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Select item 111905731.

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development

Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga

Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722

PMCID:: PMC11190573

Abstract Article

Select item 107034192.

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Ahlam Alqahtani, Tamilvendhan Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathan Coxhead, Veronika Boczonadi, Alex Laude, Simon J. Cockell, Maureen A. Kane, Steven Lisgo, Deborah J. Henderson

PLoS Genet. 2023 Nov; 19(11): e1010777. Published online 2023 Nov 27. doi: 10.1371/journal.pgen.1010777

PMCID:: PMC10703419

Abstract Article PDF–9.6M

Select item 106564273.

GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter

Jennifer Kurz, Anna-Carina Weiss, Timo H.-W. Lüdtke, Lena Deuper, Mark-Oliver Trowe, Hauke Thiesler, Herbert Hildebrandt, Joerg Heineke, Stephen A. Duncan, Andreas Kispert

Development. 2022 Aug 1; 149(15): dev200522. Published online 2022 Jul 29. doi: 10.1242/dev.200522

PMCID:: PMC10656427

Abstract Article

Select item 104184494.

Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease

Marta Melis, Steven E. Trasino, Xiao-Han Tang, Andrew Rappa, Tuo Zhang, Lihui Qin, Lorraine J. Gudas

Int J Mol Sci. 2023 Aug; 24(15): 12035. Published online 2023 Jul 27. doi: 10.3390/ijms241512035

PMCID:: PMC10418449

Abstract Article PDF–5.8M

Select item 97118595.

Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs

Aysis Koshy, Elodie Mathieux, François Stüder, Aude Bramoulle, Michele Lieb, Bruno Maria Colombo, Hinrich Gronemeyer, Marco Antonio Mendoza-Parra

Life Sci Alliance. 2023 Feb; 6(2): e202201627. Published online 2022 Nov 29. doi: 10.26508/lsa.202201627

PMCID:: PMC9711859

Abstract Article PDF–4.7M

Select item 96658856.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 90930437.

Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity

Katharina Schönberger, Nadine Obier, Mari Carmen Romero-Mulero, Pierre Cauchy, Julian Mess, Polina V. Pavlovich, Yu Wei Zhang, Michael Mitterer, Jasmin Rettkowski, Maria-Eleni Lalioti, Karin Jäcklein, Jonathan D. Curtis, Betty Féret, Pia Sommerkamp, Claudia Morganti, Keisuke Ito, Norbert B. Ghyselinck, Eirini Trompouki, Joerg M. Buescher, Erika L. Pearce, Nina Cabezas-Wallscheid

Cell Stem Cell. Author manuscript; available in PMC 2022 May 11.

Published in final edited form as: Cell Stem Cell. 2022 Jan 6; 29(1): 131–148.e10. Published online 2021 Oct 26. doi: 10.1016/j.stem.2021.10.002

PMCID:: PMC9093043

Abstract Article PDF–3.5M

Select item 90181198.

Regulation of Prefrontal Patterning and Connectivity by Retinoic Acid

Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa, Nenad Sestan

Nature. Author manuscript; available in PMC 2022 Apr 19.

Published in final edited form as: Nature. 2021 Oct; 598(7881): 483–488. Published online 2021 Oct 1. doi: 10.1038/s41586-021-03953-x

PMCID:: PMC9018119

Abstract Article PDF–12M

Select item 89188089.

Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum

Zihao Su, Ziwu Wang, Susan Lindtner, Lin Yang, Zicong Shang, Yu Tian, Rongliang Guo, Yan You, Wenhao Zhou, John L. Rubenstein, Zhengang Yang, Zhuangzhi Zhang

Development. 2022 Feb 15; 149(4): dev200035. Published online 2022 Feb 23. doi: 10.1242/dev.200035

PMCID:: PMC8918808

Abstract Article

Select item 849232610.

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization

Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma

JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254

PMCID:: PMC8492326

Abstract Article PDF–3.4M

Select item 820361111.

A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects

Hélène Choquet, Ronald B. Melles, Deepti Anand, Jie Yin, Gabriel Cuellar-Partida, Wei Wang, 23andMe Research Team, Thomas J. Hoffmann, K. Saidas Nair, Pirro G. Hysi, Salil A. Lachke, Eric Jorgenson

Nat Commun. 2021; 12: 3595. Published online 2021 Jun 14. doi: 10.1038/s41467-021-23873-8

PMCID:: PMC8203611

Abstract Article PDF–1.9M

Select item 770785112.

