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Select item 110079121.

A murine model for the del(GJB6-D13S1830) deletion recapitulating the phenotype of human DFNB1 hearing impairment: generation and functional and histopathological study

María Domínguez-Ruiz, Silvia Murillo-Cuesta, Julio Contreras, Marta Cantero, Gema Garrido, Belén Martín-Bernardo, Elena Gómez-Rosas, Almudena Fernández, Francisco J. del Castillo, Lluís Montoliu, Isabel Varela-Nieto, Ignacio del Castillo

BMC Genomics. 2024; 25: 359. Published online 2024 Apr 11. doi: 10.1186/s12864-024-10289-z

PMCID:: PMC11007912

Abstract Article PDF–2.6M

Select item 109572312.

The IgCAM BT-IgSF (IgSF11) Is Essential for Connexin43-Mediated Astrocyte–Astrocyte Coupling in Mice

Laura Pelz, Laura Dossou, Nine Kompier, René Jüttner, Gabrielle Siemonsmeier, Niklas Meyer, Elijah D. Lowenstein, Ines Lahmann, Helmut Kettenmann, Carmen Birchmeier, Fritz G. Rathjen

eNeuro. 2024 Mar; 11(3): ENEURO.0283-23.2024. Prepublished online 2024 Feb 22. Published online 2024 Mar 6. doi: 10.1523/ENEURO.0283-23.2024

PMCID:: PMC10957231

Abstract Article PDF–7.4M

Select item 102682403.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 100893554.

Upregulation of astroglial connexin 30 impairs hippocampal synaptic activity and recognition memory

Eléonore Hardy, Julien Moulard, Augustin Walter, Pascal Ezan, Alexis-Pierre Bemelmans, Franck Mouthon, Mathieu Charvériat, Nathalie Rouach, Armelle Rancillac

PLoS Biol. 2023 Apr; 21(4): e3002075. Published online 2023 Apr 11. doi: 10.1371/journal.pbio.3002075

PMCID:: PMC10089355

Abstract Article PDF–2.8M

Select item 97824895.

Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation

Yu Hashimoto, Ryo Yamasaki, Senri Ko, Eriko Matsuo, Yuko Kobayakawa, Katsuhisa Masaki, Dai Matsuse, Noriko Isobe

Int J Mol Sci. 2022 Dec; 23(24): 16046. Published online 2022 Dec 16. doi: 10.3390/ijms232416046

PMCID:: PMC9782489

Abstract Article PDF–3.7M

Select item 94819756.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 93956077.

Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss

Fabiola Paciello, Veronica Zorzi, Marcello Raspa, Ferdinando Scavizzi, Claudio Grassi, Fabio Mammano, Anna Rita Fetoni

Front Cell Dev Biol. 2022; 10: 950837. Published online 2022 Aug 9. doi: 10.3389/fcell.2022.950837

PMCID:: PMC9395607

Abstract Article PDF–2.3M

Select item 92567488.

Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification

Charles Petitpré, Louis Faure, Phoebe Uhl, Paula Fontanet, Iva Filova, Gabriela Pavlinkova, Igor Adameyko, Saida Hadjab, Francois Lallemend

Nat Commun. 2022; 13: 3878. Published online 2022 Jul 5. doi: 10.1038/s41467-022-31580-1

PMCID:: PMC9256748

Abstract Article PDF–3.9M

Select item 90911699.

Virally Mediated Connexin 26 Expression in Postnatal Scala Media Significantly and Transiently Preserves Hearing in Connexin 30 Null Mice

Li Zhang, Wenwen Wang, Sun Myoung Kim, Jianjun Wang, Binfei Zhou, Weijia Kong, James Zheng, Xi Lin

Front Cell Dev Biol. 2022; 10: 900416. Published online 2022 Apr 27. doi: 10.3389/fcell.2022.900416

Correction in:: Front Cell Dev Biol. 2022; 10: 969989.

PMCID:: PMC9091169

Abstract Article PDF–2.4M

Select item 835533710.

The developing mouse coronal suture at single-cell resolution

D’Juan T. Farmer, Hana Mlcochova, Yan Zhou, Nils Koelling, Guanlin Wang, Neil Ashley, Helena Bugacov, Hung-Jhen Chen, Riana Parvez, Kuo-Chang Tseng, Amy E. Merrill, Robert E. Maxson, Jr., Andrew O. M. Wilkie, J. Gage Crump, Stephen R. F. Twigg

Nat Commun. 2021; 12: 4797. Published online 2021 Aug 10. doi: 10.1038/s41467-021-24917-9

PMCID:: PMC8355337

Abstract Article PDF–9.6M

Select item 786839011.

miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis

Giulia Gentile, Fabiola Paciello, Veronica Zorzi, Antonio Gianmaria Spampinato, Maria Guarnaccia, Giulia Crispino, Abraham Tettey-Matey, Ferdinando Scavizzi, Marcello Raspa, Anna Rita Fetoni, Sebastiano Cavallaro, Fabio Mammano

Front Cell Dev Biol. 2020; 8: 616878. Published online 2021 Jan 25. doi: 10.3389/fcell.2020.616878

PMCID:: PMC7868390

Abstract Article PDF–5.4M

Select item 785970212.

