PMC Links for GEO Profiles (Select 11826799) - PMC

Satadru K. Lahiri, Ann P. Quick, Benoit Samson-Couterie, Mohit Hulsurkar, Ies Elzenaar, Gunnar Weninger, Stephan E. Lehnart, Ralph J. van Oort, Xander H.T. Wehrens

Basic Res Cardiol. Author manuscript; available in PMC 2023 Apr 19.

Published in final edited form as: Basic Res Cardiol. 2020 Jun 26; 115(4): 49. Published online 2020 Jun 26. doi: 10.1007/s00395-020-0807-1

PMCID:: PMC10113426

Abstract Article PDF–1.8M

Select item 99748974.

Reduction in Junctophilin 2 Expression in Cardiac Nodal Tissue Results in Intracellular Calcium-driven Increase in Nodal Cell Automaticity

Andrew P. Landstrom, Qixin Yang, Bo Sun, Robin M. Perelli, Minu-Tshyeto Bidzimou, Zhushan Zhang, Yuriana Aguilar-Sanchez, Katherina M. Alsina, Shuyi Cao, Julia O. Reynolds, Tarah A. Word, Niels M.R. van der Sangen, Quinn Wells, Prince J. Kannankeril, Andreas Ludwig, Jeffrey J. Kim, Xander H.T. Wehrens

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2023 Feb; 16(2): e010858. Published online 2023 Jan 27. doi: 10.1161/CIRCEP.122.010858

PMCID:: PMC9974897

Abstract Article PDF–1.3M

Select item 78204335.

SERCA2a ameliorates cardiomyocyte T-tubule remodeling via the calpain/JPH2 pathway to improve cardiac function in myocardial ischemia/reperfusion mice

Shuai Wang, You Zhou, Yuanyuan Luo, Rongsheng Kan, Jingwen Chen, Haochen Xuan, Chaofan Wang, Junhong Chen, Tongda Xu, Dongye Li

Sci Rep. 2021; 11: 2037. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81570-4

PMCID:: PMC7820433

Abstract Article PDF–4.6M

Select item 77100166.

Differential physiological roles for BIN1 isoforms in skeletal muscle development, function and regeneration

Ivana Prokic, Belinda S. Cowling, Candice Kutchukian, Christine Kretz, Hichem Tasfaout, Vincent Gache, Josiane Hergueux, Olivia Wendling, Arnaud Ferry, Anne Toussaint, Christos Gavriilidis, Vasugi Nattarayan, Catherine Koch, Jeanne Lainé, Roy Combe, Laurent Tiret, Vincent Jacquemond, Fanny Pilot-Storck, Jocelyn Laporte

Dis Model Mech. 2020 Nov 1; 13(11): dmm044354. Published online 2020 Nov 24. doi: 10.1242/dmm.044354

PMCID:: PMC7710016

Abstract Article

Select item 68151357.

Nanoscale coupling of junctophilin-2 and ryanodine receptors regulates vascular smooth muscle cell contractility

Harry A. T. Pritchard, Caoimhin S. Griffin, Evan Yamasaki, Pratish Thakore, Conor Lane, Adam S. Greenstein, Scott Earley

Proc Natl Acad Sci U S A. 2019 Oct 22; 116(43): 21874–21881. Published online 2019 Oct 7. doi: 10.1073/pnas.1911304116

PMCID:: PMC6815135

Abstract Article PDF–1.3M

Select item 66290978.

Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis

Sören Brandenburg, Jan Pawlowitz, Benjamin Eikenbusch, Jonas Peper, Tobias Kohl, Gyuzel Y. Mitronova, Samuel Sossalla, Gerd Hasenfuss, Xander H.T. Wehrens, Peter Kohl, Eva A. Rog-Zielinska, Stephan E. Lehnart

JCI Insight. 2019 Jun 20; 4(12): e127116. Published online 2019 Jun 20. doi: 10.1172/jci.insight.127116

PMCID:: PMC6629097

Abstract Article PDF–17M

Select item 64425759.

RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure

Jing Hu, Chen Gao, Chaoliang Wei, Yuanchao Xue, Changwei Shao, Yajing Hao, Lan-Tao Gou, Yu Zhou, Jianlin Zhang, Shuxun Ren, Ju Chen, Yibin Wang, Xiang-Dong Fu

Proc Natl Acad Sci U S A. 2019 Mar 26; 116(13): 6172–6180. Published online 2019 Mar 13. doi: 10.1073/pnas.1822176116

PMCID:: PMC6442575

Abstract Article PDF–1.7M

Select item 633667710.

E-C coupling structural protein junctophilin-2 encodes a stress-adaptive transcription regulator

Ang Guo, Yihui Wang, Biyi Chen, Yunhao Wang, Jinxiang Yuan, Liyang Zhang, Duane Hall, Jennifer Wu, Yun Shi, Qi Zhu, Cheng Chen, William H. Thiel, Xin Zhan, Robert M. Weiss, Fenghuang Zhan, Catherine A. Musselman, Miles Pufall, Weizhong Zhu, Kin Fai Au, Jiang Hong, Mark E. Anderson, Chad E. Grueter, Long-Sheng Song

Science. Author manuscript; available in PMC 2019 Dec 21.

Published in final edited form as: Science. 2018 Dec 21; 362(6421): eaan3303. Published online 2018 Nov 8. doi: 10.1126/science.aan3303

PMCID:: PMC6336677

Abstract Article PDF–2.4M

Select item 608429511.

Functional interaction of Junctophilin 2 with small‐ conductance Ca²⁺‐activated potassium channel subtype 2(SK2) in mouse cardiac myocytes

H. K. Fan, T. X. Luo, W. D. Zhao, Y. H. Mu, Y. Yang, W. J. Guo, H. Y. Tu, Q. Zhang

Acta Physiol (Oxf) 2018 Mar; 222(3): e12986. Published online 2017 Dec 7. doi: 10.1111/apha.12986

PMCID:: PMC6084295

Abstract Article PDF–2.2M

Select item 592488812.

Physical interaction of junctophilin and the Ca_V1.1 C terminus is crucial for skeletal muscle contraction

Tsutomu Nakada, Toshihide Kashihara, Masatoshi Komatsu, Katsuhiko Kojima, Toshikazu Takeshita, Mitsuhiko Yamada

Proc Natl Acad Sci U S A. 2018 Apr 24; 115(17): 4507–4512. Published online 2018 Apr 9. doi: 10.1073/pnas.1716649115

PMCID:: PMC5924888

Abstract Article PDF–2.1M

Select item 520101313.

Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes

Michelle L. Munro, Isuru D. Jayasinghe, Qiongling Wang, Ann Quick, Wei Wang, David Baddeley, Xander H. T. Wehrens, Christian Soeller

J Cell Sci. 2016 Dec 1; 129(23): 4388–4398. doi: 10.1242/jcs.196873

PMCID:: PMC5201013

Abstract Article

Select item 450504214.

Molecular Determinants of Calpain-dependent Cleavage of Junctophilin-2 Protein in Cardiomyocytes

Ang Guo, Duane Hall, Caimei Zhang, Tianqing Peng, Jordan D. Miller, William Kutschke, Chad E. Grueter, Frances L. Johnson, Richard Z. Lin, Long-Sheng Song

J Biol Chem. 2015 Jul 17; 290(29): 17946–17955. Published online 2015 Jun 10. doi: 10.1074/jbc.M115.652396

PMCID:: PMC4505042

Abstract Article PDF–2.3M

Select item 431856415.

Mutations in JPH2-Encoded Junctophilin-2 Associated with Hypertrophic Cardiomyopathy in Humans

Andrew P. Landstrom, Noah Weisleder, Karin B. Batalden, J. Martijn Bos, David J. Tester, Steve R. Ommen, Xander H.T Wehrens, William C. Claycomb, Jae-Kyun Ko, Moonsun Hwang, Zui Pan, Jianjie Ma, Michael J. Ackerman

J Mol Cell Cardiol. Author manuscript; available in PMC 2015 Feb 5.

