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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Oxygen availability influences the incidence of testicular teratoma in Dnd1Ter/+ mice
Ximena M. Bustamante-Marin, Blanche Capel
Front Genet. 2023; 14: 1179256. Published online 2023 Apr 26. doi: 10.3389/fgene.2023.1179256
PMCID:
PMC10169730
AbstractArticlePDF–2.6M
3.
The Mc4r gene is responsible for the development of experimentally induced testicular teratomas
Syunsuke Seki, Kaoru Ohura, Takehiro Miyazaki, Abdullah An Naser, Shuji Takabayashi, Eisei Tsutsumi, Toshinobu Tokumoto
Sci Rep. 2023; 13: 6756. Published online 2023 May 1. doi: 10.1038/s41598-023-32784-1
PMCID:
PMC10151343
AbstractArticlePDF–2.2M
4.
Loss of Dead end1 induces testicular teratomas from primordial germ cells that failed to undergo sexual differentiation in embryonic testes
Atsuki Imai, Kazuya Matsuda, Yuki Niimi, Atsushi Suzuki
Sci Rep. 2023; 13: 6398. Published online 2023 Apr 19. doi: 10.1038/s41598-023-33706-x
PMCID:
PMC10115811
AbstractArticlePDF–4.3M
5.
Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions
Xiaowei Gu, Anna Heinrich, Shu-Yun Li, Tony DeFalco
Nat Commun. 2023; 14: 1439. Published online 2023 Mar 15. doi: 10.1038/s41467-023-37199-0
PMCID:
PMC10017703
AbstractArticlePDF–16M
6.
The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation
Victor A. Ruthig, Talia Hatkevich, Josiah Hardy, Matthew B. Friedersdorf, Chloé Mayère, Serge Nef, Jack D. Keene, Blanche Capel
PLoS Genet. 2023 Mar; 19(3): e1010656. Published online 2023 Mar 1. doi: 10.1371/journal.pgen.1010656
PMCID:
PMC10010562
AbstractArticlePDF–2.8M
7.
Cdc42 activity in Sertoli cells is essential for maintenance of spermatogenesis
Anna Heinrich, Bidur Bhandary, Sarah J. Potter, Nancy Ratner, Tony DeFalco
Cell Rep. Author manuscript; available in PMC 2021 Nov 19.
Published in final edited form as: Cell Rep. 2021 Oct 26; 37(4): 109885. doi: 10.1016/j.celrep.2021.109885
PMCID:
PMC8604081
AbstractArticlePDF–2.2M
8.
A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells
Victor A Ruthig, Tetsuhiro Yokonishi, Matthew B Friedersdorf, Sofia Batchvarova, Josiah Hardy, Jason A Garness, Jack D Keene, Blanche Capel
Biol Reprod. 2021 Apr; 104(4): 861–874. Published online 2021 Jan 4. doi: 10.1093/biolre/ioaa233
PMCID:
PMC8324984
AbstractArticlePDF–1.6M
9.
MC4R mutant mice develop ovarian teratomas
Abdullah An Naser, Takehiro Miyazaki, Jun Wang, Shuji Takabayashi, Theeranukul Pachoensuk, Toshinobu Tokumoto
Sci Rep. 2021; 11: 3483. Published online 2021 Feb 10. doi: 10.1038/s41598-021-83001-w
PMCID:
PMC7876032
AbstractArticlePDF–4.8M
10.
Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis
Anna Heinrich, Sarah J. Potter, Li Guo, Nancy Ratner, Tony DeFalco
Cell Rep. Author manuscript; available in PMC 2020 May 11.
Published in final edited form as: Cell Rep. 2020 Apr 14; 31(2): 107513. doi: 10.1016/j.celrep.2020.03.077
PMCID:
PMC7213061
AbstractArticlePDF–4.4M
11.
Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence
Atsuki Imai, Yoshihiko Hagiwara, Yuki Niimi, Toshinobu Tokumoto, Yumiko Saga, Atsushi Suzuki
PLoS One. 2020; 15(4): e0232047. Published online 2020 Apr 27. doi: 10.1371/journal.pone.0232047
PMCID:
PMC7185693
AbstractArticlePDF–3.0M
12.
