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Items: 1 to 20 of 243

1.
Single-cell morphometrics reveals T-box gene-dependent patterns of epithelial tension in the Second Heart field
Clara Guijarro, Solène Song, Benoit Aigouy, Raphaël Clément, Paul Villoutreix, Robert G. Kelly
Nat Commun. 2024; 15: 9512. Published online 2024 Nov 4. doi: 10.1038/s41467-024-53612-8
PMCID:
PMC11535409
AbstractArticlePDF–8.7M
2.
Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models
Yang Li, Ke Ma, Zhujun Dong, Shijuan Gao, Jing Zhang, Shan Huang, Jie Yang, Guangming Fang, Yujie Li, Xiaowei Li, Carrie Welch, Emily L. Griffin, Prema Ramaswamy, Zaheer Valivullah, Xiuying Liu, Jianzeng Dong, Dao Wen Wang, Du, Wendy K. Chung, Yulin Li
J Clin Invest. 2024 Jun 17; 134(12): e177172. Published online 2024 Jun 17. doi: 10.1172/JCI177172
PMCID:
PMC11178530
AbstractArticlePDF–15M
3.
Tgfbr1 controls developmental plasticity between the hindlimb and external genitalia by remodeling their regulatory landscape
Anastasiia Lozovska, Artemis G. Korovesi, André Dias, Alexandre Lopes, Donald A. Fowler, Gabriel G. Martins, Ana Nóvoa, Moisés Mallo
Nat Commun. 2024; 15: 2509. Published online 2024 Mar 20. doi: 10.1038/s41467-024-46870-z
PMCID:
PMC10954616
AbstractArticlePDF–9.6M
4.
A single-cell time-lapse of mouse prenatal development from gastrula to birth
Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure
Nature. 2024; 626(8001): 1084–1093. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07069-w
PMCID:
PMC10901739
AbstractArticlePDF–63M
5.
Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network
Mason E. Sweat, Yangpo Cao, Xiaoran Zhang, Ozanna Burnicka-Turek, Carlos Perez-Cervantes, Kulandai Arulsamy, Fujian Lu, Erin M. Keating, Brynn N. Akerberg, Qing Ma, Hiroko Wakimoto, Joshua M. Gorham, Lauren D. Hill, Mi Kyoung Song, Michael A. Trembley, Peizhe Wang, Matteo Gianeselli, Maksymilian Prondzynski, Raul H. Bortolin, Vassilios J. Bezzerides, Kaifu Chen, Jonathan G. Seidman, Christine E. Seidman, Ivan P. Moskowitz, William T. Pu
Nat Cardiovasc Res. Author manuscript; available in PMC 2024 Apr 12.
Published in final edited form as: Nat Cardiovasc Res. 2023 Oct; 2(10): 881–898. Published online 2023 Oct 12. doi: 10.1038/s44161-023-00334-7
PMCID:
PMC10854392
AbstractArticlePDF–8.0M
6.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
7.
The Tbx20-TLE interaction is essential for the maintenance of the second heart field
Whitney Edwards, Olivia K. Bussey, Frank L. Conlon
Development. 2023 Nov 1; 150(21): dev201677. Published online 2023 Oct 30. doi: 10.1242/dev.201677
PMCID:
PMC10629681
AbstractArticle
8.
Acquisition of neural fate by combination of BMP blockade and chromatin modification
Agnes Lee Chen Ong, Toshiya Kokaji, Arisa Kishi, Yoshihiro Takihara, Takuma Shinozuka, Ren Shimamoto, Ayako Isotani, Manabu Shirai, Noriaki Sasai
iScience. 2023 Oct 20; 26(10): 107887. Published online 2023 Sep 9. doi: 10.1016/j.isci.2023.107887
Correction in:
iScience. 2023 Nov 17; 26(11): 108257.
PMCID:
PMC10522999
AbstractArticlePDF–6.7M
9.
CHARGE syndrome-associated CHD7 acts at ISL1-regulated enhancers to modulate second heart field gene expression
Athanasia Stathopoulou, Ping Wang, Charlotte Thellier, Robert G Kelly, Deyou Zheng, Peter J Scambler
Cardiovasc Res. 2023 Aug; 119(11): 2089–2105. Published online 2023 Apr 13. doi: 10.1093/cvr/cvad059
Correction in:
Cardiovasc Res. 2024 Jan; 120(1): 120.
PMCID:
PMC10478754
AbstractArticlePDF–21M
10.
USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities
Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji
Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888
PMCID:
PMC10191441
AbstractArticlePDF–2.4M
11.
