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Select item 101544581.

SNAP23 decreases insulin secretion by competitively inhibiting the interaction between SNAP25 and STX1A

Jun Chen, Ziyan Wang, Tuanlao Wang, Jidong Cheng, Ruijuan Zhuang, Wei Wang

Biosci Rep. 2023 May 31; 43(5): BSR20222594. Published online 2023 Apr 28. doi: 10.1042/BSR20222594

PMCID:: PMC10154458

Abstract Article PDF–3.4M

Select item 94923472.

Striatal Syntaxin 1A Is Associated with Development of Tourette Syndrome in an Iminodipropionitrile-Induced Animal Model

Liu Yang, Xueming Wang, Xiumei Liu, Xin Chen

Dis Markers. 2022; 2022: 1148191. Published online 2022 Sep 14. doi: 10.1155/2022/1148191

PMCID:: PMC9492347

Abstract Article PDF–564K

Select item 87083123.

CK2 Phosphorylation Is Required for Regulation of Syntaxin 1A Activity in Ca²⁺-Triggered Release in Neuroendocrine Cells

Noa Barak-Broner, Dafna Singer-Lahat, Dodo Chikvashvili, Ilana Lotan

Int J Mol Sci. 2021 Dec; 22(24): 13556. Published online 2021 Dec 17. doi: 10.3390/ijms222413556

PMCID:: PMC8708312

Abstract Article PDF–3.3M

Select item 86705174.

Munc18-dependent and -independent clustering of syntaxin in the plasma membrane of cultured endocrine cells

Lei Wan, Xi Chen, Wolfhard Almers

Proc Natl Acad Sci U S A. 2021 Dec 7; 118(49): e2025748118. Published online 2021 Dec 2. doi: 10.1073/pnas.2025748118

PMCID:: PMC8670517

Abstract Article PDF–1.2M

Select item 86294285.

The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions

Jasmin Mertins, Jérôme Finke, Ricarda Sies, Kerstin M Rink, Jan Hasenauer, Thorsten Lang

eLife. 2021; 10: e69236. Published online 2021 Nov 15. doi: 10.7554/eLife.69236

PMCID:: PMC8629428

Abstract Article PDF–8.2M

Select item 79108906.

Syntaxin 1A Gene Is Negatively Regulated in a Cell/Tissue Specific Manner by YY1 Transcription Factor, Which Binds to the −183 to −137 Promoter Region Together with Gene Silencing Factors Including Histone Deacetylase

Takahiro Nakayama, Toshiyuki Fukutomi, Yasuo Terao, Kimio Akagawa

Biomolecules. 2021 Feb; 11(2): 146. Published online 2021 Jan 23. doi: 10.3390/biom11020146

PMCID:: PMC7910890

Abstract Article PDF–1.4M

Select item 73638317.

Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly

Sanghwa Lee, Jonghyeok Shin, Younghun Jung, Heyjin Son, Jaeil Shin, Cherlhyun Jeong, Dae-Hyuk Kweon, Yeon-Kyun Shin

Sci Rep. 2020; 10: 11623. Published online 2020 Jul 15. doi: 10.1038/s41598-020-68476-3

PMCID:: PMC7363831

Abstract Article PDF–1.4M

Select item 72555238.

Re‐examining how Munc13‐1 facilitates opening of syntaxin‐1

Magdalena Magdziarek, Agnieszka A. Bolembach, Karolina P. Stepien, Bradley Quade, Xiaoxia Liu, Josep Rizo

Protein Sci. 2020 Jun; 29(6): 1440–1458. Published online 2020 Mar 7. doi: 10.1002/pro.3844

PMCID:: PMC7255523

Abstract Article PDF–3.6M

Select item 67583779.

Regulation of Exocytosis through Ca²⁺/ATP-Dependent Binding of Autophosphorylated Ca²⁺/Calmodulin-Activated Protein Kinase II to Syntaxin 1A

Akihiro Ohyama, Kohei Hosaka, Yoshiaki Komiya, Kimio Akagawa, Emiko Yamauchi, Hisaaki Taniguchi, Nobuyuki Sasagawa, Konosuke Kumakura, Sumiko Mochida, Takashi Yamauchi, Michihiro Igarashi

J Neurosci. 2002 May 1; 22(9): 3342–3351. doi: 10.1523/JNEUROSCI.22-09-03342.2002

Correction in:: J Neurosci. 2002 Jul 1; 22(13): 5789.

PMCID:: PMC6758377

Abstract Article PDF–401K

Select item 674078010.

Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

Gustavo Pigino, Gerardo Morfini, Alejandra Pelsman, Mark P. Mattson, Scott T. Brady, Jorge Busciglio

J Neurosci. 2003 Jun 1; 23(11): 4499–4508. doi: 10.1523/JNEUROSCI.23-11-04499.2003

PMCID:: PMC6740780

Abstract Article PDF–383K

Select item 670580511.