The RNA-binding protein DND1 acts sequentially as a negative regulator of pluripotency and a positive regulator of epigenetic modifiers required for germ cell reprogramming
Victor A. Ruthig, Matthew B. Friedersdorf, Jason A. Garness, Steve C. Munger, Corey Bunce, Jack D. Keene, Blanche Capel
Development. 2019 Oct 1; 146(19): dev175950. Published online 2019 Jul 25. doi: 10.1242/dev.175950
PMCID:
PMC6803376
AbstractArticle
13.
Left-Biased Spermatogenic Failure in 129/SvJ Dnd1Ter/+ Mice Correlates with Differences in Vascular Architecture, Oxygen Availability, and Metabolites
Ximena M. Bustamante-Marin, Matthew S. Cook, Jessica Gooding, Christopher Newgard, Blanche Capel
Biol Reprod. 2015 Sep; 93(3): 78, 1-13. doi: 10.1095/biolreprod.115.128850
PMCID:
PMC6322448
AbstractArticlePDF–2.6M
14.
Dnd1-mediated epigenetic control of teratoma formation in mouse
Wei Gu, Kentaro Mochizuki, Kei Otsuka, Ryohei Hamada, Asuka Takehara, Yasuhisa Matsui
Biol Open. 2018 Jan 15; 7(1): bio032318. Published online 2018 Jan 15. doi: 10.1242/bio.032318
PMCID:
PMC5829515
AbstractArticlePDF–2.1M
15.
Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer
Timothy M. Pierpont, Amy M. Lyndaker, Claire M. Anderson, Qiming Jin, Elizabeth S. Moore, Jamie L. Roden, Alicia Braxton, Lina Bagepalli, Nandita Kataria, Hilary Zhaoxu Hu, Jason Garness, Matthew S. Cook, Blanche Capel, Donald H. Schlafer, Teresa Southard, Robert S. Weiss
Cell Rep. Author manuscript; available in PMC 2017 Nov 20.
Published in final edited form as: Cell Rep. 2017 Nov 14; 21(7): 1896–1909. doi: 10.1016/j.celrep.2017.10.078
PMCID:
PMC5695237
AbstractArticlePDF–1.6M
16.
Do Gametes Woo? Evidence for Their Nonrandom Union at Fertilization
Joseph H. Nadeau
Genetics. 2017 Oct; 207(2): 369–387. Published online 2017 Sep 29. doi: 10.1534/genetics.117.300109
PMCID:
PMC5629312
AbstractArticlePDF–957K
17.
DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs
Masashi Yamaji, Miki Jishage, Cindy Meyer, Hemant Suryawanshi, Evan Der, Misaki Yamaji, Aitor Garzia, Pavel Morozov, Sudhir Manickavel, Hannah L. McFarland, Robert G. Roeder, Markus Hafner, Thomas Tuschl
Nature. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: Nature. 2017 Mar 23; 543(7646): 568–572. Published online 2017 Mar 15. doi: 10.1038/nature21690
PMCID:
PMC5488729
AbstractArticlePDF–2.4M
18.
Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development
Atsushi Suzuki, Yuki Niimi, Kaori Shinmyozu, Zhi Zhou, Makoto Kiso, Yumiko Saga
EMBO Rep. 2016 Jan; 17(1): 37–46. Published online 2015 Nov 20. doi: 10.15252/embr.201540828
PMCID:
PMC4718414
AbstractArticlePDF–2.0M
19.
APOBEC3 inhibits DEAD-END function to regulate microRNA activity
Sara Ali, Namrata Karki, Chitralekha Bhattacharya, Rui Zhu, Donna A MacDuff, Mark D Stenglein, April J Schumacher, Zachary L Demorest, Reuben S Harris, Angabin Matin, Sita Aggarwal
BMC Mol Biol. 2013; 14: 16. Published online 2013 Jul 26. doi: 10.1186/1471-2199-14-16
PMCID:
PMC3729616
AbstractArticlePDF–1.1M
20.
Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis
Jennifer L Zechel, Stephanie K Doerner, Angela Lager, Paul J Tesar, Jason D Heaney, Joseph H Nadeau
BMC Genet. 2013; 14: 54. Published online 2013 Jun 17. doi: 10.1186/1471-2156-14-54
PMCID:
PMC3693958
AbstractArticlePDF–666K

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