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Select item 111928241.

Pan-cancer exploration of oncogenic and clinical impacts revealed that HOXA9 is a diagnostic indicator of tumorigenesis

U. Sangeetha Shenoy, Dhanraj Salur Basavarajappa, Shama Prasada Kabekkodu, Raghu Radhakrishnan

Clin Exp Med. 2024; 24(1): 134. Published online 2024 Jun 21. doi: 10.1007/s10238-024-01389-x

PMCID:: PMC11192824

Abstract Article PDF–8.5M

Select item 107855522.

RNA-binding protein RBM5 plays an essential role in acute myeloid leukemia by activating the oncogenic protein HOXA9

Mengli Zhang, Judith Hyle, Xiaowen Chen, Ye Xin, Yingcai Jin, Jianxiang Zhang, Xue Yang, Xinfeng Chen, Shaela Wright, Zhenling Liu, Wojciech Rosikiewicz, Beisi Xu, Liusheng He, Hong Liu, Nana Ping, Depei Wu, Feiqiu Wen, Chunliang Li, Peng Xu

Genome Biol. 2024; 25: 16. Published online 2024 Jan 12. doi: 10.1186/s13059-023-03149-8

PMCID:: PMC10785552

Abstract Article PDF–9.6M

Select item 101131763.

HOXA9 forms a repressive complex with nuclear matrix–associated protein SAFB to maintain acute myeloid leukemia

Shuchi Agrawal-Singh, Jaana Bagri, George Giotopoulos, Dhoyazan M. A. Azazi, Sarah J. Horton, Cecile K. Lopez, Shubha Anand, Anne-Sophie Bach, Frances Stedham, Robin Antrobus, Jack W. Houghton, George S. Vassiliou, Daniel Sasca, Haiyang Yun, Anthony D. Whetton, Brian J. P. Huntly

Blood. 2023 Apr 6; 141(14): 1737–1754. Published online 2022 Dec 30. doi: 10.1182/blood.2022016528

PMCID:: PMC10113176

Abstract Article

Select item 95301174.

HOXA9 has the hallmarks of a biological switch with implications in blood cancers

Laure Talarmain, Matthew A. Clarke, David Shorthouse, Lilia Cabrera-Cosme, David G. Kent, Jasmin Fisher, Benjamin A. Hall

Nat Commun. 2022; 13: 5829. Published online 2022 Oct 3. doi: 10.1038/s41467-022-33189-w

PMCID:: PMC9530117

Abstract Article PDF–5.4M

Select item 94408015.

circ_0052184 Promotes Colorectal Cancer Progression via Targeting miR-604/HOXA9 Axis

Yandong Huang, Qinyang Bai, Zhanlong Wang, Hongbo Yu, Yanru Li, Hao Lu, Huimin Kang, Xuewei Shi, Kai Feng

Anal Cell Pathol (Amst) 2022; 2022: 8583382. Published online 2022 Aug 27. doi: 10.1155/2022/8583382

PMCID:: PMC9440801

Abstract Article PDF–1.6M

Select item 92241606.

HOXA9 Overexpression Contributes to Stem Cell Overpopulation That Drives Development and Growth of Colorectal Cancer

Brian Osmond, Caroline O. B. Facey, Chi Zhang, Bruce M. Boman

Int J Mol Sci. 2022 Jun; 23(12): 6799. Published online 2022 Jun 18. doi: 10.3390/ijms23126799

PMCID:: PMC9224160

Abstract Article PDF–3.1M

Select item 89709527.

Comprehensive Landscape of HOXA2, HOXA9, and HOXA10 as Potential Biomarkers for Predicting Progression and Prognosis in Prostate Cancer

Yan-ping Song, Peng Xian, Hong Luo, Jun-yong Dai, Yu Bai, Yuan Li, Xian-li Tang

J Immunol Res. 2022; 2022: 5740971. Published online 2022 Mar 24. doi: 10.1155/2022/5740971

PMCID:: PMC8970952

Abstract Article PDF–5.5M

Select item 87436478.

ALKBH5‐mediated m6A modification of lncRNA KCNQ1OT1 triggers the development of LSCC via upregulation of HOXA9

Yushan Li, Bingrui Yan, Xin Wang, Qiuying Li, Xuan Kan, Jingting Wang, Yanan Sun, Peng Wang, Linli Tian, Ming Liu

J Cell Mol Med. 2022 Jan; 26(2): 385–398. Published online 2021 Dec 1. doi: 10.1111/jcmm.17091

PMCID:: PMC8743647

Abstract Article PDF–1.9M

Select item 86474099.

