PMC Links for GEO Profiles (Select 117288231) - PMC

Xiaoyan Zeng, Stanley K. K. Cheung, Mengqi Shi, Penelope M. Y. Or, Zhining Li, Julia Y. H. Liu, Wayne L. H. Ho, Tian Liu, Kun Lu, John A. Rudd, Yubing Wang, Andrew M. Chan

J Neuroinflammation. 2023; 20: 290. Published online 2023 Dec 2. doi: 10.1186/s12974-023-02970-z

PMCID:: PMC10693711

Abstract Article PDF–11M

Select item 104152205.

Chitinase-3-like 1 regulates T_H2 cells, T_FH cells and IgE responses to helminth infection

Miranda L. Curtiss, Alexander F. Rosenberg, Christopher D. Scharer, Betty Mousseau, Natalia A. Ballesteros Benavides, John E. Bradley, Beatriz León, Chad Steele, Troy D. Randall, Frances E. Lund

Front Immunol. 2023; 14: 1158493. Published online 2023 Jul 27. doi: 10.3389/fimmu.2023.1158493

PMCID:: PMC10415220

Abstract Article PDF–5.6M

Select item 104099056.

E-cigarette exposure augments murine abdominal aortic aneurysm development: role of Chil1

Joscha Mulorz, Joshua M Spin, Pireyatharsheny Mulorz, Markus Udo Wagenhäuser, Alicia Deng, Karin Mattern, Yae H Rhee, Kensuke Toyama, Matti Adam, Hubert Schelzig, Lars Maegdefessel, Philip S Tsao

Cardiovasc Res. 2023 Mar; 119(3): 867–878. Published online 2022 Nov 22. doi: 10.1093/cvr/cvac173

PMCID:: PMC10409905

Abstract Article PDF–809K

Select item 103001837.

Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression

Andrea D. Kim, Lin Kui, Benedikt Kaufmann, Sung Eun Kim, Aleksandra Leszczynska, Ariel E. Feldstein

J Mol Med (Berl) 2023; 101(7): 813–828. Published online 2023 May 11. doi: 10.1007/s00109-023-02325-4

Correction in:: J Mol Med (Berl). 2023; 101(12): 1627.

PMCID:: PMC10300183

Abstract Article PDF–6.7M

Select item 102819728.

CHI3L1 induces autophagy through the JNK pathway in lung cancer cells

Da Eun Hong, Ji Eun Yu, Seung Sik Yoo, In Jun Yeo, Dong Ju Son, Jaesuk Yun, Sang-Bae Han, Jin Tae Hong

Sci Rep. 2023; 13: 9964. Published online 2023 Jun 20. doi: 10.1038/s41598-023-36844-4

PMCID:: PMC10281972

Abstract Article PDF–4.2M

Select item 98125609.

CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis

Bing Ma, Suchitra Kamle, Bedia Akosman, Hina Khan, Chang-Min Lee, Chun Geun Lee, Jack A. Elias

Front Immunol. 2022; 13: 1056397. Published online 2022 Dec 21. doi: 10.3389/fimmu.2022.1056397

PMCID:: PMC9812560

Abstract Article PDF–14M

Select item 970882010.

FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells

Matthew R. Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M. Ornitz, Herbert B. Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, Saverio Bellusci

Cell Mol Life Sci. 2022; 79(12): 609. Published online 2022 Nov 29. doi: 10.1007/s00018-022-04626-2

PMCID:: PMC9708820

Abstract Article PDF–3.1M

Select item 968234811.

Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer

Di Lu, Zuyuan Lin, Rui Wang, Zun Chen, Jianyong Zhuo, Li Xu, Linhui Pan, Huihui Li, Xinyu Yang, Chiyu He, Wei Shen, Modan Yang, Huigang Li, Hao Chen, Winyen Tan, Xuyong Wei, Shusen Zheng, Xiao Xu

Redox Biol. 2022 Dec; 58: 102538. Published online 2022 Nov 12. doi: 10.1016/j.redox.2022.102538

PMCID:: PMC9682348

Abstract Article PDF–9.4M

Select item 888264812.

