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Select item 114156001.

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun

Life Sci Alliance. 2024 Dec; 7(12): e202402719. Published online 2024 Sep 20. doi: 10.26508/lsa.202402719

PMCID:: PMC11415600

Abstract Article PDF–5.1M

Select item 112177832.

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114149. Published online 2024 Apr 26. doi: 10.1016/j.celrep.2024.114149

PMCID:: PMC11217783

Abstract Article PDF–3.2M

Select item 112084433.

Thrombospondin-4 deletion does not exacerbate muscular dystrophy in β-sarcoglycan-deficient and laminin α2 chain-deficient mice

Paula Zarén, Kinga I. Gawlik

Sci Rep. 2024; 14: 14757. Published online 2024 Jun 26. doi: 10.1038/s41598-024-65473-8

PMCID:: PMC11208443

Abstract Article PDF–10M

Select item 103078524.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102183685.

Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction

Sarah N. Lipp, Kathryn R. Jacobson, Haley A. Colling, Tyler G. Tuttle, Dalton T. Miles, Kaitlin P. McCreery, Sarah Calve

Matrix Biol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Matrix Biol. 2023 Feb; 116: 28–48. Published online 2023 Jan 26. doi: 10.1016/j.matbio.2023.01.003

PMCID:: PMC10218368

Abstract Article PDF–2.2M

Select item 93760146.

Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex

Xiaoping Wu, Alexander A. Sosunov, Wudu Lado, Jia Jie Teoh, Ahrom Ham, Hongyu Li, Osama Al-Dalahmah, Brian J.A. Gill, Ottavio Arancio, Catherine A. Schevon, Wayne N. Frankel, Guy M. McKhann, II, David Sulzer, James E. Goldman, Guomei Tang

Cell Rep. Author manuscript; available in PMC 2022 Aug 14.

Published in final edited form as: Cell Rep. 2022 Jul 19; 40(3): 111085. doi: 10.1016/j.celrep.2022.111085

PMCID:: PMC9376014

Abstract Article PDF–4.2M

Select item 88608797.

PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle

Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen

Circulation. Author manuscript; available in PMC 2023 Feb 22.

Published in final edited form as: Circulation. 2022 Feb 22; 145(8): 586–602. Published online 2021 Dec 17. doi: 10.1161/CIRCULATIONAHA.121.056666

PMCID:: PMC8860879

Abstract Article PDF–2.5M

Select item 78936428.

TBX1 is required for normal stria vascularis and semicircular canal development

Cong Tian, Kenneth R. Johnson

Dev Biol. Author manuscript; available in PMC 2021 Feb 19.

Published in final edited form as: Dev Biol. 2020 Jan 1; 457(1): 91–103. Published online 2019 Sep 21. doi: 10.1016/j.ydbio.2019.09.013

PMCID:: PMC7893642

Abstract Article PDF–3.5M

Select item 69783499.

Effects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages

Mohammed Tanjimur Rahman, Santoshi Muppala, Jiahui Wu, Irene Krukovets, Dmitry Solovjev, Dmitriy Verbovetskiy, Chioma Obiako, Edward F. Plow, Olga Stenina-Adognravi

Cell Death Dis. 2020 Jan; 11(1): 53. Published online 2020 Jan 23. doi: 10.1038/s41419-020-2237-2

PMCID:: PMC6978349

Abstract Article PDF–1.8M

Select item 658966410.

Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment

Kathlyn J. Gan, Thomas C. Südhof

Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12524–12533. Published online 2019 Jun 3. doi: 10.1073/pnas.1902672116

PMCID:: PMC6589664

Abstract Article PDF–2.6M

Select item 637596611.

Overlapping and differential functions of ATF6α versus ATF6β in the mouse heart

Robert N. Correll, Kelly M. Grimes, Vikram Prasad, Jeffrey M. Lynch, Hadi Khalil, Jeffery D. Molkentin

Sci Rep. 2019; 9: 2059. Published online 2019 Feb 14. doi: 10.1038/s41598-019-39515-5

PMCID:: PMC6375966

Abstract Article PDF–1.7M

Select item 632514312.

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability

Tobias G. Schips, Davy Vanhoutte, Alexander Vo, Robert N. Correll, Matthew J. Brody, Hadi Khalil, Jason Karch, Andoria Tjondrokoesoemo, Michelle A. Sargent, Marjorie Maillet, Robert S. Ross, Jeffery D. Molkentin

Nat Commun. 2019; 10: 76. Published online 2019 Jan 8. doi: 10.1038/s41467-018-08026-8

PMCID:: PMC6325143

Abstract Article PDF–5.3M

Select item 602416313.

