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Items: 1 to 20 of 26

1.
Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event
Allison J. Greaney, Makayla K. Portley, Danielle O’Mard, Devorah Crown, Nolan K. Maier, Megan A. Mendenhall, Katrin D. Mayer-Barber, Stephen H. Leppla, Mahtab Moayeri
J Leukoc Biol. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: J Leukoc Biol. 2020 Sep; 108(3): 773–786. Published online 2020 May 18. doi: 10.1002/JLB.4HI0320-028R
PMCID:
PMC11062252
AbstractArticlePDF–1.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Autophagy dysfunction contributes to NLRP1 inflammasome-linked depressive-like behaviors in mice
Ya-Jing Zhu, Jing Huang, Ru Chen, Yu Zhang, Xin He, Wen-Xin Duan, Yuan-Lei Zou, Meng-Mei Sun, Hui-Li Sun, Si-Min Cheng, Hao-Chuan Wang, Hao Zhang, Wen-Ning Wu
J Neuroinflammation. 2024; 21: 6. Published online 2024 Jan 4. doi: 10.1186/s12974-023-02995-4
PMCID:
PMC10765763
AbstractArticlePDF–12M
4.
Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib
Kun Chen, Jing Fan, Zhao-Fan Luo, Ying Yang, Wen-Jun Xin, Cui-Cui Liu
J Neuroinflammation. 2018; 15: 292. Published online 2018 Oct 20. doi: 10.1186/s12974-018-1327-x
PMCID:
PMC6195754
AbstractArticlePDF–1.5M
5.
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
Hazel Tye, Chien-Hsiung Yu, Lisa A. Simms, Marcel R. de Zoete, Man Lyang Kim, Martha Zakrzewski, Jocelyn S. Penington, Cassandra R. Harapas, Fernando Souza-Fonseca-Guimaraes, Leesa F. Wockner, Adele Preaudet, Lisa A. Mielke, Stephen A. Wilcox, Yasunori Ogura, Sinead C. Corr, Komal Kanojia, Konstantinos A. Kouremenos, David P. De Souza, Malcolm J. McConville, Richard A. Flavell, Motti Gerlic, Benjamin T. Kile, Anthony T. Papenfuss, Tracy L. Putoczki, Graham L. Radford-Smith, Seth L. Masters
Nat Commun. 2018; 9: 3728. Published online 2018 Sep 13. doi: 10.1038/s41467-018-06125-0
PMCID:
PMC6137172
AbstractArticlePDF–1.4M
6.
Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling
Shenbin Liu, Qian Li, Meng-Ting Zhang, Qi-Liang Mao-Ying, Lang-Yue Hu, Gen-Cheng Wu, Wen-Li Mi, Yan-Qing Wang
Sci Rep. 2016; 6: 28956. Published online 2016 Jul 6. doi: 10.1038/srep28956
PMCID:
PMC4933926
AbstractArticlePDF–2.9M
7.
Nonessential Role for the NLRP1 Inflammasome Complex in a Murine Model of Traumatic Brain Injury
Thomas Brickler, Kisha Gresham, Armand Meza, Sheryl Coutermarsh-Ott, Tere M. Williams, Daniel E. Rothschild, Irving C. Allen, Michelle H. Theus
Mediators Inflamm. 2016; 2016: 6373506. Published online 2016 Apr 20. doi: 10.1155/2016/6373506
PMCID:
PMC4854993
AbstractArticlePDF–2.9M
8.
The NLRP1 Inflammasome Attenuates Colitis and Colitis-Associated Tumorigenesis
Tere M. Williams, Rachel A. Leeth, Daniel E. Rothschild, Sheryl L. Coutermarsh-Ott, Dylan K. McDaniel, Alysha E. Simmons, Bettina Heid, Thomas E. Cecere, Irving C. Allen
J Immunol. Author manuscript; available in PMC 2016 Apr 1.
Published in final edited form as: J Immunol. 2015 Apr 1; 194(7): 3369–3380. Published online 2015 Feb 27. doi: 10.4049/jimmunol.1402098
PMCID:
PMC4369420
AbstractArticlePDF–1.8M
9.
The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes
Nolan K. Maier, Stephen H. Leppla, Mahtab Moayeri
J Immunol. Author manuscript; available in PMC 2016 Mar 15.
Published in final edited form as: J Immunol. 2015 Mar 15; 194(6): 2776–2785. Published online 2015 Feb 13. doi: 10.4049/jimmunol.1401611
PMCID:
PMC4355055
AbstractArticlePDF–1.5M
10.
NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells
Seth L. Masters, Motti Gerlic, Donald Metcalf, Simon Preston, Marc Pellegrini, Joanne A. O’Donnell, Kate McArthur, Tracey M. Baldwin, Stephane Chevrier, Cameron J. Nowell, Louise H. Cengia, Katya J. Henley, Janelle E. Collinge, Daniel L. Kastner, Lionel Feigenbaum, Douglas J. Hilton, Warren S. Alexander, Benjamin T. Kile, Ben A. Croker
Immunity. Author manuscript; available in PMC 2014 Dec 23.