Adenosine A2A Receptor Suppressed Astrocyte-Mediated Inflammation Through the Inhibition of STAT3/YKL-40 Axis in Mice With Chronic Cerebral Hypoperfusion-induced White Matter Lesions

Jichao Yuan, Lin Chen, Jie Wang, Simin Xia, Jialu Huang, Linke Zhou, Chengjian Feng, Xiaofei Hu, Zhenhua Zhou, Hong Ran

Front Immunol. 2022; 13: 841290. Published online 2022 Feb 14. doi: 10.3389/fimmu.2022.841290

Correction in:: Front Immunol. 2022; 13: 883172.

PMCID:: PMC8882648

Abstract Article PDF–30M

Select item 884832713.

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability

Pavlos Tsantilas, Shen Lao, Zhiyuan Wu, Anne Eberhard, Greg Winski, Monika Vaerst, Vivek Nanda, Ying Wang, Yoko Kojima, Jianqin Ye, Alyssa Flores, Kai-Uwe Jarr, Jaroslav Pelisek, Hans-Henning Eckstein, Ljubica Matic, Ulf Hedin, Philip S Tsao, Valentina Paloschi, Lars Maegdefessel, Nicholas J Leeper

Cardiovasc Res. 2021 Dec 1; 117(14): 2767–2780. Published online 2021 Feb 7. doi: 10.1093/cvr/cvab014

PMCID:: PMC8848327

Abstract Article PDF–1.5M

Select item 866355314.

Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19

Suchitra Kamle, Bing Ma, Chuan Hua He, Bedia Akosman, Yang Zhou, Chang-Min Lee, Wafik S. El-Deiry, Kelsey Huntington, Olin Liang, Jason T. Machan, Min-Jong Kang, Hyeon Jun Shin, Emiko Mizoguchi, Chun Geun Lee, Jack A. Elias

JCI Insight. 2021 Nov 8; 6(21): e148749. Published online 2021 Nov 8. doi: 10.1172/jci.insight.148749

PMCID:: PMC8663553

Abstract Article PDF–2.2M

Select item 855356015.

CHI3L1 regulates PD-L1 and anti–CHI3L1–PD-1 antibody elicits synergistic antitumor responses

Bing Ma, Bedia Akosman, Suchitra Kamle, Chang-Min Lee, Chuan Hua He, Ja Seok Koo, Chun Geun Lee, Jack A. Elias

J Clin Invest. 2021 Nov 1; 131(21): e137750. Published online 2021 Nov 1. doi: 10.1172/JCI137750

PMCID:: PMC8553560

Abstract Article PDF–15M

Select item 823815216.

Chitinase 3-like-1 protects airway function despite promoting type 2 inflammation during fungal-associated allergic airway inflammation

Joseph J. Mackel, Jaleesa M. Garth, MaryJane Jones, Diandra A. Ellis, Jonathan P. Blackburn, Zhihong Yu, Sadis Matalon, Miranda Curtiss, Frances E. Lund, Annette T. Hastie, Deborah A. Meyers, Chad Steele

Am J Physiol Lung Cell Mol Physiol. 2021 Apr 1; 320(4): L615–L626. Published online 2021 Feb 3. doi: 10.1152/ajplung.00528.2020

PMCID:: PMC8238152

Article

Select item 823303617.

Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment

Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju

eLife. 2021; 10: e68571. Published online 2021 Jun 10. doi: 10.7554/eLife.68571

PMCID:: PMC8233036

Abstract Article PDF–7.6M

Select item 790943818.

Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease

Songhua Zhang, Aryanna Sousa, Mengqui Lin, Ayako Iwano, Rishubh Jain, Bing Ma, Chang Min Lee, Jin Wook Park, Suchitra Kamle, Rolf Carlson, Ghun Geun Lee, Jack A. Elias, Jack R. Wands

Cells. 2021 Feb; 10(2): 201. Published online 2021 Jan 20. doi: 10.3390/cells10020201

PMCID:: PMC7909438

Abstract Article PDF–4.4M

Select item 780831319.

Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer Disease pathogenesis

Brian V. Lananna, Celia A. McKee, Melvin W. King, Jorge Del-Aguila, Julie M. Dimitry, Fabiana H. G. Farias, Collin J. Nadarajah, David D. Xiong, Chun Guo, Alex J. Cammack, Jack A. Elias, Jinsong Zhang, Carlos Cruchaga, Erik S. Musiek

Sci Transl Med. Author manuscript; available in PMC 2021 Dec 16.

Published in final edited form as: Sci Transl Med. 2020 Dec 16; 12(574): eaax3519. doi: 10.1126/scitranslmed.aax3519