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Items: 1 to 20 of 32

1.
Immunotherapy targeting isoDGR‐protein damage extends lifespan in a mouse model of protein deamidation
Pazhanichamy Kalailingam, Khalilatul‐Hanisah Mohd‐Kahliab, SoFong Cam Ngan, Ranjith Iyappan, Evelin Melekh, Tian Lu, Gan Wei Zien, Bhargy Sharma, Tiannan Guo, Adam J MacNeil, Rebecca EK MacPherson, Evangelia Litsa Tsiani, Deborah D O'Leary, Kah Leong Lim, I Hsin Su, Yong‐Gui Gao, A Mark Richards, Raj N Kalaria, Christopher P Chen, Neil E McCarthy, Siu Kwan Sze
EMBO Mol Med. 2023 Dec; 15(12): e18526. Published online 2023 Nov 16. doi: 10.15252/emmm.202318526
PMCID:
PMC10701600
AbstractArticlePDF–13M
2.
PIMT is a novel and potent suppressor of endothelial activation
Chen Zhang, Zhi-Fu Guo, Wennan Liu, Kyosuke Kazama, Louis Hu, Xiaobo Sun, Lu Wang, Hyoungjoo Lee, Lin Lu, Xiao-Feng Yang, Ross Summer, Jianxin Sun
eLife. 2023; 12: e85754. Published online 2023 Apr 18. doi: 10.7554/eLife.85754
PMCID:
PMC10112892
AbstractArticlePDF–8.7M
3.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
4.
Deficiency in Protein l-Isoaspartyl Methyltransferase Results in a Fatal Progressive Epilepsy
Akihiro Yamamoto, Hideyuki Takagi, Daisuke Kitamura, Hozumi Tatsuoka, Hirotake Nakano, Hitoshi Kawano, Hidehito Kuroyanagi, Yu-ichi Yahagi, Shin-ichiro Kobayashi, Ken-ichi Koizumi, Tsuyoshi Sakai, Ken-ichi Saito, Tanemichi Chiba, Koki Kawamura, Katsushi Suzuki, Takeshi Watanabe, Hiroshi Mori, Takuji Shirasawa
J Neurosci. 1998 Mar 15; 18(6): 2063–2074. doi: 10.1523/JNEUROSCI.18-06-02063.1998
Correction in:
J Neurosci. 1998 Jun 15; 18(12): np.
PMCID:
PMC6792936
AbstractArticlePDF–934K
5.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
6.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner
Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler
J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.
Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027
PMCID:
PMC6554723
AbstractArticlePDF–2.0M
7.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
8.
Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity
Tara Vanderweyde, Daniel J. Apicco, Katherine Youmans-Kidder, Peter E.A. Ash, Casey Cook, Edroaldo Lummertz da Rocha, Karen Jansen-West, Alissa A. Frame, Allison Citro, John D. Leszyk, Pavel Ivanov, Jose F. Abisambra, Martin Steffen, Hu Li, Leonard Petrucelli, Benjamin Wolozin
Cell Rep. Author manuscript; available in PMC 2017 Feb 24.
Published in final edited form as: Cell Rep. 2016 May 17; 15(7): 1455–1466. Published online 2016 May 6. doi: 10.1016/j.celrep.2016.04.045
PMCID:
PMC5325702
AbstractArticlePDF–2.1M
9.
Accelerated protein damage in brains of PIMT +/− mice; a possible model for the variability of cognitive decline in human aging
Qin Zhenxia, Dimitrijevic Aleksandra, Aswad Dana W.
Neurobiol Aging. Author manuscript; available in PMC 2016 Feb 1.
Published in final edited form as: Neurobiol Aging. 2015 Feb; 36(2): 1029–1036. Published online 2014 Nov 4. doi: 10.1016/j.neurobiolaging.2014.10.036
PMCID:
PMC4315693
AbstractArticlePDF–740K
10.
Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse
Aleksandra Dimitrijevic, Zhenxia Qin, Dana W. Aswad
PLoS One. 2014; 9(6): e100622. Published online 2014 Jun 23. doi: 10.1371/journal.pone.0100622
Correction in:
PLoS One. 2014; 9(12): e116556.
PMCID:
PMC4067349
AbstractArticlePDF–2.8M
11.
Isoaspartyl Protein Damage and Repair in Mouse Retina
Zhenxia Qin, Jing Yang, Henry J. Klassen, Dana W. Aswad
Invest Ophthalmol Vis Sci. 2014 Mar; 55(3): 1572–1579. Published online 2014 Mar 13. doi: 10.1167/iovs.13-13668
PMCID:
PMC3954159
AbstractArticlePDF–575K
12.
ERK2-Mediated Phosphorylation of Transcriptional Coactivator Binding Protein PIMT/NCoA6IP at Ser298 Augments Hepatic Gluconeogenesis
Bandish Kapadia, Navin Viswakarma, Kishore V. L. Parsa, Vasundhara Kain, Soma Behera, Sashidhara Kaimal Suraj, Phanithi Prakash Babu, Anand Kar, Sunanda Panda, Yi-jun Zhu, Yuzhi Jia, Bayar Thimmapaya, Janardan K. Reddy, Parimal Misra
PLoS One. 2013; 8(12): e83787. Published online 2013 Dec 17. doi: 10.1371/journal.pone.0083787
PMCID:
PMC3866170
AbstractArticlePDF–2.1M
13.
Brain proteomics supports the role of glutamate metabolism and suggests other metabolic alterations in protein L-isoaspartyl methyltransferase (PIMT)-knockout mice
Hongqian Yang, Jonathan D. Lowenson, Steven Clarke, Roman A. Zubarev
J Proteome Res. Author manuscript; available in PMC 2014 Oct 4.
Published in final edited form as: J Proteome Res. 2013 Oct 4; 12(10): 10.1021/pr400688r. Published online 2013 Sep 10. doi: 10.1021/pr400688r
PMCID:
PMC3818641
AbstractArticlePDF–1.1M
14.
Isoaspartate Accumulation in Mouse Brain Is Associated with Altered Patterns of Protein Phosphorylation and Acetylation, Some of Which Are Highly Sex-Dependent
Zhenxia Qin, Rachel S. Kaufman, Rana N. Khoury, Mitri K. Khoury, Dana W. Aswad
PLoS One. 2013; 8(11): e80758. Published online 2013 Nov 5. doi: 10.1371/journal.pone.0080758
PMCID:
PMC3818261
AbstractArticlePDF–1.1M
15.
Autoimmunity to isomerized histone H2B in systemic lupus erythematosus
HESTER A. DOYLE, DANA W. ASWAD, MARK J. MAMULA
Autoimmunity. Author manuscript; available in PMC 2013 Feb 1.
Published in final edited form as: Autoimmunity. 2013 Feb; 46(1): 6–13. Published online 2012 Dec 3. doi: 10.3109/08916934.2012.710859
PMCID:
PMC3543506
AbstractArticlePDF–460K
16.
Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1−/− Mice
Kennen B. MacKay, Jonathan D. Lowenson, Steven G. Clarke
PLoS One. 2012; 7(10): e46719. Published online 2012 Oct 5. doi: 10.1371/journal.pone.0046719
PMCID:
PMC3465263
AbstractArticlePDF–4.3M
17.
Considerations in the Identification of Endogenous Substrates for Protein L-Isoaspartyl Methyltransferase: The Case of Synuclein
Gareth J. Morrison, Ranjani Ganesan, Zhenxia Qin, Dana W. Aswad
PLoS One. 2012; 7(8): e43288. Published online 2012 Aug 14. doi: 10.1371/journal.pone.0043288
PMCID:
PMC3419188
AbstractArticlePDF–1.3M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins
James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters
Science. Author manuscript; available in PMC 2010 Nov 22.
Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348
PMCID:
PMC2989461
AbstractArticlePDF–2.2M

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