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Items: 1 to 20 of 85

1.
Listeria adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for Listeria monocytogenes translocation
Rishi Drolia, Donald B. Bryant, Shivendra Tenguria, Zuri A. Jules-Culver, Jessie Thind, Breanna Amelunke, Dongqi Liu, Nicholas L. F. Gallina, Krishna K. Mishra, Manalee Samaddar, Manoj R. Sawale, Dharmendra K. Mishra, Abigail D. Cox, Arun K. Bhunia
mBio. 2024 Mar; 15(3): e02821-23. Published online 2024 Feb 20. doi: 10.1128/mbio.02821-23
PMCID:
PMC10936185
AbstractArticlePDF–10M
2.
IGF2BP3-mediated enhanced stability of MYLK represses MSC adipogenesis and alleviates obesity and insulin resistance in HFD mice
Xiuji Huang, Wuhui He, Shuai Fan, Hui Li, Guiwen Ye
Cell Mol Life Sci. 2024 Dec; 81(1): 17. Published online 2024 Jan 10. doi: 10.1007/s00018-023-05076-0
PMCID:
PMC10776757
AbstractArticlePDF–8.7M
3.
p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle
Jaspreet Kalra, Mykhaylo Artamonov, Hua Wang, Aaron Franke, Zaneta Markowska, Li Jin, Zygmunt S. Derewenda, Ramon J. Ayon, Avril Somlyo
Front Physiol. 2023; 14: 1228488. Published online 2023 Sep 13. doi: 10.3389/fphys.2023.1228488
PMCID:
PMC10533999
AbstractArticlePDF–2.8M
4.
Myosin light chain kinase deletion worsens lung permeability and increases mortality in pneumonia-induced sepsis
Deena B. Chihade, Prestina Smith, David A. Swift, Shunsuke Otani, Wenxiao Zhang, Ching-Wen Chen, Lauren A. Jeffers, Zhe Liang, Takashi Shimazui, Eileen M. Burd, Alton B. Farris, Bashar S. Staitieh, David M. Guidot, Mandy L. Ford, Michael Koval, Craig M. Coopersmith
Shock. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: Shock. 2023 Apr 1; 59(4): 612–620. Published online 2023 Jan 14. doi: 10.1097/SHK.0000000000002081
PMCID:
PMC10065930
AbstractArticlePDF–1.6M
5.
The tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease
Li Zuo, Wei-Ting Kuo, Feng Cao, Sandra D. Chanez-Paredes, Daniel Zeve, Prabhath Mannam, Léa Jean-François, Anne Day, W Vallen Graham, Yan Y. Sweat, Nitesh Shashikanth, David T. Breault, Jerrold R. Turner
Gut. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: Gut. 2023 May; 72(5): 870–881. Published online 2022 May 10. doi: 10.1136/gutjnl-2021-326534
PMCID:
PMC9977574
AbstractArticlePDF–5.2M
6.
PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation
Michael C. Schmid, Sang Won Kang, Hui Chen, Marc Paradise, Anghesom Ghebremedhin, Megan M. Kaneda, Shao-Ming Chin, Anh Do, D. Martin Watterson, Judith A. Varner
Nat Commun. 2022; 13: 1768. Published online 2022 Apr 1. doi: 10.1038/s41467-022-29471-6
PMCID:
PMC8975949
AbstractArticlePDF–2.6M
7.
Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function
Vaishali N. Patel, Dallas L. Pineda, Elsa Berenstein, Belinda R. Hauser, Sophie Choi, Michaela Prochazkova, Changyu Zheng, Corinne M. Goldsmith, Toin H. van Kuppevelt, Ashok Kulkarni, Yuefan Song, Robert J. Linhardt, Alejandro M. Chibly, Matthew P. Hoffman
Matrix Biol. Author manuscript; available in PMC 2022 Oct 12.
Published in final edited form as: Matrix Biol. 2021 Sep; 103-104: 37–57. Published online 2021 Oct 12. doi: 10.1016/j.matbio.2021.10.002
PMCID:
PMC8629026
AbstractArticlePDF–2.7M
8.
A novel tumor suppressor role of myosin light chain kinase splice variants through downregulation of the TEAD4/CD44 axis
Yen-Ju Huang, Tsung-Chun Lee, Yu-Chen Pai, Been-Ren Lin, Jerrold R Turner, Linda Chia-Hui Yu
Carcinogenesis. 2021 Jul; 42(7): 961–974. Published online 2021 May 17. doi: 10.1093/carcin/bgab038
PMCID:
PMC8283729
AbstractArticlePDF–35M
9.
Smooth Muscle Differentiation is Essential for Airway Size, Tracheal Cartilage Segmentation, but Dispensable for Epithelial Branching
Randee E. Young, Mary-Kayt Jones, Elizabeth A. Hines, Rongbo Li, Yongfeng Luo, Wei Shi, Jamie M. Verheyden, Xin Sun
Dev Cell. Author manuscript; available in PMC 2021 Apr 6.
Published in final edited form as: Dev Cell. 2020 Apr 6; 53(1): 73–85.e5. Published online 2020 Mar 5. doi: 10.1016/j.devcel.2020.02.001
PMCID:
PMC7540204
AbstractArticlePDF–2.9M
10.
Noncanonical function of long myosin light chain kinase in increasing ER‐PM junctions and augmentation of SOCE
Nityanand Srivastava, Mohammad Tauseef, Ruhul Amin, Bhagwati Joshi, Jagdish Chandra Joshi, Vidisha Kini, Jennifer Klomp, Weenan Li, Nebojsa Knezevic, Nicolas Barbera, Shahid Siddiqui, Alexander Obukhov, Andrei Karginov, Irena Levitan, Yulia Komarova, Dolly Mehta
FASEB J. 2020 Sep; 34(9): 12805–12819. Published online 2020 Aug 9. doi: 10.1096/fj.201902462RR
PMCID:
PMC7496663
AbstractArticlePDF–1.5M
11.
Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface
Rongbo Li, Xiaoping Li, James Hagood, Min-Sheng Zhu, Xin Sun
J Clin Invest. 2020 Jun 1; 130(6): e132189. Published online 2020 Apr 27. doi: 10.1172/JCI132189
PMCID:
PMC7260039
AbstractArticlePDF–29M
12.
CRISPR-Cas9/phosphoproteomics identifies multiple noncanonical targets of myosin light chain kinase
Kiyoshi Isobe, Viswanathan Raghuram, Laya Krishnan, Chung-Lin Chou, Chin-Rang Yang, Mark A. Knepper
Am J Physiol Renal Physiol. 2020 Mar 1; 318(3): F600–F616. Published online 2020 Jan 6. doi: 10.1152/ajprenal.00431.2019
PMCID:
PMC7099502
AbstractArticle
13.
Loss-of-function variants in myocardin cause congenital megabladder in humans and mice
Arjan C. Houweling, Glenda M. Beaman, Alex V. Postma, T. Blair Gainous, Klaske D. Lichtenbelt, Francesco Brancati, Filipa M. Lopes, Ingeborg van der Made, Abeltje M. Polstra, Michael L. Robinson, Kevin D. Wright, Jamie M. Ellingford, Ashley R. Jackson, Eline Overwater, Rita Genesio, Silvio Romano, Letizia Camerota, Emanuela D’Angelo, Elizabeth J. Meijers-Heijboer, Vincent M. Christoffels, Kirk M. McHugh, Brian L. Black, William G. Newman, Adrian S. Woolf, Esther E. Creemers
J Clin Invest. 2019 Dec 2; 129(12): 5374–5380. Published online 2019 Nov 4. doi: 10.1172/JCI128545
PMCID:
PMC6877301
AbstractArticlePDF–8.0M
14.
Adamts5−/− Mice Exhibit Altered Aggrecan Proteolytic Profiles That Correlate with Ascending Aortic Anomalies
Loren E. Dupuis, E. Lockett Nelson, Brittany Hozik, Sarah C. Porto, Alexandra Rogers-DeCotes, Amanda Fosang, Christine B. Kern
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Oct; 39(10): 2067–2081. Published online 2019 Aug 1. doi: 10.1161/ATVBAHA.119.313077
PMCID:
PMC6761016
AbstractArticlePDF–8.0M
15.
Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
Rishi Drolia, Shivendra Tenguria, Abigail C. Durkes, Jerrold R. Turner, Arun K. Bhunia
Cell Host Microbe. Author manuscript; available in PMC 2019 Sep 18.
Published in final edited form as: Cell Host Microbe. 2018 Apr 11; 23(4): 470–484.e7. Published online 2018 Apr 5. doi: 10.1016/j.chom.2018.03.004
PMCID:
PMC6750208
AbstractArticlePDF–2.0M
16.
Secretory pathway calcium ATPase 1 (SPCA1) controls mouse neural tube closure by regulating cytoskeletal dynamics
Joel M. Brown, María J. García-García
Development. 2018 Oct 1; 145(19): dev170019. Published online 2018 Oct 5. doi: 10.1242/dev.170019
PMCID:
PMC6514415
AbstractArticle
17.
Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis
W Vallen Graham, Weiqi He, Amanda M. Marchiando, Juanmin Zha, Gurminder Singh, Hua-Shan Li, Amlan Biswas, Ma. Lora Drizella M. Ong, Zhi-Hui Jiang, Wangsun Choi, Harmon Zuccola, Yitang Wang, James Griffith, Jingshing Wu, Harry J. Rosenberg, Yingmin Wang, Scott B. Snapper, David Ostrov, Stephen C. Meredith, Lawrence W. Miller, Jerrold R. Turner
Nat Med. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Nat Med. 2019 Apr; 25(4): 690–700. Published online 2019 Apr 1. doi: 10.1038/s41591-019-0393-7
PMCID:
PMC6461392
AbstractArticlePDF–1.9M
18.
MMP-9-induced increase in intestinal epithelial tight permeability is mediated by p38 kinase signaling pathway activation of MLCK gene
Rana Al-Sadi, Moustafa Youssef, Manmeet Rawat, Shuhong Guo, Karol Dokladny, Mohammad Haque, Martin D. Watterson, Thomas Y. Ma
Am J Physiol Gastrointest Liver Physiol. 2019 Feb 1; 316(2): G278–G290. Published online 2018 Dec 13. doi: 10.1152/ajpgi.00126.2018
PMCID:
PMC6397336
AbstractArticle
19.
Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability
Sam C. Nalle, Li Zuo, Ma. Lora Drizella M. Ong, Gurminder Singh, Alicia M. Worthylake, Wangsun Choi, Mario Cabrero Manresa, Anna P. Southworth, Karen L. Edelblum, Gregory J. Baker, Nora E. Joseph, Peter A. Savage, Jerrold R. Turner
J Clin Invest. 2019 Feb 1; 129(2): 902–914. Published online 2019 Jan 22. doi: 10.1172/JCI98554
PMCID:
PMC6355225
AbstractArticlePDF–25M
20.
The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene
Joseph B. Mascarenhas, Alex Y. Tchourbanov, Sergei M. Danilov, Tong Zhou, Ting Wang, Joe G. N. Garcia
Am J Respir Cell Mol Biol. 2018 May; 58(5): 604–613. doi: 10.1165/rcmb.2017-0141OC
PMCID:
PMC5946327
AbstractArticlePDF–976K

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