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Select item 104532271.

Sirtuin 6 Overexpression Improves Rotator Cuff Tendon-to-Bone Healing in the Aged

Young Jae Moon, Baoning Cui, Se-Young Cho, Jae Won Hwang, Hee-Chung Chung, Joseph Kwon, Duwoon Kim, Kyu Yun Jang, Jung Ryul Kim, Sung Il Wang

Cells. 2023 Aug; 12(16): 2035. Published online 2023 Aug 10. doi: 10.3390/cells12162035

PMCID:: PMC10453227

Abstract Article PDF–1.9M

Select item 102580032.

DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

Yang Hou, Jiangang Shi, Yongfei Guo, Guodong Shi

Aging (Albany NY) 2023 May 31; 15(10): 4288–4303. Published online 2023 May 17. doi: 10.18632/aging.204729

PMCID:: PMC10258003

Abstract Article PDF–1.5M

Select item 97922023.

Downregulation of Sirt6 by CD38 promotes cell senescence and aging

Hongji Zhou, Shihai Liu, NanYang Zhang, Kehua Fang, Jinbao Zong, Yi An, Xiaotian Chang

Aging (Albany NY) 2022 Dec 15; 14(23): 9730–9757. Published online 2022 Dec 6. doi: 10.18632/aging.204425

PMCID:: PMC9792202

Abstract Article PDF–3.0M

Select item 95847364.

SIRT6 Prevents Glucocorticoid-Induced Osteonecrosis of the Femoral Head in Rats

Lun Fang, Gang Zhang, Yadi Wu, Zhongzhe Li, Shan Gao, Lu Zhou

Oxid Med Cell Longev. 2022; 2022: 6360133. Published online 2022 Oct 13. doi: 10.1155/2022/6360133

PMCID:: PMC9584736

Abstract Article PDF–3.1M

Select item 90957115.

Energy restriction induced SIRT6 inhibits microglia activation and promotes angiogenesis in cerebral ischemia via transcriptional inhibition of TXNIP

Ming-Yu Song, Fang Yi, Hui Xiao, Jun Yin, Qing Huang, Jian Xia, Xiao-Meng Yin, Yan-Bin Wen, Le Zhang, Yun-Hai Liu, Bo Xiao, Wen-Ping Gu

Cell Death Dis. 2022 May; 13(5): 449. Published online 2022 May 11. doi: 10.1038/s41419-022-04866-x

PMCID:: PMC9095711

Abstract Article PDF–6.0M

Select item 73985386.

Influence of the maternal high-intensity-interval-training on the cardiac Sirt6 and lipid profile of the adult male offspring in rats

Reihaneh Mohammadkhani, Neda Khaledi, Hamid Rajabi, Iraj Salehi, Alireza Komaki

PLoS One. 2020; 15(8): e0237148. Published online 2020 Aug 3. doi: 10.1371/journal.pone.0237148

PMCID:: PMC7398538

Abstract Article PDF–1.7M

Select item 65616227.

Overexpression of Sirt6 promotes M2 macrophage transformation, alleviating renal injury in diabetic nephropathy

Liqiang Ji, Yifang Chen, Hongqiang Wang, Wei Zhang, Lanxiang He, Jingmin Wu, Yinghui Liu

Int J Oncol. 2019 Jul; 55(1): 103–115. Published online 2019 May 14. doi: 10.3892/ijo.2019.4800

PMCID:: PMC6561622

Abstract Article PDF–1.6M

Select item 63171138.

Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals

Marcos C. Carreira, Andrea G. Izquierdo, Maria Amil, Felipe F. Casanueva, Ana B. Crujeiras

Oxid Med Cell Longev. 2018; 2018: 6256052. Published online 2018 Dec 23. doi: 10.1155/2018/6256052

PMCID:: PMC6317113

Abstract Article PDF–1.0M

Select item 49605489.

Insulin secretion impairment in Sirt6 knockout pancreatic β cells is mediated by suppression of the FoxO1-Pdx1-Glut2 pathway

Mi-Young Song, Jie Wang, Sun-O Ka, Eun Ju Bae, Byung-Hyun Park

Sci Rep. 2016; 6: 30321. Published online 2016 Jul 26. doi: 10.1038/srep30321

PMCID:: PMC4960548

Abstract Article PDF–1.2M

Select item 470217510.

Overexpression of SIRT6 in the hippocampal CA1 impairs the formation of long-term contextual fear memory

Xi Yin, Yuan Gao, Hai-Shui Shi, Li Song, Jie-Chao Wang, Juan Shao, Xu-Hong Geng, Gai Xue, Jian-Li Li, Yan-Ning Hou

Sci Rep. 2016; 6: 18982. Published online 2016 Jan 6. doi: 10.1038/srep18982

PMCID:: PMC4702175

Abstract Article PDF–1.1M

Select item 381464211.

Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors

Narendra Wajapeyee, Sunil K. Malonia, Rajendra K. Palakurthy, Michael R. Green

Genes Dev. 2013 Oct 15; 27(20): 2221–2226. doi: 10.1101/gad.227413.113

PMCID:: PMC3814642

Abstract Article PDF–1.0M

Select item 357000812.

Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity

Shan-Shan Yu, Yi Cai, Jian-Tao Ye, Rong-Biao Pi, Shao-Rui Chen, Pei-Qing Liu, Xiao-Yan Shen, Yong Ji

Br J Pharmacol. 2013 Jan; 168(1): 117–128. doi: 10.1111/j.1476-5381.2012.01903.x

PMCID:: PMC3570008

Abstract Article PDF–1.7M

Select item 356778613.

SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence

Anna Cardus, Anna K. Uryga, Gareth Walters, Jorge D. Erusalimsky

Cardiovasc Res. 2013 Mar 1; 97(3): 571–579. Published online 2012 Dec 1. doi: 10.1093/cvr/cvs352

PMCID:: PMC3567786

Abstract Article PDF–440K

Select item 352810114.

SIRT6 is required for maintenance of telomere position effect in human cells

Ruth I. Tennen, Dennis J. Bua, Woodring E. Wright, Katrin F. Chua

Nat Commun. Author manuscript; available in PMC 2012 Dec 21.

Published in final edited form as: Nat Commun. 2011; 2: 433. Published online 2011 Aug 16. doi: 10.1038/ncomms1443

PMCID:: PMC3528101

Abstract Article PDF–1.0M

Select item 352695315.

THE HISTONE DEACETYLASE SIRT6 IS A NOVEL TUMOR SUPPRESSOR THAT CONTROLS CANCER METABOLISM

Carlos Sebastián, Bernardette M. M. Zwaans, Dafne M. Silberman, Melissa Gymrek, Alon Goren, Lei Zhong, Oren Ram, Jessica Truelove, Alexander R. Guimaraes, Debra Toiber, Claudia Cosentino, Joel K. Greenson, Alasdair I Mac Donald, Liane McGlynn, Fraser Maxwell, Joanne Edwards, Sofia Giacosa, Ernesto Guccione, Ralph Weissleder, Bradley E. Bernstein, Aviv Regev, Paul G. Shiels, David B. Lombard, Raul Mostoslavsky

Cell. Author manuscript; available in PMC 2013 Dec 7.

Published in final edited form as: Cell. 2012 Dec 7; 151(6): 1185–1199. doi: 10.1016/j.cell.2012.10.047

PMCID:: PMC3526953

Abstract Article PDF–2.3M

Select item 326369716.

Regulation of SIRT6 protein levels by nutrient availability

Yariv Kanfi, Ronnie Shalman, Victoria Peshti, Shmuel N. Pilosof, Yosi M. Gozlan, Kevin J. Pearson, Batya Lerrer, Danesh Moazed, Jean-Christophe Marine, Rafael de Cabo, Haim Y. Cohen

FEBS Lett. Author manuscript; available in PMC 2012 Jan 23.

Published in final edited form as: FEBS Lett. 2008 Mar 5; 582(5): 543–548. Published online 2008 Jan 31. doi: 10.1016/j.febslet.2008.01.019

PMCID:: PMC3263697

Abstract Article PDF–1.0M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304415518.

Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats

Soo Jin Yang, Jung Mook Choi, Seoung Wan Chae, Won Jun Kim, Se Eun Park, Eun Jung Rhee, Won Young Lee, Ki Won Oh, Sung Woo Park, Sun Woo Kim, Cheol-Young Park

PLoS One. 2011; 6(2): e17057. Published online 2011 Feb 23. doi: 10.1371/journal.pone.0017057

PMCID:: PMC3044155

Abstract Article PDF–2.1M

Select item 299751619.

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

Alessia Peserico, Cristiano Simone

J Biomed Biotechnol. 2011; 2011: 371832. Published online 2010 Dec 5. doi: 10.1155/2011/371832

PMCID:: PMC2997516

Abstract Article PDF–827K

Select item 287299120.

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

Erika Koltai, Zsofia Szabo, Mustafa Atalay, Istvan Boldogh, Hisashi Naito, Sataro Goto, Csaba Nyakas, Zsolt Radak

Mech Ageing Dev. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Mech Ageing Dev. 2010 Jan; 131(1): 21–28. Published online 2009 Nov 12. doi: 10.1016/j.mad.2009.11.002

PMCID:: PMC2872991

Abstract Article PDF–1.3M

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