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Items: 1 to 20 of 129

1.
SLMAP3 is essential for neurulation through mechanisms involving cytoskeletal elements, ABP, and PCP
Taha Rehmani, Ana Paula Dias, Billi Dawn Applin, Maysoon Salih, Balwant S Tuana
Life Sci Alliance. 2024 Dec; 7(12): e202302545. Published online 2024 Oct 4. doi: 10.26508/lsa.202302545
PMCID:
PMC11452652
AbstractArticlePDF–3.7M
2.
The PP2A regulator IER5L supports prostate cancer progression
Jana R. Crespo, Natalia Martín-Martín, Saioa Garcia-Longarte, Jon Corres-Mendizabal, Onintza Carlevaris, Ianire Astobiza, Amaia Zabala-Letona, Marc Guiu, Mikel Azkargorta, Monika Gonzalez-Lopez, Nuria Macías-Cámara, Phuong Doan, Félix Elortza, Isabel Mendizabal, Jukka Westermack, Roger R. Gomis, Amaia Ercilla, Arkaitz Carracedo
Cell Death Dis. 2024 Jul; 15(7): 514. Published online 2024 Jul 18. doi: 10.1038/s41419-024-06907-z
PMCID:
PMC11258296
AbstractArticlePDF–2.6M
3.
Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway
Taha Rehmani, Ana Paula Dias, Marsel Kamal, Maysoon Salih, Balwant S. Tuana
Int J Mol Sci. 2024 Mar; 25(5): 2888. Published online 2024 Mar 1. doi: 10.3390/ijms25052888
PMCID:
PMC10932035
AbstractArticlePDF–4.4M
4.
Protein phosphatase 2A propels follicular T helper cell development in lupus
Yu Jiang, Xuexiao Jin, Zhexu Chi, Yadan Bai, Kalpana Manthiram, Pamela Mudd, Kaixiang Zhu, Lie Wang, Pamela L. Schwartzberg, Yongmei Han, Xiang Gao, Linrong Lu, Qin Xu
J Autoimmun. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: J Autoimmun. 2023 Apr; 136: 103028. Published online 2023 Mar 29. doi: 10.1016/j.jaut.2023.103028
PMCID:
PMC10327577
AbstractArticlePDF–2.6M
5.
The MASTL/PP2A cell cycle kinase‐phosphatase module restrains PI3K‐Akt activity in an mTORC1‐dependent manner
Belén Sanz‐Castillo, Begoña Hurtado, Diana Vara‐Ciruelos, Aicha El Bakkali, Dario Hermida, Beatriz Salvador‐Barbero, Diego Martínez‐Alonso, José González‐Martínez, Clara Santiveri, Ramón Campos‐Olivas, Pilar Ximénez‐Embún, Javier Muñoz, Mónica Álvarez‐Fernández, Marcos Malumbres
EMBO J. 2023 Jan; 42(2): e110833. Published online 2022 Nov 10. doi: 10.15252/embj.2022110833
PMCID:
PMC9841333
AbstractArticlePDF–2.7M
6.
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response
Amrita Sule, Sarah E. Golding, Syed F. Ahmad, James Watson, Mostafa H. Ahmed, Glen E. Kellogg, Tytus Bernas, Sean Koebley, Jason C. Reed, Lawrence F. Povirk, Kristoffer Valerie
Cell Mol Life Sci. 2022; 79(12): 603. Published online 2022 Nov 24. doi: 10.1007/s00018-022-04550-5
PMCID:
PMC9700600
AbstractArticlePDF–3.6M
7.
Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury
Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, Jing Wu, Qi Cheng, Hua-Jian Teng, Di Chen, Xiang Lu, Chao-Jun Li, Qing Jiang, Lei Fang, Bin Xue
Cell Death Dis. 2022 Nov; 13(11): 985. Published online 2022 Nov 22. doi: 10.1038/s41419-022-05353-z
PMCID:
PMC9684557
AbstractArticlePDF–8.0M
8.
Liver PP2A-Cα Protects From Parenteral Nutrition-associated Hepatic Steatosis
Gulisudumu Maitiabula, Feng Tian, Peng Wang, Li Zhang, Xuejin Gao, Songlin Wan, Haifeng Sun, Jianbo Yang, Yupeng Zhang, Tingting Gao, Bin Xue, Chaojun Li, Jieshou Li, Xinying Wang
Cell Mol Gastroenterol Hepatol. 2022; 14(3): 669–692. Published online 2022 May 26. doi: 10.1016/j.jcmgh.2022.05.008
PMCID:
PMC9421584
AbstractArticlePDF–8.4M
9.
Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis
Ulrich Gergs, Tina Jahn, Nico Schulz, Claudia Großmann, Uwe Rueckschloss, Uta Demus, Igor B. Buchwalow, Joachim Neumann
Int J Mol Sci. 2022 May; 23(9): 4688. Published online 2022 Apr 23. doi: 10.3390/ijms23094688
PMCID:
PMC9101092
AbstractArticlePDF–4.3M
10.