Topologically associating domain boundaries are required for normal genome function
Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio
Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w
PMCID:
PMC10119121
AbstractArticlePDF–3.2M
12.
Cardiac progenitors instruct second heart field fate through Wnts
Matthew Miyamoto, Suraj Kannan, Matthew J. Anderson, Xihe Liu, David Suh, Myo Htet, Biyi Li, Tejasvi Kakani, Sean Murphy, Emmanouil Tampakakis, Mark Lewandoski, Peter Andersen, Hideki Uosaki, Chulan Kwon
Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2217687120. Published online 2023 Jan 17. doi: 10.1073/pnas.2217687120
PMCID:
PMC9942880
AbstractArticlePDF–2.0M
13.
An atrial fibrillation-associated regulatory region modulates cardiac Tbx5 levels and arrhythmia susceptibility
Fernanda M Bosada, Karel van Duijvenboden, Alexandra E Giovou, Mathilde R Rivaud, Jae-Sun Uhm, Arie O Verkerk, Bastiaan J Boukens, Vincent M Christoffels
eLife. 2023; 12: e80317. Published online 2023 Jan 30. doi: 10.7554/eLife.80317
PMCID:
PMC9928424
AbstractArticlePDF–6.6M
14.
Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment
Rasmani Hazra, Lily Brine, Libia Garcia, Brian Benz, Napon Chirathivat, Michael M. Shen, John Erby Wilkinson, Scott K. Lyons, David L. Spector
Dev Cell. Author manuscript; available in PMC 2023 Nov 7.
Published in final edited form as: Dev Cell. 2022 Nov 7; 57(21): 2450–2468.e7. doi: 10.1016/j.devcel.2022.10.002
PMCID:
PMC9680017
AbstractArticlePDF–2.9M
15.
The Transcription Factor Tbx5 Regulates Direction-Selective Retinal Ganglion Cell Development and Image Stabilization
Timour Al-Khindi, Michael Sherman, Takashi Kodama, Preethi Gopal, Zhiwei Pan, James Kiraly, Hao Zhang, Loyal A. Goff, Sascha du Lac, Alex L. Kolodkin
Curr Biol. Author manuscript; available in PMC 2023 Oct 10.
Published in final edited form as: Curr Biol. 2022 Oct 10; 32(19): 4286–4298.e5. Published online 2022 Aug 22. doi: 10.1016/j.cub.2022.07.064
PMCID:
PMC9560999
AbstractArticlePDF–1.2M
16.
NOTCH maintains developmental cardiac gene network through WNT5A
Yidong Wang, Pengfei Lu, Bingruo Wu, Bernice E. Morrow, Bin Zhou
J Mol Cell Cardiol. Author manuscript; available in PMC 2022 Oct 4.
Published in final edited form as: J Mol Cell Cardiol. 2018 Dec; 125: 98–105. Published online 2018 Oct 19. doi: 10.1016/j.yjmcc.2018.10.014
PMCID:
PMC9531535
AbstractArticlePDF–1.3M
17.
devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data
Francisco X. Galdos, Sidra Xu, William R. Goodyer, Lauren Duan, Yuhsin V. Huang, Soah Lee, Han Zhu, Carissa Lee, Nicholas Wei, Daniel Lee, Sean M. Wu
Nat Commun. 2022; 13: 5271. Published online 2022 Sep 7. doi: 10.1038/s41467-022-33045-x
PMCID:
PMC9452519
AbstractArticlePDF–10M
18.
Maternal nicotine exposure induces congenital heart defects in the offspring of mice
Elizabeth R. Greco, Anish Engineer, Tana Saiyin, Xiangru Lu, MengQi Zhang, Douglas L. Jones, Qingping Feng
J Cell Mol Med. 2022 Jun; 26(11): 3223–3234. Published online 2022 May 6. doi: 10.1111/jcmm.17328
PMCID:
PMC9170818
AbstractArticlePDF–4.0M
19.
CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart
Zachary L. Robbe, Wei Shi, Lauren K. Wasson, Angel P. Scialdone, Caralynn M. Wilczewski, Xinlei Sheng, Austin J. Hepperla, Brynn N. Akerberg, William T. Pu, Ileana M. Cristea, Ian J. Davis, Frank L. Conlon
Genes Dev. 2022 Apr 1; 36(7-8): 468–482. doi: 10.1101/gad.349154.121
PMCID:
PMC9067406
AbstractArticlePDF–8.4M
20.
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen
Circulation. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: Circulation. 2022 Feb 22; 145(8): 586–602. Published online 2021 Dec 17. doi: 10.1161/CIRCULATIONAHA.121.056666
PMCID:
PMC8860879
AbstractArticlePDF–2.5M

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