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Select item 79711321.

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice

Jitendra Badhai, Gaurav Kumar Pandey, Ji-Ying Song, Oscar Krijgsman, Rajith Bhaskaran, Gayathri Chandrasekaran, Min-chul Kwon, Lorenzo Bombardelli, Kim Monkhorst, Cristoforo Grasso, John Zevenhoven, Jan van der Vliet, Miranda Cozijnsen, Paul Krimpenfort, Daniel Peeper, Maarten van Lohuizen, Anton Berns

J Exp Med. 2020 Jun 1; 217(6): e20191257. Published online 2020 Apr 9. doi: 10.1084/jem.20191257

PMCID:: PMC7971132

Abstract Article PDF–3.7M

Select item 66738722.

Temporal Control of Rac in Schwann Cell–Axon Interaction Is Disrupted in NF2-Mutant Schwannoma Cells

Yoko Nakai, Yi Zheng, Mia MacCollin, Nancy Ratner

J Neurosci. 2006 Mar 29; 26(13): 3390–3395. doi: 10.1523/JNEUROSCI.4865-05.2006

PMCID:: PMC6673872

Abstract Article PDF–1.3M

Select item 66735883.

p19^Ink4d and p21^Cip1 Collaborate to Maintain the Postmitotic State of Auditory Hair Cells, Their Codeletion Leading to DNA Damage and p53-Mediated Apoptosis

Heidi Laine, Angelika Doetzlhofer, Johanna Mantela, Jukka Ylikoski, Marikki Laiho, Martine F. Roussel, Neil Segil, Ulla Pirvola

J Neurosci. 2007 Feb 7; 27(6): 1434–1444. doi: 10.1523/JNEUROSCI.4956-06.2007

PMCID:: PMC6673588

Abstract Article PDF–605K

Select item 60073974.

Targeted next-generation sequencing for differential diagnosis of neurofibromatosis type 2, schwannomatosis, and meningiomatosis

Camille Louvrier, Eric Pasmant, Audrey Briand-Suleau, Joëlle Cohen, Patrick Nitschké, Juliette Nectoux, Lucie Orhant, Cécile Zordan, Cyril Goizet, Stéphane Goutagny, Dominique Lallemand, Michel Vidaud, Dominique Vidaud, Michel Kalamarides, Béatrice Parfait

Neuro Oncol. 2018 Jun; 20(7): 917–929. Published online 2018 Feb 2. doi: 10.1093/neuonc/noy009

PMCID:: PMC6007397

Abstract Article PDF–1.1M

Select item 59274475.

NF2 signaling pathway plays a pro-apoptotic role in β-adrenergic receptor stimulated cardiac myocyte apoptosis

Suman Dalal, Barbara Connelly, Mahipal Singh, Krishna Singh

PLoS One. 2018; 13(4): e0196626. Published online 2018 Apr 30. doi: 10.1371/journal.pone.0196626

PMCID:: PMC5927447

Abstract Article PDF–2.7M

Select item 59263006.

Allelic Loss of 14q and 22q, NF2 Mutation, and Genetic Instability Occur Independently of c‐kit Mutation in Gastrointestinal Stromal Tumor

Tomoki Fukasawa, Ja‐Mun Chong, Shinji Sakurai, Naoki Koshiishi, Rie Ikeno, Akira Tanaka, Yoshiro Matsumoto, Yukiko Hayashi, Morio Koike, Masashi Fukayama

Jpn J Cancer Res. 2000 Dec; 91(12): 1241–1249. doi: 10.1111/j.1349-7006.2000.tb00910.x

PMCID:: PMC5926300

Summary PDF–113K

Select item 54232027.

Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma

Mayura Meerang, Karima Bérard, Martina Friess, Byron K.Y. Bitanihirwe, Alex Soltermann, Bart Vrugt, Emanuela Felley-Bosco, Raphael Bueno, William G. Richards, Burkhardt Seifert, Rolf Stahel, Walter Weder, Isabelle Opitz

Mol Oncol. 2016 Oct; 10(8): 1255–1265. Published online 2016 Jun 25. doi: 10.1016/j.molonc.2016.06.005

PMCID:: PMC5423202

Abstract Article PDF–1.8M

Select item 46336348.

A splicing variant of Merlin promotes metastasis in hepatocellular carcinoma

Zai-Li Luo, Shu-Qun Cheng, Jie Shi, Hui-Lu Zhang, Cun-Zhen Zhang, Hai-Yang Chen, Bi-Jun Qiu, Liang Tang, Cong-Li Hu, Hong-Yang Wang, Zhong Li

Nat Commun. 2015; 6: 8457. Published online 2015 Oct 7. doi: 10.1038/ncomms9457

PMCID:: PMC4633634

Abstract Article PDF–3.1M

Select item 42975559.

Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development

Yelda Serinagaoglu, Joshua Paré, Marco Giovannini, Xinwei Cao

Dev Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Dev Biol. 2015 Feb 1; 398(1): 97–109. Published online 2014 Nov 26. doi: 10.1016/j.ydbio.2014.11.017

PMCID:: PMC4297555

Abstract Article PDF–2.6M

Select item 373771510.

