PMC Links for GEO Profiles (Select 117250323) - PMC

Select item 93651201.

Sex-dimorphic gene effects on survival outcomes in people with coronary artery disease

Jennifer R. Dungan, Xue Qin, Simon G. Gregory, Rhonda Cooper-Dehoff, Julio D. Duarte, Huaizhen Qin, Martha Gulati, Jacquelyn Y. Taylor, Carl J. Pepine, Elizabeth R. Hauser, William E. Kraus

Am Heart J Plus. 2022 May; 17: 100152. Published online 2022 Jun 14. doi: 10.1016/j.ahjo.2022.100152

PMCID:: PMC9365120

Abstract Article PDF–3.4M

Select item 85535612.

Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice

Sumita Mishra, Nandhini Sadagopan, Brittany Dunkerly-Eyring, Susana Rodriguez, Dylan C. Sarver, Ryan P. Ceddia, Sean A. Murphy, Hildur Knutsdottir, Vivek P. Jani, Deepthi Ashok, Christian U. Oeing, Brian O’Rourke, Jon A. Gangoiti, Dorothy D. Sears, G. William Wong, Sheila Collins, David A. Kass

J Clin Invest. 2021 Nov 1; 131(21): e148798. Published online 2021 Nov 1. doi: 10.1172/JCI148798

PMCID:: PMC8553561

Abstract Article PDF–11M

Select item 84519723.

CRD-733, a novel phosphodiesterase 9 inhibitor, reverses pressure overload-induced heart failure

Daniel A. Richards, Mark J. Aronovitz, Peiwen Liu, Gregory L. Martin, Kelly Tam, Suchita Pande, Richard H. Karas, Daniel M. Bloomfield, Michael E. Mendelsohn, Robert M. Blanton

Circ Heart Fail. Author manuscript; available in PMC 2022 Jan 19.

Published in final edited form as: Circ Heart Fail. 2021 Jan; 14(1): e007300. Published online 2021 Jan 19. doi: 10.1161/CIRCHEARTFAILURE.120.007300

PMCID:: PMC8451972

Abstract Article PDF–4.3M

Select item 81203634.

Evaluation of phosphodiesterase 9A as a novel biomarker in heart failure with preserved ejection fraction

Christian Besler, Karl‐Philipp Rommel, Karl‐Patrik Kresoja, Justus Mörbitz, Holger Kirsten, Markus Scholz, Karin Klingel, Joachim Thiery, Ralph Burkhardt, Petra Büttner, Volker Adams, Holger Thiele, Philipp Lurz

ESC Heart Fail. 2021 Jun; 8(3): 1861–1872. Published online 2021 Mar 30. doi: 10.1002/ehf2.13327

PMCID:: PMC8120363

Abstract Article PDF–3.2M

Select item 55899685.

C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling

Pan-xia Wang, Zhuo-ming Li, Si-dong Cai, Jing-yan Li, Ping He, Yi Huang, Guo-shuai Feng, Hai-bin Luo, Shao-rui Chen, Pei-qing Liu

Acta Pharmacol Sin. 2017 Sep; 38(9): 1257–1268. Published online 2017 Jun 26. doi: 10.1038/aps.2017.38

PMCID:: PMC5589968

Abstract Article PDF–2.8M

Select item 48821906.

Widespread expansion of protein interaction capabilities by alternative splicing

Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal

Cell. Author manuscript; available in PMC 2017 Feb 11.

Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029

PMCID:: PMC4882190

Abstract Article PDF–1.9M

Select item 43766097.

Phosphodiesterase 9A Controls Nitric-oxide Independent cGMP and Hypertrophic Heart Disease

Dong I. Lee, Guangshuo Zhu, Takashi Sasaki, Gun-Sik Cho, Nazha Hamdani, Ronald Holewinski, Su-Hyun Jo, Thomas Danner, Manling Zhang, Peter P. Rainer, Djahida Bedja, Jonathan A. Kirk, Mark J. Ranek, Wolfgang R. Dostmann, Chulan Kwon, Kenneth B. Margulies, Jennifer E. Van Eyk, Walter J. Paulus, Eiki Takimoto, David A. Kass

Nature. Author manuscript; available in PMC 2015 Sep 26.

Published in final edited form as: Nature. 2015 Mar 26; 519(7544): 472–476. Published online 2015 Mar 18. doi: 10.1038/nature14332

PMCID:: PMC4376609

Abstract Article PDF–2.6M

Select item 34669698.

Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice

Camila Bononi Almeida, Christoph Scheiermann, Jung-Eun Jang, Colette Prophete, Fernando Ferreira Costa, Nicola Conran, Paul S. Frenette

Blood. 2012 Oct 4; 120(14): 2879–2888. Prepublished online 2012 Jul 25. doi: 10.1182/blood-2012-02-409524

PMCID:: PMC3466969

Abstract Article

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 152672810.

Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins

Yu-Hui Hu, Hans-Jörg Warnatz, Dominique Vanhecke, Florian Wagner, Andrea Fiebitz, Sabine Thamm, Pascal Kahlem, Hans Lehrach, Marie-Laure Yaspo, Michal Janitz

BMC Genomics. 2006; 7: 155. Published online 2006 Jun 16. doi: 10.1186/1471-2164-7-155

PMCID:: PMC1526728

Abstract Article PDF–8.1M

Select item 13924111.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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