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Select item 114945001.

The transcription factor Sox4 is required for thymic tuft cell development

Nanami Mino, Ryunosuke Muro, Ayami Ota, Sachiko Nitta, Veronique Lefebvre, Takeshi Nitta, Keishi Fujio, Hiroshi Takayanagi

Int Immunol. 2020 Jan; 34(1): 45–52. Published online 2021 Oct 23. doi: 10.1093/intimm/dxab098

PMCID:: PMC11494500

Abstract Article PDF–3.7M

Select item 98895022.

Mature B cells and mesenchymal stem cells control emergency myelopoiesis

Vivian Y Lim, Xing Feng, Runfeng Miao, Sandra Zehentmeier, Nathan Ewing-Crystal, Moonyoung Lee, Alexei V Tumanov, Ji Eun Oh, Akiko Iwasaki, Andrew Wang, Jungmin Choi, João P Pereira

Life Sci Alliance. 2023 Apr; 6(4): e202301924. Published online 2023 Jan 30. doi: 10.26508/lsa.202301924

PMCID:: PMC9889502

Abstract Article PDF–1.8M

Select item 96146843.

Dysregulated stem cell niches and altered lymphocyte recirculation cause B and T cell lymphopenia in WHIM syndrome

Sandra Zehentmeier, Vivian Y. Lim, Yifan Ma, Julia Fossati, Takeshi Ito, Yawen Jiang, Alexei V. Tumanov, Ho-Joon Lee, Lukas Dillinger, Jihyun Kim, Krisztian Csomos, Jolan E. Walter, Jungmin Choi, João P. Pereira

Sci Immunol. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Sci Immunol. 2022 Sep 23; 7(75): eabo3170. Published online 2022 Sep 23. doi: 10.1126/sciimmunol.abo3170

PMCID:: PMC9614684

Abstract Article PDF–1.6M

Select item 94813944.

CREB1 Transcriptionally Activates LTBR to Promote the NF-κB Pathway and Apoptosis in Lung Epithelial Cells

Zhengyun Hu, Guoping Zhou

Comput Math Methods Med. 2022; 2022: 9588740. Published online 2022 Sep 9. doi: 10.1155/2022/9588740

PMCID:: PMC9481394

Abstract Article PDF–3.0M

Select item 94624755.

Treg suppression of immunity within inflamed allogeneic grafts

Hehua Dai, Andressa Pena, Lynne Bauer, Amanda Williams, Simon C. Watkins, Geoffrey Camirand

JCI Insight. 2022 Aug 22; 7(16): e160579. Published online 2022 Aug 22. doi: 10.1172/jci.insight.160579

PMCID:: PMC9462475

Abstract Article PDF–7.9M

Select item 93520966.

LTβR overexpression promotes plasma cell accumulation

Jessica A. Kotov, Ying Xu, Nicholas D. Carey, Jason G. Cyster

PLoS One. 2022; 17(8): e0270907. Published online 2022 Aug 4. doi: 10.1371/journal.pone.0270907

PMCID:: PMC9352096

Abstract Article PDF–2.9M

Select item 90930527.

Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses

Vikas Saxena, Wenji Piao, Lushen Li, Christina Paluskievicz, Yanbao Xiong, Thomas Simon, Ram Lakhan, C. Colin Brinkman, Sarah Walden, Keli L. Hippen, Marina WillsonShirkey, Young S. Lee, Chelsea Wagner, Bruce R. Blazar, Jonathan S. Bromberg

Cell Rep. Author manuscript; available in PMC 2022 May 11.

Published in final edited form as: Cell Rep. 2022 Apr 19; 39(3): 110727. doi: 10.1016/j.celrep.2022.110727

PMCID:: PMC9093052

Abstract Article PDF–2.4M

Select item 90188198.

Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function

Hung-Wei Cheng, Urs Mörbe, Mechthild Lütge, Céline Engetschwiler, Lucas Onder, Mario Novkovic, Cristina Gil-Cruz, Christian Perez-Shibayama, Thomas Hehlgans, Elke Scandella, Burkhard Ludewig

Nat Commun. 2022; 13: 2027. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29734-2

PMCID:: PMC9018819

Abstract Article PDF–3.4M

Select item 87841619.

