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Select item 105720101.

Unveiling Neuroprotection and Regeneration Mechanisms in Optic Nerve Injury: Insight from Neural Progenitor Cell Therapy with Focus on Vps35 and Syntaxin12

Hyun-Ah Shin, Mira Park, Hey Jin Lee, Van-An Duong, Hyun-Mun Kim, Dong-Youn Hwang, Hookeun Lee, Helen Lew

Cells. 2023 Oct; 12(19): 2412. Published online 2023 Oct 6. doi: 10.3390/cells12192412

PMCID:: PMC10572010

Abstract Article PDF–5.0M

Select item 104038582.

VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson’s disease

Xi Chen, Elpida Tsika, Nathan Levine, Darren J. Moore

Mol Neurodegener. 2023; 18: 51. Published online 2023 Aug 4. doi: 10.1186/s13024-023-00641-4

PMCID:: PMC10403858

Abstract Article PDF–14M

Select item 76115563.

Wingless Secretion requires endosome-to-Golgi retrival of Wntless/Evi/Sprinter by the retromer complex

Xavier Franch-Marro, Franz Wendler, Sonia Guidato, Janice Griffith, Alberto Baena-Lopez, Nobue Itasaki, Madelon M. Maurice, Jean-Paul Vincent

Nat Cell Biol. Author manuscript; available in PMC 2021 Aug 23.

Published in final edited form as: Nat Cell Biol. 2008 Feb 1; 10(2): 170–7. Published online 2008 Jan 13. doi: 10.1038/ncb1678

PMCID:: PMC7611556

Abstract Article PDF–2.2M

Select item 65968314.

Cellular Functions of the Autism Risk Factor PTCHD1 in Mice

David Tora, Andrea M. Gomez, Jean-Francois Michaud, Patricia T. Yam, Frédéric Charron, Peter Scheiffele

J Neurosci. 2017 Dec 6; 37(49): 11993–12005. doi: 10.1523/JNEUROSCI.1393-17.2017

PMCID:: PMC6596831

Abstract Article PDF–4.9M

Select item 58342285.

Genes associated with Parkinson’s disease: regulation of autophagy and beyond

Alexandra Beilina, Mark R Cookson

J Neurochem. Author manuscript; available in PMC 2018 Mar 2.

Published in final edited form as: J Neurochem. 2016 Oct; 139(Suppl 1): 91–107. Published online 2015 Sep 3. doi: 10.1111/jnc.13266

PMCID:: PMC5834228

Abstract Article PDF–1018K

Select item 58129986.

VPS35 depletion does not impair presynaptic structure and function

Sonia Vazquez-Sanchez, Sander Bobeldijk, Marien P. Dekker, Linda van Keimpema, Jan R. T. van Weering

Sci Rep. 2018; 8: 2996. Published online 2018 Feb 14. doi: 10.1038/s41598-018-20448-4

PMCID:: PMC5812998

Abstract Article PDF–7.0M

Select item 57901137.

Retriever, a multiprotein complex for retromer-independent endosomal cargo recycling

Kerrie E. McNally, Rebecca Faulkner, Florian Steinberg, Matthew Gallon, Rajesh Ghai, David Pim, Paul Langton, Neil Pearson, Chris M. Danson, Heike Nägele, Lindsey M Morris, Arnika Singla, Brittany L Overlee, Kate J. Heesom, Richard Sessions, Lawrence Banks, Brett M Collins, Imre Berger, Daniel D. Billadeau, Ezra Burstein, Peter J. Cullen

Nat Cell Biol. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Nat Cell Biol. 2017 Oct; 19(10): 1214–1225. Published online 2017 Sep 11. doi: 10.1038/ncb3610

PMCID:: PMC5790113

Abstract Article PDF–1.6M

Select item 50184328.