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

Glenda Evangelina Comai, Markéta Tesařová, Valérie Dupé, Muriel Rhinn, Pedro Vallecillo-García, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, François Spitz, Sigmar Stricker, Tomáš Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B. Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh

PLoS Biol. 2020 Nov; 18(11): e3000902. Published online 2020 Nov 17. doi: 10.1371/journal.pbio.3000902

PMCID:: PMC7707851

Abstract Article PDF–5.0M

Select item 730523513.

Nolz1 expression is required in dopaminergic axon guidance and striatal innervation

Clement Soleilhavoup, Marco Travaglio, Kieran Patrick, Pedro Garção, Elangovan Boobalan, Youri Adolfs, Ruth V. Spriggs, Emma Moles-Garcia, Dalbir Dhiraj, Tony Oosterveen, Sarah L. Ferri, Ted Abel, Edward S. Brodkin, R. Jeroen Pasterkamp, Brian P. Brooks, Lia Panman

Nat Commun. 2020; 11: 3111. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16947-6

PMCID:: PMC7305235

Abstract Article PDF–9.5M

Select item 725979414.

Discovery of genes required for body axis and limb formation by global identification of retinoic acid–regulated epigenetic marks

Marie Berenguer, Karolin F. Meyer, Jun Yin, Gregg Duester

PLoS Biol. 2020 May; 18(5): e3000719. Published online 2020 May 18. doi: 10.1371/journal.pbio.3000719

PMCID:: PMC7259794

Abstract Article PDF–3.2M

Select item 724431715.

Retinoic acid synthesis by ALDH1A proteins is dispensable for meiosis initiation in the mouse fetal ovary

Anne-Amandine Chassot, Morgane Le Rolle, Geneviève Jolivet, Isabelle Stevant, Jean-Marie Guigonis, Fabio Da Silva, Serge Nef, Eric Pailhoux, Andreas Schedl, Norbert B. Ghyselinck, Marie-Christine Chaboissier

Sci Adv. 2020 May; 6(21): eaaz1261. Published online 2020 May 22. doi: 10.1126/sciadv.aaz1261

PMCID:: PMC7244317

Abstract Article PDF–5.0M

Select item 720618516.

Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis

Masataka Someda, Shunsuke Kuroki, Hitoshi Miyachi, Makoto Tachibana, Shin Yonehara

Cell Death Differ. 2020 May; 27(5): 1539–1553. Published online 2019 Oct 28. doi: 10.1038/s41418-019-0434-2

PMCID:: PMC7206185

Abstract Article PDF–5.4M

Select item 715667117.

Transgene integration causes RARB downregulation in homozygous Tg4–42 mice

Barbara Hinteregger, Tina Loeffler, Stefanie Flunkert, Joerg Neddens, Ruth Birner-Gruenberger, Thomas A. Bayer, Tobias Madl, Birgit Hutter-Paier

Sci Rep. 2020; 10: 6377. Published online 2020 Apr 14. doi: 10.1038/s41598-020-63512-8

PMCID:: PMC7156671

Abstract Article PDF–1.7M

Select item 704445318.

Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development

Edward Daniel, Haley R. Barlow, Gabrielle I. Sutton, Xiaowu Gu, Yadanar Htike, Mitzy A. Cowdin, Ondine Cleaver

Development. 2020 Feb 15; 147(4): dev181560. Published online 2020 Feb 20. doi: 10.1242/dev.181560

PMCID:: PMC7044453

Abstract Article

Select item 702815019.

BMPs are direct triggers of interdigital programmed cell death

Maria M. Kaltcheva, Matthew J. Anderson, Brian D. Harfe, Mark Lewandoski

Dev Biol. Author manuscript; available in PMC 2020 Feb 18.

Published in final edited form as: Dev Biol. 2016 Mar 15; 411(2): 266–276. Published online 2016 Jan 27. doi: 10.1016/j.ydbio.2015.12.016

PMCID:: PMC7028150

Abstract Article PDF–2.3M

Select item 689540220.

Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ)

Heng-Jia Liu, Hilaire C. Lam, Christian V. Baglini, Julie Nijmeh, Alischer A. Cottrill, Stephen Y. Chan, Elizabeth P. Henske

Oncogene. Author manuscript; available in PMC 2019 Dec 6.

Published in final edited form as: Oncogene. 2019 Dec; 38(49): 7367–7383. Published online 2019 Aug 16. doi: 10.1038/s41388-019-0957-5

PMCID:: PMC6895402

Abstract Article PDF–2.0M

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