CD169⁺ macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling

Abdouramane Camara, Alice C. Lavanant, Jun Abe, Henri Lee Desforges, Yannick O. Alexandre, Erika Girardi, Zinaida Igamberdieva, Kenichi Asano, Masato Tanaka, Thomas Hehlgans, Klaus Pfeffer, Sébastien Pfeffer, Scott N. Mueller, Jens V. Stein, Christopher G. Mueller

Proc Natl Acad Sci U S A. 2022 Jan 18; 119(3): e2108540119. Published online 2022 Jan 14. doi: 10.1073/pnas.2108540119

PMCID:: PMC8784161

Abstract Article PDF–2.7M

Select item 856731310.

Lymphocyte access to lymphoma is impaired by high endothelial venule regression

Lutz Menzel, Maria Zschummel, Tadhg Crowley, Vedran Franke, Michael Grau, Carolin Ulbricht, Anja Hauser, Volker Siffrin, Marc Bajénoff, Sophie E. Acton, Altuna Akalin, Georg Lenz, Gerald Willimsky, Uta E. Höpken, Armin Rehm

Cell Rep. 2021 Oct 26; 37(4): 109878. Published online 2021 Oct 26. doi: 10.1016/j.celrep.2021.109878

PMCID:: PMC8567313

Abstract Article

Select item 832084811.

Redefining the Role of Lymphotoxin Beta Receptor in the Maintenance of Lymphoid Organs and Immune Cell Homeostasis in Adulthood

Yajun Shou, Ekaterina Koroleva, Cody M. Spencer, Sergey A. Shein, Anna A. Korchagina, Kizil A. Yusoof, Raksha Parthasarathy, Elizabeth A. Leadbetter, Armen N. Akopian, Amanda R. Muñoz, Alexei V. Tumanov

Front Immunol. 2021; 12: 712632. Published online 2021 Jul 15. doi: 10.3389/fimmu.2021.712632

PMCID:: PMC8320848

Abstract Article PDF–3.5M

Select item 831615212.

Lymphotoxin β Receptor: a Crucial Role in Innate and Adaptive Immune Responses against Toxoplasma gondii

Anne Tersteegen, Ursula R. Sorg, Richard Virgen-Slane, Marcel Helle, Patrick Petzsch, Ildiko R. Dunay, Karl Köhrer, Daniel Degrandi, Carl F. Ware, Klaus Pfeffer

Infect Immun. 2021 Jun; 89(6): e00026-21. Prepublished online 2021 Mar 22. Published online 2021 May 17. doi: 10.1128/IAI.00026-21

PMCID:: PMC8316152

Abstract Article PDF–2.2M

Select item 788721213.

LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells

S. S. Höpner, Ana Raykova, R. Radpour, M. A. Amrein, D. Koller, G. M. Baerlocher, C. Riether, A. F. Ochsenbein

Nat Commun. 2021; 12: 1065. Published online 2021 Feb 16. doi: 10.1038/s41467-021-21317-x

PMCID:: PMC7887212

Abstract Article PDF–5.2M

Select item 771829714.

Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung

Thomas M. Conlon, Gerrit John-Schuster, Danijela Heide, Dominik Pfister, Mareike Lehmann, Yan Hu, Zeynep Ertüz, Martin A. Lopez, Meshal Ansari, Maximilian Strunz, Christoph Mayr, Chiara Ciminieri, Rita Costa, Marlene Sophia Kohlhepp, Adrien Guillot, Gizem Günes, Aicha Jeridi, Maja C. Funk, Giorgi Beroshvili, Sandra Prokosch, Jenny Hetzer, Stijn E. Verleden, Hani Alsafadi, Michael Lindner, Gerald Burgstaller, Lore Becker, Martin Irmler, Michael Dudek, Jakob Janzen, Eric Goffin, Reinoud Gosens, Percy Knolle, Bernard Pirotte, Tobias Stoeger, Johannes Beckers, Darcy Wagner, Indrabahadur Singh, Fabian J. Theis, Martin Hrabé de Angelis, Tracy O O’Connor, Frank Tacke, Michael Boutros, Emmanuel Dejardin, Oliver Eickelberg, Herbert B. Schiller, Melanie Königshoff, Mathias Heikenwalder, Ali Önder Yildirim

Nature. Author manuscript; available in PMC 2021 May 4.