VPS35 regulates cell surface recycling and signaling of dopamine receptor D1

Chen Wang, Mengxi Niu, Zehua Zhou, Xiaoyuan Zheng, Lingzhi Zhang, Ye Tian, Xiaojun Yu, Guojun Bu, Huaxi Xu, Qilin Ma, Yun-wu Zhang

Neurobiol Aging. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Neurobiol Aging. 2016 Oct; 46: 22–31. Published online 2016 May 21. doi: 10.1016/j.neurobiolaging.2016.05.016

PMCID:: PMC5018432

Abstract Article PDF–1.5M

Select item 50000769.

Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation

Jordan Follett, Andrea Bugarcic, Zhe Yang, Nicholas Ariotti, Suzanne J. Norwood, Brett M. Collins, Robert G. Parton, Rohan D. Teasdale

J Biol Chem. 2016 Aug 26; 291(35): 18283–18298. Published online 2016 Jul 6. doi: 10.1074/jbc.M115.703157

PMCID:: PMC5000076

Abstract Article PDF–5.8M

Select item 482661110.

Parkinson’s disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

Wenzhang Wang, Xinglong Wang, Hisashi Fujioka, Charles Hoppel, Alan L. Whone, Maeve A. Caldwell, Peter J. Cullen, Jun Liu, Xiongwei Zhu

Nat Med. Author manuscript; available in PMC 2016 May 30.

Published in final edited form as: Nat Med. 2016 Jan; 22(1): 54–63. Published online 2015 Nov 30. doi: 10.1038/nm.3983

PMCID:: PMC4826611

Abstract Article PDF–3.1M

Select item 479296311.

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Paulina Bartuzi, Daniel D. Billadeau, Robert Favier, Shunxing Rong, Daphne Dekker, Alina Fedoseienko, Hille Fieten, Melinde Wijers, Johannes H. Levels, Nicolette Huijkman, Niels Kloosterhuis, Henk van der Molen, Gemma Brufau, Albert K. Groen, Alison M. Elliott, Jan Albert Kuivenhoven, Barbara Plecko, Gernot Grangl, Julie McGaughran, Jay D. Horton, Ezra Burstein, Marten H. Hofker, Bart van de Sluis

Nat Commun. 2016; 7: 10961. Published online 2016 Mar 11. doi: 10.1038/ncomms10961

PMCID:: PMC4792963

Abstract Article PDF–2.4M

Select item 474056512.

Impaired intracellular trafficking defines early Parkinson's disease

Benjamin H.M. Hunn, Stephanie J. Cragg, J. Paul Bolam, Maria-Grazia Spillantini, Richard Wade-Martins

Trends Neurosci. 2015 Mar; 38(3): 178–188. doi: 10.1016/j.tins.2014.12.009

PMCID:: PMC4740565

Abstract Article

Select item 462824713.

VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation

Yun Tian, Fu-Lei Tang, XiangDong Sun, Lei Wen, Lin Mei, Bei-Sha Tang, Wen-Cheng Xiong

Mol Brain. 2015; 8: 70. Published online 2015 Oct 31. doi: 10.1186/s13041-015-0156-4

PMCID:: PMC4628247

Abstract Article PDF–1.8M

Select item 451029614.

VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for α-Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease

Fu-Lei Tang, Joanna R. Erion, Yun Tian, Wei Liu, Dong-Min Yin, Jian Ye, Baisha Tang, Lin Mei, Wen-Cheng Xiong

J Neurosci. 2015 Jul 22; 35(29): 10613–10628. doi: 10.1523/JNEUROSCI.0042-15.2015

PMCID:: PMC4510296

Abstract Article PDF–10M

Select item 428908115.

Parkinson’s disease genes VPS35 and EIF4G1 interact genetically and converge on α–synuclein

Nripesh Dhungel, Simona Eleuteri, Ling-bo Li, Nicholas J. Kramer, Justin Chartron, Brian Spencer, Kori Kosberg, Jerel Adam Fields, Stafa Klodjan, Anthony Adame, Hilal Lashuel, Judith Frydman, Kang Shen, Eliezer Masliah, Aaron D. Gitler

Neuron. Author manuscript; available in PMC 2016 Jan 7.

Published in final edited form as: Neuron. 2015 Jan 7; 85(1): 76–87. Published online 2014 Dec 18. doi: 10.1016/j.neuron.2014.11.027