Jul 24. doi: 10.1530/JOE-17-0289
PMCID:
PMC5567683
AbstractArticlePDF–1.3M
10.
Hypoxia-Inducible Lipid Droplet–Associated Is Not a Direct Physiological Regulator of Lipolysis in Adipose Tissue
Wieneke Dijk, Frits Mattijssen, Montserrat de la Rosa Rodriguez, Angel Loza Valdes, Anne Loft, Susanne Mandrup, Eric Kalkhoven, Ling Qi, Jan Willem Borst, Sander Kersten
Endocrinology. 2017 May 1; 158(5): 1231–1251. Published online 2017 Mar 17. doi: 10.1210/en.2016-1809
PMCID:
PMC5460841
AbstractArticle
11.
Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance
Marina T. DiStefano, Rachel J. Roth Flach, Ozlem Senol-Cosar, Laura V. Danai, Joseph V. Virbasius, Sarah M. Nicoloro, Juerg Straubhaar, Sezin Dagdeviren, Martin Wabitsch, Olga T. Gupta, Jason K. Kim, Michael P. Czech
Mol Metab. 2016 Dec; 5(12): 1149–1161. Published online 2016 Sep 28. doi: 10.1016/j.molmet.2016.09.009
PMCID:
PMC5123203
AbstractArticlePDF–2.8M
12.
The Lipid Droplet Protein Hypoxia-inducible Gene 2 Promotes Hepatic Triglyceride Deposition by Inhibiting Lipolysis
Marina T. DiStefano, Laura V. Danai, Rachel J. Roth Flach, Anil Chawla, David J. Pedersen, Adilson Guilherme, Michael P. Czech
J Biol Chem. 2015 Jun 12; 290(24): 15175–15184. Published online 2015 Apr 28. doi: 10.1074/jbc.M115.650184
PMCID:
PMC4463459
AbstractArticlePDF–2.0M
13.
Hypoxia-inducible Lipid Droplet-associated (HILPDA) Is a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Involved in Hepatic Triglyceride Secretion
Frits Mattijssen, Anastasia Georgiadi, Tresty Andasarie, Ewa Szalowska, Annika Zota, Anja Krones-Herzig, Christoph Heier, Dariusz Ratman, Karolien De Bosscher, Ling Qi, Rudolf Zechner, Stephan Herzig, Sander Kersten
J Biol Chem. 2014 Jul 11; 289(28): 19279–19293. Published online 2014 May 29. doi: 10.1074/jbc.M114.570044
PMCID:
PMC4094041
AbstractArticlePDF–3.3M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
17.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
18.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
19.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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