Published in final edited form as: Nature. 2020 Dec; 588(7836): 151–156. Published online 2020 Nov 4. doi: 10.1038/s41586-020-2882-8

Correction in:: Nature. 2020 Dec 22

PMCID:: PMC7718297

Abstract Article PDF–7.2M

Select item 761047715.

Remodeling of light and dark zone follicular dendritic cells governs germinal center responses

Natalia B Pikor, Urs Mörbe, Mechthild Lütge, Cristina Gil-Cruz, Christian Perez-Shibayama, Mario Novkovic, Hung-Wei Cheng, César Nombela-Arrieta, Takashi Nagasawa, Michelle A Linterman, Lucas Onder, Burkhard Ludewig

Nat Immunol. Author manuscript; available in PMC 2021 Mar 29.

Published in final edited form as: Nat Immunol. 2020 Jun 1; 21(6): 649–659. Published online 2020 May 18. doi: 10.1038/s41590-020-0672-y

PMCID:: PMC7610477

Abstract Article PDF–8.8M

Select item 719850016.

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

Beth Lucas, Andrea J. White, Emilie J. Cosway, Sonia M. Parnell, Kieran D. James, Nick D. Jones, Izumi Ohigashi, Yousuke Takahama, William E. Jenkinson, Graham Anderson

Nat Commun. 2020; 11: 2198. Published online 2020 May 4. doi: 10.1038/s41467-020-16041-x

PMCID:: PMC7198500

Abstract Article PDF–3.3M

Select item 711118217.

Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity

Qian Chai, Lucas Onder, Elke Scandella, Cristina Gil-Cruz, Christian Perez-Shibayama, Jovana Cupovic, Renzo Danuser, Tim Sparwasser, Sanjiv A. Luther, Volker Thiel, Thomas Rülicke, Jens V. Stein, Thomas Hehlgans, Burkhard Ludewig

Immunity. 2013 May 23; 38(5): 1013–1024. Published online 2013 Apr 25. doi: 10.1016/j.immuni.2013.03.012

PMCID:: PMC7111182

Abstract Article PDF–4.3M

Select item 698120018.

YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells

Sung Yong Choi, Hosung Bae, Sun-Hye Jeong, Intae Park, Hyunsoo Cho, Seon Pyo Hong, Da-Hye Lee, Choong-kun Lee, Jin-Sung Park, Sang Heon Suh, Jeongwoon Choi, Myung Jin Yang, Jeon Yeob Jang, Lucas Onder, Jeong Hwan Moon, Han-Sin Jeong, Ralf H. Adams, Jin-Man Kim, Burkhard Ludewig, Joo-Hye Song, Dae-Sik Lim, Gou Young Koh

Nat Commun. 2020; 11: 519. Published online 2020 Jan 24. doi: 10.1038/s41467-020-14293-1

PMCID:: PMC6981200

Abstract Article PDF–5.9M

Select item 667262119.

Lymphotoxin β Receptor (LtβR): Dual Roles in Demyelination and Remyelination and Successful Therapeutic Intervention Using LtβR–Ig Protein

Sheila R. Plant, Heather A. Iocca, Ying Wang, J. Cameron Thrash, Brian P. O'Connor, Heather A. Arnett, Yang-Xin Fu, Monica J. Carson, Jenny P.-Y. Ting

J Neurosci. 2007 Jul 11; 27(28): 7429–7437. doi: 10.1523/JNEUROSCI.1307-07.2007

PMCID:: PMC6672621

Abstract Article PDF–495K

Select item 646536720.

Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

Hung-Wei Cheng, Lucas Onder, Mario Novkovic, Charlotte Soneson, Mechthild Lütge, Natalia Pikor, Elke Scandella, Mark D. Robinson, Jun-ichi Miyazaki, Anne Tersteegen, Ursula Sorg, Klaus Pfeffer, Thomas Rülicke, Thomas Hehlgans, Burkhard Ludewig

Nat Commun. 2019; 10: 1739. Published online 2019 Apr 15. doi: 10.1038/s41467-019-09728-3

PMCID:: PMC6465367

Abstract Article PDF–8.3M

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