Published in final edited form as: Immunity. 2012 Dec 14; 37(6): 1009–1023. Published online 2012 Dec 6. doi: 10.1016/j.immuni.2012.08.027
PMCID:
PMC4275304
AbstractArticlePDF–3.5M
11.
Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma
Wei Chi, Fei Li, Hongrui Chen, Yandong Wang, Yingting Zhu, Xuejiao Yang, Jie Zhu, Frances Wu, Hong Ouyang, Jian Ge, Robert N. Weinreb, Kang Zhang, Yehong Zhuo
Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30): 11181–11186. Published online 2014 Jul 14. doi: 10.1073/pnas.1402819111
PMCID:
PMC4121847
AbstractArticlePDF–1.5M
12.
A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage
Pierre Cavailles, Pierre Flori, Olivier Papapietro, Cordelia Bisanz, Dominique Lagrange, Ludovic Pilloux, Céline Massera, Sara Cristinelli, Delphine Jublot, Olivier Bastien, Corinne Loeuillet, Delphine Aldebert, Bastien Touquet, Gilbert J. Fournié, Marie France Cesbron-Delauw
PLoS Pathog. 2014 Apr; 10(4): e1004005. Published online 2014 Apr 3. doi: 10.1371/journal.ppat.1004005
PMCID:
PMC3974857
AbstractArticlePDF–1.5M
13.
Dual Role for Inflammasome Sensors NLRP1 and NLRP3 in Murine Resistance to Toxoplasma gondii
Gezahegn Gorfu, Kimberly M. Cirelli, Mariane B. Melo, Katrin Mayer-Barber, Devorah Crown, Beverly H. Koller, Seth Masters, Alan Sher, Stephen H. Leppla, Mahtab Moayeri, Jeroen P. J. Saeij, Michael E. Grigg
mBio. 2014 Jan-Feb; 5(1): e01117-13. Published online 2014 Feb 18. doi: 10.1128/mBio.01117-13
PMCID:
PMC3944820
AbstractArticlePDF–2.7M
14.
NLRP1 Is an Inflammasome Sensor for Toxoplasma gondii
Sarah E. Ewald, Joseph Chavarria-Smith, John C. Boothroyd
Infect Immun. 2014 Jan; 82(1): 460–468. doi: 10.1128/IAI.01170-13
PMCID:
PMC3911858
AbstractArticlePDF–1.0M
15.
Arsenic trioxidesand other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes
Nolan K. Maier, Devorah Crown, Jie Liu, Stephen H. Leppla, Mahtab Moayeri
J Immunol. Author manuscript; available in PMC 2015 Jan 15.
Published in final edited form as: J Immunol. 2014 Jan 15; 192(2): 10.4049/jimmunol.1301434. Published online 2013 Dec 13. doi: 10.4049/jimmunol.1301434
PMCID:
PMC3884817
AbstractArticlePDF–1.1M
16.
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke
D Yang-Wei Fann, S-Y Lee, S Manzanero, S-C Tang, M Gelderblom, P Chunduri, C Bernreuther, M Glatzel, Y-L Cheng, J Thundyil, A Widiapradja, K-Z Lok, S L Foo, Y-C Wang, Y-I Li, G R Drummond, M Basta, T Magnus, D-G Jo, M P Mattson, C G Sobey, T V Arumugam
Cell Death Dis. 2013 Sep; 4(9): e790. Published online 2013 Sep 5. doi: 10.1038/cddis.2013.326
PMCID:
PMC3789184
AbstractArticlePDF–3.6M
17.
Transcriptional analysis of the three Nlrp1 paralogs in mice
Inka Sastalla, Devorah Crown, Seth L Masters, Andrew McKenzie, Stephen H Leppla, Mahtab Moayeri
BMC Genomics. 2013; 14: 188. Published online 2013 Mar 18. doi: 10.1186/1471-2164-14-188
PMCID:
PMC3641005
AbstractArticlePDF–1.5M
18.
NLRP1 dependent pyroptosis leads to acute lung injury and morbidity in mice
Martina Kovarova, Pamela R. Hesker, Leigh Jania, MyTrang Nguyen, John N. Snouwaert, Zhidan Xiang, Stephen E. Lommatzsch, Max T. Huang, Jenny P.-Y. Ting, Beverly H. Koller
J Immunol. Author manuscript; available in PMC 2013 Aug 15.
Published in final edited form as: J Immunol. 2012 Aug 15; 189(4): 2006–2016. Published online 2012 Jun 29. doi: 10.4049/jimmunol.1201065
PMCID:
PMC3635067
AbstractArticlePDF–2.5M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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