Mutant Cx30-A88V mice exhibit hydrocephaly and sex-dependent behavioral abnormalities, implicating a functional role for Cx30 in the brain

Nicole M. Novielli-Kuntz, Eric R. Press, Kevin Barr, Marco A. M. Prado, Dale W. Laird

Dis Model Mech. 2021 Jan 1; 14(1): dmm046235. Published online 2021 Jan 26. doi: 10.1242/dmm.046235

PMCID:: PMC7859702

Abstract Article

Select item 737896013.

A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice

Yuanyuan Kuang, Veronica Zorzi, Damiano Buratto, Gaia Ziraldo, Flavia Mazzarda, Chiara Peres, Chiara Nardin, Anna Maria Salvatore, Francesco Chiani, Ferdinando Scavizzi, Marcello Raspa, Min Qiang, Youjun Chu, Xiaojie Shi, Yu Li, Lili Liu, Yaru Shi, Francesco Zonta, Guang Yang, Richard A. Lerner, Fabio Mammano

EBioMedicine. 2020 Jul; 57: 102825. Published online 2020 Jun 15. doi: 10.1016/j.ebiom.2020.102825

PMCID:: PMC7378960

Abstract Article PDF–3.5M

Select item 708617414.

Neuronal Activity Drives Astroglial Connexin 30 in Perisynaptic Processes and Shapes Its Functions

Grégory Ghézali, Flora Vasile, Nathan Curry, Marcus Fantham, Giselle Cheung, Pascal Ezan, Martine Cohen-Salmon, Clemens Kaminski, Nathalie Rouach

Cereb Cortex. 2020 Mar; 30(2): 753–766. Published online 2019 Jul 4. doi: 10.1093/cercor/bhz123

PMCID:: PMC7086174

Abstract Article PDF–1.4M

Select item 707249815.

Uncoupling of the Astrocyte Syncytium Differentially Affects AQP4 Isoforms

Shirin Katoozi, Nadia Skauli, Soulmaz Zahl, Tushar Deshpande, Pascal Ezan, Claudia Palazzo, Christian Steinhäuser, Antonio Frigeri, Martine Cohen-Salmon, Ole Petter Ottersen, Mahmood Amiry-Moghaddam

Cells. 2020 Feb; 9(2): 382. Published online 2020 Feb 7. doi: 10.3390/cells9020382

PMCID:: PMC7072498

Abstract Article PDF–1.7M

Select item 670491716.

Hearing Is Normal without Connexin30

Anne-Cécile Boulay, Francisco J. del Castillo, Fabrice Giraudet, Ghislaine Hamard, Christian Giaume, Christine Petit, Paul Avan, Martine Cohen-Salmon

J Neurosci. 2013 Jan 9; 33(2): 430–434. doi: 10.1523/JNEUROSCI.4240-12.2013

PMCID:: PMC6704917

Abstract Article PDF–476K

Select item 670357717.

Panglial Gap Junctional Communication is Essential for Maintenance of Myelin in the CNS

Oliver Tress, Marta Maglione, Dennis May, Tatjyana Pivneva, Nadine Richter, Julia Seyfarth, Sonja Binder, Armin Zlomuzica, Gerald Seifert, Martin Theis, Ekrem Dere, Helmut Kettenmann, Klaus Willecke

J Neurosci. 2012 May 30; 32(22): 7499–7518. doi: 10.1523/JNEUROSCI.0392-12.2012

PMCID:: PMC6703577

Abstract Article PDF–9.8M

Select item 667530018.

The Impact of Astrocytic Gap Junctional Coupling on Potassium Buffering in the Hippocampus

Anke Wallraff, Rüdiger Köhling, Uwe Heinemann, Martin Theis, Klaus Willecke, Christian Steinhäuser

J Neurosci. 2006 May 17; 26(20): 5438–5447. doi: 10.1523/JNEUROSCI.0037-06.2006

PMCID:: PMC6675300

Abstract Article PDF–1.3M

Select item 667035619.

A Central Role of Connexin 43 in Hypoxic Preconditioning

Jane H.-C. Lin, Nanhong Lou, Ning Kang, Takahiro Takano, Furong Hu, Xiaoning Han, Qiwu Xu, Ditte Lovatt, Arnulfo Torres, Klaus Willecke, Jay Yang, Jian Kang, Maiken Nedergaard

J Neurosci. 2008 Jan 16; 28(3): 681–695. doi: 10.1523/JNEUROSCI.3827-07.2008