Published in final edited form as: J Mol Cell Cardiol. 2007 Jun; 42(6): 1026–1035. Published online 2007 Apr 18. doi: 10.1016/j.yjmcc.2007.04.006

PMCID:: PMC4318564

Article PDF–899K

Select item 421700716.

Reduced junctional Na⁺/Ca²⁺-exchanger activity contributes to sarcoplasmic reticulum Ca²⁺ leak in junctophilin-2-deficient mice

Wei Wang, Andrew P. Landstrom, Qiongling Wang, Michelle L. Munro, David Beavers, Michael J. Ackerman, Christian Soeller, Xander H. T. Wehrens

Am J Physiol Heart Circ Physiol. 2014 Nov 1; 307(9): H1317–H1326. Published online 2014 Sep 5. doi: 10.1152/ajpheart.00413.2014

Correction in:: Am J Physiol Heart Circ Physiol. 2018 May 1; 314(5): H1115.

PMCID:: PMC4217007

Abstract Article

Select item 414302617.

Overexpression of junctophilin-2 does not enhance baseline function but attenuates heart failure development after cardiac stress

Ang Guo, Xiaoying Zhang, Venkat Ramesh Iyer, Biyi Chen, Caimei Zhang, William J. Kutschke, Robert M. Weiss, Clara Franzini-Armstrong, Long-Sheng Song

Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33): 12240–12245. Published online 2014 Aug 4. doi: 10.1073/pnas.1412729111

PMCID:: PMC4143026

Abstract Article PDF–1.5M

Select item 400630518.

Microtubule-Mediated Defects in Junctophilin-2 Trafficking Contribute to Myocyte T-Tubule Remodeling and Ca²⁺ Handling Dysfunction in Heart Failure

Caimei Zhang, Biyi Chen, Ang Guo, Yanqi Zhu, Jordan D. Miller, Shan Gao, Can Yuan, William Kutschke, Kathy Zimmerman, Robert M. Weiss, Xander H.T. Wehrens, Jiang Hong, Frances L. Johnson, Luis F. Santana, Mark E. Anderson, Long-Sheng Song

Circulation. Author manuscript; available in PMC 2015 Apr 29.

Published in final edited form as: Circulation. 2014 Apr 29; 129(17): 1742–1750. Published online 2014 Feb 11. doi: 10.1161/CIRCULATIONAHA.113.008452

PMCID:: PMC4006305

Abstract Article PDF–3.3M

Select item 383068819.

Mutation E169K in junctophilin-2 causes atrial fibrillation due to impaired RyR2 stabilization

David L. Beavers, Wei Wang, Sameer Ather, Niels Voigt, Alejandro Garbino, Sayali S. Dixit, Andrew P. Landstrom, Na Li, Qiongling Wang, Iacopo Olivotto, Dobromir Dobrev, Michael J. Ackerman, Xander H.T. Wehrens

J Am Coll Cardiol. Author manuscript; available in PMC 2014 Nov 19.

Published in final edited form as: J Am Coll Cardiol. 2013 Nov 19; 62(21): 10.1016/j.jacc.2013.06.052. Published online 2013 Aug 21. doi: 10.1016/j.jacc.2013.06.052

PMCID:: PMC3830688

Abstract Article PDF–2.6M

Select item 377896120.

Critical roles of junctophilin-2 in T-tubule and excitation–contraction coupling maturation during postnatal development

Biyi Chen, Ang Guo, Caimei Zhang, Rong Chen, Yanqi Zhu, Jiang Hong, William Kutschke, Kathy Zimmerman, Robert M. Weiss, Leonid Zingman, Mark E. Anderson, Xander H.T. Wehrens, Long-Sheng Song

Cardiovasc Res. 2013 Oct 1; 100(1): 54–62. Published online 2013 Jul 16. doi: 10.1093/cvr/cvt180

PMCID:: PMC3778961

Abstract Article PDF–1.5M

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