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

Alfonso Lavado, Yu He, Joshua Paré, Geoffrey Neale, Eric N. Olson, Marco Giovannini, Xinwei Cao

Development. 2013 Aug 15; 140(16): 3323–3334. doi: 10.1242/dev.096537

PMCID:: PMC3737715

Abstract Article

Select item 346248111.

Endothelial Cdkn1a (p21) Overexpression and Accelerated Senescence in a Mouse Model of Fuchs Endothelial Corneal Dystrophy

Mario Matthaei, Huan Meng, Alan K. Meeker, Charles G. Eberhart, Albert S. Jun

Invest Ophthalmol Vis Sci. 2012 Sep; 53(10): 6718–6727. Published online 2012 Sep 28. doi: 10.1167/iovs.12-9669

PMCID:: PMC3462481

Abstract Article PDF–678K

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312959613.

SCHWANNOMIN/MERLIN PROMOTES SCHWANN CELL ELONGATION AND INFLUENCES MYELIN SEGMENT LENGTH

Courtney Thaxton, Marga Bott, Barbara Walker, Nicklaus A. Sparrow, Stephen Lambert, Cristina Fernandez-Valle

Mol Cell Neurosci. Author manuscript; available in PMC 2012 May 1.

Published in final edited form as: Mol Cell Neurosci. 2011 May; 47(1): 1–9. Published online 2010 Dec 21. doi: 10.1016/j.mcn.2010.12.006

PMCID:: PMC3129596

Abstract Article PDF–1.2M

Select item 307555214.

A Tight Junction-Associated Merlin-Angiomotin Complex Mediates Merlin’s Regulation of Mitogenic Signaling and Tumor Suppressive Functions

Chunling Yi, Scott Troutman, Daniela Fera, Anat Stemmer-Rachamimov, Jacqueline L. Avila, Neepa Christian, Nathalie Luna Persson, Akihiko Shimono, David W. Speicher, Ronen Marmorstein, Lars Holmgren, Joseph L. Kissil

Cancer Cell. Author manuscript; available in PMC 2012 Apr 12.

Published in final edited form as: Cancer Cell. 2011 Apr 12; 19(4): 527–540. doi: 10.1016/j.ccr.2011.02.017

PMCID:: PMC3075552

Abstract Article PDF–3.4M

Select item 290401315.

The Tumor Suppressor Merlin Is Required for Cell Cycle Exit, Terminal Differentiation, and Cell Polarity in the Developing Murine Lens

Luke A. Wiley, Lisa K. Dattilo, Kai B. Kang, Marco Giovannini, David C. Beebe

Invest Ophthalmol Vis Sci. 2010 Jul; 51(7): 3611–3618. doi: 10.1167/iovs.09-4371

PMCID:: PMC2904013

Abstract Article PDF–700K

Select item 285856216.

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

Jianzhong Yu, Yonggang Zheng, Jixin Dong, Stephen Klusza, Wu-Min Deng, Duojia Pan

Dev Cell. Author manuscript; available in PMC 2010 Aug 16.

Published in final edited form as: Dev Cell. 2010 Feb 16; 18(2): 288–299. doi: 10.1016/j.devcel.2009.12.012

PMCID:: PMC2858562

Abstract Article PDF–5.6M

Select item 282895317.

Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4^DCAF1 in the Nucleus

Wei Li, Liru You, Jonathan Cooper, Gaia Schiavon, Angela Pepe-Caprio, Lu Zhou, Ryohei Ishii, Marco Giovannini, C. Oliver Hanemann, Stephen B. Long, Hediye Erdjument-Bromage, Pengbo Zhou, Paul Tempst, Filippo G. Giancotti

Cell. Author manuscript; available in PMC 2011 Feb 19.

Published in final edited form as: Cell. 2010 Feb 19; 140(4): 477–490. doi: 10.1016/j.cell.2010.01.029

PMCID:: PMC2828953

Abstract Article PDF–4.5M

Select item 270099618.

Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma

Zachary S. Morris, Andrea I. McClatchey

Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24): 9767–9772. Published online 2009 Jun 1. doi: 10.1073/pnas.0902031106

PMCID:: PMC2700996

Abstract Article PDF–1.3M

Select item 182050619.

Identification and Characterization of Putative Tumor Suppressor NGB, a GTP-Binding Protein That Interacts with the Neurofibromatosis 2 Protein

Hansoo Lee, Donghwa Kim, Han C. Dan, Eric L. Wu, Tatiana M. Gritsko, Chuanhai Cao, Santo V. Nicosia, Erica A. Golemis, Wanguo Liu, Domenico Coppola, Steven S. Brem, Joseph R. Testa, Jin Q. Cheng

Mol Cell Biol. 2007 Mar; 27(6): 2103–2119. Published online 2007 Jan 8. doi: 10.1128/MCB.00572-06