Phase separation drives aberrant chromatin looping and cancer development

Jeong Hyun Ahn, Eric S. Davis, Timothy A. Daugird, Shuai Zhao, Ivana Yoseli Quiroga, Hidetaka Uryu, Jie Li, Aaron J. Storey, Yi-Hsuan Tsai, Daniel P. Keeley, Samuel G. Mackintosh, Ricky D. Edmondson, Stephanie D. Byrum, Ling Cai, Alan J. Tackett, Deyou Zheng, Wesley R. Legant, Douglas H Phanstiel, Gang Greg Wang

Nature. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Nature. 2021 Jul; 595(7868): 591–595. Published online 2021 Jun 23. doi: 10.1038/s41586-021-03662-5

PMCID:: PMC8647409

Abstract Article PDF–7.4M

Select item 861614610.

The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype

Marcela Vaz, Birthe Fahrenkrog

Cells. 2021 Nov; 10(11): 2851. Published online 2021 Oct 22. doi: 10.3390/cells10112851

PMCID:: PMC8616146

Abstract Article PDF–4.5M

Select item 837983811.

MicroRNA-638 inhibits the progression of breast cancer through targeting HOXA9 and suppressing Wnt/β-cadherin pathway

Qian Xu, Qianqian Zhang, Mengli Dong, Yuan Yu

World J Surg Oncol. 2021; 19: 247. Published online 2021 Aug 20. doi: 10.1186/s12957-021-02363-7

PMCID:: PMC8379838

Abstract Article PDF–3.1M

Select item 830719412.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812491714.

Nuclear FGFR2 Interacts with the MLL-AF4 Oncogenic Chimera and Positively Regulates HOXA9 Gene Expression in t(4;11) Leukemia Cells

Tiziana Fioretti, Armando Cevenini, Mariateresa Zanobio, Maddalena Raia, Daniela Sarnataro, Fabio Cattaneo, Rosario Ammendola, Gabriella Esposito

Int J Mol Sci. 2021 May; 22(9): 4623. Published online 2021 Apr 28. doi: 10.3390/ijms22094623

PMCID:: PMC8124917

Abstract Article PDF–14M

Select item 800904815.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 797643416.

Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9

Seiko Yoshino, Takashi Yokoyama, Yoshitaka Sunami, Tomoko Takahara, Aya Nakamura, Yukari Yamazaki, Shuichi Tsutsumi, Hiroyuki Aburatani, Takuro Nakamura

Blood. 2021 Jan 7; 137(1): 75–88. Prepublished online 2020 Jul 30. doi: 10.1182/blood.2019004586

PMCID:: PMC7976434

Abstract Article

Select item 796225217.

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex

Xin Wang, Wei Jiang, Shuo Luo, Xiaoyu Yang, Changnan Wang, Bingying Wang, Yongjun Dang, Yin Shen, Dengke K. Ma

Mol Brain. 2021; 14: 54. Published online 2021 Mar 16. doi: 10.1186/s13041-021-00767-w

PMCID:: PMC7962252

Abstract Article PDF–6.5M

Select item 785111218.

HOXA9/IRX1 expression pattern defines two subgroups of infant MLL-AF4-driven acute lymphoblastic leukemia

Vasiliki Symeonidou, Katrin Ottersbach

Exp Hematol. 2021 Jan; 93: 38–43.e5. doi: 10.1016/j.exphem.2020.10.002

PMCID:: PMC7851112

Abstract Article PDF–3.7M

Select item 776914519.

Gene- and species-specific Hox mRNA translation by ribosome expansion segments

Kathrin Leppek, Kotaro Fujii, Nick Quade, Teodorus Theo Susanto, Daniel Boehringer, Tea Lenarčič, Shifeng Xue, Naomi R. Genuth, Nenad Ban, Maria Barna

Mol Cell. Author manuscript; available in PMC 2021 Dec 17.

Published in final edited form as: Mol Cell. 2020 Dec 17; 80(6): 980–995.e13. Published online 2020 Nov 16. doi: 10.1016/j.molcel.2020.10.023

PMCID:: PMC7769145

Abstract Article PDF–3.1M

Select item 759906620.

Functional interrogation of HOXA9 regulome in MLLr leukemia via reporter-based CRISPR/Cas9 screen

Hao Zhang, Yang Zhang, Xinyue Zhou, Shaela Wright, Judith Hyle, Lianzhong Zhao, Jie An, Xujie Zhao, Ying Shao, Beisi Xu, Hyeong-Min Lee, Taosheng Chen, Yang Zhou, Xiang Chen, Rui Lu, Chunliang Li

eLife. 2020; 9: e57858. Published online 2020 Oct 1. doi: 10.7554/eLife.57858

PMCID:: PMC7599066

Abstract Article PDF–5.3M

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