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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Role of the Beta and Gamma Isoforms of the Adapter Protein SH2B1 in Regulating Energy Balance
Lawrence S Argetsinger, Anabel Flores, Nadezhda Svezhova, Michael Ellis, Caitlin Reynolds, Jessica L Cote, Joel M Cline, Martin G Myers, Jr, Christin Carter-Su
Endocrinology. 2023 May; 164(5): bqad032. Published online 2023 Feb 17. doi: 10.1210/endocr/bqad032
PMCID:
PMC10282918
AbstractArticle
3.
Neuronal SH2B1 attenuates apoptosis in an MPTP mouse model of Parkinson's disease via promoting PLIN4 degradation
Xiaojuan Han, Yuan Liu, Yan Dai, Tianshu Xu, Qinghui Hu, Xiaolan Yi, Liangyou Rui, Gang Hu, Jun Hu
Redox Biol. 2022 Jun; 52: 102308. Published online 2022 Apr 1. doi: 10.1016/j.redox.2022.102308
PMCID:
PMC8987406
AbstractArticlePDF–14M
4.
The nucleolar δ isoform of adapter protein SH2B1 enhances morphological complexity and function of cultured neurons
Jessica L. Cote, Paul B. Vander, Michael Ellis, Joel M. Cline, Nadezhda Svezhova, Michael E. Doche, Travis J. Maures, Tahrim A. Choudhury, Seongbae Kong, Olivia G. J. Klaft, Ray M. Joe, Lawrence S. Argetsinger, Christin Carter-Su
J Cell Sci. 2022 Feb 1; 135(3): jcs259179. Published online 2022 Feb 14. doi: 10.1242/jcs.259179
PMCID:
PMC8918807
AbstractArticle
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Deletion of the Brain-Specific α and δ Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity
Jessica L. Cote, Lawrence S. Argetsinger, Anabel Flores, Alan C. Rupp, Joel M. Cline, Lauren C. DeSantis, Alexander H. Bedard, Devika P. Bagchi, Paul B. Vander, Abrielle M. Cacciaglia, Erik S. Clutter, Gowri Chandrashekar, Ormond A. MacDougald, Martin G. Myers, Jr., Christin Carter-Su
Diabetes. 2021 Feb; 70(2): 400–414. Published online 2020 Nov 19. doi: 10.2337/db20-0687
PMCID:
PMC7881872
AbstractArticlePDF–2.6M
7.
Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease
Lin Jiang, Haoran Su, Xiaoyin Wu, Hong Shen, Min-Hyun Kim, Yuan Li, Martin G. Myers, Jr, Chung Owyang, Liangyou Rui
Nat Commun. 2020; 11: 1517. Published online 2020 Mar 23. doi: 10.1038/s41467-020-15328-3
Correction in:
Nat Commun. 2020; 11: 5310.
PMCID:
PMC7089966
AbstractArticlePDF–5.3M
8.
Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance
Anabel Flores, Lawrence S. Argetsinger, Lukas K.J. Stadler, Alvaro E. Malaga, Paul B. Vander, Lauren C. DeSantis, Ray M. Joe, Joel M. Cline, Julia M. Keogh, Elana Henning, Ines Barroso, Edson Mendes de Oliveira, Gowri Chandrashekar, Erik S. Clutter, Yixin Hu, Jeanne Stuckey, I. Sadaf Farooqi, Martin G. Myers, Jr., Christin Carter-Su
Diabetes. 2019 Nov; 68(11): 2049–2062. Published online 2019 Aug 22. doi: 10.2337/db19-0608
PMCID:
PMC6804625
AbstractArticlePDF–2.3M
9.
The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus
Johanna Giuranna, Anna-Lena Volckmar, Anna Heinen, Triinu Peters, Börge Schmidt, Anne Spieker, Helena Straub, Harald Grallert, Timo D. Müller, Jochen Antel, Ute Haußmann, Hans Klafki, Rui Liangyou, Johannes Hebebrand, Anke Hinney
Obes Facts. 2018 May; 11(2): 93–108. Published online 2018 Apr 10. doi: 10.1159/000486962
Correction in:
Obes Facts. 2018 Jul; 11(3): 176–180.