Defective Flux of Thrombospondin-4 through the Secretory Pathway Impairs Cardiomyocyte Membrane Stability and Causes Cardiomyopathy

Matthew J. Brody, Davy Vanhoutte, Tobias G. Schips, Justin G. Boyer, Chinmay V. Bakshi, Michelle A. Sargent, Allen J. York, Jeffery D. Molkentin

Mol Cell Biol. 2018 Jul 15; 38(14): e00114-18. Prepublished online 2018 Apr 30. Published online 2018 Jun 28. doi: 10.1128/MCB.00114-18

PMCID:: PMC6024163

Abstract Article PDF–2.6M

Select item 598760614.

Gene expression profiling in the developing secondary palate in the absence of Tbx1 function

Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno, Martyn T. Cobourne

BMC Genomics. 2018; 19: 429. Published online 2018 Jun 4. doi: 10.1186/s12864-018-4782-y

PMCID:: PMC5987606

Abstract Article PDF–2.6M

Select item 568123715.

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety

Lee Moir, Elena G. Bochukova, Rebecca Dumbell, Gareth Banks, Rasneer S. Bains, Patrick M. Nolan, Cheryl Scudamore, Michelle Simon, Kimberly A. Watson, Julia Keogh, Elana Henning, Audrey Hendricks, Stephen O'Rahilly, Inês Barroso, UK10K consortium, Adrienne E. Sullivan, David C. Bersten, Murray L. Whitelaw, Susan Kirsch, Elizabeth Bentley, I. Sadaf Farooqi, Roger D. Cox

Mol Metab. 2017 Nov; 6(11): 1419–1428. Published online 2017 Aug 24. doi: 10.1016/j.molmet.2017.08.006

PMCID:: PMC5681237

Abstract Article PDF–3.0M

Select item 558949416.

Thrombospondin-4 mediates TGF-ß-induced angiogenesis

Santoshi Muppala, Roy Xiao, Irene Krukovets, Dmitry Verbovetsky, Revanth Yendamuri, Nayab Habib, Priya Raman, Edward Plow, Olga Stenina-Adognravi

Oncogene. Author manuscript; available in PMC 2017 Nov 8.

Published in final edited form as: Oncogene. 2017 Sep 7; 36(36): 5189–5198. Published online 2017 May 8. doi: 10.1038/onc.2017.140

PMCID:: PMC5589494

Abstract Article PDF–1.2M

Select item 541430917.

Increased thrombospondin-4 after nerve injury mediates disruption of intracellular calcium signaling in primary sensory neurons

Yuan Guo, Zhiyong Zhang, Hsiang-en Wu, Z. David Luo, Quinn H. Hogan, Bin Pan

Neuropharmacology. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Neuropharmacology. 2017 May 1; 117: 292–304. Published online 2017 Feb 22. doi: 10.1016/j.neuropharm.2017.02.019

PMCID:: PMC5414309

Abstract Article PDF–1.3M

Select item 506358818.

Thrombospondin expression in myofibers stabilizes muscle membranes

Davy Vanhoutte, Tobias G Schips, Jennifer Q Kwong, Jennifer Davis, Andoria Tjondrokoesoemo, Matthew J Brody, Michelle A Sargent, Onur Kanisicak, Hong Yi, Quan Q Gao, Joseph E Rabinowitz, Talila Volk, Elizabeth M McNally, Jeffery D Molkentin

eLife. 2016; 5: e17589. Published online 2016 Sep 26. doi: 10.7554/eLife.17589

PMCID:: PMC5063588

Abstract Article PDF–5.8M

Select item 500753219.

Assessing the contribution of thrombospondin-4 induction and ATF6α activation to endoplasmic reticulum expansion and phenotypic modulation in bladder outlet obstruction

Katarzyna K. Krawczyk, Mari Ekman, Catarina Rippe, Mario Grossi, Bengt-Olof Nilsson, Sebastian Albinsson, Bengt Uvelius, Karl Swärd

Sci Rep. 2016; 6: 32449. Published online 2016 Sep 1. doi: 10.1038/srep32449

PMCID:: PMC5007532

Abstract Article PDF–3.1M

Select item 498892320.

Thrombospondin-4 divergently regulates voltage gated Ca²⁺ channel subtypes in sensory neurons after nerve injury

Bin Pan, Yuan Guo, Hsiang-En Wu, John Park, Van Nancy Trinh, Z. David Luo, Quinn H. Hogan

Pain. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Pain. 2016 Sep; 157(9): 2068–2080. doi: 10.1097/j.pain.0000000000000612

PMCID:: PMC4988923

Abstract Article PDF–2.9M

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