Overexpression of Heat Shock Protein 70 Improves Cardiac Remodeling and Survival in Protein Phosphatase 2A-Expressing Transgenic Mice with Chronic Heart Failure
Somy Yoon, Ulrich Gergs, Julie R. McMullen, Gwang Hyeon Eom
Cells. 2021 Nov; 10(11): 3180. Published online 2021 Nov 15. doi: 10.3390/cells10113180
PMCID:
PMC8624068
AbstractArticlePDF–2.2M
11.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin, Elisa Barbieri, Deborah A. Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J. Kearney, Jarrod J. Sandow, Zheng Fan, Benjamin Blyth, Victoria McLeod, Joseph H.A. Vissers, Karolina Pavic, Ben P. Martin, Gareth Gregory, Elena Demosthenous, Magnus Zethoven, Isabella Y. Kong, Edwin D. Hawkins, Simon J. Hogg, Madison J. Kelly, Andrea Newbold, Kaylene J. Simpson, Otto Kauko, Kieran F. Harvey, Michael Ohlmeyer, Jukka Westermarck, Nathanael Gray, Alessandro Gardini, Ricky W. Johnstone
Cell. Author manuscript; available in PMC 2022 Jun 10.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3143–3162.e32. Published online 2021 May 17. doi: 10.1016/j.cell.2021.04.022
PMCID:
PMC8567840
AbstractArticlePDF–2.8M
12.
Protein Phosphatase 2A Activation via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome
Haiyan Chu, Anastasia Sacharidou, An Nguyen, Chun Li, Ken L. Chambliss, Jane E. Salmon, Yu-Min Shen, Julie Lo, Gustavo W. Leone, Joachim Herz, David Y. Hui, Denise K. Marciano, Vikki M. Abrahams, Bryony V. Natale, Alina P. Montalbano, Xue Xiao, Lin Xu, David R. Natale, Philip W. Shaul, Chieko Mineo
Circ Res. Author manuscript; available in PMC 2022 Sep 17.
Published in final edited form as: Circ Res. 2021 Sep 17; 129(7): 735–750. Published online 2021 Aug 18. doi: 10.1161/CIRCRESAHA.120.318941
PMCID:
PMC8448973
AbstractArticlePDF–2.6M
13.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
14.
Tumor‐associated macrophages promote the metastasis and growth of non‐small‐cell lung cancer cells through NF‐κB/PP2Ac‐positive feedback loop
Zhan‐Wen Liang, Xin‐Xin Ge, Meng‐Dan Xu, Hualong Qin, Meng‐Yao Wu, Meng Shen, Yan Zhang, Xiao‐Meng Liu, Kai Chen, Wei Li, Weiming Duan, Songbing Qin
Cancer Sci. 2021 Jun; 112(6): 2140–2157. Published online 2021 May 1. doi: 10.1111/cas.14863
PMCID:
PMC8177805
AbstractArticlePDF–3.7M
15.
PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation
Yu-Ting Yen, May Chien, Pei-Yi Wu, Shih-Chieh Hung
Commun Biol. 2021; 4: 658. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02175-1
PMCID:
PMC8172534
AbstractArticlePDF–5.1M
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
Inhibition of Protein Phosphatase-2A with LB-100 Enhances Antitumor Immunity Against Glioblastoma
Dominic Maggio, Winson S. Ho, Rebecca Breese, Stuart Walbridge, Herui Wang, Jing Cui, John D. Heiss, Mark R. Gilbert, John S. Kovach, Rongze O. Lu, Zhengping Zhuang
J Neurooncol. Author manuscript; available in PMC 2020 Sep 2.
Published in final edited form as: J Neurooncol. 2020 Jun; 148(2): 231–244. Published online 2020 Apr 27. doi: 10.1007/s11060-020-03517-5
PMCID:
PMC7467059
AbstractArticlePDF–1.8M
18.
Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
Nikita Panicker, Melody Coutman, Charley Lawlor-O’Neill, Richard G. S. Kahl, Séverine Roselli, Nicole M. Verrills
Front Cell Dev Biol. 2020; 8: 358. Published online 2020 Jun 5. doi: 10.3389/fcell.2020.00358
PMCID:
PMC7290052
AbstractArticlePDF–2.8M
19.
PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo
Yu-Ting Yen, May Chien, Yung-Chih Lai, Dao-Peng Chen, Cheng-Ming Chuong, Mien-Chie Hung, Shih-Chieh Hung
Cells. 2020 Jan; 9(1): 90. Published online 2019 Dec 30. doi: 10.3390/cells9010090
PMCID:
PMC7017129
AbstractArticlePDF–4.1M
20.
Vitamin D Receptor Inhibits NLRP3 Activation by Impeding Its BRCC3-Mediated Deubiquitination
Zebing Rao, Xin Chen, Junxian Wu, Mengjun Xiao, Jing Zhang, Binghao Wang, Lei Fang, Hongjie Zhang, Xiaoming Wang, Shuo Yang, Yunzi Chen
Front Immunol. 2019; 10: 2783. Published online 2019 Dec 4. doi: 10.3389/fimmu.2019.02783
PMCID:
PMC6904361
AbstractArticlePDF–4.2M

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