PMCID:
PMC5981666
AbstractArticlePDF–1.0M
10.
The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling
Filipa Franquinho, Joana Nogueira-Rodrigues, Joana M. Duarte, Sofia S. Esteves, Christin Carter-Su, Anthony P. Monaco, Zoltán Molnár, Antonio Velayos-Baeza, Pedro Brites, Mónica M. Sousa
Cereb Cortex. 2017 Mar; 27(3): 1732–1747. Published online 2017 Feb 17. doi: 10.1093/cercor/bhx023
PMCID:
PMC5905272
AbstractArticlePDF–1.7M
11.
Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression
Lin Jiang, Haoran Su, Julia M. Keogh, Zheng Chen, Elana Henning, Paul Wilkinson, Ian Goodyer, I. Sadaf Farooqi, Liangyou Rui
FASEB J. 2018 Apr; 32(4): 1830–1840. Published online 2018 Jan 5. doi: 10.1096/fj.201700831R
PMCID:
PMC5893167
AbstractArticle
12.
4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass
Manuel Blandino-Rosano, Joshua O. Scheys, Margarita Jimenez-Palomares, Rebecca Barbaresso, Aaron S. Bender, Akiko Yanagiya, Ming Liu, Liangyou Rui, Nahum Sonenberg, Ernesto Bernal-Mizrachi
Diabetes. 2016 Aug; 65(8): 2235–2248. Published online 2016 May 23. doi: 10.2337/db15-1443
PMCID:
PMC4955981
AbstractArticlePDF–2.3M
13.
SH2B1 in β-Cells Promotes Insulin Expression and Glucose Metabolism in Mice
Zheng Chen, David L. Morris, Lin Jiang, Yong Liu, Liangyou Rui
Mol Endocrinol. 2014 May; 28(5): 696–705. Published online 2014 Mar 19. doi: 10.1210/me.2013-1333
PMCID:
PMC4004774
AbstractArticle
14.
SH2B1 in β-Cells Regulates Glucose Metabolism by Promoting β-Cell Survival and Islet Expansion
Zheng Chen, David L. Morris, Lin Jiang, Yong Liu, Liangyou Rui
Diabetes. 2014 Feb; 63(2): 585–595. Published online 2014 Jan 16. doi: 10.2337/db13-0666
PMCID:
PMC3900537
AbstractArticlePDF–1.5M
15.
Hepatic SH2B1 and SH2B2 Regulate Liver Lipid Metabolism and VLDL Secretion in Mice
Liang Sheng, Yan Liu, Lin Jiang, Zheng Chen, Yingjiang Zhou, Kae Won Cho, Liangyou Rui
PLoS One. 2013; 8(12): e83269. Published online 2013 Dec 17. doi: 10.1371/journal.pone.0083269
PMCID:
PMC3866185
AbstractArticlePDF–2.8M
16.
Phosphorylation of the adaptor protein SH2B1β regulates its ability to enhance growth hormone-dependent macrophage motility
Hsiao-Wen Su, Nathan J. Lanning, David L. Morris, Lawrence S. Argetsinger, Carey N. Lumeng, Christin Carter-Su
J Cell Sci. 2013 Apr 15; 126(8): 1733–1743. doi: 10.1242/jcs.113050
PMCID:
PMC3678408
AbstractArticle
17.
The SH2B1 Adaptor Protein Associates with a Proximal Region of the Erythropoietin Receptor
Mojib Javadi, Edda Hofstätter, Natalie Stickle, Bryan K. Beattie, Robert Jaster, Christin Carter-Su, Dwayne L. Barber
J Biol Chem. 2012 Jul 27; 287(31): 26223–26234. Published online 2012 Jun 5. doi: 10.1074/jbc.M112.382721
PMCID:
PMC3406707
AbstractArticlePDF–1.9M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Identification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number
Nathan J. Lanning, Hsiao-Wen Su, Lawrence S. Argetsinger, Christin Carter-Su
J Cell Sci. 2011 Sep 15; 124(18): 3095–3105. doi: 10.1242/jcs.081547
PMCID:
PMC3172186
AbstractArticle
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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