The Dual Function of the Polybasic Juxtamembrane Region of Syntaxin 1A in Clamping Spontaneous Release and Stimulating Ca²⁺-Triggered Release in Neuroendocrine Cells

Dafna Singer-Lahat, Noa Barak-Broner, Anton Sheinin, Dafna Greitzer-Antes, Izhak Michaelevski, Ilana Lotan

J Neurosci. 2018 Jan 3; 38(1): 220–231. doi: 10.1523/JNEUROSCI.1541-17.2017

PMCID:: PMC6705805

Abstract Article PDF–2.8M

Select item 668176012.

Defining the Kv2.1–syntaxin molecular interaction identifies a first-in-class small molecule neuroprotectant

Chung-Yang Yeh, Zhaofeng Ye, Aubin Moutal, Shivani Gaur, Amanda M. Henton, Stylianos Kouvaros, Jami L. Saloman, Karen A. Hartnett-Scott, Thanos Tzounopoulos, Rajesh Khanna, Elias Aizenman, Carlos J. Camacho

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15696–15705. Published online 2019 Jul 15. doi: 10.1073/pnas.1903401116

PMCID:: PMC6681760

Abstract Article PDF–2.4M

Select item 667374713.

K⁺ Channel Facilitation of Exocytosis by Dynamic Interaction with Syntaxin

Dafna Singer-Lahat, Anton Sheinin, Dodo Chikvashvili, Sharon Tsuk, Dafna Greitzer, Reut Friedrich, Lori Feinshreiber, Uri Ashery, Morris Benveniste, Edwin S. Levitan, Ilana Lotan

J Neurosci. 2007 Feb 14; 27(7): 1651–1658. doi: 10.1523/JNEUROSCI.4006-06.2007

PMCID:: PMC6673747

Abstract Article PDF–390K

Select item 667109514.

Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis

Niranjana D. Amin, Ya-Li Zheng, Sashi Kesavapany, Jyotshnabala Kanungo, Tad Guszczynski, Ram K. Sihag, Parvathi Rudrabhatla, Wayne Albers, Philip Grant, Harish C. Pant

J Neurosci. 2008 Apr 2; 28(14): 3631–3643. doi: 10.1523/JNEUROSCI.0453-08.2008

PMCID:: PMC6671095

Abstract Article PDF–774K

Select item 662380415.

Syntaxin1A Lateral Diffusion Reveals Transient and Local SNARE Interactions

Claire Ribrault, Jürgen Reingruber, Maja Petković, Thierry Galli, Noam E. Ziv, David Holcman, Antoine Triller

J Neurosci. 2011 Nov 30; 31(48): 17590–17602. doi: 10.1523/JNEUROSCI.4065-11.2011

PMCID:: PMC6623804

Abstract Article PDF–2.5M

Select item 661853516.

Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability

Marife Arancillo, Sang-Won Min, Stefan Gerber, Agnieszka Münster-Wandowski, Yuan-Ju Wu, Melissa Herman, Thorsten Trimbuch, Jong-Cheol Rah, Gudrun Ahnert-Hilger, Dietmar Riedel, Thomas C. Südhof, Christian Rosenmund

J Neurosci. 2013 Oct 16; 33(42): 16698–16714. doi: 10.1523/JNEUROSCI.0187-13.2013

PMCID:: PMC6618535

Abstract Article PDF–4.4M

Select item 660187917.

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons

Gülçin Vardar, Shuwen Chang, Marife Arancillo, Yuan-Ju Wu, Thorsten Trimbuch, Christian Rosenmund

J Neurosci. 2016 Jul 27; 36(30): 7911–7924. doi: 10.1523/JNEUROSCI.1314-16.2016

PMCID:: PMC6601879

Abstract Article PDF–3.9M

Select item 624982718.

Syntaxin clusters at secretory granules in a munc18-bound conformation

Peng Yin, Nikhil R. Gandasi, Swati Arora, Muhmmad Omar-Hmeadi, Jan Saras, Sebastian Barg

Mol Biol Cell. 2018 Nov 1; 29(22): 2700–2708. doi: 10.1091/mbc.E17-09-0541

PMCID:: PMC6249827

Abstract Article PDF–3.2M

Select item 623727219.

The SNARE protein, syntaxin1a, plays an essential role in biphasic exocytosis of the incretin hormone, glucagon-like peptide-1

Sarah E. Wheeler, Holly M. Stacey, Yasaman Nahaei, Stephen J. Hale, Alexandre B. Hardy, Frank Reimann, Fiona M. Gribble, Pierre Larraufie, Herbert Y. Gaisano, Patricia L. Brubaker

Diabetes. Author manuscript; available in PMC 2018 Nov 15.

Published in final edited form as: Diabetes. 2017 Sep; 66(9): 2327–2338. Published online 2017 Jun 8. doi: 10.2337/db16-1403